Kang H, Gao J, Giurgea L, Memoli MJ, Daniels R. ELISA-based quantification of neuraminidase in commercial influenza vaccines using virus-derived reference antigens. Microbiol Spectr 0:e01227-26. Abstract
submitted by kickingbird at Jun, 25, 2026 from Microbiol Spectr 0:e01227-26 (via https://journals.asm.org/doi/10.1128/spectrum.01227-26)
Most commercial influenza vaccines are produced using inactivated viruses decorated with hemagglutinin (HA) and neuraminidase (NA) antigens from the recommended strains. However, only the HA antigen content ... Esfandiari AH, Afarande H, Amini VR, Hatamluyi B,. Aptamer-based biosensing strategies for influenza virus detection: a systematic and critical review of electrochemical and optical platforms. Crit Rev Clin Lab Sci. 2026 Jun 23:1-25. Abstract
submitted by kickingbird at Jun, 24, 2026 from Crit Rev Clin Lab Sci. 2026 Jun 23:1-25 (via https://www.tandfonline.com/doi/full/10.1080/10408363.2026.2)
Influenza virus remains a major global health challenge due to its genetic variability and frequent emergence of novel strains. Subtyping is determined by the diverse arrangements of hemagglutinin (HA) ... Grant P Higerd-Rusli, Seth A Hoffman, Abraar Karan. Lower limit of detection of commercial respiratory virus reverse transcriptase–polymerase chain reaction panels for bovine influenza A(H5N1). American Journal of Clinical Pathology, Volume 16. Abstract
submitted by kickingbird at Jun, 24, 2026 from American Journal of Clinical Pathology, Volume 16 (via https://academic.oup.com/ajcp/article-abstract/165/6/aqag067)
ObjectivesThe adaptation of clade 2.3.4.4b influenza A(H5N1) to dozens of mammalian species, including dairy cattle, raises concerns about potential spillover into humans. If the virus develops human-to-human ... Jiachen Liu, etc.,al. Engineered Bacillus subtilis to deliver dsRNA via extracellular vesicles against the H9N2 avian influenza virus. Trends in Biotechnology, 2026. Abstract
submitted by kickingbird at Jun, 21, 2026 from Trends in Biotechnology, 2026 (via https://www.cell.com/trends/biotechnology/fulltext/S0167-779)
RNA interference (RNAi) is a potent antiviral approach, outperforming traditional pesticides and broad-spectrum drugs. Its use in animal disease control faces two challenges: inefficient target design ... Wei, D., Pan, Y., Zhang, X. et al. A bivalent mRNA–LNP vaccine confers broad-spectrum protection against both homologous and heterologous H5/H7 highly pathogenic avian influenza viruses in SPF chickens. Vet Res 57, 111 (2026). Abstract
submitted by kickingbird at Jun, 20, 2026 from Vet Res 57, 111 (2026) (via https://link.springer.com/article/10.1186/s13567-026-01790-2)
The continuous evolution and co-circulation of H5 and H7 subtype highly pathogenic avian influenza viruses (HPAIVs) have caused substantial economic losses to the global poultry industry and pose a persistent ... Peng, C., Zhang, C. & Jiang, T. Validation of a Qualitative Detection Method for Influenza A Virus RNA Based on the RT-RPA-CRISPR/Cas13a System. Curr Microbiol 83, 437 (2026). Abstract
submitted by kickingbird at Jun, 20, 2026 from Curr Microbiol 83, 437 (2026) (via https://link.springer.com/article/10.1007/s00284-026-05028-4)
Seasonal influenza A virus (IAV) frequently causes outbreaks, creating an urgent need for rapid, cost-effective detection. Existing methods have limitations: antigen tests lack sensitivity, RT-qPCR (the ... Ao Z, Vendramelli R, Buyu M, Truong T, Liu D, Gao. A VSV-vector vaccine simultaneously targeting H5N1 hemagglutinin and matrix protein 2 induces robust neutralizing and ADCC antibody responses and provides full protection against lethal H5N1 infection. J Virol 0:e00097-26. Abstract
submitted by kickingbird at Jun, 18, 2026 from J Virol 0:e00097-26 (via https://journals.asm.org/doi/10.1128/jvi.00097-26)
Avian influenza A viruses, especially highly pathogenic avian influenza (HPAI) viruses, pose a significant public health threat, and a multivalent vaccine is the primary prophylactic measure to control ... Harrington WN, Brice DC, Schmitz AJ, Turner JS, Br. Broadly reactive human monoclonal antibodies targeting influenza a nucleoprotein lack protective activity in vivo. Sci Rep. 2026 Jun 16. Abstract
submitted by kickingbird at Jun, 18, 2026 from Sci Rep. 2026 Jun 16 (via https://www.nature.com/articles/s41598-026-58084-y)
The antibody response to influenza virus infection targets numerous viral proteins, with those specific for the hemagglutinin (HA) and neuraminidase (NA) surface glycoproteins being the most extensively ... Ueki H, Tomita Y, Duong C, Mitake H, Kiso M, Furus. A CRISPR knockout mouse library for functional genomics in influenza research. Cell. 2026 Jun 16:S0092-8674(26)00591-X. Abstract
submitted by kickingbird at Jun, 18, 2026 from Cell. 2026 Jun 16:S0092-8674(26)00591-X (via https://www.cell.com/cell/abstract/S0092-8674(26)00591-X)
Functional validation of host factors in whole-animal models is a major bottleneck in virology; it hinders the translation of data from in vitro studies into a deeper understanding of the viral life cycle ... Xiang F, Xu Y, Liu C, Li X, Wang R, Zhang H, Dong. A reverse genetics-based NS1-truncated live attenuated vaccine confers broad heterologous protection against swine influenza viruses. Microb Pathog. 2026 Jun 16:108638. Abstract
submitted by kickingbird at Jun, 18, 2026 from Microb Pathog. 2026 Jun 16:108638 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Swine influenza A viruses (swIAVs) undergo frequent reassortment and evolution, posing significant threats to both animal and human health. In this study, we employed reverse genetics to generate five ... Takahashi K, Takeda Y, Nishiyama K, Fukuyama M, Ma. Detection of H5 subtype avian influenza virus in avian oropharyngeal swab samples using a microfluidic non-competitive fluorescence polarization immunoassay. Analyst. 2026 Jun 17. Abstract
submitted by kickingbird at Jun, 18, 2026 from Analyst. 2026 Jun 17 (via https://pubs.rsc.org/en/content/articlelanding/2026/an/d6an0)
Rapid and simple methods for on-site detection of avian influenza virus (AIV) are essential for effective field surveillance. In this study, a microfluidic device-based non-competitive fluorescence polarization ... Matz HC, Yu TG, Dixit K, Kikawa C, Zhou JQ, Pena A. mRNA-based influenza vaccine expands the B cell response breadth in humans. Nat Immunol. 2026 Jun 15. Abstract
submitted by kickingbird at Jun, 17, 2026 from Nat Immunol. 2026 Jun 15 (via https://www.nature.com/articles/s41590-026-02569-5)
Conventional influenza virus vaccines induce antibody responses of limited breadth. Whether mRNA-based influenza virus vaccines can induce a superior germinal center (GC) response in humans remains unclear. ... Hastie, A., Gupta, V., Lese, P., Moya, J., Schoonb. Immunogenicity and safety of AS03-adjuvanted A/Astrakhan/3212/2020 (H5N8)-like influenza vaccine in adults: Phase 1/2, observer-blinded, randomized trial. Human Vaccines & Immunotherapeutics, 22(1). Abstract
submitted by kickingbird at Jun, 15, 2026 from Human Vaccines & Immunotherapeutics, 22(1) (via https://www.tandfonline.com/doi/full/10.1080/21645515.2026.2)
Influenza pandemics arise from novel influenza A viruses. Recent emergence of a new clade (2.3.4.4.b) of the highly pathogenic H5N1 in animals and humans highlighted its pandemic potential. We evaluated ... Chadwick C, Sparrow E, Nannei C, Taaffe J, Ampofo. Influenza Vaccine Technology Transfer: A Mixed-Methods Study with Vaccine Manufacturers and Global Experts to Assess Successes, Challenges, and Opportunities. Vaccines. 2026; 14(6):522. Abstract
submitted by kickingbird at Jun, 13, 2026 from Vaccines. 2026; 14(6):522 (via https://www.mdpi.com/2076-393X/14/6/522)
Background/Objectives: Technology transfer (TT) has been identified as a global health priority due to its impact on improving access to vaccines, including for pandemic influenza preparedness and response ... Chen T, Huang Q, Chen X, Zhu J, Kong D, Liao X, Li. Trimeric hemagglutinin vaccine provides chickens complete protection against lethal H5 subtype avian influenza virus from clade 2.3.4.4b. Emerg Microbes Infect. 2026 Dec;15(1):2678649. Abstract
submitted by kickingbird at Jun, 11, 2026 from Emerg Microbes Infect. 2026 Dec;15(1):2678649 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
H5 subtype highly pathogenic avian influenza virus (HPAIV) of clade 2.3.4.4b has prevailed globally, causing economic losses in the poultry industry and posing zoonotic threats. While inactivated vaccines ... Guo B, Li Y, Shi M, Zhang J, Wu Q, Wu X, An R, Wan. A triplex-readout CRISPR-Cas12a multimodal biosensing platform for point-of-care detection of avian influenza H5. J Hazard Mater. 2026 Jun 1;514:142562. Abstract
submitted by kickingbird at Jun, 11, 2026 from J Hazard Mater. 2026 Jun 1;514:142562 (via https://www.sciencedirect.com/science/article/pii/S030438942)
The highly pathogenic avian influenza A (H5N1) virus poses a significant zoonotic threat to public and animal health. Conventional detection methods often face limitations in complexity, time, and equipment ... Smith, E.L., Jin, Y., Miller, M.R. et al. Development of Fit-for-Purpose, High Quality Proficiency Samples for Interlaboratory Evaluation of RT-PCR Detection of HPAI H5N1 in Milk. Food Environ Virol 18, 28 (2026). Abstract
submitted by kickingbird at Jun, 9, 2026 from Food Environ Virol 18, 28 (2026) (via https://link.springer.com/article/10.1007/s12560-026-09699-x)
The increased demand for highly pathogenic avian influenza (HPAI) testing in milk highlights the critical need for well-characterized samples that enable meaningful evaluation of current detection methods. ... Abdelaal, A. M., Mahmoud, S. H., Shehata, M. R., T. Comparative immunogenicity and cross-protection of wild-type and reverse genetics H5N8 (clade 2.3.4.4b) oil-adjuvanted vaccines against circulating H5N1 avian influenza viruses from clades 2.3.4.4b an. Avian Pathology, 1–14. Abstract
submitted by kickingbird at Jun, 8, 2026 from Avian Pathology, 1–14 (via https://www.tandfonline.com/doi/full/10.1080/03079457.2026.2)
Highly pathogenic avian influenza (HPAI) H5N8 viruses of clade 2.3.4.4b continue to cause devastating outbreaks worldwide, necessitating effective vaccination strategies. The comparative efficacy of wild-type ... Bin Guo, etc.,al. A Triplex-Readout CRISPR-Cas12a Multimodal Biosensing Platform for Point-of-Care Detection of Avian Influenza H5N1. Journal of Hazardous Materials. Abstract
submitted by kickingbird at Jun, 5, 2026 from Journal of Hazardous Materials (via https://www.sciencedirect.com/science/article/abs/pii/S03043)
The highly pathogenic avian influenza A (H5N1) virus poses a significant zoonotic threat to public and animal health. Conventional detection methods often face limitations in complexity, time, and equipment ... Chenchen Feng, etc.,al. A DirectView focus reduction assay for high-throughput quantification of neutralizing antibodies against influenza A and B viruses. Cell Reports Method. Abstract
submitted by kickingbird at Jun, 5, 2026 from Cell Reports Method (via https://www.sciencedirect.com/science/article/pii/S266723752)
Robust and scalable measurement of neutralizing antibodies is critical for influenza surveillance, vaccine development, and outbreak preparedness. Although focus reduction assay (FRA) is widely used to ... 398 items, 20/Page, Page[2/20][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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