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2024-5-8 22:22:26
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Xu Y, Tang L, Gu X, Bo S, Ming L, Ma M, Zhao C, Su. Characterization of avian influenza A (H4N2) viruses isolated from wild birds in Shanghai during 2019 to 2021. Poult Sci. 2023 Jul 26;102(10):102948.  Abstract  
submitted by kickingbird at Aug, 22, 2023 from Poult Sci. 2023 Jul 26;102(10):102948 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H4 subtype of avian influenza viruses has been widely distributed among wild birds. During the surveillance of the avian influenza virus in Shanghai from 2019 to 2021, a total of 4,451 samples were ...

Min J, Li Y, Li X, Wang M, Li H, Bi Y, Xu P, Liu W. The circRNA circVAMP3 restricts influenza A virus replication by interfering with NP and NS1 proteins. PLoS Pathog. 2023 Aug 21;19(8):e1011577.  Abstract  
submitted by kickingbird at Aug, 22, 2023 from PLoS Pathog. 2023 Aug 21;19(8):e1011577 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Circular RNAs (circRNAs) are involved in various biological roles, including viral infection and antiviral immune responses. To identify influenza A virus (IAV) infection-related circRNAs, we compared ...

Sun X, Belser JA, Pulit-Penaloza JA, Brock N, Papp. Pathogenesis and transmission assessment of three swine-origin influenza A(H3N2) viruses with zoonotic risk to humans isolated in the U.S from 2017-2020. J Infect Dis. 2023 Aug 21:jiad359.  Abstract  
submitted by kickingbird at Aug, 22, 2023 from J Infect Dis. 2023 Aug 21:jiad359 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
The sporadic occurrence of human infections with swine-origin influenza A(H3N2) viruses and the continual emergence of novel A(H3N2) viruses in swine herds underscore the necessity for ongoing assessment ...

Louie AY, Kim JS, Drnevich J, Dibaeinia P, Koito H. Influenza A virus infection disrupts oligodendrocyte homeostasis and alters the myelin lipidome in the adult mouse. J Neuroinflammation. 2023 Aug 19;20(1):190.  Abstract  
submitted by kickingbird at Aug, 21, 2023 from J Neuroinflammation. 2023 Aug 19;20(1):190 (via https://jneuroinflammation.biomedcentral.com/articles/10.118)
Background: Recent data suggest that myelin may be altered by physiological events occurring outside of the central nervous system, which may cause changes to cognition and behavior. Similarly, peripheral ...

Alalem M, Dabous E, Awad AM, Alalem N, Guirgis AA,. Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication. Virol J. 2023 Aug 18;20(1):183.  Abstract  
submitted by kickingbird at Aug, 21, 2023 from Virol J. 2023 Aug 18;20(1):183 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
The antiviral response against influenza A virus (IAV) infection includes the induction of the interferon (IFN) signaling pathway, including activation of the STATs protein family. Subsequently, antiviral ...

David SC, Vadas O, Glas I, Schaub A, Luo B, D&acut. Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS. mSphere. 2023 Aug 18:e0022623.  Abstract  
submitted by kickingbird at Aug, 21, 2023 from mSphere. 2023 Aug 18:e0022623 (via https://journals.asm.org/doi/10.1128/msphere.00226-23)
Multiple respiratory viruses, including influenza A virus (IAV), can be transmitted via expiratory aerosol particles, and aerosol pH was recently identified as a major factor influencing airborne virus ...

El-Shall NA, Abd El Naby WSH, Hussein EGS, Yonis A. Pathogenicity of H5N8 avian influenza virus in chickens and in duck breeds and the role of MX1 and IFN-α in infection outcome and transmission to contact birds. Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100:.  Abstract  
submitted by kickingbird at Aug, 21, 2023 from Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100: (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
This study examined the pathogenicity, immunogenicity, and transmission potential of the H5N8 HPAI clade 2.3.4.4b virus in three breeds of ducks and in broiler chickens. Chickens, Muscovy, Pekin, and Mallard ...

Cronk BD, Caserta LC, Laverack M, Gerdes RS, Hynes. Infection and tissue distribution of Highly Pathogenic Avian Influenza A type H5N1 (clade 2.3.4.4b) in Red Fox kits ( Vulpes vulpes). Emerg Microbes Infect . 2023 Aug 17;2249554.  Abstract  
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect . 2023 Aug 17;2249554 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Avian influenza H5N1 is a highly pathogenic virus that primarily affects birds. However, it can also infect other animal species, including mammals. We report the infection of nine juvenile red foxes (Vulpes ...

Li J, Fang Y, Qiu X, Yu X, Cheng S, Li N, Sun Z, N. Human infection with avian-origin H5N6 influenza a virus after exposure to slaughtered poultry. Emerg Microbes Infect. 2022 Dec;11(1):807-810.  Abstract  
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2022 Dec;11(1):807-810 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
Exposure to poultry in live poultry markets is strongly associated with human infection with avian influenza virus. To effectively prevent the transmission of viruses from live poultry to humans, people ...

Zhang L, Liu K, Su Q, Chen X, Wang X, Li Q, Wang W. Clinical features of the first critical case of acute encephalitis caused by the avian influenza A (H5N6) virus. Emerg Microbes Infect. 2022 Dec;11(1):2437-2446.  Abstract  
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2022 Dec;11(1):2437-2446 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2022.2)
Highly pathogenic avian influenza viruses (HPAIV), such as H5N1, H5N6, and H7N9, have been reported to frequently infect humans, but acute encephalitis caused by HPAIV in humans has been rarely reported. ...

Bergant V, Schnepf D, de Andrade Kr?tzig N, Hubel. mRNA 3´UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus. Nat Commun. 2023 Aug 15;14(1):4906.  Abstract  
submitted by kickingbird at Aug, 17, 2023 from Nat Commun. 2023 Aug 15;14(1):4906 (via https://www.nature.com/articles/s41467-023-40469-6)
Changes of mRNA 3'UTRs by alternative polyadenylation (APA) have been associated to numerous pathologies, but the mechanisms and consequences often remain enigmatic. By combining transcriptomics, proteomics ...

Wang X, Liu K, Guo Y, Pei Y, Chen X, Lu X, Gao R,. Emergence of a new designated clade 16 with significant antigenic drift in hemagglutinin gene of H9N2 subtype avian influenza virus in eastern China. Emerg Microbes Infect. 2023 Aug 16:2249558.  Abstract  
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2023 Aug 16:2249558 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
H9N2 avian influenza viruses (AIVs) pose an increasing threat to the poultry industry worldwide and have pandemic potential. Vaccination has been principal prevention strategy to control H9N2 in China ...

Huang X, Cai Y, Yin G, Chen Z, Hu J, Gao Z, Guo X,. Identification of catalytically active domain epitopes in neuraminidase protein of H9N2 subtype of avian influenza virus. Avian Pathol. 2023 Aug 15:1-11.  Abstract  
submitted by kickingbird at Aug, 16, 2023 from Avian Pathol. 2023 Aug 15:1-11 (via https://www.tandfonline.com/doi/abs/10.1080/03079457.2023.22)
H9N2 subtype of avian influenza virus (AIV) is primarily a bird virus, which is widespread in clinical avian disease, and reported in cases of human infection. As one of the surface proteins of AIV, the ...

Xia J, Li YX, Dong MY, Guo ZW, Luo YW, Li NL, Zhao. Evolution of prevalent H9N2 subtype of avian influenza virus during 2019 to 2022 for the development of a control strategy in China. Poult Sci. 2023 Jul 25;102(10):102957.  Abstract  
submitted by kickingbird at Aug, 16, 2023 from Poult Sci. 2023 Jul 25;102(10):102957 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus (H9N2 AIV) has caused significant losses in chicken flocks throughout China. At present, consensus has been reached that field isolates of H9N2 underwent antigenic ...

Youk S, Torchetti MK, Lantz K, Lenoch JB, Killian. H5N1 highly pathogenic avian influenza clade 2.3.4.4b in wild and domestic birds: Introductions into the United States and reassortments, December 2021-April 2022. Virology. 2023 Aug 2;587:109860.  Abstract  
submitted by kickingbird at Aug, 14, 2023 from Virology. 2023 Aug 2;587:109860 (via https://www.sciencedirect.com/science/article/pii/S004268222)
Highly pathogenic avian influenza viruses (HPAIVs) of the A/goose/Guangdong/1/1996 lineage H5 clade 2.3.4.4b continue to have a devastating effect on domestic and wild birds. Full genome sequence analyses ...

Kok A, Scheuer R, Bestebroer TM, Burke DF, Wilks S. Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution. mBio. 2023 Aug 11:e0048823.  Abstract  
submitted by kickingbird at Aug, 12, 2023 from mBio. 2023 Aug 11:e0048823 (via https://journals.asm.org/doi/10.1128/mbio.00488-23)
Avian A/H7 influenza viruses are a global threat to animal and human health. These viruses continue to cause outbreaks in poultry and have caused the highest number of reported zoonotic infections to date, ...

Zhuang Y, Wang M, Liang L, Mao Y, Wang K, Yang S,. The first known human death after infection with the avian influenza (A/H3N8) virus: Guangdong Province, China, March 2023. Clin Infect Dis. 2023 Aug 9:ciad462.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from Clin Infect Dis. 2023 Aug 9:ciad462 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
We reported a case of human infection with the H3N8 avian influenza virus, who had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without ...

Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. iScience. 2023 Jul 14;26(8):107361.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from iScience. 2023 Jul 14;26(8):107361 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01438-4)
Individuals with Down syndrome (DS) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how DS influences homeostatic physiology of lung airway, and its reactive responses ...

Tonouchi K, Adachi Y, Suzuki T, Kuroda D, Nishiyam. Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope. PLoS Pathog. 2023 Aug 9;19(8):e1011554.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from PLoS Pathog. 2023 Aug 9;19(8):e1011554 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Plasticity of influenza virus hemagglutinin (HA) conformation increases an opportunity to generate conserved non-native epitopes with unknown functionality. Here, we have performed an in-depth analysis ...

Xie Q, Liao X, Huang B, Wang L, Liao G, Luo C, Wen. The truncated IFITM3 facilitates the humoral immune response in inactivated influenza vaccine-vaccinated mice via interaction with CD81. Emerg Microbes Infect. 2023 Aug 9:2246599.  Abstract  
submitted by kickingbird at Aug, 10, 2023 from Emerg Microbes Infect. 2023 Aug 9:2246599 (via https://pubmed.ncbi.nlm.nih.gov/37556756/)
A single-nucleotide polymorphism (SNP) rs12252-C of interferon-induced transmembrane protein 3 (IFITM3), resulting in a truncated IFITM3 protein lacking 21 N-terminus amino acids, is associated with severe ...

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