Kikawa C, Huddleston J, Loes AN, Turner SA, Lee J,. Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025. Virus Evol. 2025 Nov 3;11(1):veaf086. Abstract
submitted by kickingbird at Nov, 26, 2025 from Virus Evol. 2025 Nov 3;11(1):veaf086 (via https://academic.oup.com/ve/article/11/1/veaf086/8313343)
The hemagglutinin of human influenza virus evolves rapidly to erode neutralizing antibody immunity. Twice per year, new vaccine strains are selected with the goal of providing maximum protection against ... EFSA. Avian influenza in Europe: enhanced surveillance and strict biosecurity needed as detections surge. EFSA. Abstract
submitted by kickingbird at Nov, 26, 2025 from EFSA (via https://www.efsa.europa.eu/en/news/avian-influenza-europe-en)
Between 6 September and 14 November 2025, 1,443 detections of highly pathogenic avian influenza (HPAI) A(H5) viruses were reported in wild birds across 26 European countries – four times higher than the ... Tommy Tsan-Yuk Lam, Todd Davis. [preprint]Nomenclature updates to the hemagglutinin gene clade designations resulting from the continued evolution of high pathogenicity avian influenza A(H5) virus clades 2.3.2.1c and 2.3.4.4. https://doi.org/10.1101/2025.11.23.690055. Abstract
submitted by kickingbird at Nov, 25, 2025 from https://doi.org/10.1101/2025.11.23.690055 (via https://www.biorxiv.org/content/10.1101/2025.11.23.690055v1)
The evolutionary divergence of the A(H5) hemagglutinin (HA) gene of high pathogenicity avian influenza (HPAI) viruses (A/goose/Guangdong/96 lineage) was analyzed by phylogenetic and average pairwise distance ... Moreno A, Pongolini S, Merialdi G, Cattoli G, Terr. Inactivation of Influenza A Viruses (H1N1, H5N1) During Grana-Type Raw Milk Cheesemaking: Implications for Foodborne Transmission Risk. Viruses. 2025; 17(12):1535. Abstract
submitted by kickingbird at Nov, 25, 2025 from Viruses. 2025; 17(12):1535 (via https://www.mdpi.com/1999-4915/17/12/1535)
The detection of H5N1 highly pathogenic avian influenza virus (HPAIV) in lactating dairy cattle in the United States, with high viral titers in raw milk, has raised concerns about zoonotic transmission ... Li Z, Liu M, Yang J, Sun Q, Ye D, Zhou W, Du R, Ch. Generation and Characterization of a CE1-Modified mCherry-Expressing Influenza A Virus for In Vivo Imaging and Antiviral Drug Evaluation. Viruses. 2025; 17(12):1537. Abstract
submitted by kickingbird at Nov, 25, 2025 from Viruses. 2025; 17(12):1537 (via https://www.mdpi.com/1999-4915/17/12/1537)
Influenza reporter viruses are essential for studying viral infection dynamics and assessing antiviral drug efficacy. However, insertion of exogenous reporter genes can impair both viral replication and ... Pérez-Sánchez T, Báez JC, Johnstone C. Concern for Highly Pathogenic Avian Influenza Spillover into Cetaceans. Viruses. 2025; 17(12):1536. Abstract
submitted by kickingbird at Nov, 25, 2025 from Viruses. 2025; 17(12):1536 (via https://www.mdpi.com/1999-4915/17/12/1536)
Influenza A virus (IAV) has a wide range of avian and mammalian hosts, leading to disease outbreaks and increasing the risk of panzootics and pandemics. Subtype H5N1 of clade 2.3.4.4b is causing the current ... Majumdar, D., Hann, E., Short, K.R. et al. Genetic strategies for avian influenza resilience in poultry: from host-pathogen interaction studies to precision breeding. Funct Integr Genomics 25, 252 (2025). Abstract
submitted by kickingbird at Nov, 25, 2025 from Funct Integr Genomics 25, 252 (2025) (via https://link.springer.com/article/10.1007/s10142-025-01777-w)
Avian influenza virus (AIV) remains a persistent threat to global poultry production and public health, owing to its ability to infect a wide range of avian and mammalian species. The global resurgence ... Davis M, Sun M, Solà E, Guo J, Valainis J, Shankar. [preprint]Young children have limited mucosal immunity when stimulated with an influenza vaccine in tonsil organoids. Res Sq [Preprint]. 2025 Oct 30:rs.3.rs-7842732. Abstract
submitted by kickingbird at Nov, 25, 2025 from Res Sq [Preprint]. 2025 Oct 30:rs.3.rs-7842732 (via https://www.researchsquare.com/article/rs-7842732/v1)
While it has been known for many years that children under five years old are much more vulnerable to most infectious diseases than older children or adults, we know very little about the specific immunological ... Yu W, He X, Zhao J, Dou Y, Hu T, Chen X, Ma X, Wan. Direct airway delivery of a humanized anti-H7N9 neutralizing antibody broadly protects against divergent H7 influenza viruses in the mouse model. J Virol. 2025 Nov 24:e0132725. Abstract
submitted by kickingbird at Nov, 25, 2025 from J Virol. 2025 Nov 24:e0132725 (via https://journals.asm.org/doi/10.1128/jvi.01327-25)
Passive administration of broadly neutralizing anti-influenza monoclonal antibodies (mAbs) before or after virus infection can prevent or alleviate disease. Unlike seasonal influenza, infection with zoonotic ... Benjamin C. Mollett, etc.,al. [preprint]Disease ecology and zoonotic risk of clade 2.3.4.4b H5N1 high pathogenicity avian influenza in the sub-Antarctic region. https://doi.org/10.21203/rs.3.rs-8029950/v1. Abstract
submitted by kickingbird at Nov, 23, 2025 from https://doi.org/10.21203/rs.3.rs-8029950/v1 (via https://www.researchsquare.com/article/rs-8029950/v1)
High pathogenicity avian influenza virus (HPAIV) has significantly impacted upon avian and mammalian populations across the Antarctic region. All viruses detected have been genotype B3.2 with phylogenetic ... DG Health and Food Safety. HPAI - Disease situation in the EU. European Commission. Abstract
submitted by kickingbird at Nov, 23, 2025 from European Commission (via https://food.ec.europa.eu/document/download/afc16941-1b3f-4c)
EU Member States:1052 outbreaks in wild birds in 23 Member States549 outbreaks in poultry confirmed in 19 Member States23.2 million poultry in the outbreak establishments (dead or culled)in certain areas, ... Luo, P., Li, K., Xie, Y. et al. Predictive modeling & mechanistic validation of synergistic pimodivir combinations for anti-influenza therapy via PB2cap affinity boost. npj Digit. Med. 8, 712 (2025). Abstract
submitted by kickingbird at Nov, 23, 2025 from npj Digit. Med. 8, 712 (2025) (via https://link.springer.com/article/10.1038/s41746-025-02083-2)
This study introduces a machine learning framework to predict effective antiviral combinations for influenza A. It identifies Pimodivir with Epinephrine or L-Adrenaline as synergistic agents, confirmed ... Alkubaisi NA, Aziz IM, Farrag MA, Aljowaie RM, Als. Evolution and Vaccine Strain Match of HA and NA Genes of Influenza A/H3N2 Subtype in Riyadh, Saudi Arabia, 2020~2023. Vaccines. 2025; 13(12):1184. Abstract
submitted by kickingbird at Nov, 23, 2025 from Vaccines. 2025; 13(12):1184 (via https://www.mdpi.com/2076-393X/13/12/1184)
Background/Objectives: Although several studies have shed light on the epidemiology of the influenza A/H3N2 subtype in Saudi Arabia, the knowledge regarding the molecular epidemiology and genetic diversity ... Lin J, Li Y, Luo H, Wang Y, Liu Y, Mei K, Wen F, L. Epidemiological Investigation and Characterization of Avian Influenza A H3N8 Virus in Guangdong Province, China. Animals. 2025; 15(23):3377. Abstract
submitted by kickingbird at Nov, 23, 2025 from Animals. 2025; 15(23):3377 (via https://www.mdpi.com/2076-2615/15/23/3377)
The H3N8 low pathogenic avian influenza virus (LPAIV) exhibits broad host tropism, infecting diverse avian and mammalian species, raising concerns about its zoonotic potential. Following the emergence ... Koutsakos M, Parry RH, Wille M. Mounting Evidence for an Expanded Host Range of Influenza B Viruses. Viruses. 2025; 17(12):1528. Abstract
submitted by kickingbird at Nov, 23, 2025 from Viruses. 2025; 17(12):1528 (via https://www.mdpi.com/1999-4915/17/12/1528)
Influenza B viruses (IBV) belong to the family of Orthomyxoviridae and circulate annually in humans causing respiratory illness. Although they are considered an exclusively human pathogen, there is evidence ... Kaituo Liu, Xiyue Wang, Yijia Sun, Xiaoquan Wang. Will avian influenza virus (H10N3) cause a major public health threat?. Animals and Zoonoses. Abstract
submitted by kickingbird at Nov, 23, 2025 from Animals and Zoonoses (via https://www.sciencedirect.com/science/article/pii/S295024892)
Avian influenza viruses (AIVs) cause significant economic losses to the poultry industry and pose a persistent threat to public health due to their capacity for cross-species infection of mammals and humans. ... Liu S, Sun Y, Peng Y, Xu C, Song S, Yan L. Cellular hnRNP AB inhibits avian influenza virus RNA synthesis via blocking UAP56-mediated nuclear export of PB2 mRNA. Vet Res. 2025 Nov 21;56(1):223. Abstract
submitted by kickingbird at Nov, 23, 2025 from Vet Res. 2025 Nov 21;56(1):223 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Avian influenza viral ribonucleoproteins (vRNPs) complete genome transcription and replication by interacting with host proteins, and RNA-dependent RNA polymerase (RdRp) is its major component. PB2 is ... de Rooij AJH, Lempers VJC, Park Y, Vicic N, Han AX. Reproducible and later vaccine strain selection can improve vaccine match to A/H3N2 seasonal influenza viruses. NPJ Vaccines. 2025 Nov 21;10(1):243. Abstract
submitted by kickingbird at Nov, 23, 2025 from NPJ Vaccines. 2025 Nov 21;10(1):243 (via https://www.nature.com/articles/s41541-025-01292-w)
Twice per year, the World Health Organization (WHO) recommends strains for seasonal influenza vaccines to ensure vaccine strains match circulating viruses. However, new variants can emerge after vaccine ... Neusser J, Zierer A, Riedl A, Javanmardi J, Rubio-. High-Resolution Wastewater-Based Surveillance of Three Influenza Seasons (2022-2025) Reveals Distinct Seasonal Patterns of Viral Activity in Munich, Germany. Microorganisms. 2025; 13(11):2630. Abstract
submitted by kickingbird at Nov, 21, 2025 from Microorganisms. 2025; 13(11):2630 (via https://www.mdpi.com/2076-2607/13/11/2630)
In the Northern Hemisphere, annual waves of influenza disease with varying degrees of spread and severity are observed each winter. With wastewater-based surveillance (WBS), including both centralized ... Rashid M-u, Yasmin T, Coombs KM. HSPA5, a Host Cellular Heat-Shock Protein Required for Influenza a Virus Replication. International Journal of Molecular Sciences. 2025;. Abstract
submitted by kickingbird at Nov, 21, 2025 from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/22/10998)
The Influenza A Virus (IAV) is known to hijack cellular proteins during its replication. IAV infection increases the expression of Heat-shock-protein family A (Hsp70) member 5 (HSPA5) in human cells, but ... 9808 items, 20/Page, Page[17/491][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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