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2024-5-5 8:27:54
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Kwon JH, et al. Different pathogenicity of two strains of clade 2.3.4.4c H5N6 highly pathogenic avian influenza viruses bearing different PA and NS gene in domestic ducks. Virology. 2019 Jan 15;530:11-18.  Abstract  
submitted by kickingbird at Feb, 14, 2019 from Virology. 2019 Jan 15;530:11-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30753976)
H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIVs) have been disseminated to wide geographic regions since 2014. In 2016, five distinct genotypes (C-1 to C-5) of clade 2.3.4.4c H5N6 ...

Zhao L,Zhang X,Wu Z,Huang K,Sun X,Chen H, Jin M. The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2. Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519..  Abstract  
submitted by kickingbird at Feb, 14, 2019 from Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519. (via https://www.ncbi.nlm.nih.gov/pubmed/30753994)
The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although ...

Zheng Z, Lu Y, Short KR, Lu J. One health insights to prevent the next HxNy viral outbreak: learning from the epidemiology of H7N9. BMC Infect Dis. 2019 Feb 11;19(1):138.  Abstract  
submitted by kickingbird at Feb, 14, 2019 from BMC Infect Dis. 2019 Feb 11;19(1):138 (via https://www.ncbi.nlm.nih.gov/pubmed/30744562)
BACKGROUND: With an increased incidence of viral zoonoses, there is an impetus to strengthen collaborations between public health, agricultural and environmental departments. This interdisciplinary cooperation, ...

Wan YH, et al. Genetic characteristic of hemagglutinin of avian influenza A (H7N9) virus in Guizhou Province in 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2.  Abstract  
submitted by kickingbird at Feb, 14, 2019 from Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2 (via https://www.ncbi.nlm.nih.gov/pubmed/30744302)
The number of H7N9 bird flu cases was high and the situation was grim in guizhou province in 2017. To understand the molecular characteristics of the hemagglutinin gene (HA) and the risk of human infection ...

Leung VK, et al. Annual report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza in 2016. Commun Dis Intell (2018). 2019 Feb 1;43..  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Commun Dis Intell (2018). 2019 Feb 1;43. (via https://www.ncbi.nlm.nih.gov/pubmed/30739429)
As part of its role in the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne ...

Bosco-Lauth AM, et al. Shedding of clade 2.3.4.4 H5N8 and H5N2 highly pathogenic avian influenza viruses in peridomestic wild birds in the U.S.. Transbound Emerg Dis. 2019 Feb 10.  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Transbound Emerg Dis. 2019 Feb 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30740920)
European starlings (Sturnus vulgaris), house sparrows (Passer domesticus) and rock pigeons (Columba livia) are all wild birds commonly found in large numbers in and around human dwellings and domestic ...

Wang R, et al. Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production. Autophagy. 2019 Feb 11..  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Autophagy. 2019 Feb 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30741586)
Influenza A virus can evade host innate immune response that is involved in several viral proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the host innate immunity remains ...

Olsen SJ, et al. Estimating Risk to Responders Exposed to Avian Influenza A H5 and H7 Viruses in Poultry, United States, 2014~2017. Emerg Infect Dis. 2019 May 17;25(5).  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Emerg Infect Dis. 2019 May 17;25(5) (via https://www.ncbi.nlm.nih.gov/pubmed/30741630)
In the United States, outbreaks of avian influenza H5 and H7 virus infections in poultry have raised concern about the risk for infections in humans. We reviewed the data collected during 2014-2017 and ...

Kanekiyo M, et al. Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nat Immunol. 2019 Feb 11.  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Nat Immunol. 2019 Feb 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30742080)
The present vaccine against influenza virus has the inevitable risk of antigenic discordance between the vaccine and the circulating strains, which diminishes vaccine efficacy. This necessitates new approaches ...

Vuichard-Gysin D, et al. Development and validation of clinical prediction models to distinguish influenza from other viruses causing acute respiratory infections in children and adults. PLoS One. 2019 Feb 11;14(2):e0212050.  Abstract  
submitted by kickingbird at Feb, 13, 2019 from PLoS One. 2019 Feb 11;14(2):e0212050 (via https://www.ncbi.nlm.nih.gov/pubmed/30742654)
Predictive models have been developed for influenza but have seldom been validated. Typically they have focused on patients meeting a definition of infection that includes fever. Less is known about how ...

Mohl G, et al. Novel influenza inhibitors designed to target PB1 interactions with host importin RanBP5. Antiviral Res. 2019 Feb 8..  Abstract  
submitted by kickingbird at Feb, 13, 2019 from Antiviral Res. 2019 Feb 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30742842)
In search of novel targets for influenza inhibitors, a site on PB1 was selected for its high conservation and probable interaction with a host protein, RanBP5, that is key to nuclear import of PB1, where ...

Kwa?nik M, et al. Genetic Analysis of the M Gene of Equine Influenza Virus Strains Isolated in Poland, in the Context of the Asian-like Group Formation. J Vet Res. 2018 Dec 31;62(4):405-412.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from J Vet Res. 2018 Dec 31;62(4):405-412 (via https://www.ncbi.nlm.nih.gov/pubmed/30729195)
Introduction: Traditionally, evolutionary analysis of equine influenza virus (EIV) is based on the HA gene. However, the specificity of the influenza virus enables the classification of viral strains into ...

Jin M, Jang Y, Seo T, Seo SH. Inactivated H5 Antigens of H5N8 Protect Chickens from Lethal Infections by the Highly Pathogenic H5N8 and H5N6 Avian Influenza Viruses. J Vet Res. 2018 Dec 31;62(4):413-420.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from J Vet Res. 2018 Dec 31;62(4):413-420 (via https://www.ncbi.nlm.nih.gov/pubmed/30729196)
Introduction: Highly pathogenic Asian H5-subtype avian influenza viruses have been found in poultry and wild birds worldwide since they were first detected in southern China in 1996. Extensive control ...

Fallah Mehrabadi MH, et al. Full-genome characterization and genetic analysis of a H9N2 virus in commercial broilers in Iran, 2017. Trop Anim Health Prod. 2019 Feb 7.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from Trop Anim Health Prod. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30729386)
Since 1998, Iran's poultry industry has faced several outbreaks of low pathogenic avian influenza H9N2. Tissue samples were collected from a broiler flock with respiratory symptoms in autumn 2017. After ...

Nelson MI, Souza C, et al. Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico. Emerg Infect Dis. 2019 Apr 17;25(4)..  Abstract  
submitted by kickingbird at Feb, 11, 2019 from Emerg Infect Dis. 2019 Apr 17;25(4). (via https://www.ncbi.nlm.nih.gov/pubmed/30730827)
The genetic diversity of influenza A viruses circulating in swine in Mexico complicates control efforts in animals and presents a threat to humans, as shown by influenza A(H1N1)pdm09 virus. To describe ...

Zhu H, et al. Absence of adaptive evolution is the main barrier against influenza emergence in horses in Asia despite frequent virus interspecies transmission from wild birds. PLoS Pathog. 2019 Feb 7;15(2):e1007531..  Abstract  
submitted by kickingbird at Feb, 11, 2019 from PLoS Pathog. 2019 Feb 7;15(2):e1007531. (via https://www.ncbi.nlm.nih.gov/pubmed/30731004)
Virus ecology and evolution play a central role in disease emergence. However, their relative roles will vary depending on the viruses and ecosystems involved. We combined field studies, phylogenetics ...

Nagy A, Ji?inec T, Ji?incová H, ?erníková L, et al. In silico re-assessment of a diagnostic RT-qPCR assay for universal detection of Influenza A viruses. Sci Rep. 2019 Feb 7;9(1):1630..  Abstract  
submitted by kickingbird at Feb, 11, 2019 from Sci Rep. 2019 Feb 7;9(1):1630. (via https://www.ncbi.nlm.nih.gov/pubmed/30733500)
The ongoing evolution of microbial pathogens represents a significant issue in diagnostic PCR/qPCR. Many assays are burdened with false negativity due to mispriming and/or probe-binding failures. Therefore, ...

Feng H, Yamashita M, da Silva Lopes TJ, et al. Injectable Excipients as Novel Influenza Vaccine Adjuvants. Front Microbiol. 2019 Jan 24;10:19.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from Front Microbiol. 2019 Jan 24;10:19 (via https://www.ncbi.nlm.nih.gov/pubmed/30733711)
Influenza outbreaks can be either seasonal or pandemic. Vaccination is an effective strategy to control influenza; however, the efficacy of the currently available inactivated influenza virus vaccines ...

Mosaad Z, et al. In silico thermodynamic stability of mammalian adaptation and virulence determinants in polymerase complex proteins of H9N2 virus. J Genet Eng Biotechnol. 2018 Dec;16(2):757-767.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from J Genet Eng Biotechnol. 2018 Dec;16(2):757-767 (via https://www.ncbi.nlm.nih.gov/pubmed/30733797)
The polymerase complex proteins (PB2, PB1, and PA) are responsible primarily for the replication of avian influenza virus and play an important role in virus virulence, mammalian adaptation, and interspecies ...

Chamberlain N, et al. Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics. Redox Biol. 2019 Jan 29;22:101129.  Abstract  
submitted by kickingbird at Feb, 11, 2019 from Redox Biol. 2019 Jan 29;22:101129 (via https://www.ncbi.nlm.nih.gov/pubmed/30735910)
Protein disulfide isomerases (PDI) are a family of redox chaperones that catalyze formation or isomerization of disulfide bonds in proteins. Previous studies have shown that one member, PDIA3, interacts ...

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