Sakai T, Takagi H, Muraki Y, Saito M, et al. Unique directional motility of influenza C virus controlled by its filamentous morphology and short-range motions. J Virol 2017 Nov 8. Abstract
submitted by kickingbird at Nov, 13, 2017 from J Virol 2017 Nov 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29118122/)
Influenza virus motility is based on cooperation between two viral spike proteins, hemagglutinin (HA) and neuraminidase (NA), and is a major determinant of virus infectivity. To translocate a virus particle ... Wong SS, Oshansky CM, Guo XJ, Ralston J, et al. Severe influenza is characterized by prolonged immune activation: results from the SHIVERS cohort study. J Infect Dis 2017 Nov 3. Abstract
submitted by kickingbird at Nov, 13, 2017 from J Infect Dis 2017 Nov 3 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29112724/)
Background: The immunologic factors underlying severe influenza are poorly understood. To address this, we compared the immune responses of influenza-confirmed hospitalized individuals with severe acute ... Kim MC, Lee YN, Kim YJ, Choi HJ, et al. Immunogenicity and efficacy of replication-competent recombinant influenza virus carrying multimeric M2 extracellular domains in a chimeric hemagglutinin conjugate. Antiviral Res 2017;148:43-52. Abstract
submitted by kickingbird at Nov, 13, 2017 from Antiviral Res 2017;148:43-52 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29107058/)
Current influenza vaccines provide hemagglutinin (HA) strain-specific protection. To improve cross protection, we engineered replication-competent influenza A virus to express tandem repeats of heterologous ... Pei JX, Qin JQ, Nong H, etc.,al. Genetic characterization of a highly pathogenic avian influenza A(H7N9) virus strain isolated in Nanning city. China Public Health. Abstract
submitted by kickingbird at Nov, 19, 2017 from China Public Health (via http://kns.cnki.net/kcms/detail/21.1234.R.20171020.1323.016.)
To analyze the traceability and genetic characteristics of a highly pathogenic H7N9 avian influenza virus strain isolated in Nanning city, 2017 through sequencing of HA and NA gene of the virus. Both HA ... Wohlgemuth N, Ye Y, Fenstermacher KJ, Liu H, et al. The M2 protein of live, attenuated influenza vaccine encodes a mutation that reduces replication in human nasal epithelial cells. Vaccine 2017 Oct 24. Abstract
submitted by kickingbird at Nov, 6, 2017 from Vaccine 2017 Oct 24 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29079099/)
The influenza A virus components of the live, attenuated influenza vaccine (LAIV) encode the HA and NA gene segments from a circulating virus strain and the remaining gene segments from the cold-adapted ... Yan J, Morrow MP, Chu JS, Racine T, et al. Broad cross-protective anti-hemagglutination responses elicited by influenza microconsensus DNA vaccine. Vaccine 2017 Oct 31. Abstract
submitted by kickingbird at Nov, 6, 2017 from Vaccine 2017 Oct 31 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29100705/)
Despite the routine development and distribution of seasonal influenza vaccines, influenza remains an important pathogen contributing to significant human morbidity as well as mortality each year. The ... Qi W, Jia W, Liu D, Li J, et al. Emergence and adaptation of a novel highly pathogenic H7N9 influenza virus in birds and humans from a 2013-human-infecting low pathogenic ancestor. J Virol 2017 Oct 25. Abstract
submitted by kickingbird at Nov, 6, 2017 from J Virol 2017 Oct 25 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29070694/)
Since its emergence in 2013, the H7N9 low pathogenic avian influenza virus (LPAIV) has been circulating in domestic poultry in China, causing five waves of human infections. Recently, a novel H7N9 highly ... Waring BM, Sjaastad LE, Fiege JK, Fay EJ, et al. microRNA-based attenuation of influenza virus across susceptible hosts. J Virol 2017 Nov 1. Abstract
submitted by kickingbird at Nov, 6, 2017 from J Virol 2017 Nov 1 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29093096/)
Influenza A virus drives significant morbidity and mortality in humans and livestock. Annual circulation of the virus in livestock and waterfowl contributes to severe economic disruption and increases ... Kirchenbaum GA, Allen JD, Layman TS, Sautto GA, et. Infection of Ferrets with Influenza Virus Elicits a Light Chain-Biased Antibody Response against Hemagglutinin. J Immunol 2017 Oct 27. Abstract
submitted by kickingbird at Nov, 6, 2017 from J Immunol 2017 Oct 27 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29079697/)
The domestic ferret (Mustela putorius furo) is a commonly used animal model for the study of influenza virus infection and vaccination. Recently, our group has developed murine mAbs with specificity for ... Gomaa MR, Kandeil A, El-Shesheny R, Shehata MM, et. Evidence of infection with avian, human, and swine influenza viruses in pigs in Cairo, Egypt. Arch Virol 2017 Oct 26. Abstract
submitted by kickingbird at Nov, 6, 2017 from Arch Virol 2017 Oct 26 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29075888/)
The majority of the Egyptian swine population was culled in the aftermath of the 2009 H1N1 pandemic, but small-scale growing remains. We sampled pigs from piggeries and an abattoir in Cairo. We found virological ... Moasser E, Behzadian F, Moattari A, Fotouhi F, et. Characterization of the neuraminidase genes from human influenza A viruses circulating in Iran from 2010 to 2015. Arch Virol 2017 Oct 31. Abstract
submitted by kickingbird at Nov, 6, 2017 from Arch Virol 2017 Oct 31 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29086107/)
BACKGROUND: Characterization of influenza viruses is critical for detection of new emerging variants. Herein, we analyzed the genetic diversity and drug susceptibility of the neuraminidase gene (NAs) ... Yu Z, Cheng K, Sun W, Zhang X, et al. PB2 and HA mutations increase the virulence of highly pathogenic H5N5 clade 2.3.4.4 avian influenza virus in mice. Arch Virol 2017 Oct 31. Abstract
submitted by kickingbird at Nov, 6, 2017 from Arch Virol 2017 Oct 31 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29090366/)
H5 clade 2.3.4.4 influenza A viruses pose a potential threat to public health and are a cause of public concern. Here, we generated mouse-adapted viruses of a waterfowl-origin H5N5 virus (H5 clade 2.3.4.4) ... Sarvestani ST, McAuley JL. The role of the NLRP3 inflammasome in regulation of antiviral responses to influenza A virus infection. Antiviral Res 2017 Oct 30. Abstract
submitted by kickingbird at Nov, 6, 2017 from Antiviral Res 2017 Oct 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29097227/)
The innate immune system provides the host with both a dynamic barrier to prevent infection and a means to which rapid anti-microbial responses can be mounted. The inflammasome pathway is a critical host ... Marathe BM, Mostafa HH, Vogel P, Pascua PNQ, et al. A pharmacologically immunosuppressed mouse model for assessing influenza B virus pathogenicity and oseltamivir treatment. Antiviral Res 2017 Oct 31. Abstract
submitted by kickingbird at Nov, 6, 2017 from Antiviral Res 2017 Oct 31 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29100887/)
Immunocompromised patients are highly susceptible to influenza virus infections. Although neuraminidase inhibitor (NAI) therapy has proved effective in these patients, the treatment regimens require optimization, ... Beerens N, Heutink R, Bergervoet SA, Harders F, Bo. Multiple Reassorted Viruses as Cause of Highly Pathogenic Avian Influenza A(H5N8) Virus Epidemic, the Netherlands, 2016. Emerg Infect Dis. 2017 Dec. Abstract
submitted by kickingbird at Nov, 4, 2017 from Emerg Infect Dis. 2017 Dec (via https://wwwnc.cdc.gov/eid/article/23/12/17-1062_article)
In 2016, an epidemic of highly pathogenic avian influenza A virus subtype H5N8 in the Netherlands caused mass deaths among wild birds, and several commercial poultry farms and captive bird holdings were ... Kleyheeg E, Slaterus R, Bodewes R, Rijks JM, Spier. Deaths among Wild Birds during Highly Pathogenic Avian Influenza A(H5N8) Virus Outbreak, the Netherlands. Emerg Infect Dis. 2017 Dec. Abstract
submitted by kickingbird at Nov, 4, 2017 from Emerg Infect Dis. 2017 Dec (via https://wwwnc.cdc.gov/eid/article/23/12/17-1086_article)
During autumn–winter 2016–2017, highly pathogenic avian influenza A(H5N8) viruses caused mass die-offs among wild birds in the Netherlands. Among the ≈13,600 birds reported dead, most were tufted ducks ... Xiangjun Du, etc.,al. Evolution-informed forecasting of seasonal influenza A (H3N2). Science Translational Medicine 25 Oct 2017. Abstract
submitted by kickingbird at Nov, 1, 2017 from Science Translational Medicine 25 Oct 2017 (via http://stm.sciencemag.org/content/scitransmed/9/413/eaan5325)
Interpandemic or seasonal influenza A, currently subtypes H3N2 and H1N1, exacts an enormous annual burden both in terms of human health and economic impact. Incidence prediction ahead of season remains ... Ana-Sosa-Batiz F, Johnston APR, Hogarth PM, Wines. Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults. Vaccine 2017 Oct 10. Abstract
submitted by kickingbird at Nov, 1, 2017 from Vaccine 2017 Oct 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29029940/)
Globally the most commonly utilised immunisation against influenza is the trivalent inactivated influenza vaccine (TIV) derived from an A/H1N1, an A/H3N2 and aB type influenza virus. Vaccine effectiveness ... Ortiz JR, Hombach J. Announcing the publication of the WHO immunological basis for immunization series module on influenza vaccines. Vaccine 2017 Oct 14. Abstract
submitted by kickingbird at Nov, 1, 2017 from Vaccine 2017 Oct 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29042200/)
In 2017, the World Health Organization (WHO) published a document aimed at facilitating influenza vaccine introduction and use in low- and middle-income countries. The document "The Immunological Basis ... Buffin S, Ikhelef N, Prudent J, Dubayle J, et al. A latex agglutination assay to quantify the amount of hemagglutinin protein in adjuvanted low-dose influenza monovalent vaccines. J Virol Methods 2017. Abstract
submitted by kickingbird at Nov, 1, 2017 from J Virol Methods 2017 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29030070/)
To formulate inactivated influenza vaccines, the concentration of hemagglutinin (HA) must be accurately determined. The standard test currently used to measure HA in influenza vaccines is the Single Radial ... 7513 items, 20/Page, Page[224/376][|<<] [|<] [221] [222] [223] [224] [225] [226] [227] [228] [229] [230] [>|] [>>|] |
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