Sautto GA, Ross TM. Hemagglutinin consensus-based prophylactic approaches to overcome influenza virus diversity. Vet Ital. 2019 Sep 30;55(3):195-201.. Abstract
submitted by kickingbird at Oct, 12, 2019 from Vet Ital. 2019 Sep 30;55(3):195-201. (via http://www.izs.it/vet_italiana/2019/55_3/VetIt_1944_10352_1.)
Each year millions of people are infected by influenza viruses, and this causes a substantial economic and health burden on our society. Influenza epidemics and pandemics are attributable to the ongoing ...
Kamiki H, et al. Adaptation of H3N2 canine influenza virus to feline cell culture. PLoS One. 2019 Oct 10;14(10):e0223507.. Abstract
submitted by kickingbird at Oct, 12, 2019 from PLoS One. 2019 Oct 10;14(10):e0223507. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
H3N2 canine influenza viruses are prevalent in Asian and North American countries. During circulation of the viruses in dogs, these viruses are occasionally transmitted to cats. If this canine virus causes ...
Nagant C, et al. Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease. PLoS One. 2019 Oct 10;14(10):e0223991. Abstract
submitted by kickingbird at Oct, 12, 2019 from PLoS One. 2019 Oct 10;14(10):e0223991 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
INTRODUCTION: Patients suffering from Sickle Cell Disease (SCD) are at increased risk for complications due to influenza virus. Annual influenza vaccination is strongly recommended but few clinical studies ...
Kode SS, Pawar SD, Tare DS, Keng SS, Mullick J. Amantadine resistance markers among low pathogenic avian influenza H9N2 viruses isolated from poultry in India, during 2009~2017. Microb Pathog. 2019 Oct 7:103779. Abstract
submitted by kickingbird at Oct, 12, 2019 from Microb Pathog. 2019 Oct 7:103779 (via https://www.sciencedirect.com/science/article/pii/S088240101)
Antiviral susceptibility screening of avian influenza (AI) H9N2 viruses is crucial considering their role at the animal-human interface and potential to cause human infections. The Matrix 2 (M2) inhibitors ...
Fujimoto Y, Inoue H, Ozawa M, Matsuu A. Serological survey of influenza A virus infection in Japanese wild boars (Sus scrofa leucomystax). Microbiol Immunol. 2019 Oct 9.. Abstract
submitted by kickingbird at Oct, 11, 2019 from Microbiol Immunol. 2019 Oct 9. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/1348-0421.12)
We conducted a serological survey to detect antibodies against influenza A virus (IAV) in Japanese wild boars in Kagoshima prefecture, Japan, between 2014 and 2017. Sero-prevalence against a pandemic-like ...
Nishioka K, Daidoji T, Nakaya T. Demethylation around the transcriptional start site of the IFN-β gene induces IFN-β production and protection against influenza virus infection. Biochem Biophys Res Commun. 2019 Oct 5.. Abstract
submitted by kickingbird at Oct, 11, 2019 from Biochem Biophys Res Commun. 2019 Oct 5. (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Seasonal influenza is related to lifestyle-associated risk factors and it has been suggested that the epigenetic state of the individual plays an important role in the severity of infection. It is well ...
Fallah Mehrabadi MH, et al. Prevalence of Avian Influenza in Live Bird Markets, Bird Gardens, and Zoos in Iran in 2015: A Cross-sectional Study. Arch Razi Inst. 2019 Sep;74(3):243-250. Abstract
submitted by kickingbird at Oct, 11, 2019 from Arch Razi Inst. 2019 Sep;74(3):243-250 (via http://archrazi.areeo.ac.ir/article_119274.html)
Avian Influenza (AI) H9N2 is endemic in Iran; therefore, it is necessary to estimate the disease prevalence among birds in live bird markets (LBMs) and assess the risk spread across the country. Accordingly, ...
Yang L, et al. Tandem mass tag-based quantitative proteomic analysis of lycorine treatment in highly pathogenic avian influenza H5N1 virus infection. PeerJ. 2019 Oct 2;7:e7697.. Abstract
submitted by kickingbird at Oct, 11, 2019 from PeerJ. 2019 Oct 2;7:e7697. (via https://peerj.com/articles/7697/)
Highly pathogenic H5N1 influenza viruses (HPAIV) cause rapid systemic illness and death in susceptible animals, leading to a disease with high morbidity and mortality rates. Although vaccines and drugs ...
Buffin S, et al. Influenza A and B virus-like particles produced in mammalian cells are highly immunogenic and induce functional antibodies. Vaccine. 2019 Oct 4.. Abstract
submitted by kickingbird at Oct, 11, 2019 from Vaccine. 2019 Oct 4. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
Influenza virus-like particles (VLPs) represent an attractive alternative to traditional influenza vaccine formulations. Influenza VLPs mimic the natural virus while lacking the genetic material, are easily ...
Chastagner A, et al. Virus persistence in pig herds led to successive reassortment events between swine and human influenza A viruses, resulting in the emergence of a novel triple-reassortant swine influenza virus. Vet Res. 2019 Oct 7;50(1):77. Abstract
submitted by kickingbird at Oct, 11, 2019 from Vet Res. 2019 Oct 7;50(1):77 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
This report describes the detection of a triple reassortant swine influenza A virus of H1avN2 subtype. It evolved from an avian-like swine H1avN1 that first acquired the N2 segment from a seasonal H3N2, ...
Butler J, et al. Insights into the Acquisition of Virulence of Avian Influenza Viruses during a Single Passage in Ferrets. Viruses. 2019 Oct 4;11(10). Abstract
submitted by kickingbird at Oct, 11, 2019 from Viruses. 2019 Oct 4;11(10) (via https://www.mdpi.com/1999-4915/11/10/915)
Circulating avian influenza viruses pose a significant threat, with human infections occurring infrequently but with potentially severe consequences. To examine the dynamics and locale of the adaptation ...
Buthelezi NM, et al. Exploring the impact of H5N1 neuraminidase (H274Y) mutation on Peramivir: A bio-computational study from a molecular perspective. J Biomol Struct Dyn. 2019 Oct 6:1-11.. Abstract
submitted by kickingbird at Oct, 9, 2019 from J Biomol Struct Dyn. 2019 Oct 6:1-11. (via https://www.tandfonline.com/doi/abs/10.1080/07391102.2019.16)
List of Abbreviations ARDS Acute Respiratory Distress Syndrome HA Haemagglutinin GAFF General Amber force field MD Molecular Dynamic NA Neuraminidase NAI Neuraminidase Inhibitor PCA Principal Component ...
Soda K, Sakita M, Usui T, Ito H, Ito T. H5N8 avian influenza virus acquires enhanced pathogenicity after a single passage in chicken. Vet Microbiol. 2019 Oct;237:108381. Abstract
submitted by kickingbird at Oct, 7, 2019 from Vet Microbiol. 2019 Oct;237:108381 (via https://www.sciencedirect.com/science/article/pii/S037811351)
The H5N8 highly pathogenic avian influenza viruses (HPAIVs) isolated in Japan during the 2014-2015 winter differed in their pathogenicity in chickens. In the present study, we examined the possibility ...
Cantan B, Luyt CE, Martin-Loeches I. Influenza Infections and Emergent Viral Infections in Intensive Care Unit. Semin Respir Crit Care Med. 2019 Aug;40(4):488-497. Abstract
submitted by kickingbird at Oct, 7, 2019 from Semin Respir Crit Care Med. 2019 Aug;40(4):488-497 (via https://www.thieme-connect.de/products/ejournals/abstract/10)
Critically ill patients are admitted to an intensive care unit (ICU) for multiple reasons. In this study, we aim to analyze the current evidence and findings associated with influenza and other emergent ...
Huang S, et al. Macrophage PPAR-γ suppresses long-term lung fibrotic sequelae following acute influenza infection. PLoS One. 2019 Oct 4;14(10):e0223430.. Abstract
submitted by kickingbird at Oct, 6, 2019 from PLoS One. 2019 Oct 4;14(10):e0223430. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Influenza virus causes a heterogeneous respiratory infectious disease ranging from self-limiting symptoms to non-resolving pathology in the lungs. Worldwide, seasonal influenza infections claim ~500,000 ...
Park YH, et al. Host-specific restriction of avian influenza virus caused by differential dynamics of ANP32 family members. J Infect Dis. 2019 Oct 3.. Abstract
submitted by kickingbird at Oct, 5, 2019 from J Infect Dis. 2019 Oct 3. (via https://academic.oup.com/jid/article-abstract/doi/10.1093/in)
Influenza viruses must utilize host factors to complete their lifecycle. Species-specific differences in host factors between birds and mammals mean that avian influenza viruses (AIVs) replicate well in ...
Chen KY, et al. Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer. PLoS Pathog. 2019 Oct 3;15(10). Abstract
submitted by kickingbird at Oct, 5, 2019 from PLoS Pathog. 2019 Oct 3;15(10) (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The influenza A virus RNA-dependent RNA polymerase complex consists in three subunits, PB2, PB1 and PA, that perform transcription and replication of the viral genome through very distinct mechanisms. ...
Sun J, et al. Novel H5N6 Avian Influenza Virus Reassortants with European H5N8 Isolated in Migratory Birds, China. Transbound Emerg Dis. 2019 Oct 3. Abstract
submitted by kickingbird at Oct, 5, 2019 from Transbound Emerg Dis. 2019 Oct 3 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13380)
Five novel H5N6 influenza viruses, including four highly pathogenic avian influenza viruses and one low pathogenic avian influenza virus, were isolated from migratory birds in Ningxia, China in November ...
Gao J, Pasion J, Sanchez-Petitto G, Law J. Influenza virus B-associated hemophagocytic lymphohistiocytosis. Hematol Rep. 2019 Sep 18;11(3):8268.. Abstract
submitted by kickingbird at Oct, 5, 2019 from Hematol Rep. 2019 Sep 18;11(3):8268. (via https://www.pagepress.org/journals/index.php/hr/article/view)
This original report describes the diagnosis and management of a male with hemophagocytic lymphohistiocytosis (HLH) triggered by influenza B virus infection. The patient was diagnosed with HLH- 2004 clinical ...
Popova AV, et al. Allele-specific nonstationarity in evolution of influenza A virus surface proteins. Proc Natl Acad Sci U S A. 2019 Oct 2.. Abstract
submitted by kickingbird at Oct, 5, 2019 from Proc Natl Acad Sci U S A. 2019 Oct 2. (via https://www.pnas.org/content/early/2019/10/01/1904246116)
Influenza A virus (IAV) is a major public health problem and a pandemic threat. Its evolution is largely driven by diversifying positive selection so that relative fitness of different amino acid variants ...
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