Hoxie, I., Vasilev, K., Clark, J. et al. A TRAC-478-adjuvanted recombinant N1 neuraminidase influenza virus vaccine induces balanced and broadly protective immune responses. npj Vaccines (2026). Abstract
submitted by kickingbird at May, 3, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01456-2)
Licensed influenza vaccines primarily target the variable hemagglutinin protein and provide inadequate cross-protection against mismatched or drifted viral strains. One promising approach to enhance the ... Mingyue Wang, etc.,al. A novel self-amplified RNA vaccine co-expressing NA and HA1 delivered by Salmonella confers potent protection against H9N2 influenza in chickens. Poultry Science. Abstract
submitted by kickingbird at May, 2, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The ongoing evolution of the H9N2 avian influenza virus presents a growing threat to both the poultry industry and public health. In this context, vaccination is not only a vital preventive measure but ... Ashraf M, Boivin W, Nguyen-Van-Tam JS, Nolan T, St. Development of an adjuvanted, higher-dose, cell-based influenza vaccine: combining advanced technologies to improve vaccine effectiveness. Expert Rev Vaccines. 2026 Apr 29:2667732. Abstract
submitted by kickingbird at May, 1, 2026 from Expert Rev Vaccines. 2026 Apr 29:2667732 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2026.2)
Introduction: Influenza remains a significant public health burden, particularly for high-risk populations such as older adults and those with chronic diseases. Effectiveness of standard-dose egg-grown ... Hao, J., Wang, P., Li, L. et al. Generation of an autophagy-targeting influenza A virus as live attenuated vaccine. Nat Commun (2026). Abstract
submitted by kickingbird at Apr, 30, 2026 from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-72426-4)
Despite existing vaccines, influenza remains a significant public health burden, highlighting the need for vaccine strategies with improved safety and efficacy. Here we develop an autophagy-targeting influenza. ... Xu, Y., Wan, X., Chen, M. et al. Influenza mRNA vaccine with engineered panhandle-forming UTRs provides potent, dose-sparing protection against seasonal influenza viruses. npj Vaccines (2026). Abstract
submitted by kickingbird at Apr, 29, 2026 from npj Vaccines (2026) (via https://www.nature.com/articles/s41541-026-01463-3)
Influenza viruses pose a persistent threat to global public health, causing widespread respiratory illness and significant morbidity. Vaccination remains the most effective strategy to reduce the burden ... Catherine A Cosgrove, Andrei Avanesov, Dondi Rust,. A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults. Clinical Infectious Diseases, 2026;, ciag278. Abstract
submitted by kickingbird at Apr, 26, 2026 from Clinical Infectious Diseases, 2026;, ciag278 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
BackgroundInfluenza A viruses pose a persistent pandemic threat. We report safety, reactogenicity, and immunogenicity findings for mRNA-1018 pandemic influenza vaccine candidates from a phase 1/2 study ... Hertoghs, N., Tang, C., van Paassen, V. et al. A group 1 hemagglutinin stem vaccine elicits broad humoral responses against influenza in phase 1/2a study. Nat Commun 17, 3451 (2026). Abstract
submitted by kickingbird at Apr, 22, 2026 from Nat Commun 17, 3451 (2026) (via https://link.springer.com/article/10.1038/s41467-026-70396-1)
Vaccines targeting the conserved stem region of influenza hemagglutinin (HA) may induce broad immunity and reduce reliance on strain-matched seasonal formulations. This Phase 1/2a study evaluates safety ... Giersch, K., N?rz, D., Grunwald, M. et al. Adaptation and validation of an influenza A subtyping panel for detection of H1pdm09, H3 and H5 on a high-throughput RT-qPCR system. Sci Rep 16, 12888 (2026). Abstract
submitted by kickingbird at Apr, 21, 2026 from Sci Rep 16, 12888 (2026) (via https://www.nature.com/articles/s41598-026-45563-5)
Facing the emergence of highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b in birds and its circulation in dairy cattle, rapid and reliable assays to detect HPAIV infection in humans are ... Se-Hee An, etc.,al. Development of multiplex real-time RT-PCR assays for the simultaneous detection and lineage differentiation of H9 avian influenza viruses. Poultry Science. Abstract
submitted by kickingbird at Apr, 16, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
H9 avian influenza viruses (AIVs) have caused continuous economic losses in poultry and pose a risk of introducing novel lineages through wild birds and human activities, highlighting the importance of ... Marotta MG, Mapulanga T, Maina M, Daly J, Camero M. Development and Qualification of a Pseudotyped Virus-Based Microneutralisation Assay for Influenza D Virus. Influenza Other Respir Viruses. 2026 Apr;20(4):e70. Abstract
submitted by kickingbird at Apr, 15, 2026 from Influenza Other Respir Viruses. 2026 Apr;20(4):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70245)
Background: Epidemiological surveillance of influenza D virus (IDV) has gained increased priority following recent serological findings indicating its potential zoonosis in humans. In this context, it ... Hongli Li, etc.,al. Preclinical evaluation of an mRNA vaccine developed from the first human isolate of bovine H5N1. Cell Reports Medicine. Abstract
submitted by kickingbird at Apr, 9, 2026 from Cell Reports Medicine (via https://www.sciencedirect.com/science/article/pii/S266637912)
Given the global threat posed by H5N1 clade 2.3.4.4b avian influenza, rapid development of effective vaccines is imperative. We design an mRNA vaccine encoding hemagglutinin (HA) from A/Texas/37/2024, ... Paravicini T, Nüesch-Inderbinen M, Mader M, Darpel. No Evidence for Highly Pathogenic Avian Influenza H5N1 Virus in Direct-To-Consumer Raw Cow’s Milk Samples in Switzerland. Dairy. 2026; 7(2):29. Abstract
submitted by kickingbird at Apr, 4, 2026 from Dairy. 2026; 7(2):29 (via https://www.mdpi.com/2624-862X/7/2/29)
Highly pathogenic avian influenza virus (HPAIV) H5N1 has been detected in dairy cattle in the United States, with high viral loads observed in milk from infected animals. This raises public health concerns ... Eom, G. D., Chu, K. B., Yoon, K. W., Mao, J., Heo,. Self-assembled influenza a neuraminidase virus-like particle vaccination confers protection against influenza B virus. Nanomedicine, 1–11. Abstract
submitted by kickingbird at Apr, 4, 2026 from Nanomedicine, 1–11 (via https://www.tandfonline.com/doi/full/10.1080/17435889.2026.2)
BackgroundNeuraminidase has gained increasing attention as a broadly reactive influenza vaccine antigen capable of mitigating the strain-specific limitations of hemagglutinin-based vaccines.MethodsWe generated ... Joy-Yan Lam, etc.,al. Nasal RNA-scaffold-protein vaccine protects mice from human H5N1 clade 2.3.4.4b virus lethal infection and safeguards against vaccine-unmatched viruses. eBioMedicine. Abstract
submitted by kickingbird at Mar, 25, 2026 from eBioMedicine (via https://www.sciencedirect.com/science/article/pii/S235239642)
BackgroundRecent cases of H5N1 avian influenza spilling over into human populations have raised concerns once again about the unpredictable emergence of zoonotic viral diseases. This phenomenon highlights ... Matthys A, Amelinck L, Smet A, Ysenbaert T, Vogel. Internal gene segments from a mouse-adapted influenza B virus confer increased pathogenicity to mice. PLoS One. 2026 Mar 23;21(3):e0335324. Abstract
submitted by kickingbird at Mar, 24, 2026 from PLoS One. 2026 Mar 23;21(3):e0335324 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Influenza B viruses (IBVs) contribute significantly to the annual influenza epidemics in human. Most IBV strains are non- or poorly pathogenic in mice, which are frequently used for vaccine studies. We ... J.Charostad, Z.-a.Ghoreshi, N.Arefinia, et al. Aptamer-Based Approaches for Influenza Virus Detection: A Systematic Review. Health Science Reports9 (2026): e72118. Abstract
submitted by kickingbird at Mar, 19, 2026 from Health Science Reports9 (2026): e72118 (via https://onlinelibrary.wiley.com/doi/10.1002/hsr2.72118)
Background and AimsInfluenza remains a globally prevalent respiratory infection that is challenging to diagnose accurately. This systematic review focuses on aptamer-based tools for influenza virus detection, ... Caroline Dingle, etc.,al. An assessment of the ongoing live bird trade in Hong Kong, an Asian wildlife trade hub. Global Ecology and Conservation. Abstract
submitted by kickingbird at Mar, 5, 2026 from Global Ecology and Conservation (via https://www.sciencedirect.com/science/article/pii/S235198942)
Wildlife trade threatens bird populations around the globe. Throughout Asia, birds are sold for food, pets, religious practices and competitions. Hong Kong SAR has long played an important role in bird ... Li Wang, Jieru Wang, Jaber Hossain, Hans C Cooper,. Development and Characterization of Candidate Vaccine Viruses against High Pathogenicity Avian Influenza A(H5) Viruses for Rapid Pandemic Response. The Journal of Infectious Diseases, 2026. Abstract
submitted by kickingbird at Mar, 2, 2026 from The Journal of Infectious Diseases, 2026 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
High pathogenicity avian influenza A(H5) viruses pose a pandemic threat. These viruses have rapidly evolved in birds and frequently crossed species barriers, resulting in over 1,000 confirmed human infections, ... WHO. Recommendations for influenza vaccine composition for the 2026-2027 northern hemisphere season. WHO. Full Text
submitted by kickingbird at Feb, 27, 2026 from WHO (via https://www.who.int/news/item/27-02-2026-recommendations-for)
The World Health Organization (WHO) today announced recommendations for the viral composition of influenza (or “flu”) vaccines for the 2026-2027 northern hemisphere influenza season. The announcement was ... Pessoa N, Berube N, Aubrey L, Van Kessel J, Javed. Evaluation of beta-propiolactone and AVL-ethanol inactivation protocols for highly pathogenic avian influenza virus in allantoic fluid and cell culture. Appl Environ Microbiol. 2026 Feb 24:e0214425. Abstract
submitted by kickingbird at Feb, 26, 2026 from Appl Environ Microbiol. 2026 Feb 24:e0214425 (via https://journals.asm.org/doi/10.1128/aem.02144-25)
Highly pathogenic avian influenza (HPAI) H5N1 recently expanded its host range to include dairy cattle, and since March 2024, there have been over 1,000 cases reported in the United States. This circulation ... 362 items, 20/Page, Page[2/19][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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