Sambala EZ, Ndwandwe DE, Imaan LM, Wiysonge CS. Evaluation of influenza surveillance systems in sub-Saharan Africa: a systematic review protocol. BMJ Open. 2019 Jan 28;9(1):e023335.. Abstract
submitted by kickingbird at Feb, 22, 2019 from BMJ Open. 2019 Jan 28;9(1):e023335. (via https://bmjopen.bmj.com/content/9/1/e023335.long)
INTRODUCTION: Influenza infrastructure systems are crucial for maintaining surveillance operations, and for mitigating and responding to the disease. The role of surveillance is to isolate and identify ...
Qiu Y, et al. Viral infection detection using metagenomics technology in six poultry farms of eastern China. PLoS One. 2019 Feb 20;14(2):e0211553. Abstract
submitted by kickingbird at Feb, 21, 2019 from PLoS One. 2019 Feb 20;14(2):e0211553 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
With rapidly increasing animal pathogen surveillance requirements, new technologies are needed for a comprehensive understanding of the roles of pathogens in the occurrence and development of animal diseases. ...
Tseng YC, et al. Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections. Proc Natl Acad Sci U S A. 2019 Feb 19. Abstract
submitted by kickingbird at Feb, 21, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 19 (via https://www.pnas.org/content/early/2019/02/12/1819197116)
Each year influenza virus infections cause hundreds of thousands of deaths worldwide and a significant level of morbidity with major economic burden. At the present time, vaccination with inactivated virus ...
Yokomichi H, et al. Incidence of hospitalisation for severe complications of influenza virus infection in Japanese patients between 2012 and 2016: a cross-sectional study using routinely collected administrative data. BMJ Open. 2019 Jan 17;9(1):e024687. Abstract
submitted by kickingbird at Feb, 21, 2019 from BMJ Open. 2019 Jan 17;9(1):e024687 (via https://bmjopen.bmj.com/content/9/1/e024687)
OBJECTIVE: To calculate the incidence of hospitalisation due to acute respiratory failure, pneumonia, acute respiratory distress syndrome (ARDS), febrile seizures and encephalitis/encephalopathy among ...
Gerlach T, Elbahesh H, Saletti G, Rimmelzwaan G. Recombinant influenza A viruses as vaccine vectors. Expert Rev Vaccines. 2019 Feb 19.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Expert Rev Vaccines. 2019 Feb 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30777467)
Various viruses, including poxviruses, adenoviruses and vesicular stomatitis virus, have been considered as vaccine vectors for the delivery of antigens of interest in the development of vaccines against ...
Smieszek T, Lazzari G, Salathé M. Assessing the Dynamics and Control of Droplet- and Aerosol-Transmitted Influenza Using an Indoor Positioning System. Sci Rep. 2019 Feb 18;9(1):2185.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Sci Rep. 2019 Feb 18;9(1):2185. (via https://www.ncbi.nlm.nih.gov/pubmed/30778136)
There is increasing evidence that aerosol transmission is a major contributor to the spread of influenza. Despite this, virtually all studies assessing the dynamics and control of influenza assume that ...
Koutsakos M, et al. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nat Immunol. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Nat Immunol. 2019 Feb 18. (via https://www.nature.com/articles/s41590-019-0320-6)
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross-protection against IAV strains, ...
Hu Y, et al. Immunogenicity and safety of a trivalent inactivated influenza vaccine produced in Shenzhen, China versus a comparator influenza vaccine: a phase IV randomized study. Hum Vaccin Immunother. 2019 Feb 19. Abstract
submitted by kickingbird at Feb, 21, 2019 from Hum Vaccin Immunother. 2019 Feb 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30779689)
Seasonal influenza causes substantial morbidity and mortality in China, which largely results from limited vaccine accessibility and poor vaccination coverage. Since 2013, Sanofi Pasteur's facilities in ...
Rüdiger D, Kupke SY, Laske T, Zmora P, Reichl U. Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Comput Biol. 2019 Feb 19;15(2):e1006819.. Abstract
submitted by kickingbird at Feb, 21, 2019 from PLoS Comput Biol. 2019 Feb 19;15(2):e1006819. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza A viruses (IAV) are commonly used to infect animal cell cultures for research purposes and vaccine production. Their replication is influenced strongly by the multiplicity of infection (MOI), ...
Ilyushina NA, Dickensheets H, Donnelly RP. A comparison of interferon gene expression induced by influenza A virus infection of human airway epithelial cells from two different donors. Virus Res. 2019 Feb 16. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virus Res. 2019 Feb 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30779949)
Influenza is an acute respiratory disease that can cause local annual epidemics and worldwide pandemics of different morbidity and mortality. Our understanding of host factors that modulate the frequency ...
Ren L, et al. Influenza A virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1α via inhibition of proteasome. Virology. 2019 Feb 11;530:51-58. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virology. 2019 Feb 11;530:51-58 (via https://www.ncbi.nlm.nih.gov/pubmed/30780125)
Virus reprogramming of host cellular function is a critical strategy for viral survival and replication. A better understanding of virus-host interaction may provide new potential avenues for the treatment ...
Roy Chowdhury I, Yeddula SGR, Kim SH. Pathogenicity and Transmissibility of North American H7 Low Pathogenic Avian Influenza Viruses in Chickens and Turkeys. Viruses. 2019 Feb 16;11(2). Abstract
submitted by kickingbird at Feb, 21, 2019 from Viruses. 2019 Feb 16;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30781528)
Low pathogenic avian influenza (LPAI) viruses can silently circulate in poultry and wild aquatic birds and potentially mutate into highly pathogenic avian influenza (HPAI) viruses. In the U.S., recent ...
Zhang T, Zhao H, Wang J, Han GZ. Wild birds do not harbor higher diversity of influenza virus internal genes than poultry. Virology. 2019 Feb 7;530:59-64. Abstract
submitted by kickingbird at Feb, 20, 2019 from Virology. 2019 Feb 7;530:59-64 (via https://www.ncbi.nlm.nih.gov/pubmed/30776509)
Avian influenza A virus (AIV) has threatened global economy and public health. Wild birds have long been thought to serve as the natural reservoir of influenza virus, and thus it is expected that wild ...
Hu Q, Gilley RP, Dube PH. House dust mite exposure attenuates influenza A infection in a mouse model of pulmonary allergic inflammation. Microb Pathog. 2019 Feb 15.. Abstract
submitted by kickingbird at Feb, 20, 2019 from Microb Pathog. 2019 Feb 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30776411)
Environmental allergens elicit complex immune responses in the lungs that can promote the development of asthma or exacerbate preexisting asthma in susceptible individuals. House dust mites are one of ...
Fu Y, et al. Infection Studies in Pigs and Porcine Airway Epithelial Cells Reveal an Evolution of A(H1N1)pdm09 Influenza A Viruses Toward Lower Virulence. J Infect Dis. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 20, 2019 from J Infect Dis. 2019 Feb 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30776304)
We analyzed the virulence of pandemic H1N1 2009 influenza A viruses in vivo and in vitro. Selected viruses isolated in 2009, 2010, 2014, and 2015 were assessed using an aerosol-mediated high-dose infection ...
Oppenheim B, et al. Assessing global preparedness for the next pandemic: development and application of an Epidemic Preparedness Index. BMJ Glob Health. 2019 Jan 29;4(1):e001157.. Abstract
submitted by kickingbird at Feb, 20, 2019 from BMJ Glob Health. 2019 Jan 29;4(1):e001157. (via https://www.ncbi.nlm.nih.gov/pubmed/30775006)
Introduction: Robust metrics for national-level preparedness are critical for assessing global resilience to epidemic and pandemic outbreaks. However, existing preparedness assessments focus primarily ...
Cao Y, et al. Global transcriptome analysis of H5N1 influenza virus-infected human cells. Hereditas. 2019 Feb 6;156:10. Abstract
submitted by kickingbird at Feb, 20, 2019 from Hereditas. 2019 Feb 6;156:10 (via https://www.ncbi.nlm.nih.gov/pubmed/30774581)
Background: Influenza A virus (IAV) belongs to the Orthomyxoviridae family. IAV causes a highly contagious respiratory disease in humans that exacts severe economic losses globally. The virus uses strategies ...
Curthoys NM, et al. Influenza Hemagglutinin Modulates Phosphatidylinositol 4,5-bisphosphate Membrane Clustering. Biophys J. 2019 Jan 25.. Abstract
submitted by kickingbird at Feb, 20, 2019 from Biophys J. 2019 Jan 25. (via https://www.ncbi.nlm.nih.gov/pubmed/30773293)
The lipid phosphatidylinositol 4,5-bisphosphate (PIP2) forms nanoscopic clusters in cell plasma membranes; however, the processes determining PIP2 mobility and thus its spatial patterns are not fully understood. ...
Naik RI, Vagi SJ, Uzicanin A, Dopson SA. Influenza-Related Communication and Community Mitigation Strategies: Results From the 2015 Pandemic Influenza Readiness Assessment. Health Promot Pract. 2019 Feb 17:. Abstract
submitted by kickingbird at Feb, 20, 2019 from Health Promot Pract. 2019 Feb 17: (via https://www.ncbi.nlm.nih.gov/pubmed/30773046)
Emergence of a novel infectious disease, such as pandemic influenza, is the one global crisis most likely to affect the greatest number of people worldwide. Because of the potentially severe and contagious ...
Dumm RE, et al. Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function. Nat Commun. 2019 Feb 15;10(1):779. Abstract
submitted by kickingbird at Feb, 19, 2019 from Nat Commun. 2019 Feb 15;10(1):779 (via https://www.ncbi.nlm.nih.gov/pubmed/30770807)
Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown however, that infection with apparently cytopathic ...
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