Okuya K, Mine J, Tokorozaki K, Kojima I, Esaki M,. Genetically Diverse Highly Pathogenic Avian Influenza A(H5N1/H5N8) Viruses among Wild Waterfowl and Domestic Poultry, Japan, 2021. Emerg Infect Dis. 2022 May 24;28(7). Abstract
submitted by kickingbird at May, 26, 2022 from Emerg Infect Dis. 2022 May 24;28(7) (via https://pubmed.ncbi.nlm.nih.gov/35609620/)
Genetic analyses of highly pathogenic avian influenza H5 subtype viruses isolated from the Izumi Plain, Japan, revealed cocirculation of 2 genetic groups of clade 184.108.40.206b viruses among migratory waterfowl. ...
Peters M, King J, Wohlsein P, Grund C, Harder T. Genuine lethal infection of a wood pigeon (Columba palumbus) with high pathogenicity avian influenza H5N1, clade 220.127.116.11b, in Germany, 2022. Vet Microbiol. 2022 May 13;270:109461. Abstract
submitted by kickingbird at May, 24, 2022 from Vet Microbiol. 2022 May 13;270:109461 (via https://pubmed.ncbi.nlm.nih.gov/35594637/)
Despite the increasing frequency of avian influenza (AI) cases in wild birds in Europe during the last decade, doves and pigeons were not recognized to be part of the AI epidemiology. Here we describe ...
Krischuns T, Isel C, Drncova P, Lukarska M, Pflug. Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. PLoS Pathog. 2022 May 23;18(5):e1010328. Abstract
submitted by kickingbird at May, 24, 2022 from PLoS Pathog. 2022 May 23;18(5):e1010328 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During annual influenza epidemics, influenza B viruses (IBVs) co-circulate with influenza A viruses (IAVs), can become predominant and cause severe morbidity and mortality. Phylogenetic analyses suggest ...
Zheng H, Ma L, Gui R, Lin X, Ke X, Jian X, Ye C, C. G Protein Subunit β1 Facilitates Influenza A Virus Replication by Promoting the Nuclear Import of PB2. J Virol. 2022 May 23:e0049422. Abstract
submitted by kickingbird at May, 24, 2022 from J Virol. 2022 May 23:e0049422 (via https://journals.asm.org/doi/10.1128/jvi.00494-22)
G protein subunit β1 (GNB1), the beta subunit of the G protein family, plays an important role in regulating transmembrane signal transduction. Although a recent study has demonstrated that GNB1 can bind ...
H Zhang et al. Evidence for Water-borne Transmission of Highly Pathogenic Avian Influenza H5N1 viruses. Front Microbiol. 2022 provisionally accepted. Abstract
submitted by kickingbird at May, 23, 2022 from Front Microbiol. 2022 provisionally accepted (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8964)
In this study, we isolated 10 H5N1 strains from water samples in Dongting lake and 4 H5N1 strains from lakeside backyard poultry. These isolates belonged to 3 distinct clades (clade 2.3.2, 2.3.4 and 7). ...
Liu Y, Lin S, Xie Y, Zhao L, Du H, Yang S, Yin B,. ILDR1 promotes influenza A virus replication through binding to PLSCR1. Sci Rep. 2022 May 20;12(1):8515. Abstract
submitted by kickingbird at May, 23, 2022 from Sci Rep. 2022 May 20;12(1):8515 (via https://www.nature.com/articles/s41598-022-12598-3)
As a natural antiviral regulator, phospholipid scramblase 1 (PLSCR1) has been shown to inhibit influenza virus replication in infected cells through interacting with NP of influenza A virus (IAV). But ...
Hill NJ, Bishop MA, Trov?o NS, Ineson KM, Schaefer. Ecological divergence of wild birds drives avian influenza spillover and global spread. PLoS Pathog. 2022 May 19;18(5):e1010062. Abstract
submitted by kickingbird at May, 22, 2022 from PLoS Pathog. 2022 May 19;18(5):e1010062 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The diversity of influenza A viruses (IAV) is primarily hosted by two highly divergent avian orders: Anseriformes (ducks, swans and geese) and Charadriiformes (gulls, terns and shorebirds). Studies of ...
Zhang G, Xu L, Zhang J, Fang Q, Zeng J, Liu Y, Ke. A H9N2 Human Case and Surveillance of Avian Influenza Viruses in Live Poultry Markets - Huizhou City, Guangdong Province, China, 2021. China CDC Wkly. 2022 Jan 7;4(1):8-10. Abstract
submitted by kickingbird at May, 22, 2022 from China CDC Wkly. 2022 Jan 7;4(1):8-10 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2021)
What is already known about this topic?: An increasing number of human infected avian influenza A (H9N2) cases have been reported. In 2021, 11 human infections with influenza A virus subtype H9N2 (A/H9N2) ...
Su K, Yu Z, Lan Y, Wang J, Chen S, Qi L, Chen Y, T. Three Cases Infected with Avian Influenza A(H5N6) Virus - Chongqing Municipality, China, January-September, 2021. China CDC Wkly. 2022 Jan 7;4(1):11-16. Abstract
submitted by kickingbird at May, 22, 2022 from China CDC Wkly. 2022 Jan 7;4(1):11-16 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2021)
What is already known about this topic?: The World Health Organization (WHO) has reported a total of 48 cases by October 15, 2021. The continuous genomic reassortments of H5N6 and other subtype avian influenza ...
Yang F, Zhu L, Liu F, Cheng L, Yao H, Wu N, Wu H,. Generation and characterization of monoclonal antibodies against the hemagglutinin of H3N2 influenza A viruses. Virus Res. 2022 May 17:198815. Abstract
submitted by kickingbird at May, 22, 2022 from Virus Res. 2022 May 17:198815 (via https://www.sciencedirect.com/science/article/abs/pii/S01681)
Seasonal influenza viruses are highly contagious, leading to 290,000-650,000 mortalities every year globally. Among the influenza viruses, influenza A virus (H3N2) has attracted much attention due to its ...
Zhao C, Guo J, Zeng X, Shi J, Deng G, Zhang Y, Wan. Novel H7N7 avian influenza viruses detected in migratory wild birds in eastern China between 2018 and 2020. Microbes Infect. 2022 May 14:105013. Abstract
submitted by kickingbird at May, 19, 2022 from Microbes Infect. 2022 May 14:105013 (via https://www.sciencedirect.com/science/article/pii/S128645792)
Wild birds are the natural reservoirs of avian influenza viruses, and surveillance and assessment of these viruses in wild birds provide valuable information for early warning and control of animal diseases. ...
?mietanka K, ?wi?toń E, Wyrostek K, Kozak E, Taras. Highly Pathogenic Avian Influenza H5Nx in Poland in 2020/2021: a Descriptive Epidemiological Study of a Large-scale Epidemic. J Vet Res. 2022 Mar 25;66(1):1-7. Abstract
submitted by kickingbird at May, 19, 2022 from J Vet Res. 2022 Mar 25;66(1):1-7 (via https://www.sciendo.com/article/10.2478/jvetres-2022-0017)
Introduction: Highly pathogenic avian influenza (HPAI) outbreaks caused by the Gs/Gd lineage of H5Nx viruses occur in Poland with increased frequency. The article provides an update on the HPAI situation ...
Wang Q, Wang J, Xu Y, Li Z, Wang B, Li Y. The Interaction of Influenza A NS1 and Cellular TRBP Protein Modulates the Function of RNA Interference Machinery. Front Microbiol. 2022 Apr 26;13:859420. Abstract
submitted by kickingbird at May, 18, 2022 from Front Microbiol. 2022 Apr 26;13:859420 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087287/)
Influenza A virus (IAV), one of the most prevalent respiratory diseases, causes pandemics around the world. The multifunctional non-structural protein 1 (NS1) of IAV is a viral antagonist that suppresses ...
Schaaf KR, Buggs CJ, Putz ND, Langouet-Astrie CJ,. Influenza A Virus Causes Shedding of the Alveolar Epithelial Glycocalyx through Activation of Sheddases. FASEB J. 2022 May;36 Suppl 1. Abstract
submitted by kickingbird at May, 18, 2022 from FASEB J. 2022 May;36 Suppl 1 (via https://faseb.onlinelibrary.wiley.com/doi/10.1096/fasebj.202)
Objective: The healthy alveolar epithelium is protected by a heparan sulfate rich, glycosaminoglycan layer called the epithelial glycocalyx. Our group found that the epithelial glycocalyx is shed in patients ...
LE KT, Isoda N, Nguyen LT, Chu DH, Nguyen LV, Phan. Risk profile of low pathogenicity avian influenza virus infections in farms in southern Vietnam. J Vet Med Sci. 2022 May 13. Abstract
submitted by kickingbird at May, 18, 2022 from J Vet Med Sci. 2022 May 13 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_22)
The impact of low pathogenicity avian influenza (LPAI) has been confirmed mainly in farms. Unlike apparent losses caused by the high pathogenicity avian influenza (HPAI), the LPAI impact has been hardly ...
Zhu F, Teng Z, Zhou X, Xu R, Bing X, Shi L, Guo N,. H1N1 Influenza Virus-Infected Nasal Mucosal Epithelial Progenitor Cells Promote Dendritic Cell Recruitment and Maturation. Front Immunol. 2022 Apr 28;13:879575. Abstract
submitted by kickingbird at May, 18, 2022 from Front Immunol. 2022 Apr 28;13:879575 (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.8795)
The barrier function of nasal mucosal epithelial cells plays an irreplaceable role in the spread and expansion of viruses in the body. This study found that influenza A virus H1N1 could induce apoptosis ...
Cheng D, Dong Y, Wen S, Shi C. A child with acute respiratory distress syndrome caused by avian influenza H3N8 virus. J Infect. 2022 May 13:S0163-4453(22)00288-2. Abstract
submitted by kickingbird at May, 18, 2022 from J Infect. 2022 May 13:S0163-4453(22)00288-2 (via https://www.journalofinfection.com/article/S0163-4453(22)002)
?This is the first case of human infection with H3N8 virus.?The clearance time of H3N8 virus in human lungs is prolonged.?After the H3N8 virus infect the human body, they can cause severe interstitial ...
Vandoorn E, Stadejek W, Parys A, Chepkwony S, Chie. Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs. J Virol. 2022 May 12:e0051922. Abstract
submitted by kickingbird at May, 15, 2022 from J Virol. 2022 May 12:e0051922 (via https://journals.asm.org/doi/10.1128/jvi.00519-22)
Virus strains in the live attenuated influenza vaccine (LAIV) for swine in the United States that was on the market until 2020 encode a truncated nonstructural protein 1 of 126 amino acids (NS1del126). ...
Dou YC, Li YQ. Influenza A H3N2-Associated Meningoencephalitis in an Older Adult With Viral RNA in Cerebrospinal Fluid: Case Report. Front Neurol. 2022 Apr 25;13:874078. Abstract
submitted by kickingbird at May, 15, 2022 from Front Neurol. 2022 Apr 25;13:874078 (via https://www.frontiersin.org/articles/10.3389/fneur.2022.8740)
Influenza-associated encephalopathy (IAE) is most frequently observed in young children, but less reported in adults. Diagnosis of IAE is difficult, as clinical presentations vary significantly and the ...
Kenney AD, Aron SL, Gilbert C, Kumar N, Chen P, Ed. Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis. Sci Adv. 2022 May 13;8(19):eabm5371. Abstract
submitted by kickingbird at May, 15, 2022 from Sci Adv. 2022 May 13;8(19):eabm5371 (via https://www.science.org/doi/10.1126/sciadv.abm5371)
Cardiac dysfunction is a common complication of severe influenza virus infection, but whether this occurs due to direct infection of cardiac tissue or indirectly through systemic lung inflammation remains ...
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