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2020-3-31 17:32:24
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Carnaccini S, Perez DR. H9 Influenza Viruses: An Emerging Challenge. Cold Spring Harb Perspect Med. 2019 Dec 23.  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Influenza A viruses (IAVs) of the H9 subtype are enzootic in Asia, the Middle East, and parts of North and Central Africa, where they cause significant economic losses to the poultry industry. Of note, ...

Ludwig S, Hrincius ER, Boergeling Y. The Two Sides of the Same Coin-Influenza Virus and Intracellular Signal Transduction. Cold Spring Harb Perspect Med. 2019 Dec 23.  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Cells respond to extracellular agents by activation of intracellular signaling pathways. Viruses can be regarded as such agents, leading to a firework of signaling inside the cell, primarily induced by ...

Wu NC, Wilson IA. Influenza Hemagglutinin Structures and Antibody Recognition. Cold Spring Harb Perspect Med. 2019 Dec 23.  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Hemagglutinin (HA) is most abundant glycoprotein on the influenza virus surface. Influenza HA promotes viral entry by engaging the receptor and mediating virus-host membrane fusion. At the same time, HA ...

Wille M, Holmes EC. The Ecology and Evolution of Influenza Viruses. Cold Spring Harb Perspect Med. 2019 Dec 23.  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23 (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
The patterns and processes of influenza virus evolution are of fundamental importance, underpinning such traits as the propensity to emerge in new host species and the ability to rapidly generate antigenic ...

Wasik BR, Voorhees IEH, Parrish CR. Canine and Feline Influenza. Cold Spring Harb Perspect Med. 2019 Dec 23..  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
Influenza virus infections of carnivores-primarily in dogs and in large and small cats-have been repeatedly observed to be caused by a number of direct spillovers of avian viruses or in infections by human ...

Johnson KEE, Ghedin E. Quantifying between-Host Transmission in Influenza Virus Infections. Cold Spring Harb Perspect Med. 2019 Dec 23..  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
The error-prone replication and life cycle of influenza virus generate a diverse set of genetic variants. Transmission between hosts strictly limits both the number of virus particles and the genetic diversity ...

Schaack GA, Mehle A. Experimental Approaches to Identify Host Factors Important for Influenza Virus. Cold Spring Harb Perspect Med. 2019 Dec 23..  Full Text  
submitted by kickingbird at Dec, 26, 2019 from Cold Spring Harb Perspect Med. 2019 Dec 23. (via http://perspectivesinmedicine.cshlp.org/content/early/2019/1)
An ever-expanding toolkit of experimental methods provides the means to discover and characterize host factors important for influenza virus. Here, we describe common methods for investigating genetic ...

Gadalla MR, Abrami L, van der Goot FG, Veit M. Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20. Biochem J. 2019 Dec 24.  Abstract  
submitted by kickingbird at Dec, 26, 2019 from Biochem J. 2019 Dec 24 (via https://portlandpress.com/biochemj/article/doi/10.1042/BCJ20)
Hemagglutinin (HA), a glycoprotein of Influenza A viruses and its proton-channel M2 are site-specifically modified with fatty acids. Whereas two cysteines in the short cytoplasmic tail of HA contain only ...

Zhang Y, Wang X, Li Y, Ma J. Spatiotemporal Analysis of Influenza in China, 2005-2018. Sci Rep. 2019 Dec 23;9(1):19650..  Abstract  
submitted by kickingbird at Dec, 26, 2019 from Sci Rep. 2019 Dec 23;9(1):19650. (via https://www.nature.com/articles/s41598-019-56104-8)
Influenza is a major cause of morbidity and mortality worldwide, as well as in China. Knowledge of the spatial and temporal characteristics of influenza is important in evaluating and developing disease ...

He J, et al. Sporadic occurrence of H9N2 avian influenza infections in human in Anhui province, eastern China: A notable problem. Microb Pathog. 2019 Dec 18:103940.  Abstract  
submitted by kickingbird at Dec, 23, 2019 from Microb Pathog. 2019 Dec 18:103940 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
H9N2 viruses can cause great economic losses to the domestic poultry industry when co-infected with other influenza viruses or pathogens. . To better understand the molecular characteristics of H9N2 avian ...

Baranovskaya I, et al. Changes in RNA secondary structure affect NS1 protein expression during early stage influenza virus infection. Virol J. 2019 Dec 21;16(1):162..  Abstract  
submitted by kickingbird at Dec, 23, 2019 from Virol J. 2019 Dec 21;16(1):162. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
RNA secondary structures play a key role in splicing, gene expression, microRNA biogenesis, RNA editing, and other biological processes. The importance of RNA structures has been demonstrated in the life ...

Yao L, et al. Persistence of H7N9 virus antibody response 2 years after infection. Influenza Other Respir Viruses. 2019 Dec 19..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Influenza Other Respir Viruses. 2019 Dec 19. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12702)
We measured antibodies against H7N9 virus 2 years after infection in 14 patients who were infected during October 2016-September 2017. Approximately 2 years after infection, antibody titers ≥10 were detectable ...

Hassan KE, et al. Novel Reassortant Highly Pathogenic Avian Influenza A(H5N2) Virus in Broiler Chickens, Egypt. Emerg Infect Dis. 2020 Jan;26(1):129-133..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):129-133. (via https://wwwnc.cdc.gov/eid/article/26/1/19-0570_article)
We detected a novel reassortant highly pathogenic avian influenza A(H5N2) virus in 3 poultry farms in Egypt. The virus carried genome segments of a pigeon H9N2 influenza virus detected in 2014, a nucleoprotein ...

Chu DKW, et al. Influenza A Virus Infections in Dromedary Camels, Nigeria and Ethiopia, 2015-2017. Emerg Infect Dis. 2020 Jan;26(1):173-176.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):173-176 (via https://wwwnc.cdc.gov/eid/article/26/1/19-1165_article)
We examined nasal swabs and serum samples acquired from dromedary camels in Nigeria and Ethiopia during 2015-2017 for evidence of influenza virus infection. We detected antibodies against influenza A(H1N1) ...

Jiang W, et al. Antigenic Variant of Highly Pathogenic Avian Influenza A(H7N9) Virus, China, 2019. Emerg Infect Dis. 2020 Feb 17;26(2).  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Feb 17;26(2) (via https://wwwnc.cdc.gov/eid/article/26/2/19-1105_article)
In China, influenza A(H7N9) virus appeared in 2013, then mutated into a highly pathogenic virus, causing outbreaks among poultry and cases in humans. Since September 2017, extensive use of the corresponding ...

Murakami S, et al. Influenza D Virus of New Phylogenetic Lineage, Japan. Emerg Infect Dis. 2020 Jan;26(1):168-171..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Emerg Infect Dis. 2020 Jan;26(1):168-171. (via https://wwwnc.cdc.gov/eid/article/26/1/19-1092_article)
Influenza D virus (IDV) can potentially cause respiratory diseases in livestock. We isolated a new IDV strain from diseased cattle in Japan; this strain is phylogenetically and antigenically distinguished ...

Tepper V, et al. Influenza A/H4N2 mallard infection experiments further indicate zanamivir as less prone to induce environmental resistance development than oseltamivir. J Gen Virol. 2019 Dec 19.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from J Gen Virol. 2019 Dec 19 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Neuraminidase inhibitors (NAIs) are the gold standard treatment for influenza A virus (IAV). Oseltamivir is mostly used, followed by zanamivir (ZA). NAIs are not readily degraded in conventional wastewater ...

Jia R, Liu S, Xu J, Liang X. IL16 deficiency enhances Th1 and cytotoxic T lymphocyte response against influenza A virus infection. Biosci Trends. 2019 Dec 18.  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Biosci Trends. 2019 Dec 18 (via https://www.jstage.jst.go.jp/article/bst/advpub/0/advpub_201)
Influenza A virus (IAV) is the major cause of seasonal epidemics and flu outbreaks worldwide. Given that interleukin 16 (IL16) can regulate T cell function and is one of the signature markers for virus ...

Abolnik C, Strydom C, Rauff DL, Wandrag DBR, Petty. Continuing evolution of H6N2 influenza a virus in South African chickens and the implications for diagnosis and control. BMC Vet Res. 2019 Dec 18;15(1):455..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from BMC Vet Res. 2019 Dec 18;15(1):455. (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
BACKGROUND: The threat of poultry-origin H6 avian influenza viruses to human health emphasizes the importance of monitoring their evolution. South Africa's H6N2 epidemic in chickens began in 2001 and two ...

Mu?oz-Moreno R, et al. Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses. Cell Rep. 2019 Dec 17;29(12):3997-4009.e5..  Abstract  
submitted by kickingbird at Dec, 21, 2019 from Cell Rep. 2019 Dec 17;29(12):3997-4009.e5. (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)315)
Influenza A viruses (IAVs) have a remarkable tropism in their ability to circulate in both mammalian and avian species. The IAV NS1 protein is a multifunctional virulence factor that inhibits the type ...

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