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Wei X, et al. The interaction of cellular protein ANP32A with influenza A virus polymerase component PB2 promotes vRNA synthesis. Arch Virol. 2019 Jan 21.  Abstract  
submitted by kickingbird at Jan, 27, 2019 from Arch Virol. 2019 Jan 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30666459)
The subunits PA, PB1, and PB2 of influenza A virus RNA polymerase are essential for efficient viral RNA synthesis and virus replication because of their role in recruiting multiple nuclear proteins. ANP32A ...

Wüthrich D, et al. Evaluation of two workflows for whole genome sequencing-based typing of influenza A viruses. J Virol Methods. 2019 Jan 21.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from J Virol Methods. 2019 Jan 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30677464)
We compared two sample preparation protocols for whole genome sequencing of influenza A viruses. Each protocol was assessed using cDNA quantity and quality and the resulting mean genome coverage after ...

Byrne-Nash RT, et al. A neuraminidase potency assay for quantitative assessment of neuraminidase in influenza vaccines. NPJ Vaccines. 2019 Jan 22;4:3.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from NPJ Vaccines. 2019 Jan 22;4:3 (via https://www.ncbi.nlm.nih.gov/pubmed/30675394)
Neuraminidase (NA) immunity leads to decreased viral shedding and reduced severity of influenza disease; however, NA content in influenza vaccines is currently not regulated, resulting in inconsistent ...

Wu H, et al. Generation of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) system. Sci Rep. 2019 Jan 23;9(1):366.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from Sci Rep. 2019 Jan 23;9(1):366 (via https://www.ncbi.nlm.nih.gov/pubmed/30675003)
To address the unmet needs for human polyclonal antibodies both as therapeutics and diagnostic reagents, building upon our previously established transchromosomic (Tc) cattle platform, we report herein ...

Ohkusa Y, et al. Inquiry into some gap among oseltamivir use and severe abnormal behavior in Japanese children and adolescents with influenza. Drug Discov Ther. 2018;12(6):381-383.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from Drug Discov Ther. 2018;12(6):381-383 (via https://www.ncbi.nlm.nih.gov/pubmed/30674775)
The Fukushima research has examined data form a cohort study of 10,000 Japanese children under 18 years old with influenza during three months to demonstrate that the relative risk of A-type abnormal behavior ...

Shibata A, et al. Characterization of a novel reassortant H7N3 highly pathogenic avian influenza virus isolated from a poultry meat product taken on a passenger flight to Japan. J Vet Med Sci. 2019 Jan 24.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from J Vet Med Sci. 2019 Jan 24 (via https://www.ncbi.nlm.nih.gov/pubmed/30674734)
A new reassortant H7N3 avian influenza virus (AIV) was isolated from a duck meat product that was illegally taken on board a passenger flight from China to Japan in March 2018. Sequencing analysis revealed ...

Salem E, et al. Pathogenesis, host innate immune response and aerosol transmission of Influenza D virus in cattle. J Virol. 2019 Jan 23..  Abstract  
submitted by kickingbird at Jan, 26, 2019 from J Virol. 2019 Jan 23. (via https://www.ncbi.nlm.nih.gov/pubmed/30674628)
The recently discovered influenza D virus (IDV) of the Orthomyxoviridae family has been detected in swine and ruminants with a worldwide distribution. Cattle are considered to be the primary host and reservoir ...

Machkovech HM, Bloom JD, Subramaniam AR. Comprehensive profiling of translation initiation in influenza virus infected cells. PLoS Pathog. 2019 Jan 23;15(1):e1007518.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from PLoS Pathog. 2019 Jan 23;15(1):e1007518 (via https://www.ncbi.nlm.nih.gov/pubmed/30673779)
Translation can initiate at alternate, non-canonical start codons in response to stressful stimuli in mammalian cells. Recent studies suggest that viral infection and anti-viral responses alter sites of ...

Takashita E, et al. Detection of influenza A(H3N2) viruses exhibiting reduced susceptibility to the novel cap-dependent endonuclease inhibitor baloxavir in Japan, December 2018. Euro Surveill. 2019 Jan;24(3)..  Abstract  
submitted by kickingbird at Jan, 26, 2019 from Euro Surveill. 2019 Jan;24(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30670142)
The novel cap-dependent endonuclease inhibitor baloxavir marboxil was approved for the treatment of influenza virus infection in Japan in February 2018. Two influenza A(H3N2) viruses carrying an I38T substitution ...

More S, et al. Long non-coding RNA PSMB8-AS1 regulates influenza virus replication. RNA Biol. 2019 Jan 22.  Abstract  
submitted by kickingbird at Jan, 26, 2019 from RNA Biol. 2019 Jan 22 (via https://www.ncbi.nlm.nih.gov/pubmed/30669933)
Long non-coding RNAs (lncRNAs) are a new arm of gene regulatory mechanism as discovered by sequencing techniques and follow-up functional studies. There are only few studies on lncRNAs as related to gene ...

Koutsakos M, Kedzierska K, Subbarao K. Immune Responses to Avian Influenza Viruses. J Immunol. 2019 Jan 15;202(2):382-391..  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Immunol. 2019 Jan 15;202(2):382-391. (via https://www.ncbi.nlm.nih.gov/pubmed/30617120)
Avian influenza A viruses (IAVs) naturally infect different avian species, and aquatic birds are their natural reservoir. Sporadically, avian IAVs can be transmitted to humans, and some, such as H5N1 and ...

Hatayama K, et al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2019 Mar;91(3):361-369..  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Med Virol. 2019 Mar;91(3):361-369. (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury due to the excessive inflammatory reaction, even with neuraminidase inhibitor use. The ...

Zhang J, et al. Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication. Virology. 2019 Jan 2;526:1-12..  Abstract  
submitted by kickingbird at Jan, 23, 2019 from Virology. 2019 Jan 2;526:1-12. (via https://www.ncbi.nlm.nih.gov/pubmed/30316042)
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying JNK and PI3K ...

Yang Y, et al. Comparison between human infections caused by highly and low pathogenic H7N9 avian influenza viruses in Wave Five: clinical and virological findings. J Infect. 2019 Jan 18.  Abstract  
submitted by kickingbird at Jan, 23, 2019 from J Infect. 2019 Jan 18 (via https://www.ncbi.nlm.nih.gov/pubmed/30664912)
OBJECTIVE: The newly emerged highly pathogenic (HP) H7N9 avian influenza virus during Wave Five has caused 28 human infections, while differences in disease severity between low pathogenic (LP)- and HP-H7N9 ...

Ni Luh Putu Indi Dharmayanti, et al. Attenuation of highly pathogenic avian influenza A(H5N1) viruses in Indonesia following the reassortment and acquisition of genes from low pathogenicity avian influenza A virus progenitors. Emerging Microbes & Infections vol 7,147 (2018).  Abstract  
submitted by kickingbird at Jan, 22, 2019 from Emerging Microbes & Infections vol 7,147 (2018) (via https://www.nature.com/articles/s41426-018-0147-5)
The highly pathogenic avian influenza (HPAI) A(H5N1) virus is endemic in Indonesian poultry and has caused sporadic human infection in Indonesia since 2005. Surveillance of H5N1 viruses in live bird markets ...

Cong Chen, Zuliang Liu, Liguo Liu, Yan Xiao, et al. Broad neutralizing activity of a human monoclonal antibody against H7N9 strains from 2013 to 2017. Emerging Microbes & Infections vol 7, 179 (2018).  Abstract  
submitted by kickingbird at Jan, 22, 2019 from Emerging Microbes & Infections vol 7, 179 (2018) (via https://www.nature.com/articles/s41426-018-0182-2)
H7N9 influenza virus has been circulating among humans for five epidemic waves since it was first isolated in 2013 in China. The recent increase in H7N9 infections during the fifth outbreak in China has ...

Liu Y, et al. Cross-lineage protection by human antibodies binding the influenza B hemagglutinin. Nat Commun. 2019 Jan 18;10(1):324..  Abstract  
submitted by kickingbird at Jan, 22, 2019 from Nat Commun. 2019 Jan 18;10(1):324. (via https://www.nature.com/articles/s41467-018-08165-y)
Influenza B viruses (IBV) drive a significant proportion of influenza-related hospitalisations yet are understudied compared to influenza A. Current vaccines target the head of the viral hemagglutinin ...

Bedford JG, O´Keeffe M, Reading PC, Wakim LM. Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection. PLoS One. 2019 Jan 16;14(1):e0210132.  Abstract  
submitted by kickingbird at Jan, 18, 2019 from PLoS One. 2019 Jan 16;14(1):e0210132 (via https://www.ncbi.nlm.nih.gov/pubmed/30650117)
Interferon-induced transmembrane protein 3 (IFITM3) is a potent antiviral protein that enhances cellular resistance to a variety of pathogens, including influenza virus. Classically defined as an interferon-stimulated ...

Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, et al. Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza. Virology. 2019 Jan 4;529:7-15.  Abstract  
submitted by kickingbird at Jan, 16, 2019 from Virology. 2019 Jan 4;529:7-15 (via https://www.ncbi.nlm.nih.gov/pubmed/30641481)
H9N2 avian influenza viruses (AIVs) were prevailing in chickens, causing great economic losses and public health threats. In this study, turkey herpesviruses (HVT) was cloned as an infectious bacterial ...

Parra-Rojas C, Messling VV, Hernandez-Vargas EA. Adjuvanted influenza vaccine dynamics. Sci Rep. 2019 Jan 11;9(1):73.  Abstract  
submitted by kickingbird at Jan, 15, 2019 from Sci Rep. 2019 Jan 11;9(1):73 (via https://www.ncbi.nlm.nih.gov/pubmed/30635599)
Adjuvanted influenza vaccines constitute a key element towards inducing neutralizing antibody responses in populations with reduced responsiveness, such as infants and elderly subjects, as well as in devising ...

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