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2024-11-23 8:55:22
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Nguyen HT, Chesnokov A, De La Cruz J, Pascua PNQ,. Antiviral susceptibility of clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses isolated from birds and mammals in the United States, 2022. Antiviral Res. 2023 Jul 24:105679.  Abstract  
submitted by kickingbird at Jul, 28, 2023 from Antiviral Res. 2023 Jul 24:105679 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Clade 2.3.4.4 b highly pathogenic avian influenza (HPAI) A (H5N1) viruses that are responsible for devastating outbreaks in birds and mammals pose a potential threat to public health. Here, we evaluated ...

Soda K, Tomioka Y, Usui T, Ozaki H, Ito H, Nagai Y. Susceptibility of common dabbling and diving duck species to clade 2.3.2.1 H5N1 high pathogenicity avian influenza virus: an experimental infection study. J Vet Med Sci. 2023 Jul 26.  Abstract  
submitted by kickingbird at Jul, 28, 2023 from J Vet Med Sci. 2023 Jul 26 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_23)
In the winter of 2010-2011, Japan experienced a large outbreak of infections caused by clade 2.3.2.1 H5N1 high pathogenicity avian influenza viruses (HPAIVs) in wild birds. Interestingly, many tufted ducks ...

Liang X, Zhang Z, Wang H, Lu X, Li W, Lu H, Roy A,. Early-life prophylactic antibiotic treatment disturbs the stability of the gut microbiota and increases susceptibility to H9N2 AIV in chicks. Microbiome. 2023 Jul 26;11(1):163.  Abstract  
submitted by kickingbird at Jul, 28, 2023 from Microbiome. 2023 Jul 26;11(1):163 (via https://pubmed.ncbi.nlm.nih.gov/37496083/)
Background: Antibiotics are widely used for prophylactic therapy and for improving the growth performance of chicken. The problem of bacterial drug resistance caused by antibiotic abuse has previously ...

Yin Y, Lai M, Zhou S, Chen Z, Jiang X, Wang L, Li. Effects and interaction of temperature and relative humidity on the trend of influenza prevalence: A multi-central study based on 30 provinces in mainland China from 2013 to 2018. Infect Dis Model. 2023 Jul 8;8(3):822-831.  Abstract  
submitted by kickingbird at Jul, 28, 2023 from Infect Dis Model. 2023 Jul 8;8(3):822-831 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Background: Evidence is inefficient about how meteorological factors influence the trends of influenza transmission in different regions of China.Methods: We estimated the time-varying reproduction number ...

Li H, Wu Y, Li M, Guo L, Gao Y, Wang Q, Zhang J, L. An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat Struct Mol Biol. 2023 Jul 24.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Nat Struct Mol Biol. 2023 Jul 24 (via https://www.nature.com/articles/s41594-023-01043-2)
Influenza polymerase (FluPol) transcribes viral mRNA at the beginning of the viral life cycle and initiates genome replication after viral protein synthesis. However, it remains poorly understood how FluPol ...

Shun K, Ying-Li S, Zhi-Juan L, Jian-Liang L, Feng. Stimulation of lipopolysaccharide from Pseudomonas aeruginosa following H9N2 IAV infection exacerbates inflammatory responses of alveolar macrophages and decreases virus replication. Microb Pathog. 2023 Jul 20:106254.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Microb Pathog. 2023 Jul 20:106254 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
H9N2 IAV infection contributed to P. aeruginosa coinfection, causing severe hemorrhagic pneumonia in mink. In this study, the in vitro alveolar macrophage models were developed to investigate the innate ...

Ariyama N, Pardo-Roa C, Mu?oz G, Aguayo C, ávila C. Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, Chile. Emerg Infect Dis. 2023 Jul 24;29(9)..  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Emerg Infect Dis. 2023 Jul 24;29(9). (via https://pubmed.ncbi.nlm.nih.gov/37487166/)
In December 2022, highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus emerged in Chile. We detected H5N1 virus in 93 samples and obtained 9 whole-genome sequences of strains from wild birds. ...

Malmberg JL, Miller M, Jennings-Gaines J, Allen SE. Mortality in Wild Turkey (Meleagris gallopavo) Associated with Natural Infection with H5N1 Highly Pathogenic Avian Influenza Virus (HPAIV) Subclade 2.3.4.4. J Wildl Dis. 2023 Jul 24.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from J Wildl Dis. 2023 Jul 24 (via https://pubmed.ncbi.nlm.nih.gov/37486883/)
A Eurasian strain of H5N1 highly pathogenic avian influenza virus (HPAIV) was first detected in North America in December 2021 and has since been confirmed in numerous wild and domestic avian species. ...

European Food Safety Authority, European Centre fo. Avian influenza overview April - June 2023. EFSA J. 2023 Jul 20;21(7):e08191.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from EFSA J. 2023 Jul 20;21(7):e08191 (via https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.)
Between 29 April and 23 June 2023, highly pathogenic avian influenza (HPAI) A(H5N1) virus (clade 2.3.4.4b) outbreaks were reported in domestic (98) and wild (634) birds across 25 countries in Europe. A ...

Islam A, Hossain ME, Amin E, Islam S, Islam M, Say. Epidemiology and phylodynamics of multiple clades of H5N1 circulating in domestic duck farms in different production systems in Bangladesh. Front Public Health. 2023 Jul 6;11:1168613.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Front Public Health. 2023 Jul 6;11:1168613 (via https://www.frontiersin.org/articles/10.3389/fpubh.2023.1168)
Waterfowl are considered to be natural reservoirs of the avian influenza virus (AIV). However, the dynamics of transmission and evolutionary patterns of AIV and its subtypes within duck farms in Bangladesh ...

Verdier V, Lilienthal F, Desvergez A, Gazaille V,. Severe forms of influenza infections admitted in intensive care units: Analysis of mortality factors. Influenza Other Respir Viruses. 2023 Jul 21;17(7):.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Influenza Other Respir Viruses. 2023 Jul 21;17(7): (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13168)
Background: The severe forms of influenza infection requiring intensive care unit (ICU) admission remain a medical challenge due to its high mortality. New H1N1 strains were hypothesized to increase mortality. ...

Liang W, Lv H, Chen C, Sun Y, Hui DS, Mok CKP. Lack of neutralizing antibodies against influenza A viruses in adults during the 2022/2023 winter season - a serological study using retrospective samples collected in Hong Kong. Int J Infect Dis. 2023 Jul 20:S1201-9712(23)00659-.  Abstract  
submitted by kickingbird at Jul, 23, 2023 from Int J Infect Dis. 2023 Jul 20:S1201-9712(23)00659- (via https://www.ijidonline.com/article/S1201-9712(23)00659-8/ful)
Background: Seasonal influenza infection cases decline significantly in Hong Kong since the COVID-19 pandemic has begun in 2020. This also reduced the opportunities of reinducing influenza-specific antibodies ...

Zhang J, Li Q, Zhu R, Xu S, Wang S, Shi H, Liu X. Loss of amino acids 67-76 in the neuraminidase protein under antibody selection pressure alters the tropism, transmissibility and innate immune response of H9N2 avian influenza virus in chickens. Vet Microbiol. 2023 Jul 17;284:109832.  Abstract  
submitted by kickingbird at Jul, 22, 2023 from Vet Microbiol. 2023 Jul 17;284:109832 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 virus has become the most widespread subtype of avian influenza in Chinese poultry. Although many studies have been published on this disease, the pathogenesis of the H9N2 virus remains to be fully ...

Spruit CM, Sweet IR, Maliepaard JCL, Bestebroer T,. Contemporary human H3N2 influenza a viruses require a low threshold of suitable glycan receptors for efficient infection. Glycobiology. 2023 Jul 20:cwad060.  Abstract  
submitted by kickingbird at Jul, 21, 2023 from Glycobiology. 2023 Jul 20:cwad060 (via https://academic.oup.com/glycob/advance-article/doi/10.1093/)
Recent human H3N2 influenza A viruses (IAV) have evolved to employ elongated glycans terminating in α2,6-linked sialic acid as their receptors. These glycans are displayed in low abundancies by (humanized) ...

Islam A, Amin E, Islam S, Hossain ME, Al Mamun A,. Annual trading patterns and risk factors of avian influenza A/H5 and A/H9 virus circulation in turkey birds ( Meleagris gallopavo) at live bird markets in Dhaka city, Bangladesh. Front Vet Sci. 2023 Jul 4;10:1148615.  Abstract  
submitted by kickingbird at Jul, 21, 2023 from Front Vet Sci. 2023 Jul 4;10:1148615 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1148)
The impacts of the avian influenza virus (AIV) on farmed poultry and wild birds affect human health, livelihoods, food security, and international trade. The movement patterns of turkey birds from farms ...

Liu L, Chen G, Huang S, Wen F. Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research Advances. Virulence. 2023 Dec;14(1):2235459.  Abstract  
submitted by kickingbird at Jul, 21, 2023 from Virulence. 2023 Dec;14(1):2235459 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Influenza A viruses (IAVs) pose a serious risk to both human and animal health. IAVs' receptor binding characteristics account for a major portion of their host range and tissue tropism. While the function ...

El Sahly HM, Yildirim I, Frey SE, Winokur P, Jacks. Safety and Immunogenicity of a Delayed Heterologous Avian Influenza A(H7N9) Vaccine Boost Following Different Priming Regimens: A Randomized Clinical Trial. J Infect Dis. 2023 Jul 19:jiad276.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from J Infect Dis. 2023 Jul 19:jiad276 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Influenza A (H7N9) has caused multiple disease waves with evidence of strain diversification. Optimal influenza A (H7N9) prime-boost vaccine strategies are unknown.Methods: We recruited participants ...

Liu M, Bakker AS, Narimatsu Y, van Kuppeveld FJM,. H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e230499.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from Proc Natl Acad Sci U S A. 2023 Aug;120(31):e230499 (via https://www.pnas.org/doi/10.1073/pnas.2304992120)
To become established upon zoonotic transfer, influenza A viruses (IAV) need to switch binding from "avian-type" α2-3-linked sialic acid receptors (2-3Sia) to "human-type" Siaα2-6-linked sialic acid receptors ...

Noh EB, Heo GB, Lee KN, Kang YM, An SH, Kim NY, Le. Subtype specific virus enrichement with immunomagnetic separation method followed by NGS unravels the mixture of H5 and H9 avian influenza virus. J Virol Methods. 2023 Jul 17:114773.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from J Virol Methods. 2023 Jul 17:114773 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Wild bird avian influenza virus (AIV) surveillance is important for the early detection of highly pathogenic AIVs and for providing early warnings to the poultry industry and veterinary services to implement ...

Waqas FH, Shehata M, Elgaher WAM, Lacour A, Kurmas. NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner. PLoS Pathog. 2023 Jul 17;19(7):e1011506.  Abstract  
submitted by kickingbird at Jul, 18, 2023 from PLoS Pathog. 2023 Jul 17;19(7):e1011506 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
In addition to antioxidative and anti-inflammatory properties, activators of the cytoprotective nuclear factor erythroid-2-like-2 (NRF2) signaling pathway have antiviral effects, but the underlying antiviral ...

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