Perry SS, Brice DC, Sakr AA, Kandeil A, DeBeaucham. Modulation of cytokeratin and cytokine/chemokine expression following influenza virus infection of differentiated human tonsillar epithelial cells. J Virol. 2025 Jan 10:e0146024. Abstract
submitted by kickingbird at Jan, 13, 2025 from J Virol. 2025 Jan 10:e0146024 (via https://journals.asm.org/doi/10.1128/jvi.01460-24)
The tonsils have been identified as a site of replication for Epstein-Barr virus, adenovirus, human papillomavirus, and other respiratory viruses. Human tonsil epithelial cells (HTECs) are a heterogeneous ... Maria Rios Carrasco, etc.,al. [preprint]The Q226L mutation can convert a highly pathogenic H5 2.3.4.4e virus to bind human-type receptors. https://doi.org/10.1101/2025.01.10.632119. Abstract
submitted by kickingbird at Jan, 13, 2025 from https://doi.org/10.1101/2025.01.10.632119 (via https://www.biorxiv.org/content/10.1101/2025.01.10.632119v1)
H5Nx viruses continue to wreak havoc in avian and mammalian species worldwide. The virus distinguishes itself by the ability to replicate to high titers and transmit efficiently in a wide variety of hosts ... Jordan T. Ort, etc.,al. [preprint]Development of avian influenza A(H5) virus datasets for Nextclade enables rapid and accurate clade assignment. https://doi.org/10.1101/2025.01.07.631789. Abstract
submitted by kickingbird at Jan, 12, 2025 from https://doi.org/10.1101/2025.01.07.631789 (via https://www.biorxiv.org/content/10.1101/2025.01.07.631789v1)
The ongoing panzootic of highly pathogenic avian influenza (HPAI) A(H5) viruses is the largest in history, with unprecedented transmission to multiple mammalian species. Avian influenza A viruses of the ... O.P. Zhirnov, A.I. Chernyshova. The Uncleaved Viral Hemagglutinin HA0 Increases Influenza A Virus Resistance to Thermal Pasteurization. Virology. Abstract
submitted by kickingbird at Jan, 11, 2025 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Two biological types of influenza virus are known and distinguished by the structure of the surface glycoprotein, hemagglutinin (HA). The noninfectious virions contain the uncleaved HA0 (80 kDa), whereas ... Greco F, Ravenswater HM, Ruiz-Raya F, D´Avin. Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks. Sci Rep. 2025 Jan 9;15(1):1435. Abstract
submitted by kickingbird at Jan, 11, 2025 from Sci Rep. 2025 Jan 9;15(1):1435 (via https://www.nature.com/articles/s41598-025-85152-6)
Emerging infectious diseases are of major concern to animal and human health. Recent emergence of high pathogenicity avian influenza virus (HPAIV) (H5N1 clade 2.3.4.4b) led to substantial global mortality ... Cao Y, Chin AWH, Gu H, Li M, Gu Y, Lau SPN, et al. An interferon-stimulated long non-coding RNA USP30-AS1 as an immune modulator in influenza A virus infection. PLoS Pathog 21(1): e1012854. Abstract
submitted by kickingbird at Jan, 10, 2025 from PLoS Pathog 21(1): e1012854 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Long non-coding RNAs (lncRNAs) are essential components of innate immunity, maintaining the functionality of immune systems that control virus infection. However, how lncRNAs engage immune responses during ... Thongdee M, Chaiwattanarungruengpaisan S, Ketchim. Evidence of avian and human influenza A virus infection in farmed Siamese crocodiles (Crocodylus siamensis) in Thailand. PLoS ONE 20(1): e0317035. Abstract
submitted by kickingbird at Jan, 10, 2025 from PLoS ONE 20(1): e0317035 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Crocodilians are susceptible to a range of virus infection including influenza A virus (IAV). However, little is known about the ecology and epidemiology of IAV in crocodile species. This study aimed to ... Sun Wanying, Choy Ka Tim, Cheng Ka Man, Brackman C. Detection and characterisation of high pathogenicity avian influenza virus (H5N1/H5N8) clade 2.3.4.4b, Hong Kong SAR, China, 2021 to 2024. Euro Surveill. 2025;30(1):pii=2400839. Abstract
submitted by kickingbird at Jan, 10, 2025 from Euro Surveill. 2025;30(1):pii=2400839 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
First detected in China in 1996, highly pathogenic avian influenza viruses (HPAIV) A(H5N1) within the Goose/Guangdong1/96-lineage have genetically evolved, diverging into multiple clades. Viruses within ... Imai M, Ueki H, Ito M, Iwatsuki-Horimoto K, Kiso M. Highly pathogenic avian H5N1 influenza A virus replication in ex vivo cultures of bovine mammary gland and teat tissues. Emerg Microbes Infect. 2025 Jan 9:2450029. Abstract
submitted by kickingbird at Jan, 10, 2025 from Emerg Microbes Infect. 2025 Jan 9:2450029 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since early 2024, highly pathogenic avian influenza (HPAI) H5N1 viruses, which belong to hemagglutinin (HA) clade 2.3.4.4b genotype B3.13, have been causing outbreaks in dairy cattle in the United States. ... Ge Y, Liu J, Li Y, Peng P, Zhou Y, Yu J, Huo M, Li. Geographical distribution and evolutionary dynamics of H4Nx avian influenza viruses. Front. Microbiol., 07 January 2025. Abstract
submitted by kickingbird at Jan, 10, 2025 from Front. Microbiol., 07 January 2025 (via https://www.frontiersin.org/journals/microbiology/articles/1)
H4Nx avian influenza viruses (AIVs) have been isolated from wild birds and poultry and can also cross the species barrier to infect mammals (pigs and muskrats). The widespread presence of these viruses ... Zhu R, Wu J, Chen R, Zhou M, Cao S, Wu Z, Wang L,. HA198 mutations in H9N2 avian influenza: molecular dynamics insights into receptor binding. Front. Vet. Sci., 08 January 2025. Abstract
submitted by kickingbird at Jan, 10, 2025 from Front. Vet. Sci., 08 January 2025 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Introduction: The H9N2 avian influenza virus is widely disseminated in poultry and poses a zoonotic threat, despite vaccination efforts. Mutations at residue 198 of hemagglutinin (HA) are critical for ... Flagg M, Williamson BN, Ortiz-Morales JS, Lutterma. Comparison of Contemporary and Historic Highly Pathogenic Avian Influenza A(H5N1) Virus Replication in Human Lung Organoids. Emerg Infect Dis. 2025 Feb. Abstract
submitted by kickingbird at Jan, 10, 2025 from Emerg Infect Dis. 2025 Feb (via https://wwwnc.cdc.gov/eid/article/31/2/24-1147_article)
We compared virus replication and host responses in human alveolar epithelium infected with highly pathogenic avian influenza (HPAI) A(H5N1) viruses. A/Vietnam/1203/2004 replicated most efficiently, followed ... Rowe T, Fletcher A, Lange M, Hatta Y, Jasso G, Wen. Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets. mBio. 2025 Jan 8:e0236124. Abstract
submitted by kickingbird at Jan, 9, 2025 from mBio. 2025 Jan 8:e0236124 (via https://journals.asm.org/doi/10.1128/mbio.02361-24)
Due to its natural influenza susceptibility, clinical signs, transmission, and similar sialic acid residue distribution, the ferret is the primary animal model for human influenza research. Antibodies ... Wang, Y., Wang, H., Zhang, Y. et al. Single-dose suraxavir marboxil for acute uncomplicated influenza in adults and adolescents: a multicenter, randomized, double-blind, placebo-controlled phase 3 trial. Nat Med (2025). Abstract
submitted by kickingbird at Jan, 9, 2025 from Nat Med (2025) (via https://www.nature.com/articles/s41591-024-03419-3)
Suraxavir marboxil (GP681) is an antiviral drug inhibiting the polymerase acidic protein (PA) of RNA polymerase, of influenza. It has shown therapeutic activity against influenza A and B virus infections ... Vidhi Dholakia, etc.,al. [preprint]Polymerase mutations underlie adaptation of H5N1 influenza virus to dairy cattle and other mammals. https://doi.org/10.1101/2025.01.06.631435. Abstract
submitted by kickingbird at Jan, 9, 2025 from https://doi.org/10.1101/2025.01.06.631435 (via https://www.biorxiv.org/content/10.1101/2025.01.06.631435v1)
In early 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA. The epidemic remains uncontrolled, with spillbacks into poultry, wild birds ... Manlin He, etc.,al. The H5N6 Virus Containing Internal Genes From H9N2 Exhibits Enhanced Pathogenicity and Transmissibility. Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at Jan, 8, 2025 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/6252849)
The H5N6 avian influenza virus (AIV) is constantly undergoing recombination and evolution with other subtypes of AIV, resulting in various types of recombinant H5N6 viruses. However, the risk to human ... Arvia R, Rocca A, Casciato B, Stincarelli MA, Gian. High-resolution melting analysis for detection of nucleotide mutation markers in the polymerase-acidic (PA) gene of influenza virus that are associated with baloxavir marboxil resistance. Arch Virol. 2025 Jan 6;170(2):29. Abstract
submitted by kickingbird at Jan, 8, 2025 from Arch Virol. 2025 Jan 6;170(2):29 (via https://link.springer.com/article/10.1007/s00705-024-06214-0)
The I38T substitution in the influenza virus polymerase-acidic (PA) subunit is a resistance marker of concern for treatment with the antiviral baloxavir marboxil (BXM). Thus, monitoring PA/I38T mutations ... Tremlett, C. J., Cleasby, I. R., Bolton, M., & Wil. Declines in UK breeding populations of seabird species of conservation concern following the outbreak of high pathogenicity avian influenza (HPAI) in 2021–2022. Bird Study, 1–18. Abstract
submitted by kickingbird at Jan, 6, 2025 from Bird Study, 1–18 (via https://www.tandfonline.com/doi/full/10.1080/00063657.2024.2)
CapsuleUK breeding populations of Great Skua Stercorarius skua, Northern Gannet Morus bassanus, Sandwich Tern Thalasseus sandvicensis and Common Tern Sterna hirundo decreased substantially between the ... Przymencki, M., Beuch, S., Indykiewicz, P., Litwin. Mortality among scarce breeding gulls and terns during a highly pathogenic avian influenza (HPAI) H5N1 virus outbreak in Poland during 2023. Bird Study, 1–10. Abstract
submitted by kickingbird at Jan, 6, 2025 from Bird Study, 1–10 (via https://www.tandfonline.com/doi/full/10.1080/00063657.2024.2)
CapsuleDuring spring and summer 2023, the highly pathogenic avian influenza (HPAI) H5N1 virus caused mass mortality among colony-breeding gulls and terns in Poland.AimsTo document the national impact of ... Altan, E., Avelin, V., Aaltonen, K., Korhonen, E.,. Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in Finland in 2021-2023 – Genetic diversity of the viruses and infection kinetics in human dendritic cells. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Jan, 6, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Highly pathogenic avian influenza (HPAI) H5N1 is known for its virulence and zoonotic potential, infecting birds and mammals, thus raising public health concerns. Since 2021 its spread among birds has ... 5856 items, 20/Page, Page[10/293][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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