-

nihao guest [ sign in / register ]
2024-3-29 1:42:46
Article

HUI DS, Lee N, Chan PK. Adjunctive therapies and immunomodulatory agents in the management of severe influenza. Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008.  Abstract  
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 8. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23578727)
In addition to neuraminidase inhibitors and other drugs that directly target viral replication, a number of adjunctive and immunomodulatory therapies are currently under evaluation for the treatment of ...

LAURSEN NS, Wilson IA. Broadly neutralizing antibodies against influenza viruses. Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008.  Abstract  
submitted by kickingbird at Apr, 21, 2013 from Antiviral Res. 2013 Apr 9. pii: S0166-3542(13)0008 (via http://www.ncbi.nlm.nih.gov/pubmed/23583287)
Despite available antivirals and vaccines, influenza continues to be a major cause of mortality worldwide. Vaccination generally induces an effective, but strain-specific antibody response. As the virus ...

Jonges M, Meijer A, Fouchier RA, Koch G, Li J, Pan. Guiding outbreak management by the use of influenza A(H7Nx) virus sequence analysis. Euro Surveill. 2013;18(16):pii=20460..  Full Text  
submitted by kickingbird at Apr, 20, 2013 from Euro Surveill. 2013;18(16):pii=20460. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
The recently identified human infections with avian influenza A(H7N9) viruses in China raise important questions regarding possible source and risk to humans. Sequence comparison with an influenza A(H7N7) ...

TAFESSE FG, Sanyal S, Ashour J, Guimaraes CP, et a. Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins.. Proc Natl Acad Sci U S A. 2013 Apr 1.  Abstract  
submitted by kickingbird at Apr, 14, 2013 from Proc Natl Acad Sci U S A. 2013 Apr 1 (via http://www.ncbi.nlm.nih.gov/pubmed/23576732)
Cells genetically deficient in sphingomyelin synthase-1 (SGMS1) or blocked in their synthesis pharmacologically through exposure to a serine palmitoyltransferase inhibitor (myriocin) show strongly reduced ...

Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Ji. Replication and immunogenicity of swine, equine and avian H3 subtype influenza viruses in mice and ferrets. J Virol. 2013 Apr 10..  Abstract  
submitted by kickingbird at Apr, 14, 2013 from J Virol. 2013 Apr 10. (via http://www.ncbi.nlm.nih.gov/pubmed/23576512)
Since it is difficult to predict which influenza virus subtype will cause an influenza pandemic, it is important to prepare influenza virus vaccines against different subtypes and evaluate the safety and ...

RB Gao, B Cao,YW Hu, ZJ Feng, DY Wang, etc.,al. Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus. April 11, 2013DOI: 10.1056/NEJMoa1304459.  Abstract  
submitted by kickingbird at Apr, 12, 2013 from April 11, 2013DOI: 10.1056/NEJMoa1304459 (via http://www.nejm.org/doi/full/10.1056/NEJMoa1304459?query=fea)
Background Infection of poultry with influenza A subtype H7 viruses occurs worldwide, but the introduction of this subtype to humans in Asia has not been observed previously. In March 2013, three urban ...

Nicoll A, Danielsson N.. A novel reassortant avian influenza A(H7N9) virus in China – what are the implications for Europe. Euro Surveill. 2013;18(15):pii=20452..  Abstract  
submitted by kickingbird at Apr, 12, 2013 from Euro Surveill. 2013;18(15):pii=20452. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
As of 10 April 2013, 33 human cases infected with a novel influenza A(H7N9) virus have been laboratory confirmed in Shanghai, Anhui, Jiangsu and Zhejiang provinces in China (Figure1). This case count came ...

Feifei Yang, etc.,al. A fatal case caused by novel H7N9 avian influenza A virus in China. Emerging Microbes & Infections (2013) 2, e19.  Full Text  
submitted by kickingbird at Apr, 11, 2013 from Emerging Microbes & Infections (2013) 2, e19 (via http://www.nature.com/emi/journal/v2/n4/full/emi201322a.html)
Since the highly pathogenic H5N1 avian influenza virus (AIV) was first transmitted from birds to humans in Hong Kong in 1997, other pathogenic AIVs, including H7N2, H7N3, H7N7, and H9N2 have been reported ...

CHAKRABARTI AK, Pasricha G.. An insight into the PB1F2 protein and its multifunctional role in enhancing the pathogenicity of the influenza A viruses. Virology. 2013 Mar 29. pii: S0042-6822(13)00130.  Abstract  
submitted by kickingbird at Apr, 7, 2013 from Virology. 2013 Mar 29. pii: S0042-6822(13)00130 (via http://www.ncbi.nlm.nih.gov/pubmed/23545143)
PB1F2 is the 11th protein of the influenza A virus. The protein has variable sizes with truncations either at the C- or N-terminal ends. The most recent example being the 2009 pandemic H1N1 virus which ...

Wang S, Zhao Z, Bi Y, Sun L, et al.. Tyrosine 132 phosphorylation of influenza A virus M1 protein is crucial for virus replication by controlling its nuclear import. J Virol 2013.  Abstract  
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536660/)
Phosphorylation of viral protein plays important roles in the influenza A virus (IAV) life cycle. By using mass spectrometry, we have identified tyrosine (Y) 132 as a phosphorylation site of matrix protein ...

Martinez-Romero C, de Vries E, Belicha-Villanueva. Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. J Virol 2013.  Abstract  
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536663/)
We describe that swine influenza virus-like substitutions T200A and E227A in the hemagglutinin of the 2009 pandemic influenza virus alter its pathogenesis and transmission. Viral replication is increased ...

Graham AC, Hilmer KM, Zickovich JM, Obar JJ, et al. Inflammatory Response of Mast Cells during Influenza A Virus Infection Is Mediated by Active Infection and RIG-I Signaling. J Immunol 2013..  Abstract  
submitted by kickingbird at Apr, 1, 2013 from J Immunol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/23526820/)
Influenza A virus (IAV) is a major respiratory pathogen of both humans and animals. The lung is protected from pathogens by alveolar epithelial cells, tissue-resident alveolar macrophages, dendritic cells, ...

Lee YN, Youn HN, Kwon JH, Lee DH, et al. Sublingual administration of Lactobacillus rhamnosus affects respiratory immune responses and facilitates protection against influenza virus infection in mice. Antiviral Res 2013 Mar 20. pii: S0166-3542(13)0006.  Abstract  
submitted by kickingbird at Apr, 1, 2013 from Antiviral Res 2013 Mar 20. pii: S0166-3542(13)0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23523767/)
The extensive morbidity and mortality caused by influenza A viruses worldwide prompts the need for a deeper understanding of the host immune response and novel therapeutic and/or prophylactic interventions. ...

Samson M, Pizzorno A, Abed Y, Boivin G, et al.. Influenza Virus Resistance to Neuraminidase Inhibitors. Antiviral Res 2013 Mar 21. pii: S0166-3542(13)0006.  Abstract  
submitted by kickingbird at Apr, 1, 2013 from Antiviral Res 2013 Mar 21. pii: S0166-3542(13)0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23523943/)
In addition to immunization programs, antiviral agents can play a major role for the control of seasonal influenza epidemics and may also provide prophylactic and therapeutic benefits during an eventual ...

Bertran K, Pérez-Ramírez E, Busquets N, Dolz R, Ra. Pathogenesis and transmissibility of highly (H7N1) and low (H7N9) pathogenic avian influenza virus infection in red-legged partridge (Alectoris rufa).. Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97.  Abstract  
submitted by kickingbird at Mar, 31, 2013 from Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97 (via http://www.ncbi.nlm.nih.gov/pubmed/21314907)
An experimental infection with highly pathogenic avian influenza virus (HPAIV) and low pathogenic avian influenza virus (LPAIV) was carried out in red-legged partridges (Alectoris rufa) in order to study ...

Pérez-Ramírez E, Gerrikagoitia X, Barral M, H?fle. Detection of low pathogenic avian influenza viruses in wild birds in Castilla-La Mancha (south central Spain).. Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10.  Abstract  
submitted by kickingbird at Mar, 31, 2013 from Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10 (via http://www.ncbi.nlm.nih.gov/pubmed/20605691)
The Iberian Peninsula is located along the East Atlantic and Black Sea/Mediterranean flyways and is the third ranking European country as wintering quarter for wild migrating birds after Turkey and Rumania. ...

HARRIS AK, Meyerson JR, Matsuoka Y, Kuybeda O, et. Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies. Proc Natl Acad Sci U S A. 2013 Mar 4.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from Proc Natl Acad Sci U S A. 2013 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/23460696)
Rapid antigenic variation of HA, the major virion surface protein of influenza A virus, remains the principal challenge to the development of broader and more effective vaccines. Some regions of HA, such ...

SANTOS A, Pal S, Chacon J, Meraz K, et al. SUMOylation affects the interferon blocking activity of the influenza A non-structural protein NS1 without affecting its stability or cellular localization. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468495)
Our pioneering studies on the interplay between the Small Ubiquitin-like MOdifier (SUMO) and influenza A virus identified the non-structural NS1 protein as the first known SUMO target of influenza virus ...

PETERSEN H, Wang Z, Lenz E, Pleschka S, et al. Reassortment of NS-segments modifies highly-pathogenic avian influenza virus interaction with avian hosts and host cells. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468508)
Highly pathogenic avian influenza viruses (HPAIV) of subtypes H5 and H7 have caused numerous outbreaks in diverse poultry species and rising numbers of human infections. Both HPAIV subtypes support a growing ...

Fontana J, Steven AC.. At low pH, Influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane. J Virol. 2013 Mar 6.  Abstract  
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468509)
The M1 matrix protein of influenza A virus, which plays multiple roles in virion assembly and infection, underlies the viral envelope. However, previous studies have given differing accounts of the number ...

7429 items, 20/Page, Page[265/372][|<<] [|<] [261] [262] [263] [264] [265] [266] [267] [268] [269] [270] [>|] [>>|]

Related Pages:

Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!


  

Site map  |   Contact us  |  Term of use  |  FAQs |  粤ICP备10094839号-1
Copyright ©www.flu.org.cn. 2004-2024. All Rights Reserved. Powered by FIC 4.0.1
  Email:webmaster@flu.org.cn