Tapia R, Brito B, Saavedra M, Mena J, García-Salum. Novel influenza A viruses in pigs with zoonotic potential, Chile. Microbiol Spectr. 2024 Mar 6:e0218123. Abstract submitted by kickingbird at Mar, 7, 2024 from Microbiol Spectr. 2024 Mar 6:e0218123 (via https://journals.asm.org/doi/10.1128/spectrum.02181-23) Novel H1N2 and H3N2 swine influenza A viruses (IAVs) have recently been identified in Chile. The objective of this study was to evaluate their zoonotic potential. We perform phylogenetic analyses to determine ... Tan M, Zhang Y, Bo H, Li X, Zou S, Yang L, Liu J,. Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice. Infect Med (Beijing). 2024 Feb 13;3(1):100090. Abstract submitted by kickingbird at Mar, 7, 2024 from Infect Med (Beijing). 2024 Feb 13;3(1):100090 (via https://www.sciencedirect.com/science/article/pii/S2772431X2) Background: Since the first human infection with H9N2 virus was reported in 1998, the number of cases of H9N2 infection has exceeded one hundred by 2021. However, there is no systematic description of ... Sanogo IN, Guinat C, Dellicour S, Diakité MA, Nian. Genetic insights of H9N2 avian influenza viruses circulating in Mali and phylogeographic patterns in Northern and Western Africa. Virus Evol. 2024 Feb 19;10(1):veae011. Abstract submitted by kickingbird at Mar, 6, 2024 from Virus Evol. 2024 Feb 19;10(1):veae011 (via https://academic.oup.com/ve/article/10/1/veae011/7610485) Avian influenza viruses (AIVs) of the H9N2 subtype have become widespread in Western Africa since their first detection in 2017 in Burkina Faso. However, the genetic characteristics and diffusion patterns ... Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z,. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet. 2024 Feb 29. Abstract submitted by kickingbird at Mar, 3, 2024 from Nat Genet. 2024 Feb 29 (via https://www.nature.com/articles/s41588-024-01668-z) Humans display remarkable interindividual variation in their immune response to identical challenges. Yet, our understanding of the genetic and epigenetic factors contributing to such variation remains ... Frutos AM, Price AM, Harker E, Reeves EL, Ahmad HM. Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States. MMWR Morb Mortal Wkly Rep. 2024 Feb 29;73(8):168-1. Abstract submitted by kickingbird at Mar, 1, 2024 from MMWR Morb Mortal Wkly Rep. 2024 Feb 29;73(8):168-1 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7308a3.htm?s_cid=mm) In the United States, annual influenza vaccination is recommended for all persons aged ≥6 months. Using data from four vaccine effectiveness (VE) networks during the 2023-24 influenza season, interim influenza ... Monjane IVA, Djedje H, Tamele E, Nhabomba V, Tivan. H7N6 highly pathogenic avian influenza in Mozambique, 2023. Emerg Microbes Infect. 2024 Dec;13(1):2321993. Abstract submitted by kickingbird at Mar, 1, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2321993 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2) On 13 October 2023, the National Directorate for Livestock Development in Mozambique was notified of a suspected outbreak of avian influenza in commercial layers. Samples were screened by real-time and ... Ding X, Liu J, Jiang T, Wu A. Transmission restriction and genomic evolution co-shape the genetic diversity patterns of influenza A virus. Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7. Abstract submitted by kickingbird at Mar, 1, 2024 from Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7 (via https://www.sciencedirect.com/science/article/pii/S1995820X2) Influenza A virus (IAV) shows an extensive host range and rapid genomic variations, leading to continuous emergence of novel viruses with significant antigenic variations and the potential for cross-species ... Zhang M, Liu M, Chen H, Qiu T, Jin X, Fu W, Teng Q. PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A. J Virol. 2024 Feb 29:e0194423. Abstract submitted by kickingbird at Mar, 1, 2024 from J Virol. 2024 Feb 29:e0194423 (via https://journals.asm.org/doi/10.1128/jvi.01944-23) Since the first human infection reported in 2013, H7N9 avian influenza virus (AIV) has been regarded as a serious threat to human health. In this study, we sought to identify the virulence determinant ... Yang R, Pan M, Guo J, Huang Y, Zhang QC, Deng T, W. Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replication. Cell Rep. 2024 Feb 27;43(3):113833. Abstract submitted by kickingbird at Feb, 29, 2024 from Cell Rep. 2024 Feb 27;43(3):113833 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)001) Influenza A virus (IAV) represents a constant public health threat. The single-stranded, segmented RNA genome of IAV is replicated in host cell nuclei as a series of 8 ribonucleoprotein complexes (vRNPs) ... Han J, Chang W, Fang J, Hou X, Li Z, Wang J, Deng. The H9N2 avian influenza virus increases APEC adhesion to oviduct epithelia by viral NS1 protein-mediated activation of the TGF-β pathway. J Virol. 2024 Feb 28:e0151223. Abstract submitted by kickingbird at Feb, 29, 2024 from J Virol. 2024 Feb 28:e0151223 (via https://journals.asm.org/doi/10.1128/jvi.01512-23) Avian influenza A (H9N2) avian influenza is a low-pathogenic avian influenza circulating in poultry and wild birds worldwide and frequently contributes to chicken salpingitis that is caused by avian pathogenic ... Cardenas-Garcia S, Cáceres CJ, Jain A, Geiger G, M. Impact of sex on humoral immunity with live influenza B virus vaccines in mice. NPJ Vaccines. 2024 Feb 26;9(1):45. Abstract submitted by kickingbird at Feb, 28, 2024 from NPJ Vaccines. 2024 Feb 26;9(1):45 (via https://www.nature.com/articles/s41541-024-00827-x) Influenza B virus (FLUBV) poses a significant infectious threat, with frequent vaccine mismatch limiting its effectiveness. Our previous work investigated the safety and efficacy of modified live attenuated ... de Bruin ACM, Spronken MI, Kok A, Rosu ME, de Meul. Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks. PLoS Pathog. 2024 Feb 26;20(2):e1011942. Abstract submitted by kickingbird at Feb, 27, 2024 from PLoS Pathog. 2024 Feb 26;20(2):e1011942 (via https://journals.plos.org/plospathogens/article?id=10.1371/j) Highly pathogenic avian influenza viruses (HPAIVs) cause severe hemorrhagic disease in terrestrial poultry and are a threat to the poultry industry, wild life, and human health. HPAIVs arise from low pathogenic ... Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, M. Characterization of a human H3N8 influenza virus. EBioMedicine. 2024 Feb 25;101:105034. Abstract submitted by kickingbird at Feb, 27, 2024 from EBioMedicine. 2024 Feb 25;101:105034 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39) Background: In 2022 and 2023, novel reassortant H3N8 influenza viruses infected three people, marking the first human infections with viruses of this subtype.Methods: Here, we generated one of these viruses ... Rose AMC, Pozo F, Martínez-Baz I, Mazagatos C, Bos. Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network. Influenza Other Respir Viruses. 2024 Feb;18(2):e13. Abstract submitted by kickingbird at Feb, 27, 2024 from Influenza Other Respir Viruses. 2024 Feb;18(2):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13255) We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection ... Wibawa H, Wibowo PE, Supriyadi A, Lestari L, Silab. Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022. Emerg Infect Dis. 2024 Mar;30(3):586-590. Abstract submitted by kickingbird at Feb, 27, 2024 from Emerg Infect Dis. 2024 Mar;30(3):586-590 (via https://wwwnc.cdc.gov/eid/article/30/3/23-0973_article) Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected ... Plaza PI, Gamarra-Toledo V, Euguí JR, Lambertucci. Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide. Emerg Infect Dis. 2024 Mar;30(3):444-452. Abstract submitted by kickingbird at Feb, 27, 2024 from Emerg Infect Dis. 2024 Mar;30(3):444-452 (via https://wwwnc.cdc.gov/eid/article/30/3/23-1098_article) We reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). ... Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, O. Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome. Nucleic Acids Res. 2024 Feb 26:gkae133. Abstract submitted by kickingbird at Feb, 27, 2024 from Nucleic Acids Res. 2024 Feb 26:gkae133 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar) Productive infections by RNA viruses require faithful replication of the entire genome. Yet many RNA viruses also produce deletion-containing viral genomes (DelVGs), aberrant replication products with ... Yang RS, Traver M, Barefoot N, Stephens T, Alabanz. Mosaic quadrivalent influenza vaccine single nanoparticle characterization. Sci Rep. 2024 Feb 24;14(1):4534. Abstract submitted by kickingbird at Feb, 26, 2024 from Sci Rep. 2024 Feb 24;14(1):4534 (via https://www.nature.com/articles/s41598-024-54876-2) Recent work by our laboratory and others indicates that co-display of multiple antigens on protein-based nanoparticles may be key to induce cross-reactive antibodies that provide broad protection against ... Murphy C, Kwan MYW, Chan ELY, Wong JSC, Sullivan S. Influenza vaccine effectiveness against hospitalizations associated with influenza A(H3N2) in Hong Kong children aged 9 months to 17 years, June-November 2023. Vaccine. 2024 Feb 22:S0264-410X(24)00215-9. Abstract submitted by kickingbird at Feb, 25, 2024 from Vaccine. 2024 Feb 22:S0264-410X(24)00215-9 (via https://www.sciencedirect.com/science/article/abs/pii/S02644) A test negative study was carried out from 13 June through to 15 November 2023 enrolling 3183 children hospitalized with acute respiratory illness in Hong Kong. Influenza A and B viruses were detected ... Ricci I, Tofani S, Lelli D, Vincifori G, Rosone F,. First Reported Circulation of Equine Influenza H3N8 Florida Clade 1 Virus in Horses in Italy. Animals (Basel). 2024 Feb 12;14(4):598. Abstract submitted by kickingbird at Feb, 25, 2024 from Animals (Basel). 2024 Feb 12;14(4):598 (via https://www.mdpi.com/2076-2615/14/4/598) Background: Equine influenza (EI) is a highly contagious viral disease of equids characterized by pyrexia and respiratory signs. 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