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2026-6-9 11:48:11
Article

Andrey Coatrini-Soares, etc.,al. Microfluidic Electronic Tongue Made with Nanostructured Films of Proteins from Renewable Sources to Detect H5N1 Antibodies from Avian Influenza Virus. ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590.  Abstract  
submitted by kickingbird at May, 15, 2026 from ACS Appl. Nano Mater. 2026, 9, 15, 6581–6590 (via https://pubs.acs.org/doi/10.1021/acsanm.6c00138)
Avian influenza viruses, particularly the H5N1 subtype, represent a major global threat due to their high transmissibility and mortality rates. Rapid, low-cost, and reliable detection is essential for ...

Kota Matsumoto, etc.,al. Viral Membrane-Targeting Amphipathic Helical Peptide Ligands for Colorimetric Sandwich Assays of Influenza A Virus Particles. ACS Sens. 2026.  Abstract  
submitted by kickingbird at May, 15, 2026 from ACS Sens. 2026 (via https://pubs.acs.org/doi/10.1021/acssensors.6c00241)
Viral membrane-binding amphipathic helical (AH) peptides were explored as detection ligands in the sandwich-type colorimetric assay for selective detection of target influenza A virus (IAV) particles, ...

Jun Jiao, etc.,al. [preprint]G4 Eurasian avian-like H1N1 swine influenza viruses exhibit enhanced pathogenicity potential in mice and pigs. https://doi.org/10.64898/2026.05.12.724537.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.12.724537 (via https://www.biorxiv.org/content/10.64898/2026.05.12.724537v1)
Currently circulating swine influenza viruses (SIVs) mainly include H1N1, H1N2, and H3N2 subtypes. In this study, two G4 genotype Eurasian avian-like (EA) H1N1 SIVs were isolated from 556 samples collected ...

Alejandra Garcia-Glaessner, etc.,al. [preprint]Outbreak of H9N2 avian influenza viruses in lesser rhea in Peru, June-July 2025. https://doi.org/10.64898/2026.05.08.723762.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.08.723762 (via https://www.biorxiv.org/content/10.64898/2026.05.08.723762v1)
Avian influenza viruses (AIVs) are endemic in the Americas and responsible for outbreaks in both domestic and wild birds that occasionally spill over into humans. We report the first known outbreak of ...

Nathaniel Jackson, etc.,al. [preprint]A single PA-X mutation in bovine-origin H5N1 influenza virus reduces pathogenicity in mice. https://doi.org/10.64898/2026.05.09.724031.  Abstract  
submitted by kickingbird at May, 14, 2026 from https://doi.org/10.64898/2026.05.09.724031 (via https://www.biorxiv.org/content/10.64898/2026.05.09.724031v1)
Dairy cows have emerged as a reservoir for human infection with highly pathogenic avian influenza (HPAI) H5N1. At the bovine–human interface, H5N1 strains may acquire adaptive mutations that influence ...

Ort, J.T., Sobel Leonard, A., Li, S.H. et al. Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history. Nat Commun (2026).  Abstract  
submitted by kickingbird at May, 14, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-72941-4)
H5N1 highly pathogenic avian influenza viruses have spread globally and pose a pandemic risk. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime antibodies ...

Yang H, Zhang Y, Wang X, Chen T, Jia Y, Dou H, Jia. Epidemiological and Genomic Characterization of H5 Subtype Avian Influenza Viruses in Jining City, 2024–2025. Pathogens. 2026; 15(5):521.  Abstract  
submitted by kickingbird at May, 14, 2026 from Pathogens. 2026; 15(5):521 (via https://www.mdpi.com/2076-0817/15/5/521)
Objective: The aim of this study was to characterize the epidemiological features and whole-genome characteristics of H5 subtype avian influenza viruses circulating in Jining City during 2024–2025, and ...

Zhou L, Li X, Chen J, Liu Y, Zhang Y, Gong X, Meng. Screening of Low-Tumorigenic MDCK Cells for Potential Influenza Vaccine Substrates and Transcriptomic Analyses. International Journal of Molecular Sciences. 2026.  Abstract  
submitted by kickingbird at May, 14, 2026 from International Journal of Molecular Sciences. 2026 (via https://www.mdpi.com/1422-0067/27/9/3875)
Since MDCK cells are inherently tumorigenic, their safety in vaccine production has long been a concern; thus, establishing a screening method for low-tumorigenic cells is of great significance for influenza ...

Huang, J., Ma, K., Ding, S., Wang, Y., Xiong, J.,. A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. Emerging Microbes & Infections.  Abstract  
submitted by kickingbird at May, 14, 2026 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Influenza A viruses (IAVs) cause severe outbreaks with high mortality in birds and humans. A deeper understanding of cell-intrinsic defense mechanisms against influenza viruses is therefore crucial for ...

Steiner J, Mwanga M, et al. Concurrent Detection of Swine-Origin Influenza A(H1N1) Virus in Pigs and Farmer, Switzerland. Emerg Infect Dis. 2026 Jun.  Abstract  
submitted by kickingbird at May, 14, 2026 from Emerg Infect Dis. 2026 Jun (via https://wwwnc.cdc.gov/eid/article/32/6/25-1487_article)
We report zoonotic transmission of Eurasian avian-like swine influenza A(H1N1) virus from pigs to a farmer. The pigs and farmer experienced influenza-like illness. Whole-genome sequencing revealed >99.9% ...

Eszter Kovács, etc.,al. H5N1 2.3.4.4b HA E190D and Q226H mutations, picked up as minority variants in a patient, result in an inability to bind sialic acid. Virology.  Abstract  
submitted by kickingbird at May, 13, 2026 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
A human infection with clade 2.3.4.4b H5N1 influenza A virus in Canada revealed minority variants E190D and Q226H in the hemagglutinin (HA) receptor-binding site (RBS). Because mutations at positions 190 ...

Zhiyuan Liu, etc.,al. Gga-miR-449c suppresses H9N2 influenza virus replication via targeting the viral genome and suppressor of cytokine signaling 3. International Journal of Biological Macromolecules.  Abstract  
submitted by kickingbird at May, 13, 2026 from International Journal of Biological Macromolecules (via https://www.sciencedirect.com/science/article/abs/pii/S01418)
Avian influenza virus is a globally prevalent pathogen in poultry populations, causing severe economic losses to the poultry industry worldwide. In the present study, we demonstrate that miR-449c generates ...

Chen X, Zheng X, Zhang L, Cai X, Hong X, Hou S, Ma. Long noncoding RNA#61 synergizes with viral PA-X to augment pyroptosis and attenuate the virulence of highly pathogenic H5N1 influenza virus in mice. J Virol 0:e02214-25.  Abstract  
submitted by kickingbird at May, 13, 2026 from J Virol 0:e02214-25 (via https://journals.asm.org/doi/10.1128/jvi.02214-25)
Long non-coding RNAs (LncRNAs) play pivotal regulatory roles in various biological processes, notably in immune regulation and viral infection. We previously identified the broad anti-influenza activity ...

Chen Bin, etc.,al. Analysis of Avian Influenza Virus Contamination in Poultry-Related Environments in Shaanxi Province from 2020 to 2024. Chinese Journal of Epidemiology 2026, 47(03):515.  Abstract  
submitted by kickingbird at May, 13, 2026 from Chinese Journal of Epidemiology 2026, 47(03):515 (via http://chinaepi.icdc.cn/zhlxbx/ch/reader/view_abstract.aspx?)
Objective: To analyze the avian influenza virus (AIV) contamination in poultry-related environments in Shaanxi Province and provide a reference for strengthening regional avian influenza prevention and ...

Shen Y, Ma C, Zhang D, Shi W, Duan W, Li J, Zhang. Influenza Vaccine Effectiveness in School Outbreaks During a A(H3N2) Subclade K (J.2.4.1)-Dominated Season in Beijing, China, 2025-26. Int J Infect Dis. 2026 May 9:108777.  Abstract  
submitted by kickingbird at May, 13, 2026 from Int J Infect Dis. 2026 May 9:108777 (via https://www.ijidonline.com/article/S1201-9712(26)00412-1/ful)
Background: Schools are high-risk settings for influenza transmission. During the 2025-26 Northern Hemisphere season, influenza A(H3N2) subclade K (J.2.4.1) rapidly emerged and became predominant, but ...

Giacinti JA, Signore A, Torchetti M, Enrique Valde. North American perspective on the highly pathogenic avian influenza H5Nx clade 2.3.4.4b outbreak (November 2021 - March 2025). Can J Microbiol. 2026 May 11.  Abstract  
submitted by kickingbird at May, 12, 2026 from Can J Microbiol. 2026 May 11 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0275)
Influenza A (H5Nx) highly pathogenic avian influenza viruses of clade 2.3.4.4b were first detected in North America in late 2021, initiating a multi-year outbreak unprecedented in geographic extent, duration, ...

WPRO. Avian Influenza Weekly Update # 1044: 8 May 2026. WHO.  Abstract  
submitted by kickingbird at May, 11, 2026 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Nian YunPeng etc.,al. Investigation and Management of the First Human Case of Avian Influenza A(H10N3) Virus Infection in Northern China. Chinese Journal of Epidemiology 2026, 47(02):275.  Abstract  
submitted by kickingbird at May, 11, 2026 from Chinese Journal of Epidemiology 2026, 47(02):275 (via http://chinaepi.icdc.cn/zhlxbx/ch/reader/view_abstract.aspx?)
Objective: To analyze the epidemiological characteristics and field investigation findings of the first human case of H10N3 avian influenza virus infection in northern China, providing a reference for ...

Michelle Wille, etc.,al. [preprint]Migratory bird and marine mammal surveillance fails to find evidence for an HPAI H5N1 2.3.4.4b incursion into Australia in 2025. https://doi.org/10.64898/2026.05.07.722556.  Abstract  
submitted by kickingbird at May, 11, 2026 from https://doi.org/10.64898/2026.05.07.722556 (via https://www.biorxiv.org/content/10.64898/2026.05.07.722556v1)
The panzootic caused by high pathogenicity avian influenza (HPAI) H5N1 clade 2.3.4.4b has been devastating for animals, globally. Despite global spread, the virus remains absent in Oceania. Herein we report ...

Grace E. Quirk, etc.,al. [preprint]Variable transmission efficiency of mammalian origin HPAI D1.1 H5N1 strains in ferrets. https://doi.org/10.64898/2026.05.07.722809.  Abstract  
submitted by kickingbird at May, 11, 2026 from https://doi.org/10.64898/2026.05.07.722809 (via https://www.biorxiv.org/content/10.64898/2026.05.07.722809v1)
Highly pathogenic avian influenza H5N1 2.3.4.4b genotype D1.1 lineage continues to predominate in the United States wild bird population and has spilled over into dairy cattle three independent times. ...

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