Loebermann M, et al. A phase III, open-label, single-arm, study to evaluate the safety and immunogenicity of a trivalent, surface antigen inactivated subunit influenza virus vaccine produced in mammalian cell culture (Opt. Infection. 2018 Oct 8.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Infection. 2018 Oct 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30298473)
Vaccination is an essential tool in reducing the impact of seasonal influenza infections. The viral strains responsible for seasonal outbreaks vary annually, and preventive vaccines have to be adapted ... Lee N, Hurt AC. Neuraminidase inhibitor resistance in influenza: a clinical perspective. Curr Opin Infect Dis. 2018 Oct 6.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30299356)
PURPOSE OF REVIEW: Neuraminidase inhibitors (NAIs), including oseltamivir, zanamivir, and peramivir, is the main class of antiviral available for clinical use. As such, development of resistance toward ... Beigel JH. Polyclonal and monoclonal antibodies for the treatment of influenza. Curr Opin Infect Dis. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30299360)
PURPOSE OF REVIEW: This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials.RECENT ... Vanderbeke L, et al. Invasive pulmonary aspergillosis complicating severe influenza: epidemiology, diagnosis and treatment. Curr Opin Infect Dis. 2018 Oct 5. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30299367)
PURPOSE OF REVIEW: Bacterial superinfection of critically ill influenza patients is well-known, but in recent years, more and more reports describe invasive aspergillosis as a frequent complication as ... Li J, et al.. Continued reassortment of avian H6 influenza viruses from Southern China, 2014~2016. Transbound Emerg Dis. 2018 Oct 9.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30300968)
H6 subtype avian influenza virus (AIV) was prevalent in poultry and could sporadically infect humans. Here, a total of 196 novel H6 AIVs isolated from poultry in eight provinces of China from 2014 to 2016 ... Khurana S, et al. AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization. NPJ Vaccines. 2018 Oct 1;3:40.. Abstract
submitted by kickingbird at Oct, 15, 2018 from NPJ Vaccines. 2018 Oct 1;3:40. (via https://www.ncbi.nlm.nih.gov/pubmed/30302282)
Immune responses to inactivated vaccines against avian influenza are poor due in part to lack of immune memory. Adjuvants significantly increased virus neutralizing titers. We performed comprehensive analyses ... Li R, et al.. Tree shrew as a new animal model to study the pathogenesis of avian influenza (H9N2) virus infection. Emerg Microbes Infect. 2018 Oct 10;7(1):166.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Emerg Microbes Infect. 2018 Oct 10;7(1):166. (via https://www.ncbi.nlm.nih.gov/pubmed/30301950)
Outbreaks of avian influenza virus continue to pose threats to human health. Animal models such as the mouse, ferret, and macaque are used to understand the pathogenesis of avian influenza virus infection ... Van Hemert C, et., al. Survey of Arctic Alaskan Wildlife For Influenza A Antibodies: Limited Evidence For Exposure of Mammals. J Wildl Dis. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 11, 2018 from J Wildl Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30289331)
Influenza A viruses (IAVs) are maintained in wild waterbirds and have the potential to infect a broad range of species, including wild mammals. The Arctic Coastal Plain of Alaska supports a diverse suite ... Hagan RS, Torres-Castillo J, Doerschuk CM. Myeloid TBK1 Signaling Contributes to the Immune Response to Influenza. Am J Respir Cell Mol Biol. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 11, 2018 from Am J Respir Cell Mol Biol. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30290124)
Macrophages provide key elements of the host response to influenza A virus (IAV) infection, including expression of type I interferon (IFN) and inflammatory cytokines and chemokines. TANK-binding kinase ... Lee MS, Jang EY, Cho J, Kim K, Lee CH. Development and comparison of two H5N8 influenza A vaccine candidate strains. Arch Virol. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 11, 2018 from Arch Virol. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30291503)
Avian influenza viruses circulating in birds have caused outbreaks of infection in poultry and humans, thereby threatening public health. Recently, a highly pathogenic avian influenza (HPAI) virus (H5N8) ... Yu Z, Gao Y, He H, Zhao Y, Yuan X, Cheng K. Isolation and genetic characterization of H13N8 low pathogenic avian influenza virus from migratory birds in eastern China. Transbound Emerg Dis. 2018 Oct 6. Abstract
submitted by kickingbird at Oct, 11, 2018 from Transbound Emerg Dis. 2018 Oct 6 (via https://www.ncbi.nlm.nih.gov/pubmed/30291732)
Low pathogenic avian influenza virus (LPAIV) is an important zoonotic pathogen. Migratory birds are the natural reservoir for all 16 haemagglutinin (HA) and 9 neuraminidase (NA) subtypes of LPAIV. Surveillance ... Le TV, et., al. Fatal Avian Influenza A/H5N1 Infection in a 36-Week Pregnant Woman Survived by her Newborn - Soc Trang, Vietnam, 2012. Influenza Other Respir Viruses. 2018 Oct 6.. Abstract
submitted by kickingbird at Oct, 11, 2018 from Influenza Other Respir Viruses. 2018 Oct 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30291769)
Outbreaks of H5N1 Avian Influenza (AI) emerged in Indonesia, Thailand and Viet Nam during 2003- 2005. Its severe impact has been reported; the Food and Agriculture Organization (FAO) and World Bank (WB) ... Yamayoshi S, Yasuhara A, Ito M, Uraki R, Kawaoka Y. Differences in the ease with which mutant viruses escape from human monoclonal antibodies against the HA stem of influenza A virus. J Clin Virol. 2018 Sep 26;108:105-111. Abstract
submitted by kickingbird at Oct, 11, 2018 from J Clin Virol. 2018 Sep 26;108:105-111 (via https://www.ncbi.nlm.nih.gov/pubmed/30292135)
BACKGROUND: Broadly protective human monoclonal antibodies that recognize the conserved epitopes in the HA of influenza A virus are being developed as therapeutic agents. Emergence of resistant viruses ... Marchenko V, etc.,al. Isolation and characterization of H5Nx highly pathogenic avian influenza viruses of clade 2.3.4.4 in Russia. Virology. 2018 Oct 5;525:216-223. Abstract
submitted by kickingbird at Oct, 10, 2018 from Virology. 2018 Oct 5;525:216-223 (via https://www.ncbi.nlm.nih.gov/pubmed/30296682)
In 2016-2017, several subtypes of the highly pathogenic avian influenza (HPAI) virus were isolated on the territory of Russia. In the autumn of 2016, during the avian influenza virus surveillance in the ... Rodriguez-Lainz A, et.,al. Influenza vaccination coverage among US-Mexico land border crossers: 2009 H1N1 pandemic and 2011-2012 influenza season. Travel Med Infect Dis. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 10, 2018 from Travel Med Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30296482)
BACKGROUND: The high volume of US-Mexico land border crossings can facilitate international dissemination of influenza viruses.METHODS: We surveyed adult pedestrians crossing into the United States at ... Hill AT, et.,al. Adult Outpatients with Acute Cough due to Suspected Pneumonia or Influenza: CHEST Guideline and Expert Panel Report. Chest. 2018 Oct 5. Abstract
submitted by kickingbird at Oct, 10, 2018 from Chest. 2018 Oct 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30296418)
BACKGROUND: Patients commonly present to primary care services with upper and lower respiratory tract infections and guidelines to help clinicians investigate and treat acute cough due to suspected pneumonia ... Poon CM, Yi Wong EL, Chau PYK, Yau SY, Yeoh EK. Management decision of hospital surge: assessing seasonal upsurge in inpatient medical bed occupancy rate among public acute hospitals in Hong Kong.. QJM. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 10, 2018 from QJM. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30295857)
Background: There were recurrent upsurges in demand for public hospital services in Hong Kong. An understanding of the contribution of some possible factors for the rise in health care burden would help ... Haag R, et., al. Exploring rigid and flexible core trivalent sialosides for influenza virus inhibition. Chemistry. 2018 Oct 8.. Abstract
submitted by kickingbird at Oct, 10, 2018 from Chemistry. 2018 Oct 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30295350)
We describe the chemical synthesis and binding analysis of functionalizable rigid and flexible core trivalent sialosides bearing oligoethylene glycol (OEG) spacers interacting with spike proteins of influenza ... Kyaw WM, Chow A, Hein AA, Lee LT, Leo YS, Ho HJ. Factors influencing seasonal influenza vaccination uptake among health care workers in an adult tertiary care hospital in Singapore: A cross-sectional survey. Am J Infect Control. 2018 Oct 4. Abstract
submitted by kickingbird at Oct, 10, 2018 from Am J Infect Control. 2018 Oct 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30293741)
BACKGROUND: This study aimed to evaluate the factors influencing seasonal influenza vaccination uptake among different health care professional groups.METHODS: A single-center, cross-sectional survey using ... Hayden FG. et al. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 Sep 6;379(10):913-923. Abstract
submitted by kickingbird at Oct, 10, 2018 from N Engl J Med. 2018 Sep 6;379(10):913-923 (via https://www.nejm.org/doi/full/10.1056/NEJMoa1716197)
BackgroundBaloxavir marboxil is a selective inhibitor of influenza cap-dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains ... 8181 items, 20/Page, Page[220/410][|<<] [|<] [211] [212] [213] [214] [215] [216] [217] [218] [219] [220] [>|] [>>|] |
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