Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA,. Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in human and murine airway cells. J Virol. 2021 Jul 28:JVI0090621. Abstract
submitted by kickingbird at Jul, 29, 2021 from J Virol. 2021 Jul 28:JVI0090621 (via https://journals.asm.org/doi/10.1128/JVI.00906-21)
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs possess a monobasic HA cleavage site cleaved by trypsin-like proteases. Previously, ... Ryt-Hansen P, Krog JS, Breum S?, Hjulsager CK, Ped. Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses. Elife. 2021 Jul 27;10:e60940. Abstract
submitted by kickingbird at Jul, 29, 2021 from Elife. 2021 Jul 27;10:e60940 (via https://elifesciences.org/articles/60940)
Since the influenza pandemic in 2009, there has been an increased focus on swine influenza A virus (swIAV) surveillance. This paper describes the results of the surveillance of swIAV in Danish swine from ... Lean FZX, Nú?ez A, Banyard AC, Reid SM, Brown IH,. Gross pathology associated with highly pathogenic avian influenza H5N8 and H5N1 in naturally infected birds in the UK (2020-2021). Vet Rec. 2021 Jul 26:e731. Abstract
submitted by kickingbird at Jul, 28, 2021 from Vet Rec. 2021 Jul 26:e731 (via https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vetr)
Background: Multiple outbreaks with highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b viruses, including H5N8 and H5N1, have occurred in the United Kingdom, as well as in other European countries, ... Plant EP, Ye Z. A Codon-Pair Bias Associated With Network Interactions in Influenza A, B, and C Genomes. Front Genet. 2021 Jul 6;12:699141.. Abstract
submitted by kickingbird at Jul, 24, 2021 from Front Genet. 2021 Jul 6;12:699141. (via https://www.frontiersin.org/articles/10.3389/fgene.2021.6991)
A new codon-pair bias present in the genomes of different types of influenza virus is described. Codons with fewer network interactions are more frequency paired together than other codon-pairs in influenza ... Kye SJ, Park MJ, Kim NY, Lee YN, Heo GB, Baek YK,. Pathogenicity of H9N2 low pathogenic avian influenza viruses of different lineages isolated from live bird markets tested in three animal models: SPF chickens, Korean native chickens, and ducks. Poult Sci. 2021 Jun 9;100(9):101318. Abstract
submitted by kickingbird at Jul, 23, 2021 from Poult Sci. 2021 Jun 9;100(9):101318 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Since its first appearance in 1996, H9N2 avian influenza virus (AIV) of the Y439 lineage persisted in Korean live bird markets (LBMs) until the last documented occurrence in 2018. However, in June 2020, ... Piantham C, Ito K.. Modeling the selective advantage of new amino acids on the hemagglutinin of H1N1 influenza viruses using their patient age distributions. Virus Evol. 2021 May 28;7(1):veab049. Abstract
submitted by kickingbird at Jul, 23, 2021 from Virus Evol. 2021 May 28;7(1):veab049 (via https://academic.oup.com/ve/article/7/1/veab049/6287670)
In 2009, a new strain of H1N1 influenza A virus caused a pandemic, and its descendant strains are causing seasonal epidemics worldwide. Given the high mutation rate of influenza viruses, variant strains ... Yang J, Zhang P, Huang M, Qiao S, Liu Q, Chen H, T. Key amino acids of M1-41 and M2-27 determine growth and pathogenicity of chimeric H17 bat influenza virus in cells and in mice. J Virol. 2021 Jul 21:JVI0101921. Abstract
submitted by kickingbird at Jul, 23, 2021 from J Virol. 2021 Jul 21:JVI0101921 (via https://journals.asm.org/doi/10.1128/JVI.01019-21)
Based on our previous studies, we show that M gene is critical for viral replication and pathogenicity of the chimeric H17 bat influenza virus (Bat09:mH1mN1) by replacing bat M gene with those from human ... Sobolev I, Sharshov K, Dubovitskiy N, Kurskaya O,. Highly Pathogenic Avian Influenza A(H5N8) Virus Clade 2.3.4.4b, Western Siberia, Russia, 2020. Emerg Infect Dis. 2021 Aug;27(8):2224-2227. Abstract
submitted by kickingbird at Jul, 23, 2021 from Emerg Infect Dis. 2021 Aug;27(8):2224-2227 (via https://pubmed.ncbi.nlm.nih.gov/34287138/)
Two variants of highly pathogenic avian influenza A(H5N8) virus were detected in dead poultry in Western Siberia, Russia, during August and September 2020. One variant was represented by viruses of clade ... Norrulashikin MA, Yusof F, Hanafiah NHM, Norrulash. Modelling monthly influenza cases in Malaysia. PLoS One. 2021 Jul 21;16(7):e0254137. Abstract
submitted by kickingbird at Jul, 23, 2021 from PLoS One. 2021 Jul 21;16(7):e0254137 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
The increasing trend in the number new cases of influenza every year as reported by WHO is concerning, especially in Malaysia. To date, there is no local research under healthcare sector that implements ... Vu TH, Hong Y, Truong AD, Lee J, Lee S, Song KD, C. Cytokine-cytokine receptor interactions in the highly pathogenic avian influenza H5N1 virus-infected lungs of genetically disparate Ri chicken lines. Anim Biosci. 2021 Jun 24. Abstract
submitted by kickingbird at Jul, 23, 2021 from Anim Biosci. 2021 Jun 24 (via https://www.animbiosci.org/journal/view.php?doi=10.5713/ab.2)
Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry as well as the economy and remains a potential source of pandemic infection in humans. Antiviral genes ... Sood R, Kumar N, Gokhe SS, Pateriya AK, Bhat S, Bh. Identification and molecular characterization of H9N2 viruses carrying multiple mammalian adaptation markers in resident birds in central-western wetlands in India. Infect Genet Evol. 2021 Jul 19:105005. Abstract
submitted by kickingbird at Jul, 23, 2021 from Infect Genet Evol. 2021 Jul 19:105005 (via https://www.sciencedirect.com/science/article/abs/pii/S15671)
We report here a targeted risk-based study to investigate the presence of influenza A viruses at the migratory-wild-domestic bird interface across the major wetlands of central India's Maharashtra state ... Shiimori M, Nukiwa R, Imai Y. Dynamics of the host chromatin 3-dimensional response to influenza virus infection. Int Immunol. 2021 Jul 19:dxab043. Abstract
submitted by kickingbird at Jul, 21, 2021 from Int Immunol. 2021 Jul 19:dxab043 (via https://academic.oup.com/intimm/advance-article/doi/10.1093/)
The spatial organization of chromatin is known to be highly dynamic in response to environmental stress. However, it remains unknown how chromatin dynamics contributes to or modulates the pathogenesis ... Qu Z, Meng F, Shi J, Deng G, Zeng X, Ge J, Li Y, L. A Novel Intronic Circular RNA Antagonizes Influenza Virus by Absorbing a microRNA That Degrades CREBBP and Accelerating IFN-β Production. mBio. 2021 Jul 20:e0101721. Abstract
submitted by kickingbird at Jul, 21, 2021 from mBio. 2021 Jul 20:e0101721 (via https://journals.asm.org/doi/10.1128/mBio.01017-21)
Virus-host interactions are complicated processes, and multiple cellular proteins promote or inhibit viral replication through different mechanisms. Recent progress has implicated circular RNAs (circRNAs) ... Zhao MZ, Guo X, Sun B, Sun XF, Pang GF, Yang LY, Z. HA of H1N1 enhanced the expression of ICAM-1 and IL-6 in HUVECs and pathological injury in the lungs in mice. Gene. 2021 Jul 15:145854. Abstract
submitted by kickingbird at Jul, 20, 2021 from Gene. 2021 Jul 15:145854 (via https://www.sciencedirect.com/science/article/pii/S037811192)
Both COVID-19 and influenza are viral respiratory tract infections and the epidemics of viral respiratory tract infections remain highly prevalent with lethal consequences in susceptible individuals. Expression ... Leung VKY, Deng YM, Todd A, Peck H, Buettner I, Za. A second external quality assessment of isolation and identification of influenza viruses in cell culture in the Asia Pacific region highlights improved performance by participating laboratories. J Clin Virol. 2021 Jul 7;142:104907. Abstract
submitted by kickingbird at Jul, 20, 2021 from J Clin Virol. 2021 Jul 7;142:104907 (via https://www.sciencedirect.com/science/article/abs/pii/S13866)
Influenza viruses must be amplified in cell culture for detailed antigenic analysis and for phenotypic assays assessing susceptibility to antiviral drugs or for other assays. Following on from the first ... Griggs EP, Flannery B, Foppa IM, Gaglani M, Murthy. Role of Age in Spread of Influenza, 2011-2019, U.S. Influenza Vaccine Effectiveness Network. Am J Epidemiol. 2021 Jul 16:kwab205. Abstract
submitted by kickingbird at Jul, 20, 2021 from Am J Epidemiol. 2021 Jul 16:kwab205 (via https://academic.oup.com/aje/advance-article/doi/10.1093/aje)
Intra-season timing of influenza infection among persons of different ages could reflect relative contributions to propagation of seasonal epidemics and has not been examined among ambulatory patients. ... Wen S, Wei H, Liao Q, Li M, Zhong S, Cheng Y, Huan. Identification of Two Novel Candidate Genetic Variants Associated With the Responsiveness to Influenza Vaccination. Front Immunol. 2021 Jul 1;12:664024. Abstract
submitted by kickingbird at Jul, 20, 2021 from Front Immunol. 2021 Jul 1;12:664024 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6640)
Background: Annual vaccination is the most effective prevention of influenza infection. Up to now, a series of studies have demonstrated the role of genetic variants in regulating the antibody response ... Mo J, Youk S, Pantin-Jackwood MJ, Suarez DL, Lee D. The pathogenicity and transmission of live bird market H2N2 avian influenza viruses in chickens, Pekin ducks, and guinea fowl. Vet Microbiol. 2021 Jul 7;260:109180.. Abstract
submitted by kickingbird at Jul, 19, 2021 from Vet Microbiol. 2021 Jul 7;260:109180. (via https://www.sciencedirect.com/science/article/pii/S037811352)
H2N2 subtype low pathogenic avian influenza viruses (LPAIVs) have persisted in live bird markets (LBMs) in the Northeastern United States since 2014. Although unrelated to the 1957 pandemic H2N2 lineage, ... Van den Hoecke S, Ballegeer M, Vrancken B, Deng L,. In Vivo Therapy with M2e-Specific IgG Selects for an Influenza A Virus Mutant with Delayed Matrix Protein 2 Expression. mBio. 2021 Jul 13:e0074521. Abstract
submitted by kickingbird at Jul, 16, 2021 from mBio. 2021 Jul 13:e0074521 (via https://journals.asm.org/doi/10.1128/mBio.00745-21)
The ectodomain of matrix protein 2 (M2e) of influenza A viruses is a universal influenza A vaccine candidate. Here, we report potential evasion strategies of influenza A viruses under in vivo passive anti-M2e ... Vieira MC, Donato CM, Arevalo P, Rimmelzwaan GF, W. Lineage-specific protection and immune imprinting shape the age distributions of influenza B cases. Nat Commun. 2021 Jul 14;12(1):4313. Abstract
submitted by kickingbird at Jul, 16, 2021 from Nat Commun. 2021 Jul 14;12(1):4313 (via https://www.nature.com/articles/s41467-021-24566-y)
How a history of influenza virus infections contributes to protection is not fully understood, but such protection might explain the contrasting age distributions of cases of the two lineages of influenza ... 8183 items, 20/Page, Page[114/410][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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