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Okda FA, Griffith E, Sakr A, Nelson E, Webby R. New Diagnostic Assays for Differential Diagnosis Between the Two Distinct Lineages of Bovine Influenza D Viruses and Human Influenza C Viruses. Front Vet Sci. 2020 Dec 11;7:605704.  Abstract  
submitted by kickingbird at Dec, 29, 2020 from Front Vet Sci. 2020 Dec 11;7:605704 (via https://www.frontiersin.org/articles/10.3389/fvets.2020.6057)
Influenza D virus (IDV), a novel orthomyxovirus, is currently emerging in cattle worldwide. It shares >50% sequence similarity with the human influenza C virus (HICV). Two clades of IDV are currently co-circulating ...

Bi Y, Li J, Li S, Fu G, Jin T, Zhang C, Yang Y, Ma. Dominant subtype switch in avian influenza viruses during 2016~2019 in China. Nat Commun. 2020 Nov 20;11(1):5909.  Abstract  
submitted by kickingbird at Dec, 28, 2020 from Nat Commun. 2020 Nov 20;11(1):5909 (via https://www.nature.com/articles/s41467-020-19671-3)
We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were collected from May 2016 to February 2019 in 23 ...

Beerens N, Germeraad EA, Venema S, Verheij E, Prit. Comparative pathogenicity and environmental transmission of recent highly pathogenic avian influenza H5 viruses. Emerg Microbes Infect. 2020 Dec 22:1-23.  Abstract  
submitted by kickingbird at Dec, 25, 2020 from Emerg Microbes Infect. 2020 Dec 22:1-23 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Highly pathogenic avian influenza (HPAI) viruses of H5 clade have spread to many countries in Asia, Europe and North America by migratory wild birds, causing outbreaks on hundreds of poultry farms. ...

Liu Y, Fu C, Ye S, Liang Y, Qi Z, Yao C, Wang Z, W. Phosphoproteomics to Characterize Host Response During H3N2 Canine Influenza Virus Infection of Dog Lung. Front Vet Sci. 2020 Dec 3;7:585071.  Abstract  
submitted by kickingbird at Dec, 22, 2020 from Front Vet Sci. 2020 Dec 3;7:585071 (via https://www.frontiersin.org/articles/10.3389/fvets.2020.5850)
Avian-origin H3N2 canine influenza viruses (CIVs) cause severe contagious respiratory disease in dogs, and quickly adapt to new environments. To further understand the mechanism of virus infection and ...

Hu Z, Shi L, Zhao J, Gu H, Hu J, Wang X, Liu X, Hu. Role of the Hemagglutinin Residue 227 in Immunogenicity of H5 and H7 Subtype Avian Influenza Vaccines in Chickens. Avian Dis. 2020 Dec 1;64(4):445-450.  Abstract  
submitted by kickingbird at Dec, 22, 2020 from Avian Dis. 2020 Dec 1;64(4):445-450 (via https://bioone.org/journals/avian-diseases/volume-64/issue-4)
Many H5 and H7 subtype avian influenza vaccines are poorly immunogenic in terms of inducing hemagglutination-inhibition (HI) antibody titers. Residue 227 (H3 numbering) in the receptor binding site in ...

Isoda N, Twabela AT, Bazarragchaa E, Ogasawara K,. Re-Invasion of H5N8 High Pathogenicity Avian Influenza Virus Clade in Hokkaido, Japan, 2020. Viruses. 2020 Dec 14;12(12):E1439.  Abstract  
submitted by kickingbird at Dec, 19, 2020 from Viruses. 2020 Dec 14;12(12):E1439 (via https://www.mdpi.com/1999-4915/12/12/1439)
Global dispersion of high pathogenicity avian influenza (HPAI), especially that caused by H5 clade, has threatened poultry industries and, potentially, human health. An HPAI virus, A/northern pintail/Hokkaido/M13/2020 ...

Zhang J, Chen Y, Shan N, Wang X, Lin S, Ma K, Li B. Genetic diversity, phylogeography, and evolutionary dynamics of highly pathogenic avian influenza A (H5N6) viruses. Virus Evol. 2020 Nov 21;6(2):veaa079.  Abstract  
submitted by kickingbird at Dec, 17, 2020 from Virus Evol. 2020 Nov 21;6(2):veaa079 (via https://academic.oup.com/ve/article/6/2/veaa079/5931525)
From 2013 onwards, the spread of novel H5N6 highly pathogenic avian influenza (HPAI) viruses in China has posed great threats to not only poultry industry but also human health. Since late-2016 in particular, ...

Zhu P, Yi X, Zhang L, Liu Y, Wang S, Gu J, Zhu X,. Identification of H7N9 hemagglutinin novel protein epitopes that elicit strong antibody-dependent, cell-mediated cytotoxic activities with protection from influenza infection in mouse model. Cell Immunol. 2020 Dec 6;359:104255.  Abstract  
submitted by kickingbird at Dec, 16, 2020 from Cell Immunol. 2020 Dec 6;359:104255 (via https://www.sciencedirect.com/science/article/pii/S000887492)
Background: Antibody-dependent cell-mediated cytotoxicity (ADCC) is one of the mechanisms connecting humoral immunity and cellular immunity and has been well-demonstrated in recent studies. Neutralizing ...

Xiang B, Song J, Chen L, Liang J, Li X, Yu D, Lin. Duck-origin H5N6 avian influenza viruses induce different pathogenic and inflammatory effects in mice. Transbound Emerg Dis. 2020 Dec 14.  Abstract  
submitted by kickingbird at Dec, 16, 2020 from Transbound Emerg Dis. 2020 Dec 14 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.13956)
Since 2013, H5N6 highly pathogenic avian influenza viruses have caused considerable economic losses in the poultry industry and have caused 24 laboratory-confirmed human cases. In this study, we isolated ...

Jeong S, Lee DH, Kwon JH, Kim YJ, Lee SH, Cho AY,. Highly Pathogenic Avian Influenza Clade Subtype H5N8 Virus Isolated from Mandarin Duck in South Korea, 2020. Viruses. 2020 Dec 4;12(12):E1389.  Abstract  
submitted by kickingbird at Dec, 10, 2020 from Viruses. 2020 Dec 4;12(12):E1389 (via https://www.mdpi.com/1999-4915/12/12/1389)
In October 2020, a highly pathogenic avian influenza (HPAI) subtype H5N8 virus was identified from a fecal sample of a wild mandarin duck (Aix galericulata) in South Korea. We sequenced all eight genome ...

Bai Y, Lian P, Li J, Zhang Z, Qiao J. The active GLP-1 analogue liraglutide alleviates H9N2 influenza virus-induced acute lung injury in mice. Microb Pathog. 2020 Dec 4:104645.  Abstract  
submitted by kickingbird at Dec, 9, 2020 from Microb Pathog. 2020 Dec 4:104645 (via https://www.sciencedirect.com/science/article/pii/S088240102)
Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected ...

Huang J, Huang N, Fan M, Zhao L, Luo Y, Ding P, Ti. Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus. Virol J. 2020 Dec 7;17(1):191.  Abstract  
submitted by kickingbird at Dec, 9, 2020 from Virol J. 2020 Dec 7;17(1):191 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza virus remains a continuous and severe threat to public health worldwide, and its prevention and treatment have always been a major international issue. Because of its ability to evade ...

van de Wall S, Badovinac VP, Harty JT. Influenza-Specific Lung-Resident Memory CD8 + T Cells. Cold Spring Harb Perspect Biol. 2020 Dec 7:a037978.  Abstract  
submitted by kickingbird at Dec, 9, 2020 from Cold Spring Harb Perspect Biol. 2020 Dec 7:a037978 (via https://cshperspectives.cshlp.org/content/early/2020/12/07/c)
Despite the availability of seasonal vaccines, influenza A (IAV) prevails as a leading cause of respiratory infection worldwide. Current vaccination efforts aim at increasing protection against heterologous ...

Liu Y, Fu C, Lu G, Luo J, Ye S, Ou J, Wang X, Xu H. Comparison of Pathogenicity of Different Infectious Doses of H3N2 Canine Influenza Virus in Dogs. Front Vet Sci. 2020 Nov 13;7:580301.  Abstract  
submitted by kickingbird at Dec, 8, 2020 from Front Vet Sci. 2020 Nov 13;7:580301 (via https://www.frontiersin.org/articles/10.3389/fvets.2020.5803)
The canine influenza virus (CIV) outbreaks have raised concerns as they pose a threat to the health of dogs. The successful construction of a canine influenza (CI) infection model is essential to study ...

Kaplan BS, Falkenberg S, Dassanayake R, Neill J, V. Virus Strain Influenced the Interspecies Transmission of Influenza D Virus Between Calves and Pigs. Transbound Emerg Dis. 2020 Dec 1.  Abstract  
submitted by kickingbird at Dec, 2, 2020 from Transbound Emerg Dis. 2020 Dec 1 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.13943)
Influenza D viruses (IDV) belong to a new genus in the family Orthomyxoviridae. IDV is the etiologic agent of acute, mild respiratory disease in ungulate species with agricultural importance (cattle, pigs, ...

Caddy SL, Vaysburd M, Papa G, Wing M, O´Conn. Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO J. 2020 Dec 1:e106228.  Abstract  
submitted by kickingbird at Dec, 2, 2020 from EMBO J. 2020 Dec 1:e106228 (via https://www.embopress.org/doi/full/10.15252/embj.2020106228)
Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti-N antibodies is clear, their role in immunity is not. This is because while they are ...

Powell JD, Abente EJ, Chang J, Souza CK, Rajao DS,. Characterization of contemporary 2010.1 H3N2 swine influenza A viruses circulating in United States pigs. Virology. 2020 Nov 21;553:94-101.  Abstract  
submitted by kickingbird at Dec, 1, 2020 from Virology. 2020 Nov 21;553:94-101 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
In 2012, swine influenza surveillance detected a novel reassorted influenza A virus (IAV) strain containing human-seasonal hemagglutinin (HA) and neuraminidase (NA). Subsequently, these viruses reassorted, ...

Qian Z, Shou-Yu G, Feng-Xia Z, Peng Y, Wen-Jian S,. Molecular characteristics of H9N2 influenza viruses isolated from farmed raccoon dogs and arctic foxes in China. Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0.  Abstract  
submitted by kickingbird at Nov, 24, 2020 from Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
In this study, eight H9N2 IAVs were isolated from infected diseased, farmed raccoon dogs and arctic foxes. Eight genes shared 98.6%-100% identity among the isolates possessing a PSRSSR/GL motif at the ...

Carrique L, Fan H, Walker AP, Keown JR, Sharps J,. Host ANP32A mediates the assembly of the influenza virus replicase. Nature. 2020 Nov 18.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Nature. 2020 Nov 18 (via https://www.nature.com/articles/s41586-020-2927-z)
Aquatic birds represent a vast reservoir from which new pandemic influenza A viruses can emerge1. Influenza viruses contain a negative-sense segmented RNA genome that is transcribed and replicated by the ...

Bravo-Vasquez N, Yao J, Jimenez-Bluhm P, Meliopoul. Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile. Emerg Infect Dis. 2020 Dec;26(12):2887-2898.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Emerg Infect Dis. 2020 Dec;26(12):2887-2898 (via https://wwwnc.cdc.gov/eid/article/26/12/20-2063_article)
Since their discovery in the United States in 1963, outbreaks of infection with equine influenza virus (H3N8) have been associated with serious respiratory disease in horses worldwide. Genomic analysis ...

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