Bolton JS, Klim H, Wellens J, Edmans M, Obolski U,. An Antigenic Thrift-Based Approach to Influenza Vaccine Design. Vaccines (Basel). 2021 Jun 16;9(6):657. Abstract
submitted by kickingbird at Jul, 4, 2021 from Vaccines (Basel). 2021 Jun 16;9(6):657 (via https://www.mdpi.com/2076-393X/9/6/657)
The antigenic drift theory states that influenza evolves via the gradual accumulation of mutations, decreasing a host's immune protection against previous strains. Influenza vaccines are designed accordingly, ... Wiggins KB, Smith MA, Schultz-Cherry S. The Nature of Immune Responses to Influenza Vaccination in High-Risk Populations. Viruses. 2021 Jun 9;13(6):1109. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 9;13(6):1109 (via https://www.mdpi.com/1999-4915/13/6/1109)
The current pandemic has brought a renewed appreciation for the critical importance of vaccines for the promotion of both individual and public health. Influenza vaccines have been our primary tool for ... Chrzastek K, Segovia K, Torchetti M, Killian ML, P. Virus Adaptation Following Experimental Infection of Chickens with a Domestic Duck Low Pathogenic Avian Influenza Isolate from the 2017 USA H7N9 Outbreak Identifies Polymorphic Mutations in Multiple G. Viruses. 2021 Jun 18;13(6):1166. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 18;13(6):1166 (via https://www.mdpi.com/1999-4915/13/6/1166)
In March 2017, highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) subtype H7N9 were detected from poultry farms and backyard birds in several states in the southeast United States. ... Soh YQS, Malone KD, Eguia RT, Bloom JD. Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir. Viruses. 2021 Jun 22;13(7):1196. Abstract
submitted by kickingbird at Jul, 4, 2021 from Viruses. 2021 Jun 22;13(7):1196 (via https://www.mdpi.com/1999-4915/13/7/1196)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying ... Xiao Y, Zhang W, Pan M, Bauer DLV, Bi Y, Cao M, Fo. A synergistic effect between 3´ terminal noncoding and adjacent coding regions of influenza A virus HA segment on template preference. J Virol. 2021 Jun 30:JVI0087821. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0087821 (via https://journals.asm.org/doi/10.1128/JVI.00878-21)
The influenza A virus genome is comprised of eight single-stranded negative-sense viral RNA (vRNA) segments. Each of the eight vRNA segments contains segment-specific nonconserved noncoding regions (NCRs) ... Yu J, Huang C, Sheng Z, Wang Z, Li F, Wang D. Identification of One Critical Amino Acid Residue of the Nucleoprotein as a Determinant for in vitro Viral Replication Fitness of Influenza D Virus. J Virol. 2021 Jun 30:JVI0097121. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Virol. 2021 Jun 30:JVI0097121 (via https://journals.asm.org/doi/10.1128/JVI.00971-21)
The newly identified influenza D virus (IDV) of the Orthomyxoviridae family has a wide host range with broad geographical distribution. Despite the first appearance in U.S. pig herds in 2011, subsequent ... Wang Y, Niu S, Zhang B, Yang C, Zhou Z. The whole genome analysis for the first human infection with H10N3 influenza virus in China. J Infect. 2021 Jun 27:S0163-4453(21)00318-2. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect. 2021 Jun 27:S0163-4453(21)00318-2 (via https://www.journalofinfection.com/article/S0163-4453(21)003)
A strain of H10N3 influenza virus, A/Jiangsu/428/2021/H10N3, was isolated from patient in Jiangsu province, eastern China. Phylogenetic analysis illustrated this human H10N3 virus was a low pathogenic ... Cui J, Cui P, Shi J, Fan W, Xing X, Gu W, Zhang Y,. Continued evolution of H6 avian influenza viruses isolated from farms in China between 2014 and 2018. Transbound Emerg Dis. 2021 Jun 30. Abstract
submitted by kickingbird at Jul, 2, 2021 from Transbound Emerg Dis. 2021 Jun 30 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14212)
H6 avian influenza virus (AIV) is one of the most prevalent AIV subtypes in the world. Our previous studies have demonstrated that H6 AIVs isolated from live poultry markets pose a potential threat to ... Guo F, Roy A, Wang R, Yang J, Zhang Z, Luo W, Shen. Host Adaptive Evolution of Avian-Origin H3N2 Canine Influenza Virus. Front Microbiol. 2021 Jun 14;12:655228. Abstract
submitted by kickingbird at Jul, 2, 2021 from Front Microbiol. 2021 Jun 14;12:655228 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6552)
Since its first isolation in around 2007, the avian-origin H3N2 canine influenza virus (CIV) has become established and continues to circulate in dog populations. This virus serves as a useful model for ... Knight ML, Fan H, Bauer DLV, Grimes JM, Fodor E, K. Structure of an H3N2 influenza virus nucleoprotein. Acta Crystallogr F Struct Biol Commun. 2021 Jul 1;. Abstract
submitted by kickingbird at Jul, 2, 2021 from Acta Crystallogr F Struct Biol Commun. 2021 Jul 1; (via https://scripts.iucr.org/cgi-bin/paper?S2053230X2100635X)
Influenza A viruses of the H1N1 and H3N2 subtypes are responsible for seasonal epidemic events. The influenza nucleoprotein (NP) binds to the viral genomic RNA and is essential for its replication. Efforts ... Santos NB, Vaz da Silva ZE, Gomes C, Reis CA, Amor. Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology. PLoS Pathog. 2021 Jul 1;17(7):e1009381. Abstract
submitted by kickingbird at Jul, 2, 2021 from PLoS Pathog. 2021 Jul 1;17(7):e1009381 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Clearance of viral infections, such as SARS-CoV-2 and influenza A virus (IAV), must be fine-tuned to eliminate the pathogen without causing immunopathology. As such, an aggressive initial innate immune ... Giacomelli Cao R, Christian L, Xu Z, Jaramillo L,. Early changes in interferon gene expression and antibody responses following influenza vaccination in pregnant women. J Infect Dis. 2021 Jul 1:jiab345. Abstract
submitted by kickingbird at Jul, 2, 2021 from J Infect Dis. 2021 Jul 1:jiab345 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Influenza immunization during pregnancy provides protection to the mother and the infant. Studies in adults and children with inactivated influenza vaccine (IIV) have identified changes in ... Wang Y, Li S, Dong C, Ma Y, Song Y, Zhu W, Kim J,. Skin vaccination with dissolvable microneedle patches incorporating influenza neuraminidase and flagellin protein nanoparticles induces broad immune protection against multiple influenza viruses. ACS Appl Bio Mater. 2021 Jun 21;4(6):4953-4961. Abstract
submitted by kickingbird at Jun, 29, 2021 from ACS Appl Bio Mater. 2021 Jun 21;4(6):4953-4961 (via https://pubs.acs.org/doi/10.1021/acsabm.1c00240)
We generated self-adjuvanted protein nanoparticles of conserved influenza antigens and immunized mice via skin vaccination with dissolvable microneedle patches (MNPs) to increase the strength and breadth ... Zhang Q, Mei X, Zhang C, Li J, Chang N, Aji D, Shi. Novel reassortant 2.3.4.4B H5N6 highly pathogenic avian influenza viruses circulating among wild, domestic birds in Xinjiang, Northwest China. J Vet Sci. 2021 May 11. Abstract
submitted by kickingbird at Jun, 26, 2021 from J Vet Sci. 2021 May 11 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.2021.22.e43)
Background: The H5 avian influenza viruses (AIVs) of clade 2.3.4.4 circulate in wild and domestic birds worldwide. In 2017, nine strains of H5N6 AIVs were isolated from aquatic poultry in Xinjiang, Northwest ... Blaurock C, Breithaupt A, Scheibner D, Bagato O, K. Preferential selection and contribution of non-structural protein 1 (NS1) to the efficient transmission of the panzootic avian influenza H5N8 2.3.4.4 clades A and B viruses in chickens and ducks. J Virol. 2021 Jun 23:JVI0044521. Abstract
submitted by kickingbird at Jun, 26, 2021 from J Virol. 2021 Jun 23:JVI0044521 (via https://journals.asm.org/doi/10.1128/JVI.00445-21)
Highly pathogenic avian influenza viruses H5N8 clade 2.3.4.4 caused outbreaks in poultry at an unprecedented global scale. The virus was spread by wild birds in Asia in two waves: clade-2.3.4.4A in 2014/2015 ... Du L, Pang Y. A novel data-driven methodology for influenza outbreak detection and prediction. Sci Rep. 2021 Jun 24;11(1):13275. Abstract
submitted by kickingbird at Jun, 26, 2021 from Sci Rep. 2021 Jun 24;11(1):13275 (via https://www.nature.com/articles/s41598-021-92484-6)
Influenza is an infectious disease that leads to an estimated 5 million cases of severe illness and 650,000 respiratory deaths worldwide each year. The early detection and prediction of influenza outbreaks ... Vergne T, Gubbins S, Guinat C, Bauzile B, Delpont. Inferring within-flock transmission dynamics of highly pathogenic avian influenza H5N8 virus in France, 2020. Transbound Emerg Dis. 2021 Jun 25. Abstract
submitted by kickingbird at Jun, 26, 2021 from Transbound Emerg Dis. 2021 Jun 25 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14202)
Following the emergence of highly pathogenic avian influenza (H5N8) in France in early December 2020, we used duck mortality data from the index farm to investigate within-flock transmission dynamics. ... Skarlupka AL, Bebin-Blackwell AG, Sumner SF, Ross. Universal influenza virus neuraminidase vaccine elicits protective immune responses against human seasonal and pre-pandemic strains. J Virol. 2021 Jun 23:JVI0075921. Abstract
submitted by kickingbird at Jun, 25, 2021 from J Virol. 2021 Jun 23:JVI0075921 (via https://journals.asm.org/doi/10.1128/JVI.00759-21)
The hemagglutinin (HA) surface protein is the primary immune target for most influenza vaccines. The neuraminidase (NA) surface protein is often a secondary target for vaccine designs. In this study, computationally ... Zhang C, Guo K, Cui H, Chen L, Zhang C, Wang X, Li. Risk of Environmental Exposure to H7N9 Influenza Virus via Airborne and Surface Routes in a Live Poultry Market in Hebei, China. Front Cell Infect Microbiol. 2021 Jun 7;11:688007. Abstract
submitted by kickingbird at Jun, 25, 2021 from Front Cell Infect Microbiol. 2021 Jun 7;11:688007 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.6880)
Environmental transmission of viruses to humans has become an early warning for potential epidemic outbreaks, such as SARS-CoV-2 and influenza virus outbreaks. Recently, an H7N9 virus, A/environment/Hebei/621/2019 ... Xiao Y, Yang F, Liu F, Cheng L, Yao H, Wu N, Wu H. Development of an antigen-ELISA and a colloidal gold-based immunochromatographic strip based on monoclonal antibodies for detection of avian influenza A(H5) viruses. J Vet Diagn Invest. 2021 Jun 24:10406387211027538. Abstract
submitted by kickingbird at Jun, 25, 2021 from J Vet Diagn Invest. 2021 Jun 24:10406387211027538 (via https://journals.sagepub.com/doi/10.1177/10406387211027538)
vian influenza A(H5) viruses (avian IAVs) pose a major threat to the economy and public health. We developed an antigen-ELISA (ag-ELISA) and a colloidal gold-based immunochromatographic strip for the rapid ... 8183 items, 20/Page, Page[116/410][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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