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2024-7-18 1:16:49
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Cui Y, Li Y, Li M, et al. Evolution and extensive reassortment of H5 influenza viruses isolated from wild birds in China over the past decade. Emerg Microbes Infect. 2020;1-0.  Abstract  
submitted by kickingbird at Jul, 21, 2020 from Emerg Microbes Infect. 2020;1-0 (via https://pubmed.ncbi.nlm.nih.gov/32686602/)
Lethal infection of wild birds with different subtypes of H5 viruses continuously occur. To investigate the genetic evolution and pathogenicity of H5 viruses in wild birds, we performed a detailed genetic ...

Yang CR, King CC, Liu LD, Ku CC. FluConvert and IniFlu: a suite of integrated software to identify novel signatures of emerging influenza viruses with increasing risk. BMC Bioinformatics. 2020;21(1):316.  Abstract  
submitted by kickingbird at Jul, 20, 2020 from BMC Bioinformatics. 2020;21(1):316 (via https://pubmed.ncbi.nlm.nih.gov/32682392/)
Background: The pandemic threat of influenza has attracted great attention worldwide. To assist public health decision-makers, new suites of tools are needed to rapidly process and combine viral information ...

Barberis A, Boudaoud A, Gorrill A, et al. Full-length genome sequences of the first H9N2 avian influenza viruses isolated in the Northeast of Algeria. Virol J. 2020;17(1):108.  Abstract  
submitted by kickingbird at Jul, 20, 2020 from Virol J. 2020;17(1):108 (via https://pubmed.ncbi.nlm.nih.gov/32680533/)
Background: H9N2 avian influenza viruses (AIV) has a worldwide geographic distribution and affects poultry of different types of production. H9N2 AIV was first reported in the Northeast of Algeria in April ...

Zell R, Groth M, Krumhbolz A, Lange J, Philipps A,. Cocirculation of Swine H1N1 Influenza A Virus Lineages in Germany. Viruses. 2020;12(7):E762.  Abstract  
submitted by kickingbird at Jul, 19, 2020 from Viruses. 2020;12(7):E762 (via https://pubmed.ncbi.nlm.nih.gov/32679903/)
The genome analysis of 328 H1N1 swine influenza virus isolates collected in a 13-year long-term swine influenza surveillance in Germany is reported. Viral genomes were sequenced with the Illumina next-generation ...

Liao HY, Wang SC, Ko YA, et al. Chimeric hemagglutinin vaccine elicits broadly protective CD4 and CD8 T cell responses against multiple influenza strains and subtypes. Proc Natl Acad Sci U S A. 2020;202004783.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Proc Natl Acad Sci U S A. 2020;202004783 (via https://pubmed.ncbi.nlm.nih.gov/32669430/)
Vaccination has been used to control the spread of seasonal flu; however, the virus continues to evolve and escape from host immune response through mutation and increasing glycosylation. Efforts have ...

Wei J, Li Z, Yang Y, Ma G, Su Z, Zhang S. An apoferritin-haemagglutinin conjugate vaccine with encapsulated nucleoprotein antigen peptide from influenza virus confers enhanced cross protection. Bioconjug Chem. 2020;10.1021/acs.bioconjchem.0c00.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Bioconjug Chem. 2020;10.1021/acs.bioconjchem.0c00 (via https://pubmed.ncbi.nlm.nih.gov/32678574/)
Naturally occurring self-assembling ferritin nanoparticles have become widely appreciated for vaccine design. In this study, an apoferritin (AFt) nanocage was used as a carrier to construct a biomimetic ...

Ge Z, Gu M, Cai T, et al. Phylogenetic tracing and biological characterization of a novel clade 2.3.2.1 reassortant of H5N6 subtype avian influenza virus in China. Transbound Emerg Dis. 2020;10.1111/tbed.13736.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Transbound Emerg Dis. 2020;10.1111/tbed.13736 (via https://pubmed.ncbi.nlm.nih.gov/32677729/)
In recent years in China, clade 2.3.4.4 H5N6 plus clade 2.3.2.1 H5N1 subtype highly pathogenic avian influenza (HPAI) viruses have gradually become endemic in poultry, and their co-circulation could inevitably ...

Sha TW, Weber M, Kasumba DM, et al. Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner. Virol J. 2020;17(1):107.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Virol J. 2020;17(1):107 (via https://pubmed.ncbi.nlm.nih.gov/32677963/)
Background: The non-structural protein 1 (NS1) of influenza A virus (IAV) is a key player in inhibiting antiviral response in host cells, thereby facilitating its replication. However, other roles of NS1, ...

Paillot R, Regourd E, Behr-Gross ME. Establishment of a candidate equine influenza Florida Clade 2 strain A/eq/Richmond/1/07 horse antiserum as Ph. Eur. Biological Reference Preparation/OIE International Reference Reagent. Bio Sci Notes. 2020;2020:125-140.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Bio Sci Notes. 2020;2020:125-140 (via https://pubmed.ncbi.nlm.nih.gov/32677612/)
Equine influenza (EI) is an important respiratory disease of horses, with welfare and economic consequences. Vaccination remains one of the most efficient prevention methods available. Equine influenza ...

Sultankulova K, Orynbayev M, Kozhabergenov N, et a. Complete Coding Genome Sequence of an Avian Influenza A/H3N8 Virus Strain Detected in North Kazakhstan in 2018. Microbiol Resour Announc. 2020;9(29):e00441-20.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Microbiol Resour Announc. 2020;9(29):e00441-20 (via https://pubmed.ncbi.nlm.nih.gov/32675181/)
We report the complete coding genome sequence of the influenza A/H3N8 virus, isolated from Anas querquedula in northern Kazakhstan in 2018. Phylogenetic analysis of the surface antigens of strain A/garganey/North-Kazakhstan/45/2018 ...

Zhou X, Liu Y, Jin Y, et al. Immune responses after influenza vaccination in patients of primary Sj?gren´s syndrome. Rheumatology (Oxford). 2020;keaa243.  Abstract  
submitted by kickingbird at Jul, 18, 2020 from Rheumatology (Oxford). 2020;keaa243 (via https://pubmed.ncbi.nlm.nih.gov/32671409/)
Objectives: Influenza vaccination is effective in preventing infections in most people. This study aimed to assess the changes of immune responses in primary Sj?gren's Syndrome (pSS) patients after influenza ...

Horwood PF, Fabrizio T, Horm SV, et al. Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses. Emerg Microbes Infect. 2020;1-36.  Abstract  
submitted by kickingbird at Jul, 16, 2020 from Emerg Microbes Infect. 2020;1-36 (via https://pubmed.ncbi.nlm.nih.gov/32666894/)
Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has intermittently infected humans. During ...

Tricoche AD, Wagner AL, Balmaseda A, et al. Symptoms, Infection Duration, and Hemagglutinin Inhibition Antibody Response in Influenza A Infections. J Infect Dis. 2020;jiaa426.  Abstract  
submitted by kickingbird at Jul, 16, 2020 from J Infect Dis. 2020;jiaa426 (via https://pubmed.ncbi.nlm.nih.gov/32668454/)
Many influenza studies assume that symptomatic and asymptomatic cases have equivalent antibody responses. This study examines the relationship between influenza symptoms and serological response. Influenza-positive ...

Yang G, Wang X, Yang Y, Yang R, Gowetski DB, Paula. Quantitation of residual valproic acid in flu vaccine drug substance. J Chromatogr B Analyt Technol Biomed Life Sci. 202.  Abstract  
submitted by kickingbird at Jul, 16, 2020 from J Chromatogr B Analyt Technol Biomed Life Sci. 202 (via https://pubmed.ncbi.nlm.nih.gov/32668376/)
Quantitative measurement of process-related impurities is a critical safety requirement for the production of drug substances of vaccine and therapeutic biologics. A simple and sensitive HPLC method has ...

Li YT, Chen CC, Chang AM, Chao DY, Smith GJD. Co-circulation of both low and highly pathogenic avian influenza H5 viruses in current poultry epidemics in Taiwan. Virus Evol. 2020;6(1):veaa037.  Abstract  
submitted by kickingbird at Jul, 15, 2020 from Virus Evol. 2020;6(1):veaa037 (via https://pubmed.ncbi.nlm.nih.gov/32661493/)
Highly pathogenic avian influenza (HPAI) A(H5) viruses belonging to clade 2.3.4.4c of the A/goose/Guangdong/1/96-like (Gs/GD) lineage caused severe global outbreaks in domestic birds from 2014 to 2015, ...

Ellebedy AH, Nachbagauer R, Jackson KJL, et al. Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans. Proc Natl Acad Sci U S A. 2020;201906613.  Abstract  
submitted by kickingbird at Jul, 15, 2020 from Proc Natl Acad Sci U S A. 2020;201906613 (via https://pubmed.ncbi.nlm.nih.gov/32661157/)
There is a need for improved influenza vaccines. In this study we compared the antibody responses in humans after vaccination with an AS03-adjuvanted versus nonadjuvanted H5N1 avian influenza virus inactivated ...

Wang M, Huang Y, Gu W, Wang H. Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice. J Vis Exp. 2020;(160):10.3791/60523.  Abstract  
submitted by kickingbird at Jul, 15, 2020 from J Vis Exp. 2020;(160):10.3791/60523 (via https://pubmed.ncbi.nlm.nih.gov/32658200/)
T Follicular Helper (Tfh) cells are an independent CD4+ T cell subset specialized in providing help for germinal center (GC) development and generation of high-affinity antibodies. In influenza virus infection, ...

Nguyen-Van-Tam JS, Killingley B, Enstone J, et al. Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environment. PLoS Pathog. 2020;16(7):e1008704.  Abstract  
submitted by kickingbird at Jul, 14, 2020 from PLoS Pathog. 2020;16(7):e1008704 (via https://pubmed.ncbi.nlm.nih.gov/32658939/)
Uncertainty about the importance of influenza transmission by airborne droplet nuclei generates controversy for infection control. Human challenge-transmission studies have been supported as the most promising ...

Yang F, Xiao Y, Liu F, Yao H, Wu N, Wu H. Development of a Monoclonal Antibody-Based Antigen Capture Enzyme-Linked Immunosorbent Assay for Detection of H7N9 Subtype Avian Influenza Virus. J Med Virol. 2020;10.1002/jmv.26292.  Abstract  
submitted by kickingbird at Jul, 12, 2020 from J Med Virol. 2020;10.1002/jmv.26292 (via https://pubmed.ncbi.nlm.nih.gov/32648948/)
In order to establish a rapid detection method for H7N9 avian influenza virus (AIV), monoclonal antibodies (mAbs) against hemagglutinin (HA) of H7N9 were developed to establish an antigen capture enzyme-linked ...

Guk K, Kim H, Lee M, et al.. Development of A4 Antibody for Detection of Neuraminidase I223R/H275Y-associated Antiviral Multidrug-Resistant Influenza Virus. Nat Commun. 2020;11(1):3418. Published 2020 Jul 9..  Abstract  
submitted by kickingbird at Jul, 12, 2020 from Nat Commun. 2020;11(1):3418. Published 2020 Jul 9. (via https://pubmed.ncbi.nlm.nih.gov/32647286/)
The emergence and spread of antiviral drug-resistant viruses have been a worldwide challenge and a great concern for patient care. We report A4 antibody specifically recognizing and binding to the mutant ...

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