Pulit-Penaloza JA, et al. Mammalian pathogenicity and transmissibility of a reassortant Eurasian avian-like A(H1N1v) influenza virus associated with human infection in China (2015). Virology. 2019 Aug 10;537:31-35.. Abstract
submitted by kickingbird at Aug, 21, 2019 from Virology. 2019 Aug 10;537:31-35. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Swine-origin (variant) H1 influenza A viruses associated with numerous human infections in North America in recent years have been extensively studied in vitro and in mammalian models to determine their ... Shen Q, Cho JH. The structure and conformational plasticity of the nonstructural protein 1 of the 1918 influenza A virus. Biochem Biophys Res Commun. 2019 Aug 14.. Abstract
submitted by kickingbird at Aug, 21, 2019 from Biochem Biophys Res Commun. 2019 Aug 14. (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Nonstructural protein 1 (NS1) is a multifunctional virulence factor of influenza virus. The effector domain (ED) of influenza viruses is capable of binding to a variety of host factors, however, the molecular ... Arikata M, et al. Efficacy of clarithromycin against H5N1 and H7N9 avian influenza a virus infection in cynomolgus monkeys. Antiviral Res. 2019 Aug 14:1. Abstract
submitted by kickingbird at Aug, 21, 2019 from Antiviral Res. 2019 Aug 14:1 (via https://www.sciencedirect.com/science/article/pii/S016635421)
Clarithromycin (CAM), a 14-membered ring macrolide, has anti-inflammatory and immunomodulatory actions and antiviral effects in seasonal influenza virus infection. We examined the prophylactic and therapeutic ... Ujie M, et al. Long-term culture of human lung adenocarcinoma A549 cells enhances the replication of human influenza A viruses. J Gen Virol. 2019 Aug 19.. Abstract
submitted by kickingbird at Aug, 21, 2019 from J Gen Virol. 2019 Aug 19. (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Long-term culture of the human lung adenocarcinoma cell line A549 promotes the differentiation of these cells toward an alveolar type II cell phenotype. Here, we evaluated the susceptibility of long-term ... Hay JA, Laurie K, White M, Riley S. Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets. PLoS Comput Biol. 2019 Aug 19;15(8):e1007294. Abstract
submitted by kickingbird at Aug, 21, 2019 from PLoS Comput Biol. 2019 Aug 19;15(8):e1007294 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
The strength and breadth of an individual's antibody repertoire is an important predictor of their response to influenza infection or vaccination. Although progress has been made in understanding qualitatively ... Yu J, et al. Development and characterization of a reverse genetics system for influenza D virus. J Virol. 2019 Aug 14.. Abstract
submitted by kickingbird at Aug, 18, 2019 from J Virol. 2019 Aug 14. (via https://jvi.asm.org/content/early/2019/08/08/JVI.01186-19)
Influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range and a broad geographical distribution. Recent IDV outbreaks in swine, along with serological and genetic evidence of IDV infection ... Calderon BM, et al. Dysregulation of M segment gene expression contributes to influenza A virus host restriction. PLoS Pathog. 2019 Aug 15;15(8):e1007892. Abstract
submitted by kickingbird at Aug, 18, 2019 from PLoS Pathog. 2019 Aug 15;15(8):e1007892 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The M segment of the 2009 pandemic influenza A virus (IAV) has been implicated in its emergence into human populations. To elucidate the genetic contributions of the M segment to host adaptation, and the ... Liu YM, et al. Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication. J Biomed Sci. 2019 Aug 15;26(1):58. Abstract
submitted by kickingbird at Aug, 18, 2019 from J Biomed Sci. 2019 Aug 15;26(1):58 (via https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929)
BACKGROUND: Multiple interplays between viral and host factors are involved in influenza virus replication and pathogenesis. Several small RNAs have recently emerged as important regulators of host response ... Zheng S, et al. Factors associated with fatality due to avian influenza A(H7N9) infection in China. Clin Infect Dis. 2019 Aug 16. Abstract
submitted by kickingbird at Aug, 18, 2019 from Clin Infect Dis. 2019 Aug 16 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BACKGROUND: The high case fatality rate of influenza A H7N9 infected patients has been a major clinical concern.METHODS: To identify the common causes of death due to H7N9 as well as identify risk factors ... Wan H, et al. The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. Nat Microbiol. 2019 Aug 12.. Abstract
submitted by kickingbird at Aug, 15, 2019 from Nat Microbiol. 2019 Aug 12. (via https://www.nature.com/articles/s41564-019-0522-6)
A(H3N2) virus predominated recent influenza seasons, which has resulted in the rigorous investigation of haemagglutinin, but whether neuraminidase (NA) has undergone antigenic change and contributed to ... Eom G, et al. Diagnosis of Tamiflu-Resistant Influenza Virus in Human Nasal Fluid and Saliva using Surface-enhanced Raman Scattering. ACS Sens. 2019 Aug 13.. Abstract
submitted by kickingbird at Aug, 15, 2019 from ACS Sens. 2019 Aug 13. (via https://pubs.acs.org/doi/10.1021/acssensors.9b00697)
Influenza viruses cause respiratory infection, spread through respiratory secretions and are shed into the nasal secretion and saliva specimens. Therefore, nasal fluid and saliva are effective clinical ... Zhao Y, et al. Airborne transmission may have played a role in the spread of 2015 highly pathogenic avian influenza outbreaks in the United States. Sci Rep. 2019 Aug 13;9(1):11755.. Abstract
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 13;9(1):11755. (via https://www.nature.com/articles/s41598-019-47788-z)
The unprecedented 2015 outbreaks of highly pathogenic avian influenza (HPAI) H5N2 in the U.S. devastated its poultry industry and resulted in over $3 billion economic impacts. Today HPAI continues eroding ... Biuso F, et al. Use of lentiviral pseudotypes as an alternative to reassortant or Triton X-100-treated wild-type Influenza viruses in the neuraminidase inhibition enzyme-linked lectin assay. Influenza Other Respir Viruses. 2019 Sep;13(5):504. Abstract
submitted by kickingbird at Aug, 15, 2019 from Influenza Other Respir Viruses. 2019 Sep;13(5):504 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12669)
BACKGROUND: Formulation of neuraminidase (NA) within influenza vaccines is gaining importance in light of recent human studies. The enzyme-linked lectin assay (ELLA) is considered a reliable assay to evaluate ... Zhao P, et al. Semiaquatic mammals might be intermediate hosts to spread avian influenza viruses from avian to human. Sci Rep. 2019 Aug 12;9(1):11641. Abstract
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 12;9(1):11641 (via https://www.nature.com/articles/s41598-019-48255-5)
Avian influenza A viruses (AIVs) can occasionally transmit to mammals and lead to the development of human pandemic. A species of mammal is considered as a mixing vessel in the process of host adaptation. ... Hideshima S, et al. Glycan-immobilized dual-channel field effect transistor biosensor for the rapid identification of pandemic influenza viral particles. Sci Rep. 2019 Aug 12;9(1):11616. Abstract
submitted by kickingbird at Aug, 15, 2019 from Sci Rep. 2019 Aug 12;9(1):11616 (via https://www.nature.com/articles/s41598-019-48076-6)
Pandemic influenza, triggered by the mutation of a highly pathogenic avian influenza virus (IFV), has caused considerable damage to public health. In order to identify such pandemic IFVs, antibodies that ... Dumm RE, Heaton NS. The Development and Use of Reporter Influenza B Viruses. Viruses. 2019 Aug 9;11(8).. Abstract
submitted by kickingbird at Aug, 15, 2019 from Viruses. 2019 Aug 9;11(8). (via https://www.mdpi.com/1999-4915/11/8/736)
Influenza B viruses (IBVs) are major contributors to total human influenza disease, responsible for ~1/3 of all infections. These viruses, however, are relatively less studied than the related influenza ... De Vlugt C, Sikora D, Rocheleau L, Pelchat M. Priming and realignment by the influenza a virus RdRp is dependent on the length of the host primers and the extent of base pairing to viral RNA. Virology. 2019 Aug 2;536:91-100.. Abstract
submitted by kickingbird at Aug, 15, 2019 from Virology. 2019 Aug 2;536:91-100. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Initiation of influenza A virus (IAV) transcription depends on RNA primers derived from host RNAs. During this process, some primers are elongated by a few nucleotides, realigned on the viral RNA templates ... Xiong J, Zhao P, Yang P, Yan Q, Jiang L. Evolutionary dynamics of the H7N9 avian influenza virus based on large-scale sequence analysis. PLoS One. 2019 Aug 12;14(8):e0220249.. Abstract
submitted by kickingbird at Aug, 15, 2019 from PLoS One. 2019 Aug 12;14(8):e0220249. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since 2013, epidemics caused by novel H7N9 avian influenza A viruses (AIVs) have become a considerable public health issue. This study investigated the evolution of these viruses at the population level. ... Khan S, et al. Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes. J Vis Exp. 2019 Jul 26;(149).. Abstract
submitted by kickingbird at Aug, 15, 2019 from J Vis Exp. 2019 Jul 26;(149). (via https://www.jove.com/video/59973/use-an-influenza-antigen-mi)
The influenza virus remains a significant cause of mortality worldwide due to the limited effectiveness of currently available vaccines. A key challenge to the development of universal influenza vaccines ... Li X, et al. Characterization of avian influenza H5N3 reassortants isolated from migratory waterfowl and domestic ducks in China from 2015 to 2018. Transbound Emerg Dis. 2019 Aug 11.. Abstract
submitted by kickingbird at Aug, 15, 2019 from Transbound Emerg Dis. 2019 Aug 11. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13324)
Wild and domestic aquatic birds are the natural reservoirs of avian influenza viruses (AIVs). All subtypes of AIVs, including 16 hemagglutinin (HA) and nine neuraminidase (NA), have been isolated from ... 5584 items, 20/Page, Page[116/280][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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