Drews K, et al. Glucosylceramidase Maintains Influenza Infection By Regulating Endocytosis. J Virol. 2019 Mar 27. Abstract
submitted by kickingbird at Mar, 30, 2019 from J Virol. 2019 Mar 27 (via https://jvi.asm.org/content/early/2019/03/25/JVI.00017-19)
Influenza is an RNA virus encapsulated in a lipid bilayer derived from the host cell plasma membrane. Previous studies showed that influenza infection depends on cellular lipids including the sphingolipids ... Gutman SN, et al. Serologic investigation of exposure to influenza A virus H3N2 infection in dogs and cats in the United States. J Vet Diagn Invest. 2019 Mar;31(2):250-254. Abstract
submitted by kickingbird at Mar, 29, 2019 from J Vet Diagn Invest. 2019 Mar;31(2):250-254 (via https://journals.sagepub.com/doi/abs/10.1177/104063871882435)
We investigated, in a cross-sectional study, the prevalence of antibodies against canine influenza A virus (CIV) H3N2 in serum samples collected from dogs and cats using a commercial ELISA and a hemagglutination ... Takashita E, et al. Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan,. Euro Surveill. 2019 Mar;24(12).. Abstract
submitted by kickingbird at Mar, 29, 2019 from Euro Surveill. 2019 Mar;24(12). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically ... Everett HE, et al. Vaccine-mediated protection of pigs against infection with pandemic H1N1 2009 swine influenza A virus requires a close antigenic match between the vaccine antigen and challenge virus. Vaccine. 2019 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2019 from Vaccine. 2019 Mar 23. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Swine influenza A virus (SwIV) infection has considerable economic and animal welfare consequences and, because of the zoonotic potential, can also have public health implications. The 2009 pandemic H1N1 ... Shafiuddin M, Boon ACM. RNA Sequence Features Are at the Core of Influenza a Virus Genome Packaging. J Mol Biol. 2019 Mar 23.. Abstract
submitted by kickingbird at Mar, 29, 2019 from J Mol Biol. 2019 Mar 23. (via https://www.sciencedirect.com/science/article/pii/S002228361)
The influenza A virus (IAV), a respiratory pathogen for humans, poses serious medical and economic challenges to global healthcare systems. The IAV genome, consisting of eight single-stranded viral RNA ... Sun H, et al. H9N2 Viruses Isolated From Mammals Replicated in Mice at Higher Levels Than Avian-Origin Viruses. Front Microbiol. 2019 Mar 11. Abstract
submitted by kickingbird at Mar, 29, 2019 from Front Microbiol. 2019 Mar 11 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0041)
H9N2 subtype influenza A virus (IAV) has more than 20 genotypes that are able to cross species barriers and expand from birds to mammals and humans. To better understand the impact of different H9N2 genotypes ... Wang P, et al. The PB2 Polymerase Host Adaptation Substitutions Prime Avian Indonesia Sub Clade 2.1 H5N1 Viruses for Infecting Humans. Viruses. 2019 Mar 22;11(3).. Abstract
submitted by kickingbird at Mar, 27, 2019 from Viruses. 2019 Mar 22;11(3). (via https://www.mdpi.com/1999-4915/11/3/292)
Significantly higher numbers of human infections with H5N1 virus have occurred in Indonesia and Egypt, compared with other affected areas, and it is speculated that there are specific viral factors for ... Li X, et al. Rapid Evolution and Gene Communication of H3N2 and H1N1 Influenza A Viruses. J Infect. 2019 Mar 22. pii: S0163-4453(19)30094-5.. Abstract
submitted by kickingbird at Mar, 27, 2019 from J Infect. 2019 Mar 22. pii: S0163-4453(19)30094-5. (via https://www.journalofinfection.com/article/S0163-4453(19)300)
?The haplotype network map shows that the 2014 H1N1 strain has gene communication with the 2016/17 H3N2 strain,it may change in the characteristic of the virus by gene communication.?The genetic evolution ... Kode SS, et al. Selection of avian influenza A (H9N2) virus with reduced susceptibility to neuraminidase inhibitors oseltamivir and zanamivir. Virus Res. 2019 Mar 22.. Abstract
submitted by kickingbird at Mar, 27, 2019 from Virus Res. 2019 Mar 22. (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
Identification of amino-acid substitutions in the neuraminidase (NA) of low-pathogenic avian influenza (AI) H9N2 viruses is important to study the susceptibility to NA inhibitors (NAI). To identify mutations ... Rane CK, et al. Development of solitary chemosensory cells in the distal lung after severe influenza injury. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. (via https://www.physiology.org/doi/abs/10.1152/ajplung.00032.201)
H1N1 influenza virus infection induces dramatic and permanent alveolar remodeling mediated by p63+ progenitor cell expansion in both mice and some patients with acute respiratory distress syndrome. This ... Magnen M, et al. Tissue kallikrein (KLK1) regulates alveolar macrophage apoptosis early in influenza virus infection. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 25. (via https://www.physiology.org/doi/abs/10.1152/ajplung.00379.201)
Host cell proteases are involved in influenza pathogenesis. We examined the role of tissue kallikrein 1 (KLK1) by comparing wild-type (WT) and KLK1-deficient mice infected with influenza H3N2 virus. Levels ... She YM, Li X, Cyr TD. Remarkable Structural Diversity of N-Glycan Sulfation on Influenza Vaccines. Anal Chem. 2019 Mar 25.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Anal Chem. 2019 Mar 25. (via https://pubs.acs.org.ccindex.cn/doi/10.1021/acs.analchem.8b0)
Sulfated N-glycans are biologically important structures derived from enzymatically post-glycosylational modifications of glycoproteins in many therapeutic biologics. The high-throughput analysis of sulfated ... H?fer CT, et al. Structural determinants of the interaction between influenza a virus matrix protein M1 and lipid membranes. Biochim Biophys Acta Biomembr. 2019 Mar 19. Abstract
submitted by kickingbird at Mar, 26, 2019 from Biochim Biophys Acta Biomembr. 2019 Mar 19 (via https://www.sciencedirect.com/science/article/pii/S000527361)
Influenza A virus is a pathogen responsible for severe seasonal epidemics threatening human and animal populations every year. One of the ten proteins encoded by the viral genome, the matrix protein M1, ... Stepanova EA, et al. Amino Acid Substitutions N123D and N149D in Hemagglutinin Molecule Enhance Immunigenicity of Live Attenuated Influenza H7N9 Vaccine Strain in Experiment. Bull Exp Biol Med. 2019 Mar 22.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Bull Exp Biol Med. 2019 Mar 22. (via https://link.springer.com/article/10.1007%2Fs10517-019-04407)
We compared three cold-adapted live attenuated influenza vaccine strains prepared by reverse genetics methods on the basis of master donor virus A/Leningrad/134/17/57 and influenza H7N9 strains A/Anhui/1/2013 ... Fujioka Y, et al. A peptide derived from phosphoinositide 3-kinase inhibits endocytosis and influenza virus infection. Cell Struct Funct. 2019 Mar 21.. Abstract
submitted by kickingbird at Mar, 26, 2019 from Cell Struct Funct. 2019 Mar 21. (via https://www.jstage.jst.go.jp/article/csf/advpub/0/advpub_190)
Endocytosis mediates the internalization and ingestion of a variety of endogenous or exogenous substances, including virus particles, under the control of intracellular signaling pathways. We have previously ... Kannan S, Shankar R, Kolandaivel P. Insights into structural and inhibitory mechanisms of low pH-induced conformational change of influenza HA2 protein: a computational approach. J Mol Model. 2019 Mar 23;25(4):99. Abstract
submitted by kickingbird at Mar, 26, 2019 from J Mol Model. 2019 Mar 23;25(4):99 (via https://link.springer.com/article/10.1007%2Fs00894-019-3982-)
Though oseltamivir and zanamivir are the active anti-influenza drugs, the emergence of different strains of influenza A virus with mutations creates drug-resistance to these drugs. Therefore, it is essential ... Akand EH, Downard KM. Mechanisms of Antiviral Resistance in Influenza Neuraminidase Revealed by a Mass Spectrometry Based Phylonumerics Approach. Mol Phylogenet Evol. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2019 from Mol Phylogenet Evol. 2019 Mar 20 (via https://www.sciencedirect.com/science/article/pii/S105579031)
A mass based phylonumerics approach is shown to be able to investigate the origins of the emergence of antiviral resistance mutations in influenza neuraminidase through a global view of mutational trends. ... Yamamoto Y, et al. Peptides with the multibasic cleavage site of the hemagglutinin from highly pathogenic influenza viruses act as cell-penetrating via binding to heparan sulfate and neuropilins. Biochem Biophys Res Commun. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 26, 2019 from Biochem Biophys Res Commun. 2019 Mar 20 (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Cell-penetrating peptides (CPPs) show promise as an attractive delivery vehicle for therapeutic molecules-including nucleic acids, peptides, proteins, and even particulates-into several cell types. It ... Cherdantseva LA, et al. Death Mechanisms of Pulmonary Alveolocytes in Mice Infected with Influenza Viruses A/H1N1/California/04/2009 and A/H5N1/Goose/Krasnoozerskoye/627/05. Bull Exp Biol Med. 2019 Mar 22. Abstract
submitted by kickingbird at Mar, 26, 2019 from Bull Exp Biol Med. 2019 Mar 22 (via https://link.springer.com/article/10.1007%2Fs10517-019-04408)
In CBA mice infected with influenza viruses A/H1N1/California/04/2009 and A/H5N1/Goose/Krasnoozerskoye/627/05 in a dose of 10 MLD50, the mechanisms of death of pulmonary alveolocytes over 10 postinfection ... Amarelle L, et al. Cardiac glycosides decrease influenza virus replication by inhibiting cell protein translational machinery. Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20. Abstract
submitted by kickingbird at Mar, 25, 2019 from Am J Physiol Lung Cell Mol Physiol. 2019 Mar 20 (via https://www.physiology.org/doi/abs/10.1152/ajplung.00173.201)
Cardiac glycosides (CG) are used primarily for cardiac failure and have been reported to have other effects, including inhibition of viral replication. Here we set out to study mechanisms by which CG as ... 5584 items, 20/Page, Page[128/280][|<<] [|<] [121] [122] [123] [124] [125] [126] [127] [128] [129] [130] [>|] [>>|] |
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