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2019-5-20 13:43:24
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Carnaccini S, et al. Age-dependent pathogenesis of clade 2.3.4.4A H5N2 HPAIV in experimentally infected Broad Breasted White turkeys. Vet Microbiol. 2019 Apr;231:183-190.  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:183-190 (via https://www.sciencedirect.com/science/article/pii/S037811351)
Highly pathogenic avian influenza (HPAI) is a viral disease with devastating consequences to the poultry industry as it results in high morbidity, mortality and international trade restrictions. In the ...

Zhang X, et al. Pathogenesis of co-infections of influenza D virus and Mannheimia haemolytica in cattle. Vet Microbiol. 2019 Apr;231:246-253..  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:246-253. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Bovine respiratory disease (BRD) is economically significant, and influenza D virus (IDV) is commonly identified in cattle with BRD. Mannheimia haemolytica (MHA) is an opportunistic bacterial contributor ...

Mamerow S, et al. Double-attenuated influenza virus elicits broad protection against challenge viruses with different serotypes in swine. Vet Microbiol. 2019 Apr;231:160-168..  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:160-168. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Influenza A viruses (IAV) have caused seasonal epidemics and severe pandemics in humans. Novel pandemic strains as in 2009 may emerge from pigs, serving as perpetual virus reservoir. However, reliably ...

Parrish CR, Voorhees IEH. H3N8 and H3N2 Canine Influenza Viruses: Understanding These New Viruses in Dogs. Vet Clin North Am Small Anim Pract. 2019 Apr 4.  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Clin North Am Small Anim Pract. 2019 Apr 4 (via https://www.sciencedirect.com/science/article/pii/S019556161)
Two different influenza A viruses have infected and spread among dogs since 2000, and both have been widespread in dogs in North America. The H3N8 canine influenza virus arose in the United States as a ...

Marr LC, Tang JW, Van Mullekom J, Lakdawala SS. Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence. J R Soc Interface. 2019 Jan 31;16(150):20180298.  Abstract  
submitted by kickingbird at Apr, 9, 2019 from J R Soc Interface. 2019 Jan 31;16(150):20180298 (via https://royalsocietypublishing.org/doi/10.1098/rsif.2018.029)
Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important ...

Andronico A, et al. Highly pathogenic avian influenza H5N8 in south-west France 2016-2017: A modeling study of control strategies. Epidemics. 2019 Mar 28.  Abstract  
submitted by kickingbird at Apr, 7, 2019 from Epidemics. 2019 Mar 28 (via https://www.sciencedirect.com/science/article/pii/S175543651)
In the winter 2016-2017 the largest epidemic of highly pathogenic avian influenza (HPAI) ever recorded in the European Union spread to all 28 member states. France was hit particularly hard and reported ...

Matthew J Memoli, et al. Influenza A Reinfection in Sequential Human Challenge: Implications for Protective Immunity and ‘Universal’ Vaccine Development. Clinical Infectious Diseases, ciz281.  Abstract  
submitted by kickingbird at Apr, 7, 2019 from Clinical Infectious Diseases, ciz281 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
BackgroundIdentification of correlates of protection against human influenza A virus infection is important in development of broadly protective (“universal”) influenza vaccines. Certain assumptions underlie ...

Bo?i? B, et al. Comparative pathological findings in mute swans (Cygnus olor) naturally infected with highly pathogenic Avian influenza viruses H5N1 and H5N8 in Serbia. Vet Ital. 2019 Mar 31;55(1):95-101.  Abstract  
submitted by kickingbird at Apr, 7, 2019 from Vet Ital. 2019 Mar 31;55(1):95-101 (via http://www.izs.it/vet_italiana/2019/55_1/VetIt_1463_7919_2.p)
The aim of this study was to compare pathological lesions and viral antigen expression in the organs of mute swans (Cygnus olor) naturally infected with highly pathogenic avian influenza virus subtypes ...

Sun W, et al. Development of Influenza B Universal Vaccine Candidates using the “Mosaic” Hemagglutinin Approach. J Virol. 2019 Apr 3..  Abstract  
submitted by kickingbird at Apr, 6, 2019 from J Virol. 2019 Apr 3. (via https://jvi.asm.org/content/early/2019/03/28/JVI.00333-19)
Influenza B viruses cause seasonal epidemics and are a considerable burden to public health. However, protection by current seasonal vaccines is suboptimal due to the antigenic changes of the circulating ...

Akole A, Warner JM. Model of influenza virus acidification. PLoS ONE 14(4): e0214448..  Abstract  
submitted by kickingbird at Apr, 6, 2019 from PLoS ONE 14(4): e0214448. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Internal acidification of the influenza virus, mediated by the M2 proton channel, is a key step in its life cycle. The interior M1 protein shell dissolves at pH~5.5 to 6.0, allowing the release of vRNA ...

Ciminski K, et al. Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11. Emerg Microbes Infect. 2019;8(1):556-563..  Abstract  
submitted by kickingbird at Apr, 5, 2019 from Emerg Microbes Infect. 2019;8(1):556-563. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
The human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral ...

Mathieu C, et al. H7N6 low pathogenic avian influenza outbreak in commercial turkey farms in Chile caused by a native South American Lineage. Transbound Emerg Dis. 2019 Apr 4.  Abstract  
submitted by kickingbird at Apr, 5, 2019 from Transbound Emerg Dis. 2019 Apr 4 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13166)
In December 2016, low pathogenic avian influenza (LPAI) caused by an H7N6 subtype was confirmed in a grow-out turkey farm located in Valparaiso Region, Chile. Depopulation of exposed animals, zoning, animal ...

Altman MO, et al. Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. MBio. 2019 Apr 2;10(2)..  Abstract  
submitted by kickingbird at Apr, 5, 2019 from MBio. 2019 Apr 2;10(2). (via https://mbio.asm.org/content/10/2/e00204-19)
Human antibody-based immunity to influenza A virus is limited by antigenic drift resulting from amino acid substitutions in the hemagglutinin (HA) head domain. Glycan addition can cause large antigenic ...

Li Y, et al. Genotypic evolution and epidemiological characteristics of H9N2 influenza virus in Shandong Province, China. Poult Sci. 2019 Apr 2.  Abstract  
submitted by kickingbird at Apr, 5, 2019 from Poult Sci. 2019 Apr 2 (via https://academic.oup.com/ps/advance-article-abstract/doi/10.)
H9N2 avian influenza has been prevalent in chicken flocks of China for years. In the first half year of 2018, clinical cases of suspected H9N2 infection were collected from chicken flocks in Shandong province. ...

Sawlwin DC, Graves Jones A, Albano FR. Modification of the vaccine manufacturing process improves the pyrogenicity profile of inactivated influenza vaccines in young children. Vaccine. 2019 Mar 29. pii: S0264-410X(19)30390-1..  Abstract  
submitted by kickingbird at Apr, 4, 2019 from Vaccine. 2019 Mar 29. pii: S0264-410X(19)30390-1. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BACKGROUND: There were increased reports of fevers and febrile reactions in young children (particularly children aged METHODS: For each study, fever rates (any grade and severe) were determined for the ...

Qiu Y, et al. Characterization of three clade 2.3.4.4 H5 highly pathogenic avian influenza viruses isolated from wild birds. J Infect. 2019 Mar 27. pii: S0163-4453(19)30096-9..  Abstract  
submitted by kickingbird at Apr, 1, 2019 from J Infect. 2019 Mar 27. pii: S0163-4453(19)30096-9. (via https://www.journalofinfection.com/article/S0163-4453(19)300)
We isolated and characterized three H5 HPAIVs with different NA subtypes (N1, N6 and N8) during avian influenza virus (AIV) surveillance in wild birds during 2015-2016. The P126/H5N1, P560/H5N6 and ST/H5N8 ...

Ang LW, Cui L, Mak TM, Ng Y, Leo YS, Lee VJ. Differential age-specific distribution of influenza virus types and subtypes in tropical Singapore, 2011-2017. J Med Virol. 2019 Mar 30..  Abstract  
submitted by kickingbird at Mar, 31, 2019 from J Med Virol. 2019 Mar 30. (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25473)
Surveillance and reporting of epidemiological features of seasonal influenza mostly are aggregates across all-ages. We investigated age-specific differences in distribution of influenza virus (sub)types ...

Hsieh MS, Chang YC, He JL, Juang RH. Positive charge of Arg-201 on hemagglutinin is required for the binding of H6N1 avian influenza virus to its target through a two-step process. Virus Res. 2019 Mar 26.  Abstract  
submitted by kickingbird at Mar, 31, 2019 from Virus Res. 2019 Mar 26 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
In our previous study, we produced a monoclonal antibody EB2 that recognized an epitope in the HA1 domain on the hemagglutinin (HA) of H6N1 influenza virus (A/chicken/Taiwan/2838?V/00). The residue Arg-201 ...

Jimenez-Bluhm P, et al. Low pathogenic avian influenza (H7N6) virus causing an outbreak in commercial Turkey farms in Chile. Emerg Microbes Infect. 2019;8(1):479-485..  Abstract  
submitted by kickingbird at Mar, 31, 2019 from Emerg Microbes Infect. 2019;8(1):479-485. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
In late 2016, an H7N6 low pathogenic avian influenza virus outbreak occurred in domestic turkeys in Central Chile. We characterized the genetic and antigenic properties of the outbreak virus and its experimental ...

Honce R, Schultz-Cherry S. Influenza in obese travellers: increased risk and complications, decreased vaccine effectiveness. J Travel Med. 2019 Apr 1.  Abstract  
submitted by kickingbird at Mar, 31, 2019 from J Travel Med. 2019 Apr 1 (via https://academic.oup.com/jtm/advance-article-abstract/doi/10)
BACKGROUND: Obesity is a worldwide epidemic and was empirically shown to increase the risk of developing severe influenza virus infection. As international travel becomes more common and obesity is now ...

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