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2024-7-18 5:31:46
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GAO H, Xu G, Sun Y, Qi L, et al. PA-X is a virulence factor in avian H9N2 influenza virus. J Gen Virol. 2015 Jul 9. doi: 10.1099/jgv.0.000232.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jul 9. doi: 10.1099/jgv.0.000232 (via http://www.ncbi.nlm.nih.gov/pubmed/26296365)
H9N2 influenza viruses have been circulating worldwide in multiple avian species and regularly infect pigs and humans. Recently, a novel protein PA-X, produced from ribosomal frame-shift during PA translation, ...

XU F, Liu G, Liu Q, Zhou Y, et al. RNA interference of influenza A virus replication by microRNA-adapted lentiviral shRNA. J Gen Virol. 2015 Jul 17. doi: 10.1099/jgv.0.00024.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jul 17. doi: 10.1099/jgv.0.00024 (via http://www.ncbi.nlm.nih.gov/pubmed/26296570)
Limitations of the current vaccines and antivirals against influenza A virus pandemic underscores the urgent need for developing a novel anti-influenza strategies. RNA interference (RNAi) induced by small ...

WU NH, Meng F, Seitz M, Valentin-Weigand P, et al. Sialic acid-dependent interactions between influenza viruses and Streptococcus suis affect the infection of porcine tracheal cells. J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022 (via http://www.ncbi.nlm.nih.gov/pubmed/26297001)
Bacterial co-infections are a major complication in influenza virus-induced disease both in humans and animals. Either of the pathogens may induce a host response that affects the infection by the other ...

SUN H, Cunningham F, Harris J, Xu Y, et al. Dynamics of Virus Shedding and Antibody Responses in Influenza A Virus-Infected Feral Swine. J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022.  Abstract  
submitted by kickingbird at Aug, 30, 2015 from J Gen Virol. 2015 Jun 25. doi: 10.1099/jgv.0.00022 (via http://www.ncbi.nlm.nih.gov/pubmed/26297148)
Given their free-ranging habits, feral swine could serve as reservoirs or spatially dynamic "mixing vessels" for influenza A virus (IAV). To better understand virus shedding patterns and antibody response ...

MARCHENKO VY, Susloparov IM, Kolosova NP, Goncharo. Influenza A(H5N8) virus isolation in Russia, 2014. Arch Virol. 2015 Aug 26..  Abstract  
submitted by kickingbird at Aug, 30, 2015 from Arch Virol. 2015 Aug 26. (via http://www.ncbi.nlm.nih.gov/pubmed/26306756)
In this study, we report the isolation of influenza A(H5N8) virus from a Eurasian wigeon (Anas penelope) in Sakha Republic of the Russian Far East. The strain A/wigeon/Sakha/1/2014 (H5N8) has been shown ...

Xie S, Jia W, Lin Y, Xing K, Ren X, Qi W, et al. Third Wave of Influenza A(H7N9) Virus from Poultry, Guangdong Province, China, 2014–2015. Emerg Infect Dis. 2015 Sep.  Abstract  
submitted by kickingbird at Aug, 24, 2015 from Emerg Infect Dis. 2015 Sep (via http://wwwnc.cdc.gov/eid/article/21/9/15-0635_article)
Fourteen influenza A(H7N9) viruses were isolated from poultry or the environment in live poultry markets in Guangdong Province, China during 2014?2015. Phylogenetic analysis showed that all viruses were ...

S. Chaves et al.. The US Influenza Hospitalization Surveillance Network. Emerg Infect Dis. 2015 Sep.  Abstract  
submitted by kickingbird at Aug, 24, 2015 from Emerg Infect Dis. 2015 Sep (via http://wwwnc.cdc.gov/eid/article/21/9/14-1912_article)
In 2003, surveillance for influenza in hospitalized persons was added to the Centers for Disease Control and Prevention Emerging Infections Program network. This surveillance enabled monitoring of the ...

KINGSTAD-BAKKE B, Kamlangdee A, Osorio JE. Mucosal administration of raccoonpox virus expressing highly pathogenic avian H5N1 influenza neuraminidase is highly protective against H5N1 and seasonal influenza virus challenge. Vaccine. 2015 Aug 10. pii: S0264-410X.  Abstract  
submitted by kickingbird at Aug, 23, 2015 from Vaccine. 2015 Aug 10. pii: S0264-410X (via http://www.ncbi.nlm.nih.gov/pubmed/26271828)
We previously generated recombinant poxviruses expressing influenza antigens and studied their efficacy as potential highly pathogenic avian influenza (HPAI) vaccines in mice. While both modified vaccinia ...

MANCEUR AP, Kamen AA.. Critical review of current and emerging quantification methods for the development of influenza vaccine candidates. Vaccine. 2015 Aug 10. pii: S0264-410X.  Abstract  
submitted by kickingbird at Aug, 23, 2015 from Vaccine. 2015 Aug 10. pii: S0264-410X (via http://www.ncbi.nlm.nih.gov/pubmed/26271833)
Significant improvements in production and purification have been achieved since the first approved influenza vaccines were administered 75 years ago. Global surveillance and fast response have limited ...

SONG MS, Marathe BM, Kumar G, Wong SS, et al. Unique determinants of neuraminidase inhibitor resistance among N3, N7, and N9 avian influenza viruses. J Virol. 2015 Aug 19.  Abstract  
submitted by kickingbird at Aug, 23, 2015 from J Virol. 2015 Aug 19 (via http://www.ncbi.nlm.nih.gov/pubmed/26292325)
Human infections with avian influenza viruses are a serious public health concern. The neuraminidase (NA) inhibitors (NAIs) are the frontline anti-influenza drugs and are the major option for treatment ...

FAN RL, Valkenburg SA, Wong CK, Li OT, et al. Generation of live attenuated influenza virus using codon usage bias. J Virol. 2015 Aug 12. pii: JVI.01443-15..  Abstract  
submitted by kickingbird at Aug, 16, 2015 from J Virol. 2015 Aug 12. pii: JVI.01443-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26269186)
Seasonal influenza epidemics and occasional pandemics threaten public health worldwide. New alternative strategies for generating recombinant viruses of vaccine potential are needed. Interestingly, influenza ...

WANG W, DeFeo CJ, Alvarado E, Vassell R, et al. Intermonomer Interactions in Hemagglutinin subunits HA1 and HA2 Affecting Hemagglutinin Stability and Influenza Virus Infectivity. J Virol. 2015 Aug 12. pii: JVI.00939-15.  Abstract  
submitted by kickingbird at Aug, 16, 2015 from J Virol. 2015 Aug 12. pii: JVI.00939-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26269180)
Influenza virus hemagglutinin (HA) mediates virus entry by binding to cell surface receptors and fusing the viral and endosomal membranes following uptake by endocytosis. The acidic environment of endosomes ...

TURKINGTON HL, Juozapaitis M, Kerry PS, Aydillo T,. Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity. J Virol. 2015 Aug 5. pii: JVI.01430-15.  Abstract  
submitted by kickingbird at Aug, 10, 2015 from J Virol. 2015 Aug 5. pii: JVI.01430-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26246567)
We demonstrate that novel bat HL17NL10 and HL18NL11 influenza virus NS1 proteins are effective interferon-antagonists, but do not block general host gene expression. Solving the RNA-binding domain structures ...

DIEDERICH S, Berhane Y, Embury-Hyatt C, Hisanaga T. Hemagglutinin-Neuraminidase Balance Influences the Virulence Phenotype of a Recombinant H5N3 Influenza A Virus Possessing a Polybasic HA0 Cleavage Site. J Virol. 2015 Aug 5. pii: JVI.01238-15..  Abstract  
submitted by kickingbird at Aug, 10, 2015 from J Virol. 2015 Aug 5. pii: JVI.01238-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26246579)
Although a polybasic HA0 cleavage site is considered the dominant virulence determinant for highly pathogenic avian influenza (HPAI) H5 and H7 viruses, naturally occurring virus isolates possessing a polybasic ...

Diaz A, Enomoto S, Romagosa A, Sreevatsan S, Nelso. Genome plasticity of triple reassortant H1N1 influenza A virus during infection of vaccinated pigs. J Gen Virol. 2015 Aug 5. doi: 10.1099/jgv.  Abstract  
submitted by kickingbird at Aug, 10, 2015 from J Gen Virol. 2015 Aug 5. doi: 10.1099/jgv (via http://www.ncbi.nlm.nih.gov/pubmed/26251306)
To gain insights into the evolution of influenza A viruses (IAVs) during infection of vaccinated pigs, we experimentally infected a 3 week-old naive pig with a triple reassortant H1N1 IAV and placed him ...

Farrell PC, Hunter C, Truong B, Bunning M. Control of highly pathogenic avian influenza in Quang Tri province, Vietnam: voices from the human animal interface. Rural and Remote Health 15: 3044. (Online) 2015.  Abstract  
submitted by kickingbird at Aug, 7, 2015 from Rural and Remote Health 15: 3044. (Online) 2015 (via http://www.rrh.org.au/articles/subviewnew.asp?ArticleID=3044)
Highly pathogenic avian influenza (HPAI) is caused by the haemagglutinin 5, neuraminidase 1 (H5N1) influenza A virus. Around 80% of households in rural Vietnam raise poultry, which provides food security ...

Liu R, Leung RK-k, Chen T, Zhang X, Chen F, Chen S. The Effectiveness of Age-Specific Isolation Policies on Epidemics of Influenza A (H1N1) in a Large City in Central South China. PLoS ONE 10(7): e0132588. doi:10.1371/journal.pone.  Abstract  
submitted by kickingbird at Aug, 7, 2015 from PLoS ONE 10(7): e0132588. doi:10.1371/journal.pone (via http://journals.plos.org/plosone/article?id=10.1371/journal.)
During the early stage of a pandemic, isolation is the most effective means of controlling transmission. However, the effectiveness of age-specific isolation policies is not clear; especially little information ...

MI Nelson, DE Wentworth, SR Das. Evolutionary dynamics of influenza A viruses in US exhibition swine. J Infect Dis. (2015) doi:.  Abstract  
submitted by kickingbird at Aug, 7, 2015 from J Infect Dis. (2015) doi: (via http://jid.oxfordjournals.org/content/early/2015/08/03/infdi)
The role of exhibition swine in influenza A virus (IAVs) transmission was recently demonstrated by over 300 human infections of H3N2v viruses while attending agricultural fairs. Through active IAV surveillance ...

Leung YH, To MK, Lam TS, et al. Epidemiology of human influenza A(H7N9) infection in Hong Kong. J Microbiol Immunol Infect. 2015 Jun.  Abstract  
submitted by kickingbird at Aug, 5, 2015 from J Microbiol Immunol Infect. 2015 Jun (via http://www.e-jmii.com/article/S1684-1182(15)00772-0/fulltext)
Background/Purpose We conducted a case series study to review the epidemiology of human influenza A(H7N9) infection reported in Hong Kong. Methods We reviewed case records of confirmed human cases of ...

Yang ZF, Mok CK, Peiris JS, Zhong NS.. Human Infection with a Novel Avian Influenza A(H5N6) Virus. N Engl J Med 2015; 373:487-489.  Abstract  
submitted by kickingbird at Aug, 2, 2015 from N Engl J Med 2015; 373:487-489 (via http://www.nejm.org/doi/full/10.1056/NEJMc1502983)
Multiple reassortant strains of novel, highly pathogenic avian influenza A(H5) viruses in clade 2.3.4.4 have recently emerged and spread in Asia, Europe, and North America, giving rise to multiple subtypes ...

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