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2024-11-27 8:42:11
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Wang Y, Zhong W, Salam A, Tarning J, Zhan Q, Huang. Phase 2a, open-label, dose-escalating, multi-center pharmacokinetic study of favipiravir (T-705) in combination with oseltamivir in patients with severe influenza. EBioMedicine. 2020 Nov 21;62:103125.  Abstract  
submitted by kickingbird at Nov, 26, 2020 from EBioMedicine. 2020 Nov 21;62:103125 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data are also needed to determine dosage selection for favipiravir trials ...

Li X, Liang Z, Gan J, Lu L.. Epidemic situation of the complex seasonality of imported Influenza A and B virus transmission in Guangxi ports of China. Turk J Med Sci. 2020 Nov 25.  Abstract  
submitted by kickingbird at Nov, 26, 2020 from Turk J Med Sci. 2020 Nov 25 (via https://pubmed.ncbi.nlm.nih.gov/33237658/)
Background/aim: Analysis of the characteristics of influenza virus in imported cases in Guangxi Province of China.Methods: Throat swabs of imported cases with influenza-like symptoms were detected by real-time ...

Zhu G, Kang M, Wei X, Tang T, Liu T, Xiao J, Song. Different intervention strategies toward live poultry markets against avian influenza A (H7N9) virus: model-based assessment. Environ Res. 2020 Nov 18:110465.  Abstract  
submitted by kickingbird at Nov, 24, 2020 from Environ Res. 2020 Nov 18:110465 (via https://www.sciencedirect.com/science/article/abs/pii/S00139)
Background: Different interventions targeting live poultry markets (LPMs) are applied in China for controlling avian influenza A (H7N9), including LPM closure and "1110" policy (i.e., daily cleaning, weekly ...

Qian Z, Shou-Yu G, Feng-Xia Z, Peng Y, Wen-Jian S,. Molecular characteristics of H9N2 influenza viruses isolated from farmed raccoon dogs and arctic foxes in China. Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0.  Abstract  
submitted by kickingbird at Nov, 24, 2020 from Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
In this study, eight H9N2 IAVs were isolated from infected diseased, farmed raccoon dogs and arctic foxes. Eight genes shared 98.6%-100% identity among the isolates possessing a PSRSSR/GL motif at the ...

Qi Y, Wang H, Guo W, Liu C, Zhao L, Gu Y, Li S, Ch. Surveillance of multiple subtype specific antibodies against avian influenza viruses among egg yolk in wild ducks from northeast China, 2017~2019. Microb Pathog. 2020 Nov 18:104618.  Abstract  
submitted by kickingbird at Nov, 24, 2020 from Microb Pathog. 2020 Nov 18:104618 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Over the past decade, various avian influenza viruses have been isolated from wild ducks found in the northeast of China. To monitor the prevalence of multiple subtype specific AIVs antibodies, 1705 wild ...

Carrique L, Fan H, Walker AP, Keown JR, Sharps J,. Host ANP32A mediates the assembly of the influenza virus replicase. Nature. 2020 Nov 18.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Nature. 2020 Nov 18 (via https://www.nature.com/articles/s41586-020-2927-z)
Aquatic birds represent a vast reservoir from which new pandemic influenza A viruses can emerge1. Influenza viruses contain a negative-sense segmented RNA genome that is transcribed and replicated by the ...

Chung DH, Gomez DR, Vargas JM, Amador BL, Torchett. Low Pathogenicity Avian Influenza (H5N2) Viruses, Dominican Republic. Emerg Infect Dis. 2020 Dec;26(12):3094-3096.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Emerg Infect Dis. 2020 Dec;26(12):3094-3096 (via https://wwwnc.cdc.gov/eid/article/26/12/20-0268_article)
Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Whole-genome sequencing and phylogenetic analysis show introduction of an ...

Bravo-Vasquez N, Yao J, Jimenez-Bluhm P, Meliopoul. Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile. Emerg Infect Dis. 2020 Dec;26(12):2887-2898.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Emerg Infect Dis. 2020 Dec;26(12):2887-2898 (via https://wwwnc.cdc.gov/eid/article/26/12/20-2063_article)
Since their discovery in the United States in 1963, outbreaks of infection with equine influenza virus (H3N8) have been associated with serious respiratory disease in horses worldwide. Genomic analysis ...

Jiang Y, Ye Z, Chen D, Shu Y. Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort. Emerg Microbes Infect . 2020 Nov 20;1-0.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Emerg Microbes Infect . 2020 Nov 20;1-0 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Objectives The present study aimed to evaluate the real-world effectiveness of receiving both influenza and pneumococcal vaccines among Chinese elderly, the evidence on which has been sparse by far. Methods ...

Liu Y, Wang Y, Liu B, Cong X, Ji Y, Guo X, Gao Y. Phylogenetic analysis and clinical characteristics of the co-occurring mutations in HA and NA genes of influenza A(H1N1)pdm09 viruses during 2015-2017 in Beijing, China. Virol J. 2020 Nov 19;17(1):182..  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Virol J. 2020 Nov 19;17(1):182. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza A(H1N1)pdm09 viruses have undergone rapid evolution, and in recent years the complementary and antagonistic effects of HA and NA have gathered more attentions; however, the effects ...

Melidou A, Pereyaslov D, Hungnes O, Prosenc K, Alm. Virological surveillance of influenza viruses in the WHO European Region in 2019/20 - impact of the COVID-19 pandemic. Euro Surveill. 2020 Nov;25(46).  Abstract  
submitted by kickingbird at Nov, 22, 2020 from Euro Surveill. 2020 Nov;25(46) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
The COVID-19 pandemic negatively impacted the 2019/20 WHO European Region influenza surveillance. Compared with previous 4-year averages, antigenic and genetic characterisations decreased by 17% (3,140 ...

Yu J, Li F, Wang D. The first decade of research advances in influenza D virus. J Gen Virol. 2020 Nov 19.  Abstract  
submitted by kickingbird at Nov, 22, 2020 from J Gen Virol. 2020 Nov 19 (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
From its initial isolation in the USA in 2011 to the present, influenza D virus (IDV) has been detected in cattle and swine populations worldwide. IDV has exceptional thermal and acid stability and a broad ...

Nasamran C, Janetanakit T, Chiyawong S, Boonyapisi. Persistence of pdm2009-H1N1 internal genes of swine influenza in pigs, Thailand. Sci Rep. 2020 Nov 16;10(1):19847.  Abstract  
submitted by kickingbird at Nov, 19, 2020 from Sci Rep. 2020 Nov 16;10(1):19847 (via https://www.nature.com/articles/s41598-020-76771-2)
Swine influenza is one of the important zoonotic diseases of pigs. We conducted a longitudinal survey of swine influenza A viruses (S-IAV) circulating in a pig farm with history of endemic S-IAV infection ...

Chastagner A, Hervé S, Quéguiner S, Hirchaud E, Lu. Genetic and Antigenic Evolution of European Swine Influenza A Viruses of HA-1C (Avian-Like) and HA-1B (Human-Like) Lineages in France from 2000 to 2018. Viruses. 2020 Nov 13;12(11):E1304.  Abstract  
submitted by kickingbird at Nov, 19, 2020 from Viruses. 2020 Nov 13;12(11):E1304 (via https://www.mdpi.com/1999-4915/12/11/1304)
This study evaluated the genetic and antigenic evolution of swine influenza A viruses (swIAV) of the two main enzootic H1 lineages, i.e., HA-1C (H1av) and -1B (H1hu), circulating in France between 2000 ...

Amal EB, Saadi N, Asma F, Moncef B, Ouafae FF. Characterization and Phylogenetic Analysis of the Hemagglutinin Gene in H9 Influenza Viruses from Chickens in Morocco from 2017 to 2019. Avian Dis. 2020 Sep 1;64(3):310-314.  Abstract  
submitted by kickingbird at Nov, 19, 2020 from Avian Dis. 2020 Sep 1;64(3):310-314 (via https://bioone.org/journals/avian-diseases/volume-64/issue-3)
Since the early 2000s, the avian influenza virus (AIV) subtype H9N2 has been widely circulating in North African countries, including Libya, Tunisia, and Egypt. For unknown reasons, H9N2 was not detected ...

Abhijeet A Bakre, et al. Molecular epidemiology and glycomics of swine influenza viruses circulating in commercial swine farms in the southeastern and midwest United States. Vet Microbiol . 2020 Oct 31;251:108914.  Abstract  
submitted by kickingbird at Nov, 16, 2020 from Vet Microbiol . 2020 Oct 31;251:108914 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Tracking the genetic diversity and spread of swine influenza viruses (SIVs) in commercial swine farms is central for control and to reduce the potential emergence of SIV reassortants. We analyzed the diversity ...

Carre?o JM, McDonald JU, Hurst T, Rigsby P, Atkins. Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies. Vaccines (Basel). 2020 Nov 9;8(4):E666.  Abstract  
submitted by kickingbird at Nov, 16, 2020 from Vaccines (Basel). 2020 Nov 9;8(4):E666 (via https://www.mdpi.com/2076-393X/8/4/666)
The stalk domain of the hemagglutinin has been identified as a target for induction of protective antibody responses due to its high degree of conservation among numerous influenza subtypes and strains. ...

Tian X, Landreth S, Lu Y, Pandey K, Zhou Y. A Replication-Defective Influenza Virus Harboring H5 and H7 Hemagglutinins Provides Protection against H5N1 and H7N9 Infection in Mice. J Virol. 2020 Nov 11:JVI.02154-20.  Abstract  
submitted by kickingbird at Nov, 13, 2020 from J Virol. 2020 Nov 11:JVI.02154-20 (via https://jvi.asm.org/content/early/2020/11/06/JVI.02154-20)
The recent highly pathogenic avian influenza (HPAI) H5N1 and H7N9 viruses have caused hundreds of human infections with high mortality rates. Although H5N1 and H7N9 viruses have been mainly limited to ...

Bao D, Xue R, Zhang M, Lu C, Ma T, Ren C, Zhang T,. N-linked glycosylation plays an important role in budding of NA protein and virulence of influenza viruses. J Virol. 2020 Nov 11:JVI.02042-20.  Abstract  
submitted by kickingbird at Nov, 13, 2020 from J Virol. 2020 Nov 11:JVI.02042-20 (via https://jvi.asm.org/content/early/2020/11/06/JVI.02042-20)
Neuraminidase (NA) has multiple functions in the life cycle of influenza virus, especially in the late stage of virus replication. Both of Hemagglutinin (HA) and NA are highly glycosylated proteins. N-linked ...

Speake HA, Pereira G, Regan AK. Risk of adverse maternal and foetal outcomes associated with inactivated influenza vaccination in first trimester of pregnancy. Paediatr Perinat Epidemiol. 2020 Nov 5.  Abstract  
submitted by kickingbird at Nov, 9, 2020 from Paediatr Perinat Epidemiol. 2020 Nov 5 (via https://onlinelibrary.wiley.com/doi/10.1111/ppe.12715)
Background: In many countries, influenza vaccination is routinely recommended during any stage of pregnancy, yet uptake remains low, particularly in the first trimester. This is thought to be due to maternal ...

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