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2025-4-1 2:24:42
Article

Yu X, Ni Z, Wang Y, Wang J, Deng G, Shi J, Kong H,. Claudin-11 plays a pivotal role in the clathrin-mediated endocytosis of influenza A virus. Sci China Life Sci. 2025 Feb 20.  Abstract  
submitted by kickingbird at Feb, 24, 2025 from Sci China Life Sci. 2025 Feb 20 (via https://link.springer.com/article/10.1007/s11427-024-2856-y)
Identification of host factors that play a key role in viral replication is of great importance for antiviral development. Metabotropic glutamate receptor subtype 2 (mGluR2) is the receptor to trigger ...

Ye Q, Xiao Z, Bai C, Yao H, Zhao L, Tan WS. Unveiling the multi-characteristic potential of hyper-productive suspension MDCK cells for advanced influenza A virus propagation. Vaccine. 2025 Feb 21;52:126900.  Abstract  
submitted by kickingbird at Feb, 24, 2025 from Vaccine. 2025 Feb 21;52:126900 (via https://pubmed.ncbi.nlm.nih.gov/39985968/)
The global population faces persistent threats from influenza viruses, with vaccination remaining the most cost-effective preventive measure against influenza. Mammalian cell-based influenza vaccine production ...

Echeverri-De la Hoz D, Martínez-Bravo C, Gastelbon. Genomics of novel influenza A virus (H18N12) in bats, Caribe Colombia. Sci Rep. 2025 Feb 22;15(1):6507.  Abstract  
submitted by kickingbird at Feb, 24, 2025 from Sci Rep. 2025 Feb 22;15(1):6507 (via https://www.nature.com/articles/s41598-025-91026-8)
Influenza viruses are highly capable of mutating and adapting in mammalian hosts. While these viruses have been extensively studied in birds, research on their presence in bats has been limited. However, ...

Karla M Castro, etc.,al. [preprint]Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity. https://doi.org/10.1101/2024.12.17.628867.  Abstract  
submitted by kickingbird at Feb, 24, 2025 from https://doi.org/10.1101/2024.12.17.628867 (via https://www.biorxiv.org/content/10.1101/2024.12.17.628867v2)
Antigenic variability among influenza virus strains poses a significant challenge to developing broadly protective, long-lasting vaccines. Current annual vaccines target specific strains, requiring accurate ...

Garazi Pena Alzua, etc.,al. [preprint]Human monoclonal antibodies that target clade 2.3.4.4b H5N1 hemagglutinin. https://doi.org/10.1101/2025.02.21.639446.  Abstract  
submitted by kickingbird at Feb, 24, 2025 from https://doi.org/10.1101/2025.02.21.639446 (via https://www.biorxiv.org/content/10.1101/2025.02.21.639446v1)
The highly pathogenic avian influenza H5N1 virus clade 2.3.4.4b has been spreading globally since 2022, causing mortality and morbidity in domestic and wild birds and mammals, including infection in humans, ...

Oona Liedes, etc.,al. [preprint]Inactivated Zoonotic Influenza A(H5N8) Vaccine Induces Robust Antibody Responses Against Recent Highly Pathogenic Avian Influenza Clade 2.3.4.4b A(H5N1) Viruses. https://doi.org/10.1101/2025.02.12.25322044.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from https://doi.org/10.1101/2025.02.12.25322044 (via https://www.medrxiv.org/content/10.1101/2025.02.12.25322044v)
In 2023, Finland faced an outbreak of highly pathogenic avian influenza caused by clade 2.3.4.4b A(H5N1) viruses, which spread from wild birds to fur farms. Vaccinations of individuals at-risk, such as ...

Gordon C. Adams, etc.,al. [preprint]Combing the haystacks: The search for highly pathogenic avian influenza virus using a combined clinical and research-developed testing strategy. https://doi.org/10.1101/2025.02.12.25321810.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from https://doi.org/10.1101/2025.02.12.25321810 (via https://www.medrxiv.org/content/10.1101/2025.02.12.25321810v)
Background Highly pathogenic H5 avian influenza A has caused sporadic human infections, increasing the risk for potential human-to-human spread. In 2024, the U.S. experienced outbreaks among poultry and ...

Branda F, Yon DK, Albanese M, Binetti E, Giovanett. Equine Influenza: Epidemiology, Pathogenesis, and Strategies for Prevention and Control. Viruses. 2025; 17(3):302.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from Viruses. 2025; 17(3):302 (via https://www.mdpi.com/1999-4915/17/3/302)
Equine influenza (EI) is a highly contagious respiratory disease caused by the equine influenza virus (EIV), posing a significant threat to equine populations worldwide. EIV exhibits considerable antigenic ...

Qila Sa, etc.,al. A programmable nucleic acid fluorescence biosensor based on the BstNI endonuclease for detection of the influenza A (H1N1) virus. Biomolecular Spectroscopy, 2025.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from Biomolecular Spectroscopy, 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S13861)
Timely and accurate diagnosis of influenza virus is essential to prevent the spread of disease and to select an appropriate treatment strategy. Here, we report the development of a novel fluorescence biosensor ...

Kumar J, Xu M, Li YA, You SW, Doherty BM, Gardiner. Capacitive Biosensor for Rapid Detection of Avian (H5N1) Influenza and E. coli in Aerosols. ACS Sens. 2025 Feb 21.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from ACS Sens. 2025 Feb 21 (via https://pubs.acs.org/doi/10.1021/acssensors.4c03087)
Airborne transmission via aerosols is a dominant route for the transmission of respiratory pathogens, including avian H5N1 influenza A virus and E. coli bacteria. Rapid and direct detection of respiratory ...

Gonzales JE 2nd, Kim I, Bastiray A, Hwang W, Cho J. Evolutionary rewiring of the dynamic network underpinning allosteric epistasis in NS1 of the influenza A virus. Proc Natl Acad Sci U S A. 2025 Feb 25;122(8):e2410.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from Proc Natl Acad Sci U S A. 2025 Feb 25;122(8):e2410 (via https://www.pnas.org/doi/10.1073/pnas.2410813122)
Viral proteins frequently mutate to evade host innate immune responses, yet the impact of these mutations on the molecular energy landscape remains unclear. Epistasis, the intramolecular communications ...

Schreiber A, Oberberg N, Ambrosy B, Rodner F, Kuma. Influenza H5Nx Viruses are susceptible to MEK1/2 Inhibition by zapnometinib. Emerg Microbes Infect. 2025 Feb 20:2471022.  Abstract  
submitted by kickingbird at Feb, 22, 2025 from Emerg Microbes Infect. 2025 Feb 20:2471022 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Highly pathogenic avian influenza A viruses (HPAIV) pose a significant threat to both animal and human health. These viruses have the potential to cause severe respiratory and systemic infections in birds ...

Zou, L., Zhang, C., Zhang, J. et al. Surveillance of H7N9 avian influenza virus in farmers’ markets in Beijing in 2019-2023. One Health Adv. 3, 3 (2025).  Abstract  
submitted by kickingbird at Feb, 21, 2025 from One Health Adv. 3, 3 (2025) (via https://link.springer.com/article/10.1186/s44280-025-00069-z)
Avian influenza viruses (AIVs) present an ongoing threat of human infections. Continuous surveillance is important for detecting new infections and verifying prevention and control measures. Swabs of the ...

Sandra Landazabal-Castillo, etc.,al. [preprint]Comparative Mutational Analysis and the Glycosylation Patterns of a Peruvian Isolated Avian Influenza a Virus H5N1: Exploring Possible Viral Spillover Events Within One Health Approach. DOI:10.20944/preprints202502.1501.v1.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from DOI:10.20944/preprints202502.1501.v1 (via https://www.preprints.org/manuscript/202502.1501/v1)
(1) Background: The emergence of H5N1 Influenza A viruses clade 2.3.3.4b since 2020, have caused the mortality of thousands of birds/mammals worldwide, through evolu-tionary changes have been associated ...

Cavicchio L, Campalto M, Carrino M, Lucchese L, Ce. Influenza in feral cat populations: insights from a study in North-East Italy. Front. Vet. Sci. 11:1439354.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Front. Vet. Sci. 11:1439354 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Influenza A virus (IAV) can cause high morbidity and mortality in domestic and wild avian species and it is able to infect mammals as well. IAV in cats is sporadic and self-limiting but the recent findings ...

Islam A, Islam M, Dutta P, Rahman MA, Al Mamun A,. Association of biosecurity and hygiene practices with avian influenza A/H5 and A/H9 virus infections in turkey farms. Front. Vet. Sci. , 14 March 2024.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Front. Vet. Sci. , 14 March 2024 (via https://www.frontiersin.org/journals/veterinary-science/arti)
High pathogenicity avian influenza (HPAI) H5N1 outbreaks pose a significant threat to the health of livestock, wildlife, and humans. Avian influenza viruses (AIVs) are enzootic in poultry in many countries, ...

R. Souillard, etc.,al. Burying poultry carcasses on farms as a disposal option in crisis situations: learnings and perspectives from a field study during an avian influenza epizootic in France. Poultry Science. Volume 104, Issue 2, February 202.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Poultry Science. Volume 104, Issue 2, February 202 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Appropriate disposal of dead farming animals is required to guarantee effective disease control while protecting the environment. In crisis situations, alternatives to rendering can be used, including ...

Paniz Hosseini, etc.,al. Qualitative studies on farm managers perception of risk from HPAIV and implementation of biosecurity measures on UK poultry farms. Preventive Veterinary Medicine, 15 Feb 2025.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Preventive Veterinary Medicine, 15 Feb 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
The epidemic of high pathogenicity avian influenza (HPAI) H5N1 in the United Kingdom and Northern Europe from 2021-2023 has dwarfed all previous incursions. This fact has driven the need to review biosecurity ...

Giovanetti M, Ali S, Slavov SN, Azarian T, Cella E. Epidemiological Transitions in Influenza Dynamics in the United States: Insights from Recent Pandemic Challenges. Microorganisms. 2025; 13(3):469.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Microorganisms. 2025; 13(3):469 (via https://www.mdpi.com/2076-2607/13/3/469)
The SARS-CoV-2 pandemic has reshaped the epidemiological landscape of respiratory diseases, with profound implications for seasonal influenza. Nonpharmaceutical interventions implemented globally during ...

Georgia McCluskey, Ann Cornish, Ian G Barr, Chuan. Laboratory biosafety risk assessment: a critical component of avian influenza preparedness. Journal of Biosafety and Biosecurity.  Abstract  
submitted by kickingbird at Feb, 21, 2025 from Journal of Biosafety and Biosecurity (via https://www.sciencedirect.com/science/article/pii/S258893382)
The evolving situation of the dairy cow H5N1 highly pathogenic avian influenza (HPAI) outbreaks (clade 2.3.4.4b) first identified in the USA in early 2024 has stimulated consideration of avian influenza ...

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