Villani L, D´Ambrosio F, Ricciardi R, de Wau. Seasonal influenza in children: Costs for the health system and society in Europe. Influenza Other Respir Viruses. 2022 Apr 15. Abstract
submitted by kickingbird at Apr, 17, 2022 from Influenza Other Respir Viruses. 2022 Apr 15 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12991)
Background: Pediatric influenza causes significant morbidity annually, resulting in an increased economic burden. Therefore, we aimed to summarize existing literature regarding the costs of pediatric influenza ...
Hicks JT, Edwards K, Qiu X, Kim DK, Hixson JE, Kra. Host diversity and behavior determine patterns of interspecies transmission and geographic diffusion of avian influenza A subtypes among North American wild reservoir species. PLoS Pathog. 2022 Apr 13;18(4):e1009973. Abstract
submitted by kickingbird at Apr, 14, 2022 from PLoS Pathog. 2022 Apr 13;18(4):e1009973 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Wild birds can carry avian influenza viruses (AIV), including those with pandemic or panzootic potential, long distances. Even though AIV has a broad host range, few studies account for host diversity ...
Sagong M, Lee YN, Song S, Cha RM, Lee EK, Kang YM,. Emergence of clade 184.108.40.206b novel reassortant H5N1 High Pathogenicity avian influenza virus in South Korea during late 2021. Transbound Emerg Dis. 2022 Apr 12. Abstract
submitted by kickingbird at Apr, 13, 2022 from Transbound Emerg Dis. 2022 Apr 12 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14551)
High pathogenicity H5N1 avian influenza viruses pose a threat to both animal and human health worldwide. In late 2020, outbreaks of H5 high pathogenicity avian influenza viruses belonging to clade 220.127.116.11b ...
Zeng Q, Wang J, Zhang X, Chen L, Zhou L, Kuang F,. Successful combinatorial therapy of sirolimus and neuraminidase inhibitors in a patient with highly pathogenic avian influenza A (H5N6) virus: a case report. Ann Transl Med. 2022 Mar;10(5):265.. Abstract
submitted by kickingbird at Apr, 12, 2022 from Ann Transl Med. 2022 Mar;10(5):265. (via https://atm.amegroups.com/article/view/91012/html)
Background: Highly pathogenic avian influenza A (H5N6) virus poses a continuous threat to human health since 2014. Although neuraminidase inhibitors (NAIs) are prescribed in most patients infected with ...
Bao D, Lu C, Ma T, Xu G, Mao Y, Xin L, Niu S, Wu Z. Hydrophobic Residues at the Intracellular Domain of the M2 Protein Play an Important Role in Budding and Membrane Integrity of Influenza Virus. J Virol. 2022 Apr 11:e0037322. Abstract
submitted by kickingbird at Apr, 12, 2022 from J Virol. 2022 Apr 11:e0037322 (via https://journals.asm.org/doi/10.1128/jvi.00373-22)
M2 protein of influenza virus plays an important role in virus budding, including membrane scission and vRNP packaging. Three hydrophobic amino acids (91F, 92V, and 94I) at the intracellular domain of ...
Kwon J, Youk S, Lee DH. Role of wild birds in the spread of clade 18.104.22.168e H5N6 highly pathogenic avian influenza virus into South Korea and Japan. Infect Genet Evol. 2022 Apr 5:105281. Abstract
submitted by kickingbird at Apr, 10, 2022 from Infect Genet Evol. 2022 Apr 5:105281 (via https://www.sciencedirect.com/science/article/pii/S156713482)
H5Nx highly pathogenic avian influenza viruses (HPAIVs) have caused transboundary epizootics in poultry and wild birds. In 2016, the H5N6 subtype of clade 22.214.171.124e HPAIVs caused multiple outbreaks in Asia, ...
European Food Safety Authority; European Centre fo. Avian influenza overview December 2021 - March 2022. EFSA J. 2022 Apr 4;20(4):e07289. Abstract
submitted by kickingbird at Apr, 9, 2022 from EFSA J. 2022 Apr 4;20(4):e07289 (via https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.)
Between 9 December 2021 and 15 March 2022, 2,653 highly pathogenic avian influenza (HPAI) virus detections were reported in 33 EU/EEA countries and the UK in poultry (1,030), in wild (1,489) and in captive ...
Ge J, Lin X, Guo J, Liu L, Li Z, Lan Y, Liu L, Guo. The Antibody Response Against Neuraminidase in Human Influenza A (H3N2) Virus Infections During 2018/2019 Flu Season: Focusing on the Epitopes of 329- N-Glycosylation and E344 in N2. Front Microbiol. 2022 Mar 21;13:845088. Abstract
submitted by kickingbird at Apr, 9, 2022 from Front Microbiol. 2022 Mar 21;13:845088 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8450)
Seasonal influenza A (H3N2) virus has been a concern since its first introduction in humans in 1968. Accumulating antigenic changes in viral hemagglutinin (HA), particularly recent cocirculations of multiple ...
Wang Y, Wang M, Zhang H, Zhao C, Zhang Y, He G, De. Emergence, Evolution, and Biological Characteristics of H10N4 and H10N8 Avian Influenza Viruses in Migratory Wild Birds Detected in Eastern China in 2020. Microbiol Spectr. 2022 Apr 7:e0080722. Abstract
submitted by kickingbird at Apr, 9, 2022 from Microbiol Spectr. 2022 Apr 7:e0080722 (via https://journals.asm.org/doi/10.1128/spectrum.00807-22)
H10Nx influenza viruses have caused increasing public concern due to their occasional infection of humans. However, the genesis and biological characteristics of H10 viruses in migratory wild birds are ...
Zheng L, Qi J, Wu J, Zheng M. Changes in Influenza Activity and Circulating Subtypes During the COVID-19 Outbreak in China. Front Med (Lausanne). 2022 Mar 22;9:829799. Abstract
submitted by kickingbird at Apr, 9, 2022 from Front Med (Lausanne). 2022 Mar 22;9:829799 (via https://www.frontiersin.org/articles/10.3389/fmed.2022.82979)
Background: Non-pharmaceutical interventions (NPIs) to mitigate COVID-19 can impact the circulation of influenza viruses. There is a need to describe the activity of influenza and its subtypes during the ...
Yang JR, Kuo CY, Yu IL, Kung FY, Wu FT, Lin JS, Li. Human infection with a reassortant swine-origin influenza A(H1N2)v virus in Taiwan, 2021. Virol J. 2022 Apr 7;19(1):63. Abstract
submitted by kickingbird at Apr, 9, 2022 from Virol J. 2022 Apr 7;19(1):63 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza A virus infections occur in different species, causing mild-to-severe symptoms that lead to a heavy disease burden. H1N1, H1N2 and H3N2 are major subtypes of swine influenza A viruses ...
Gu W, Shi J, Cui P, Yan C, Zhang Y, Wang C, Zhang. Novel H5N6 reassortants bearing the clade 126.96.36.199b HA gene of H5N8 virus have been detected in poultry and caused multiple human infections in China. Emerg Microbes Infect. 2022 Apr 5:1-27. Abstract
submitted by kickingbird at Apr, 6, 2022 from Emerg Microbes Infect. 2022 Apr 5:1-27 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
The globally circulating H5N8 avian influenza viruses bearing the clade 188.8.131.52b hemagglutinin (HA) gene are responsible for the loss of more than 33 million domestic poultry since January 2020. Moreover, ...
Xiong W, Tsang TK, Perera RAPM, Leung NHL, Fang VJ. Biphasic waning of hemagglutination inhibition antibody titers after influenza vaccination in children. J Infect Dis. 2022 Apr 5:jiac117. Abstract
submitted by kickingbird at Apr, 6, 2022 from J Infect Dis. 2022 Apr 5:jiac117 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
We explored the potential for a biphasic pattern in waning of antibody titers after influenza vaccination. We collected blood samples in a randomized controlled trial of influenza vaccination in children, ...
Ou J, Zheng F, Cheng J, Ye SS, Ye C, Jia K, Lu G,. Isolation and Genetic Characterization of Emerging H3N2 Canine Influenza Virus in Guangdong Province, Southern China, 2018-2021. Front Vet Sci. 2022 Mar 11;9:810855. Abstract
submitted by kickingbird at Apr, 5, 2022 from Front Vet Sci. 2022 Mar 11;9:810855 (via https://www.frontiersin.org/articles/10.3389/fvets.2022.8108)
H3N2 canine influenza virus (CIV) emerged in dogs in China or Korea around 2005 and was first reported in 2008. In 2015, H3N2 CIV was detected in the United States and caused a huge outbreak. To date, ...
Soda K, Tomioka Y, Hidaka C, Matsushita M, Usui T,. Susceptibility of common family Anatidae bird species to clade 184.108.40.206e H5N6 high pathogenicity avian influenza virus: an experimental infection study. BMC Vet Res. 2022 Apr 2;18(1):127. Abstract
submitted by kickingbird at Apr, 5, 2022 from BMC Vet Res. 2022 Apr 2;18(1):127 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: There were large outbreaks of high pathogenicity avian influenza (HPAI) caused by clade 220.127.116.11e H5N6 viruses in the winter of 2016-2017 in Japan, which caused large numbers of deaths among ...
Dhanasekaran V, Sullivan S, Edwards KM, Xie R, Khv. Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination. Nat Commun. 2022 Mar 31;13(1):1721. Abstract
submitted by kickingbird at Apr, 5, 2022 from Nat Commun. 2022 Mar 31;13(1):1721 (via https://www.nature.com/articles/s41467-022-29402-5)
Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels of morbidity, and substantial economic loss. Yet, global influenza circulation has been heavily suppressed by public ...
Liu R, Patel A, Du X, Liu H, Liu B, Wang C, Di Tan. Association between influenza vaccination, all-cause mortality and cardiovascular mortality: a protocol for a living systematic review and prospective meta-analysis. BMJ Open. 2022 Mar 31;12(3):e054171. Abstract
submitted by kickingbird at Apr, 5, 2022 from BMJ Open. 2022 Mar 31;12(3):e054171 (via https://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2021-0541)
Introduction: Influenza virus infection is known to increase the risk of cardiovascular events, especially in populations with pre-existing cardiovascular disease (CVD). Considering that influenza is vaccine ...
Sun H, Wu G, Zhang J, Wang Y, Qiu Y, Man H, Zhang. Characterization of an intracellular humanized single-chain antibody to matrix protein (M1) of H5N1 virus. PLoS One. 2022 Mar 31;17(3):e0266220. Abstract
submitted by kickingbird at Apr, 5, 2022 from PLoS One. 2022 Mar 31;17(3):e0266220 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
We developed a human intracellular antibody based on the M1 protein from avian influenza virus H5N1 (A/meerkat/Shanghai/SH-1/2012) and then characterized the properties of this antibody. The M1 protein ...
Morel J, Sedano L, Lejal N, Da Costa B, Batsché E,. The Influenza Virus RNA-Polymerase and the Host RNA-Polymerase II: RPB4 Is Targeted by a PB2 Domain That Is Involved in Viral Transcription. Viruses. 2022 Mar 3;14(3):518. Abstract
submitted by kickingbird at Mar, 29, 2022 from Viruses. 2022 Mar 3;14(3):518 (via https://www.mdpi.com/1999-4915/14/3/518)
Influenza virus transcription is catalyzed by the viral RNA-polymerase (FluPol) through a cap-snatching activity. The snatching of the cap of cellular mRNA by FluPol is preceded by its binding to the flexible ...
Javorsky A, Humbert PO, Kvansakul M. Structural Basis of the Avian Influenza NS1 Protein Interactions with the Cell Polarity Regulator Scribble. Viruses. 2022 Mar 11;14(3):583. Abstract
submitted by kickingbird at Mar, 29, 2022 from Viruses. 2022 Mar 11;14(3):583 (via https://www.mdpi.com/1999-4915/14/3/583)
Scribble is a highly conserved regulator of cell polarity, a process that enables the generation of asymmetry at the cellular and tissue level in higher organisms. Scribble acts in concert with Disc-large ...
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