Van Poelvoorde LAE, Saelens X, Thomas I, Roosen NH. Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza. Trends Biotechnol. 2019 Dec. Abstract
submitted by kickingbird at Dec, 10, 2019 from Trends Biotechnol. 2019 Dec (via https://www.cell.com/trends/biotechnology/fulltext/S0167-779)
Next-generation sequencing (NGS) can enable a more effective response to a wide range of communicable disease threats, such as influenza, which is one of the leading causes of human morbidity and mortality ... van de Sandt CE, et al. Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph. Nat Commun. 2019 Dec 6;10(1):557. Abstract
submitted by kickingbird at Dec, 10, 2019 from Nat Commun. 2019 Dec 6;10(1):557 (via https://www.nature.com/articles/s41467-019-13346-4)
Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease are largely unknown. As the HLA-A*68:01 allele can be linked to severe pandemic ... Xu C, Shu Y. The heterogeneity of influenza seasonality by subtype and lineage in China. J Infect. 2019 Nov 29.. Abstract
submitted by kickingbird at Dec, 8, 2019 from J Infect. 2019 Nov 29. (via https://www.journalofinfection.com/article/S0163-4453(19)303)
Recently, a notable pattern of synchrony of influenza A and B virus, and respiratory syncytial virus incidence peaks globally was reported in this journal. A previous study characterized seasonal pattern ... Dellicour S, et al. Incorporating heterogeneous sampling probabilities in continuous phylogeographic inference - application to H5N1 spread in the Mekong region. Bioinformatics. 2019 Dec 2. Abstract
submitted by kickingbird at Dec, 8, 2019 from Bioinformatics. 2019 Dec 2 (via https://www.ncbi.nlm.nih.gov/pubmed/31790143)
MOTIVATION: The potentially low precision associated with the geographic origin of sampled sequences represents an important limitation for spatially-explicit (i.e. continuous) phylogeographic inference ... Loh L, Koutsakos M, Kedzierska K, Hinks TSC. Influenza A Virus-Infected Lung Epithelial Cell Co-Culture with Human Peripheral Blood Mononuclear Cells. Methods Mol Biol. 2020;2098:141-147. Abstract
submitted by kickingbird at Dec, 8, 2019 from Methods Mol Biol. 2020;2098:141-147 (via https://www.ncbi.nlm.nih.gov/pubmed/31792820)
Sensing of influenza A virus (IAV) infection by pattern recognition receptors can occur by either direct infection of lung epithelial cells or uptake of virus-infected cells by innate cells such as dendritic ... Njouom R, et al. Circulation of influenza virus from 2009 to 2018 in Cameroon: 10 years of surveillance data. PLoS One. 2019 Dec 3;14(12):e0225793.. Abstract
submitted by kickingbird at Dec, 8, 2019 from PLoS One. 2019 Dec 3;14(12):e0225793. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since the recent emergence of several subtypes of influenza viruses with pandemic potentials, there has been growing interest on the control of this infection worldwide. This study aimed to describe the ... Zhou Y, Li S, Bi S, Li N, Bi Y, Liu W, Wang B. Long-lasting protective immunity against H7N9 infection is induced by intramuscular or CpG-adjuvanted intranasal immunization with the split H7N9 vaccine. Int Immunopharmacol. 2019 Dec 2:106013.. Abstract
submitted by kickingbird at Dec, 8, 2019 from Int Immunopharmacol. 2019 Dec 2:106013. (via https://www.sciencedirect.com/science/article/pii/S156757691)
There is an urgent need for efficient vaccines against the highly pathogenic avian influenza A viral strain H7N9. The duration and intensity of the immune response to H7N9 critically impacts the epidemiology ... Pascua PNQ, et al. Influenza B viruses from different genetic backgrounds are variably impaired by neuraminidase inhibitor resistance-associated substitutions. Antiviral Res. 2019 Nov 29:104669.. Abstract
submitted by kickingbird at Dec, 7, 2019 from Antiviral Res. 2019 Nov 29:104669. (via https://www.sciencedirect.com/science/article/pii/S016635421)
Identifying evolutionary routes to antiviral resistance among influenza viruses informs molecular-based resistance surveillance and clinical decisions. To improve antiviral management and understand whether ... Imai M, et al. Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets. Nat Microbiol. 2019 Nov 25.. Abstract
submitted by kickingbird at Dec, 7, 2019 from Nat Microbiol. 2019 Nov 25. (via https://www.nature.com/articles/s41564-019-0609-0)
Here we report the isolation of the influenza A/H1N1 2009 pandemic (A/H1N1pdm) and A/H3N2 viruses carrying an I38T mutation in the polymerase acidic protein-a mutation that confers reduced susceptibility ... Bogdanow B, et al. The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant. Nat Commun. 2019 Dec 4;10(1):5518. Abstract
submitted by kickingbird at Dec, 7, 2019 from Nat Commun. 2019 Dec 4;10(1):5518 (via https://www.nature.com/articles/s41467-019-13520-8)
Pandemic influenza A virus (IAV) outbreaks occur when strains from animal reservoirs acquire the ability to infect and spread among humans. The molecular basis of this species barrier is incompletely understood. ... Chiapponi C, et al. Detection of a New Genetic Cluster of Influenza D Virus in Italian Cattle. Viruses. 2019 Nov 30;11(12).. Abstract
submitted by kickingbird at Dec, 7, 2019 from Viruses. 2019 Nov 30;11(12). (via https://www.mdpi.com/1999-4915/11/12/1110)
Influenza D virus (IDV) has been increasingly reported all over the world. Cattle are considered the major viral reservoir. Based on the hemagglutinin-esterase (HEF) gene, three main genetic and antigenic ... Zhong G, et al. Mutations in the NA-like protein of bat influenza H18N11 virus enhance virus replication in mammalian cells, mice, and ferrets. J Virol. 2019 Dec 4. Abstract
submitted by kickingbird at Dec, 7, 2019 from J Virol. 2019 Dec 4 (via https://jvi.asm.org/content/early/2019/11/28/JVI.01416-19)
To characterize bat influenza H18N11 virus, we propagated a reverse genetics-generated H18N11 virus in MDCK II cells and detected two adapting mutations in the neuraminidase (NA)-like protein (NA-F144C ... Valesano AL, et al. Influenza B viruses exhibit lower within-host diversity than influenza A viruses in human hosts. J Virol. 2019 Dec 4. Abstract
submitted by kickingbird at Dec, 7, 2019 from J Virol. 2019 Dec 4 (via https://jvi.asm.org/content/early/2019/11/28/JVI.01710-19)
Influenza B virus undergoes seasonal antigenic drift more slowly than influenza A, but the reasons for this difference are unclear. While the evolutionary dynamics of influenza viruses play out globally, ... Shi L, et al. Molecular evolution and amino acid characteristics of newly isolated H9N2 avian influenza viruses from Liaoning Province, China. J Vet Med Sci. 2019 Dec 4.. Abstract
submitted by kickingbird at Dec, 7, 2019 from J Vet Med Sci. 2019 Dec 4. (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_19)
H9N2 is widespread among poultry and humans. Though this subtype is not lethal to either species, it can cause considerable financial losses for farmers and threaten human health. In this study, 10 new ... Chowdhury S, et al. The Pattern of Highly Pathogenic Avian Influenza H5N1 Outbreaks in South Asia. Trop Med Infect Dis. 2019 Nov 27;4(4).. Abstract
submitted by kickingbird at Dec, 2, 2019 from Trop Med Infect Dis. 2019 Nov 27;4(4). (via https://www.mdpi.com/2414-6366/4/4/138)
Highly pathogenic avian influenza (HPAI) H5N1 has caused severe illnesses in poultry and in humans. More than 15,000 outbreaks in domestic birds from 2005 to 2018 and 861 human cases from 2003 to 2019 ... Ilyushina NA, et al. Influenza A virus hemagglutinin mutations associated with use of neuraminidase inhibitors correlate with decreased inhibition by anti-influenza antibodies. Virol J. 2019 Nov 29;16(1):149. Abstract
submitted by kickingbird at Dec, 2, 2019 from Virol J. 2019 Nov 29;16(1):149 (via https://www.ncbi.nlm.nih.gov/pubmed/31783761)
BACKGROUND: Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such ... Mastrolia MV, Rubino C, Resti M, Trapani S, Galli. Characteristics and outcome of influenza-associated encephalopathy/encephalitis among children in a tertiary pediatric hospital in Italy, 2017-2019. BMC Infect Dis. 2019 Nov 29;19(1):1012. Abstract
submitted by kickingbird at Dec, 2, 2019 from BMC Infect Dis. 2019 Nov 29;19(1):1012 (via https://www.ncbi.nlm.nih.gov/pubmed/31783806)
BACKGROUND: Influenza is the most frequent cause of acute upper respiratory tract infections during winter season. Although rare, neurological manifestations are known to occur during influenza infection ... Hibbs BF, et al. Reports of atypical shoulder pain and dysfunction following inactivated influenza vaccine, Vaccine Adverse Event Reporting System (VAERS), 2010-2017. Vaccine. 2019 Nov 26.. Abstract
submitted by kickingbird at Dec, 2, 2019 from Vaccine. 2019 Nov 26. (via https://www.ncbi.nlm.nih.gov/pubmed/31784231)
BACKGROUND: Vaccines administered into or too close to underlying joint structures have the potential to cause shoulder injuries. Limited data exist on the epidemiology of such events.OBJECTIVE: To describe ... Zhang Y, Yu T, Ding Y, Li Y, Lei J, Hu B, Zhou J. Analysis of Expression Profiles of Long Noncoding RNAs and mRNAs in A549 Cells Infected with H3N2 Swine Influenza Virus by RNA Sequencing. Virol Sin. 2019 Nov 27.. Abstract
submitted by kickingbird at Dec, 1, 2019 from Virol Sin. 2019 Nov 27. (via https://www.ncbi.nlm.nih.gov/pubmed/31777011)
Long noncoding RNAs (lncRNAs) participate in regulating many biological processes. However, their roles in influenza A virus (IAV) pathogenicity are largely unknown. Here, we analyzed the expression profiles ... Oliva J, et al. A murine model for the study of influenza D virus. J Virol. 2019 Nov 27.. Abstract
submitted by kickingbird at Dec, 1, 2019 from J Virol. 2019 Nov 27. (via https://jvi.asm.org/content/early/2019/11/21/JVI.01662-19)
A novel genus within the Orthomyxoviridae family was identified in the USA and named Influenza D virus (IDV). Bovine have been proposed to be the primary host and three main viral lineages (D/OK-like, ... 8181 items, 20/Page, Page[164/410][|<<] [|<] [161] [162] [163] [164] [165] [166] [167] [168] [169] [170] [>|] [>>|] |
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