Frymus T, Belák S, Egberink H, Hofmann-Lehmann R,. Influenza Virus Infections in Cats. Viruses. 2021 Jul 23;13(8):1435. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Jul 23;13(8):1435 (via https://www.mdpi.com/1999-4915/13/8/1435)
In the past, cats were considered resistant to influenza. Today, we know that they are susceptible to some influenza A viruses (IAVs) originating in other species. Usually, the outcome is only subclinical ... Stadtmueller MN, Bhatia S, Kiran P, Hilsch M, Reit. Evaluation of Multivalent Sialylated Polyglycerols for Resistance Induction in and Broad Antiviral Activity against Influenza A Viruses. J Med Chem. 2021 Aug 25. Abstract
submitted by kickingbird at Aug, 26, 2021 from J Med Chem. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00794)
The development of multivalent sialic acid-based inhibitors active against a variety of influenza A virus (IAV) strains has been hampered by high genetic and structural variability of the targeted viral ... Wilks LR, Joshi G, Grisham MR, Gill HS. Tyrosine-Based Cross-Linking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A. ACS Infect Dis. 2021 Aug 25. Abstract
submitted by kickingbird at Aug, 26, 2021 from ACS Infect Dis. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00219)
A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine cross-linking reaction. A reactive tag comprising histidine and tyrosine ... Machado MAA, Moura CS, Abrahamowicz M, Ward BJ, Pi. Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons. NPJ Vaccines. 2021 Aug 24;6(1):108. Abstract
submitted by kickingbird at Aug, 26, 2021 from NPJ Vaccines. 2021 Aug 24;6(1):108 (via https://www.nature.com/articles/s41541-021-00373-w)
Influenza immunization protects seniors against influenza and its potentially serious complications. It is uncertain whether standard-dose (SD) quadrivalent vaccine offers better protection over other ... Zhang J, Huang L, Chen Y, Wang X, Liao M, Qi W. Avian influenza H10 subtype viruses continuously pose threat to public health in China. J Infect. 2021 Aug 8:S0163-4453(21)00386-8. Abstract
submitted by kickingbird at Aug, 25, 2021 from J Infect. 2021 Aug 8:S0163-4453(21)00386-8 (via J Infect. 2021 Aug 8:S0163-4453(21)00386-8)
Wang and colleges recently reported in this journal the first case of human infection with H10N3 virus in China. 1 In China, H10 subtype (H10N2, H10N3, H10N6, H10N7, H10N8, and et. al.) avian influenza ... Zhang J, Ma K, Li B, Chen Y, Qiu Z, Xing J, Huang. A risk marker of tribasic hemagglutinin cleavage site in influenza A (H9N2) virus. Commun Biol. 2021 Jan 15;4(1):71. Abstract
submitted by kickingbird at Aug, 25, 2021 from Commun Biol. 2021 Jan 15;4(1):71 (via https://www.nature.com/articles/s42003-020-01589-7)
Low pathogenic avian influenza A(H9N2) virus is endemic worldwide and continually recruit internal genes to generate human-infecting H5N1, H5N6, H7N9, and H10N8 influenza variants. Here we show that hemagglutinin ... Li X, Gu M, Wang X, Gao R, Bu X, Hao X, Ma J, Hu J. G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment. BMC Vet Res. 2021 Feb 15;17(1):80. Abstract
submitted by kickingbird at Aug, 25, 2021 from BMC Vet Res. 2021 Feb 15;17(1):80 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such ... Turner JCM, Barman S, Feeroz MM, Hasan MK, Akhtar. Highly Pathogenic Avian Influenza A(H5N6) Virus Clade 2.3.4.4h in Wild Birds and Live Poultry Markets, Bangladesh. Emerg Infect Dis. 2021 Sep;27(9):2492-2494.. Abstract
submitted by kickingbird at Aug, 24, 2021 from Emerg Infect Dis. 2021 Sep;27(9):2492-2494. (via https://wwwnc.cdc.gov/eid/article/27/9/21-0819_article)
Migratory birds play a major role in spreading influenza viruses over long distances. We report highly pathogenic avian influenza A(H5N6) viruses in migratory and resident ducks in Bangladesh. The viruses ... Pascua PNQ, Jones JC, Marathe BM, Seiler P, Caufie. Baloxavir treatment delays influenza B virus transmission in ferrets and results in limited generation of drug-resistant variants. Antimicrob Agents Chemother. 2021 Aug 23:AAC011372. Abstract
submitted by kickingbird at Aug, 24, 2021 from Antimicrob Agents Chemother. 2021 Aug 23:AAC011372 (via https://journals.asm.org/doi/10.1128/AAC.01137-21)
Clinical efficacy of the influenza antiviral baloxavir marboxil (baloxavir) is compromised by treatment-emergent variants harboring a polymerase acidic protein I38T substitution. However, the fitness of ... Chakma S, Osmani MG, Akwar H, Hasan Z, Nasrin T, K. Risk Areas for Influenza A(H5) Environmental Contamination in Live Bird Markets, Dhaka, Bangladesh. Emerg Infect Dis. 2021 Sep;27(9):2399-2408. Abstract
submitted by kickingbird at Aug, 24, 2021 from Emerg Infect Dis. 2021 Sep;27(9):2399-2408 (via https://wwwnc.cdc.gov/eid/article/27/9/20-4447_article)
We evaluated the presence of influenza A(H5) virus environmental contamination in live bird markets (LBMs) in Dhaka, Bangladesh. By using Bernoulli generalized linear models and multinomial logistic regression ... Blaurock C, Blohm U, Luttermann C, Holzerland J, S. The C-Terminus of Non-Structural Protein 1 (NS1) in H5N8 Clade 2.3.4.4 Avian Influenza Virus Affects Virus Fitness in Human Cells and Virulence in Mice. Emerg Microbes Infect. 2021 Aug 22:1-48.. Abstract
submitted by kickingbird at Aug, 24, 2021 from Emerg Microbes Infect. 2021 Aug 22:1-48. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) ... Peng HK, Dombkowski KJ, Freed GL, Creary SE, Smith. Influenza immunization coverage of children with sickle cell disease. Vaccine. 2021 Aug 17:S0264-410X(21)01072-0. Abstract
submitted by kickingbird at Aug, 22, 2021 from Vaccine. 2021 Aug 17:S0264-410X(21)01072-0 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Objectives: To assess receipt of annual flu immunization among children living with sickle cell disease (SCD).Methods: Receipt of flu immunization (2014-2019) by SCD status was assessed among all Michigan ... Han T, Lai Y, Jiang Y, Liu X, Li D. Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines. PeerJ. 2021 Aug 3;9:e11892. Abstract
submitted by kickingbird at Aug, 22, 2021 from PeerJ. 2021 Aug 3;9:e11892 (via https://peerj.com/articles/11892/)
Objective: To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.Methods: Human pulmonary ... Flores-Torres AS, Rendon A, Salinas-Carmona MC, Sa. Human Eosinophils Reduce Viral Titer, Secrete IL-8, and Increase RIG-I Expression in Response to Influenza A H1N1 pdm09. Viral Immunol. 2021 Aug 19. Abstract
submitted by kickingbird at Aug, 22, 2021 from Viral Immunol. 2021 Aug 19 (via https://www.liebertpub.com/doi/10.1089/vim.2021.0004)
Eosinophils participate in the immune response against many pathogens, including viruses. Since mouse eosinophils are susceptible to influenza A virus infection and possess antiviral activity, we evaluated ... Gao R, Zheng H, Liu K, Ji Z, Cai M, Gu M, Hu J, Li. Genesis, Evolution and Host Species Distribution of influenza A (H10N3) Virus in China. J Infect. 2021 Aug 17:S0163-4453(21)00403-5. Abstract
submitted by kickingbird at Aug, 22, 2021 from J Infect. 2021 Aug 17:S0163-4453(21)00403-5 (via https://www.journalofinfection.com/article/S0163-4453(21)004)
A recent article by Wang in the Journal of Infection ( 1 ) confirmed the first case of human infection with H10N3 avian influenza virus (AIV) in Zhenjiang, Jiangsu Province, China, in April 2021. Transmission ... Chen Y, Graf L, Chen T, Liao Q, Bai T, Petric PP,. Rare variant MX1 alleles increase human susceptibility to zoonotic H7N9 influenza virus. Science. 2021 Aug 20;373(6557):918-922. Abstract
submitted by kickingbird at Aug, 20, 2021 from Science. 2021 Aug 20;373(6557):918-922 (via https://science.sciencemag.org/content/373/6557/918)
Zoonotic avian influenza A virus (IAV) infections are rare. Sustained transmission of these IAVs between humans has not been observed, suggesting a role for host genes. We used whole-genome sequencing ... Cardona C, Wileman B, Malladi S, Ceballos R, Culha. The Risk of Highly Pathogenic Influenza A Virus Transmission to Turkey Hen Flocks Through Artificial Insemination. Avian Dis. 2021 Jun;65(2):303-309. Abstract
submitted by kickingbird at Aug, 20, 2021 from Avian Dis. 2021 Jun;65(2):303-309 (via https://bioone.org/journals/avian-diseases/volume-65/issue-2)
Artificial insemination is a routine practice for turkeys that can introduce pathogens into breeder flocks in a variety of ways. In this manuscript, a risk analysis on the potential transmission of highly ... Zhong ZJ, Hu XT, Cheng LP, Zhang XY, Zhang Q, Zhan. Discovery of novel thiophene derivatives as potent neuraminidase inhibitors. Eur J Med Chem. 2021 Aug 13;225:113762. Abstract
submitted by kickingbird at Aug, 20, 2021 from Eur J Med Chem. 2021 Aug 13;225:113762 (via https://www.sciencedirect.com/science/article/abs/pii/S02235)
Neuraminidase (NA) is an important target for the treatment of influenza. In this study, a new lead NA inhibitor, 4 (ZINC01121127), was discovered by pharmacophore-based virtual screening and molecular ... Burnham AJ, Miller JR, Singh I, Billings EA, Rush. Novel isoforms of influenza virus PA-X and PB1-F2 indicated by automatic annotation. Virus Res. 2021 Aug 12:198545. Abstract
submitted by kickingbird at Aug, 20, 2021 from Virus Res. 2021 Aug 12:198545 (via https://www.sciencedirect.com/science/article/pii/S016817022)
The influenza A virus genome contains 8 gene segments encoding 10 commonly recognized proteins. Additional protein products have been identified including PB1-F2 and PA-X. We report in-silico identification ... Lagare A, Rajatonirina S, Testa J, Mamadou S. The epidemiology of seasonal influenza after the 2009 influenza pandemic in Africa: a systematic review. Afr Health Sci. 2020 Dec;20(4):1514-1536.. Abstract
submitted by kickingbird at Aug, 20, 2021 from Afr Health Sci. 2020 Dec;20(4):1514-1536. (via https://www.ajol.info/index.php/ahs/article/view/202264)
Background: Influenza infection is a serious public health problem that causes an estimated 3 to 5 million cases and 250,000 deaths worldwide every year. The epidemiology of influenza is well-documented ... 8183 items, 20/Page, Page[111/410][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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