Tang J, Gao R, Liu L, Zhang S, Liu J, Li X, Fang Q. Substitution of I222L-E119V in neuraminidase from highly pathogenic avian influenza H7N9 virus exhibited synergistic resistance effect to oseltamivir in mice. Sci Rep. 2021 Aug 11;11(1):16293. Abstract
submitted by kickingbird at Aug, 13, 2021 from Sci Rep. 2021 Aug 11;11(1):16293 (via https://www.nature.com/articles/s41598-021-95771-4)
That the high frequency and good replication capacity of strains with reduced susceptibility to neuraminidase inhibitors (NAIs) in highly pathogenic avian influenza H7N9 (HPAI H7N9) virus made it a significance ... Tang H, Jianshen C, Zou L, Cai C, Wang Y, Robertso. A mixed-methods study of stakeholders´ practices and attitudes on avian influenza H7N9 vaccination for the yellow broiler industry in Guangxi, China. Transbound Emerg Dis. 2021 Aug 11. Abstract
submitted by kickingbird at Aug, 12, 2021 from Transbound Emerg Dis. 2021 Aug 11 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14286)
In response to a sudden increase in H7N9 human infections, China introduced a H5/H7 bivalent inactivated vaccine for poultry in Guangxi and Guangdong provinces in July 2017, which subsequently became integrated ... Xu X, Zhang L, Chu JTS, Wang Y, Chin AWH, Chong TH. A novel mechanism of enhanced transcription activity and fidelity for influenza A viral RNA-dependent RNA polymerase. Nucleic Acids Res. 2021 Aug 11:gkab660.. Abstract
submitted by kickingbird at Aug, 12, 2021 from Nucleic Acids Res. 2021 Aug 11:gkab660. (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
During RNA elongation, the influenza A viral (IAV) RNA-dependent RNA polymerase (RdRp) residues in the active site interact with the triphosphate moiety of nucleoside triphosphate (NTP) for catalysis. ... Kaplan BS, Anderson TK, Chang J, Santos J, Perez D. Evolution and antigenic advancement of N2 neuraminidase of swine influenza A viruses circulating in the United States following two separate introductions from human seasonal viruses. J Virol. 2021 Aug 11:JVI0063221. Abstract
submitted by kickingbird at Aug, 12, 2021 from J Virol. 2021 Aug 11:JVI0063221 (via https://journals.asm.org/doi/10.1128/JVI.00632-21)
Two separate introductions of human seasonal N2 neuraminidase genes were sustained in United States swine since 1998 (N2-98) and 2002 (N2-02). Herein, we characterized the antigenic evolution of the N2 ... Sakala IG, Honda-Okubo Y, Li L, Baldwin J, Petrovs. A M2 protein-based universal influenza vaccine containing Advax-SM adjuvant provides newborn protection via maternal or neonatal immunization. Vaccine. 2021 Aug 3:S0264-410X(21)00914-2. Abstract
submitted by kickingbird at Aug, 9, 2021 from Vaccine. 2021 Aug 3:S0264-410X(21)00914-2 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Background: Despite newborns being at increased risk of serious influenza infection, influenza vaccines are currently not recommended for use in infants under 6 months of age. We therefore sought to evaluate ... Yang F, Xiao Y, Liu F, Cheng L, Yao H, Wu N, Wu H. Genetic analysis and biological characteristics of novel clade 2.3.4.4 reassortant H5N6 avian influenza viruses from poultry in Eastern China in 2016. Int J Infect Dis. 2021 Aug 5:S1201-9712(21)00632-9. Abstract
submitted by kickingbird at Aug, 9, 2021 from Int J Infect Dis. 2021 Aug 5:S1201-9712(21)00632-9 (via https://www.ijidonline.com/article/S1201-9712(21)00632-9/ful)
Objectives: The continuous evolution of highly pathogenic H5N6 avian influenza viruses (AIVs) causes outbreaks in wildfowls and poultry and occasional human infections. To better understand the genetic ... Del Rosario JMM, da Costa KAS, Asbach B, Ferrara F. Exploiting Pan Influenza A and Pan Influenza B Pseudotype Libraries for Efficient Vaccine Antigen Selection. Vaccines (Basel). 2021 Jul 5;9(7):741. Abstract
submitted by kickingbird at Aug, 9, 2021 from Vaccines (Basel). 2021 Jul 5;9(7):741 (via https://www.mdpi.com/2076-393X/9/7/741)
We developed an influenza hemagglutinin (HA) pseudotype library encompassing Influenza A subtypes HA1-18 and Influenza B subtypes (both lineages) to be employed in influenza pseudotype microneutralization ... El-Husseiny MH, Hagag NM, Pushko P, Tretyakova I,. Evaluation of Protective Efficacy of Influenza Virus Like Particles Prepared from H5N1 Virus of Clade 2.2.1.2 in Chickens. Vaccines (Basel). 2021 Jul 1;9(7):715. Abstract
submitted by kickingbird at Aug, 9, 2021 from Vaccines (Basel). 2021 Jul 1;9(7):715 (via https://www.mdpi.com/2076-393X/9/7/715)
Highly pathogenic Avian Influenza (HPAI) viruses continue to cause severe economic losses in poultry species worldwide. HPAI virus of subtype H5N1 was reported in Egypt in 2006, and despite vaccination ... Zhang S, Tang X, Wang S, Shi F, Duan C, Bi F, Suo. Establishment of Recombinant Eimeria acervulina Expressing Multi-Copies M2e Derived from Avian Influenza Virus H9N2. Vaccines (Basel). 2021 Jul 16;9(7):791. Abstract
submitted by kickingbird at Aug, 9, 2021 from Vaccines (Basel). 2021 Jul 16;9(7):791 (via https://www.mdpi.com/2076-393X/9/7/791)
The potential of Eimeria parasites as live vaccine vectors has been reported with successful genetic manipulation on several species like E. tenella, E. mitis and E. necatrix. Among seven Eimeria species ... Liu Y, Liu C, Dang A, Sun S, Zhang D, Wang M, Chen. Pathological analysis and genetic characterization of the first outbreak H5N8 subtype avian influenza virus isolated from wild swan in Shandong, China. Transbound Emerg Dis. 2021 Aug 6. Abstract
submitted by kickingbird at Aug, 9, 2021 from Transbound Emerg Dis. 2021 Aug 6 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14279)
In January 2021, an outbreak of H5N8 subtype avian influenza was identified from wild mute swans (Cygnus olor) in an overwintering site located within Yellow River Delta Nature Reserve in Shandong, China ... Lee YN, Lee DH, Shin JI, Si YJ, Lee JH, Baek YG, H. Pathogenesis and genetic characteristics of a novel reassortant low pathogenic avian influenza A(H7N6) virus isolated in Cambodia in 2019. Transbound Emerg Dis. 2021 Aug 4.. Abstract
submitted by kickingbird at Aug, 5, 2021 from Transbound Emerg Dis. 2021 Aug 4. (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14256)
The first human case of zoonotic A(H7N4) avian influenza virus (AIV) infection was reported in early 2018 in China. Two months after this case, novel A(H7N4) viruses phylogenetically related to the Jiangsu ... Finch J, Zuckerman M, Smith M. Investigating the potential sequence variation in the influenza A matrix genes during the 2018-2019 season in samples from a local population in London. J Virol Methods. 2021 Jul 30:114250.. Abstract
submitted by kickingbird at Aug, 4, 2021 from J Virol Methods. 2021 Jul 30:114250. (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Recent publications have highlighted the emergence of mutations in the M1 gene of both influenza A H1N1pdm09 and H3N2 subtypes affecting the performance of commercial RT-PCR assays. Respiratory samples ... Han AX, Felix Garza ZC, Welkers MR, Vigeveno RM, T. Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children. Elife. 2021 Aug 3;10:e68917. Abstract
submitted by kickingbird at Aug, 4, 2021 from Elife. 2021 Aug 3;10:e68917 (via https://elifesciences.org/articles/68917)
The evolution of influenza viruses is fundamentally shaped by within-host processes. However, the within-host evolutionary dynamics of influenza viruses remain incompletely understood, in part because ... Spackman E, Pantin-Jackwood MJ, Sitaras I, Stephen. Identification of Efficacious Vaccines Against Contemporary North American H7 Avian Influenza Viruses. Avian Dis. 2021 Mar;65(1):113-121. Abstract
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):113-121 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Five vaccines, including four inactivated, whole-virus water-in-oil adjuvanted vaccines and a commercial nonreplicating alphavirus-vectored RNA particle (RP) vaccine were evaluated in chickens for their ... Wang Y, Chen X, Yuan Y. Antibody Response of an H9 Subtype Avian Influenza Poultry Vaccine on Three Kinds of Wild Birds in Shanghai Zoo. Avian Dis. 2021 Mar;65(1):90-94. Abstract
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):90-94 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
A semiannual immunization with a commercial inactivated H9 subtype avian influenza virus (AIV) vaccine developed for poultry has been used to prevent and control the avian influenza (AI) infections among ... Lee DH, Killian ML, Deliberto TJ, Wan XF, Lei L, S. H7N1 Low Pathogenicity Avian Influenza Viruses in Poultry in the United States During 2018. Avian Dis. 2021 Mar;65(1):59-62.. Abstract
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):59-62. (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Here, we report three detections of H7N1 low pathogenicity avian influenza viruses (LPAIV) from poultry in Missouri (n = 2) and Texas (n = 1) during February and March 2018. Complete genome sequencing ... Fellahi S, Nassik S, Maaroufi I, Tligui NS, Touzan. Pathogenesis of Avian Influenza Virus Subtype H9N2 in Turkeys and Evaluation of Inactivated Vaccine Efficacy. Avian Dis. 2021 Mar;65(1):46-51. Abstract
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):46-51 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Avian influenza H9N2 viruses circulate in all types of poultry species, including turkeys, and cause significant losses for the poultry industry in many parts of the word. The aim of this study was to ... Sangsiriwut K, Noisumdaeng P, Uiprasertkul M, Pras. Full Genomic Sequences of H5N1 Highly Pathogenic Avian Influenza Virus in Human Autopsy Specimens Reveal Genetic Variability and Adaptive Changes for Growth in MDCK Cell Cultures. Biomed Res Int. 2021 Jul 22;2021:3890681. Abstract
submitted by kickingbird at Aug, 3, 2021 from Biomed Res Int. 2021 Jul 22;2021:3890681 (via https://www.hindawi.com/journals/bmri/2021/3890681/)
The entire H5N1 highly pathogenic avian influenza viral genomes were identified in the frozen autopsy specimens: the trachea, lung, colon, and intestinal feces from a patient who died of the disease in ... Nudelman I, Kudrin D, Nudelman G, Deshpande R, Har. Comparing Host Module Activation Patterns and Temporal Dynamics in Infection by Influenza H1N1 Viruses. Front Immunol. 2021 Jul 14;12:691758.. Abstract
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:691758. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6917)
Influenza is a serious global health threat that shows varying pathogenicity among different virus strains. Understanding similarities and differences among activated functional pathways in the host responses ... Hernandez-Davies JE, Felgner J, Strohmeier S, Pone. Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components. Front Immunol. 2021 Jul 14;12:692151.. Abstract
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:692151. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6921)
Combining variant antigens into a multivalent vaccine is a traditional approach used to provide broad coverage against antigenically variable pathogens, such as polio, human papilloma and influenza viruses. ... 7775 items, 20/Page, Page[92/389][|<<] [|<] [91] [92] [93] [94] [95] [96] [97] [98] [99] [100] [>|] [>>|] |
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