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2024-3-29 21:16:13
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Takashi Kuzuhara, Daisuke Kise, Hiroko Yoshida, Ta. Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. J. Biol. Chem, 10.1074/jbc.C800224200.  Abstract  
submitted by kickingbird at Feb, 5, 2009 from J. Biol. Chem, 10.1074/jbc.C800224200 (via http://www.jbc.org/cgi/content/abstract/C800224200v1)
Since the influenza A virus has an RNA genome, its RNA-dependent RNA polymerase, comprising the PA, PB1 and PB2 subunits, is essential for viral transcription and replication. The binding of RNA primers/promoters ...

Oleg P Zhirnov, Vladimir V Syrtzev. Influenza virus pathogenicity is determined by caspase cleavage motifs located in viral proteins. J Mol Genet Med (January 2009), 3(1), 124-132.  Abstract  
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 124-132 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Zhirnov.htm)
Almost all influenza virus proteins are found to contain caspase cleavage motifs. Two caspase cleavage consensus sequences, EXD|Y and D/EXXD|Y (caspase motifs) were identified in N- and C-terminal regions ...

Mosleh, etc.,al. Molecular quantitation of H9N2 avian influenza virus in various organs of broiler chickens using TaqMan real time PCR. J Mol Genet Med (January 2009), 3(1), 152-157.  Abstract  
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 152-157 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Mosleh.htm)
During the past decade, H9N2 low pathogenic avian influenza virus (LPAI) has caused considerable economic loss due to decreased production, increased mortality and the cost of vaccination in Iranian poultry ...

Kuchipudi, etc.,al. Differences in influenza virus receptors in chickens and ducks: Implications for interspecies transmission. J Mol Genet Med (January 2009), 3(1), 143-151.  Abstract  
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 143-151 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Kuchipudi.h)
Short Report J Mol Genet Med (January 2009), 3(1), 143-151 doi: jmgm Published online: 16 January 2009 Full Text: (html | pdf ~1440kb | refs) Differences in influenza virus receptors ...

Munir Iqbal. Controlling avian influenza infections: The challenge of the backyard poultry. J Mol Genet Med (January 2009), 3(1), 119-120.  Full Text  
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 119-120 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Iqbal.htm)
In recent years the economic damage inflicted by several avian influenza (AI) subtypes (primarily H5N1 and H9N2, but also H7N1, H7N3, H7N7) on the commercial poultry industry and backyard poultry is beyond ...

Kalhoro NH, Veits J, Rautenschlein S, Zimmer G. A recombinant vesicular stomatitis virus replicon vaccine protects chickens from highly pathogenic avian influenza virus (H7N1).. Vaccine. 2009 Jan 6..  Abstract  
submitted by kickingbird at Jan, 18, 2009 from Vaccine. 2009 Jan 6. (via http://www.ncbi.nlm.nih.gov/pubmed/19135116)
Highly pathogenic avian influenza viruses (HPAIV) of subtypes H5 and H7 cause fatal disease in poultry (fowl plague) but also have zoonotic potential. Currently commercially available vaccines often do ...

Khurana E, Peraro MD, Devane R, Vemparala S, Degra. Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus. Proc Natl Acad Sci U S A. 2009 Jan 14.  Abstract  
submitted by kickingbird at Jan, 18, 2009 from Proc Natl Acad Sci U S A. 2009 Jan 14 (via http://www.ncbi.nlm.nih.gov/pubmed/19144924)
The M2 protein of the influenza A virus is activated by low endosomal pH and performs the essential function of proton transfer into the viral interior. The resulting decrease in pH within the virion is ...

Van Hoeven N, Belser JA, Szretter KJ, Zeng H, Stae. Pathogenesis of the 1918 pandemic and H5N1 influenza virus infection in a guinea pig model: The antiviral potential of exogenous alpha-interferon to reduce virus shedding. J Virol. 2009 Jan 14..  Abstract  
submitted by kickingbird at Jan, 18, 2009 from J Virol. 2009 Jan 14. (via http://www.ncbi.nlm.nih.gov/pubmed/19144714)
Although highly pathogenic avian influenza H5N1 viruses have yet to acquire the ability to transmit efficiently among humans, the increasing genetic diversity among these viruses, and continued outbreaks ...

Monne I, Fusaro A, Al-Blowi MH, Ismail MM, Khan OA. Co-circulation of two sublineages of HPAI H5N1 virus in the Kingdom of Saudi Arabia with unique molecular signatures suggesting separate introductions into the commercial poultry and falconry sectors. J Gen Virol. 2008 Nov;89(Pt 11):2691-7.  Abstract  
submitted by kickingbird at Jan, 18, 2009 from J Gen Virol. 2008 Nov;89(Pt 11):2691-7 (via http://www.ncbi.nlm.nih.gov/pubmed/18931064)
Since early 2007, the Kingdom of Saudi Arabia (KSA) has experienced several highly pathogenic avian influenza (HPAI) H5N1 outbreaks in the falconry and poultry sectors. The public health threat associated ...

Wressnigg N, Shurygina AP, Wolff T, Redlburger-Fri. Influenza B mutant viruses with truncated NS1 proteins grow efficiently in Vero cells and are immunogenic in mice. J Gen Virol. 2009 Feb;90(Pt 2):366-74.  Abstract  
submitted by kickingbird at Jan, 18, 2009 from J Gen Virol. 2009 Feb;90(Pt 2):366-74 (via http://www.ncbi.nlm.nih.gov/pubmed/19141445)
Contemporary influenza B virus strains were generated encoding C-terminally truncated NS1 proteins. Viable viruses containing the N-terminal 14, 38, 57 or 80 aa of the NS1 protein were rescued in Vero ...

Masic A, Babiuk LA, Zhou Y.. Reverse genetics-generated elastase-dependent swine influenza viruses are attenuated in pigs.. J Gen Virol. 2009 Feb;90(Pt 2):375-85.  Abstract  
submitted by kickingbird at Jan, 18, 2009 from J Gen Virol. 2009 Feb;90(Pt 2):375-85 (via http://www.ncbi.nlm.nih.gov/pubmed/19141446)
Influenza A virus causes significant morbidity in swine, resulting in a substantial economic burden. Swine influenza virus (SIV) infection also poses important human public health concerns. It has been ...

Tang X, Chong KT. Histopathology and growth kinetics of influenza viruses (H1N1 and H3N2) in the upper and lower airways of guinea pigs. J Gen Virol. 2009 Feb;90(Pt 2):386-91..  Abstract  
submitted by kickingbird at Jan, 18, 2009 from J Gen Virol. 2009 Feb;90(Pt 2):386-91. (via http://www.ncbi.nlm.nih.gov/pubmed/19141447)
Recent investigations have shown that guinea pigs are important for the study of influenza A virus (IAV) transmission. However, very little is known about IAV replication and histopathology in the guinea ...

Tao P, Luo M, Pan R, Lin D, Zhou S, Tien P, Pan Z.. Enhanced protective immunity against H5N1 influenza virus challenge by vaccination with DNA expressing a chimeric hemagglutinin in combination with an MHC class I-restricted epitope of nucleoprotein i. Antiviral Res. 2009 Jan 7.  Abstract  
submitted by kickingbird at Jan, 18, 2009 from Antiviral Res. 2009 Jan 7 (via http://www.ncbi.nlm.nih.gov/pubmed/19135483)
DNA vaccination is an effective means of eliciting both humoral and cellular immune responses. The hemagglutinin (HA) surface protein of influenza A virus is a major target of protective antibody responses ...

Shien JH, Fu LF, Wu JR, Cheng MC, Shieh HK, Chang. Development of blocking ELISA for detection of antibodies against avian influenza virus of the H7 subtype. J Microbiol Immunol Infect. 2008 Oct;41(5):369-76.  Abstract  
submitted by kickingbird at Jan, 6, 2009 from J Microbiol Immunol Infect. 2008 Oct;41(5):369-76 (via http://www.ncbi.nlm.nih.gov/pubmed/19122917?ordinalpos=1&ito)
BACKGROUND AND PURPOSE: The conventional method used for subtyping of antibodies against avian influenza viruses is hemagglutination inhibition (HI) test. However, the HI test is laborious and requires ...

Cooley P, Ganapathi L, Ghneim G, Holmberg S, Wheat. Using Influenza-Like Illness Data to Reconstruct an Influenza Outbreak. Math Comput Model. 2008;48(5-6):929-939..  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Math Comput Model. 2008;48(5-6):929-939. (via http://www.ncbi.nlm.nih.gov/pubmed/19122846?ordinalpos=2&ito)
The objective of this study was to reconstruct the type A influenza epidemic that occurred in the Research Triangle Park (RTP) region of North Carolina during the 2003-04 flu season. We describe an agent-based ...

Wahl A, Schafer F, Bardet W, Buchli R, Air GM, Hil. HLA class I molecules consistently present internal influenza epitopes. Proc Natl Acad Sci U S A. 2009 Jan 2.  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Proc Natl Acad Sci U S A. 2009 Jan 2 (via http://www.ncbi.nlm.nih.gov/pubmed/19122146?ordinalpos=4&ito)
Cytotoxic T lymphocytes (CTL) limit influenza virus replication and prevent morbidity and mortality upon recognition of HLA class I presented epitopes on the surface of virus infected cells, yet the number ...

Zhang Z, Zhang J, Huang K, Li KS, Yuen KY, Guan Y,. Systemic infection of avian influenza A virus H5N1 subtype in human. Hum Pathol. 2009 Jan 2..  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Hum Pathol. 2009 Jan 2. (via http://www.ncbi.nlm.nih.gov/pubmed/19121843?ordinalpos=6&ito)
The viral dissemination in a patient with avian influenza A subtype H5N1 infection was retrospectively studied by the immunohistochemical localization of viral nucleoprotein antigen. The pathology was ...

Smith BW, Kay VS, Hoyt TV, Bernard ML.. Predicting the anticipated emotional and behavioral responses to an avian flu outbreak. Am J Infect Control. 2008 Dec 31.  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Am J Infect Control. 2008 Dec 31 (via http://www.ncbi.nlm.nih.gov/pubmed/19121548?ordinalpos=7&ito)
BACKGROUND: The purpose of this study was to develop a model to predict the emotional and behavioral responses to an avian flu outbreak. METHODS: The participants were 289 university students ranging in ...

White MR, Helmerhorst EJ, Ligtenberg A, Karpel M,. Multiple components contribute to ability of saliva to inhibit influenza viruses. Oral Microbiol Immunol. 2009 Feb;24(1):18-24..  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Oral Microbiol Immunol. 2009 Feb;24(1):18-24. (via http://www.ncbi.nlm.nih.gov/pubmed/19121065?ordinalpos=8&ito)
INTRODUCTION: Saliva is a potentially important barrier against respiratory viral infection but its mechanism of action is not well studied. METHODS: We tested the antiviral activities of whole saliva, ...

Maillard JC, Van KP, Nguyen T, Van TN, Berthouly C. Examples of probable host-pathogen co-adaptation/co-evolution in isolated farmed animal populations in the mountainous regions of North Vietnam. Ann N Y Acad Sci. 2008 Dec;1149:259-62.  Abstract  
submitted by kickingbird at Jan, 6, 2009 from Ann N Y Acad Sci. 2008 Dec;1149:259-62 (via http://www.ncbi.nlm.nih.gov/pubmed/19120225?ordinalpos=12&it)
In Vietnam, for a number of specific geographical and historical reasons, the mountainous areas have preserved an exceptional diversity of wild and domestic animal species of high socioeconomic interest. ...

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