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2019-5-20 13:34:47
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Takizawa N, et al. Local structural changes of the influenza A virus ribonucleoprotein complex by single mutations in the specific residues involved in efficient genome packaging. Virology. 2019 Mar 7;531:126-140.  Abstract  
submitted by kickingbird at Mar, 17, 2019 from Virology. 2019 Mar 7;531:126-140 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The influenza A virus genome consists of eight single-stranded negative-sense RNA segments. The noncoding regions located at the 3'- and 5'- ends of each segment are necessary for genome packaging, and ...

Beerens N, et al. Genetic relationship between poultry and wild bird viruses during the highly pathogenic avian influenza H5N6 epidemic in the Netherlands, 2017~2018. Transbound Emerg Dis. 2019 Mar 15.  Abstract  
submitted by kickingbird at Mar, 17, 2019 from Transbound Emerg Dis. 2019 Mar 15 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13169)
In the Netherlands, three commercial poultry farms and two hobby holdings were infected with highly pathogenic avian influenza (HPAI) H5N6 virus in the winter of 2017-2018. This H5N6 virus is a reassortant ...

Segaloff H, et al. Co-circulation of influenza A(H1N1)pdm09 and influenza A(H3N2) viruses, World Health Organization (WHO) European Region, October 2018 to February 2019. Euro Surveill. 2019 Feb;24(9)..  Abstract  
submitted by kickingbird at Mar, 16, 2019 from Euro Surveill. 2019 Feb;24(9). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In the World Health Organization European Region, the 2018/19 influenza season started in week 49 2018, crossing 10% virus-positivity in sentinel surveillance specimens. At week 5 2019, activity remained ...

Zhou AC, Batista NV, Watts TH. 4-1BB Regulates Effector CD8 T Cell Accumulation in the Lung Tissue through a TRAF1-, mTOR-, and Antigen-Dependent Mechanism to Enhance Tissue-Resident Memory T Cell Formation during Respiratory Influ. J Immunol. 2019 Mar 13..  Abstract  
submitted by kickingbird at Mar, 16, 2019 from J Immunol. 2019 Mar 13. (via http://www.jimmunol.org/content/early/2019/03/13/jimmunol.18)
The TNFR superfamily member 4-1BB is important in the establishment of tissue-resident memory T cells (Trm) in the lung tissue following influenza infection. Moreover, supraphysiological boosting of 4-1BB ...

Nuvey FS, et al. Evaluation of the sentinel surveillance system for influenza-like illnesses in the Greater Accra region, Ghana, 2018. PLoS One. 2019 Mar 14;14(3):e0213627.  Abstract  
submitted by kickingbird at Mar, 16, 2019 from PLoS One. 2019 Mar 14;14(3):e0213627 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
BACKGROUND: Influenza-like Illness (ILI) is a medical diagnosis of possible influenza or another respiratory illness with a common set of symptoms. The deaths of four schoolchildren, during a pandemic ...

Vilches TN, Jaberi-Douraki M, Moghadas SM. Risk of influenza infection with low vaccine effectiveness: the role of avoidance behaviour. Epidemiol Infect. 2019 Jan;147:e75..  Abstract  
submitted by kickingbird at Mar, 16, 2019 from Epidemiol Infect. 2019 Jan;147:e75. (via https://www.ncbi.nlm.nih.gov/pubmed/30869007)
Low vaccine-effectiveness has been recognised as a key factor undermining efforts to improve strategies and uptake of seasonal influenza vaccination. Aiming to prevent disease transmission, vaccination ...

Korsun NS, et al. Predominance of influenza B/Yamagata lineage viruses in Bulgaria during the 2017/2018 season. Epidemiol Infect. 2019 Jan;147:e76..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Epidemiol Infect. 2019 Jan;147:e76. (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
In this study, we investigated the antigenic and genetic characteristics of influenza viruses circulating in Bulgaria during the 2017/2018 season. The detection and typing/subtyping of influenza viruses ...

Siegers JY, et al. Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System. J Virol. 2019 Mar 13..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from J Virol. 2019 Mar 13. (via https://jvi.asm.org/content/early/2019/03/07/JVI.02273-18)
Central nervous system (CNS) disease is one of the most common extra-respiratory tract complication of influenza A virus infections. Remarkably, zoonotic H5N1 virus infections are more frequently associated ...

Alnaji FG, et al. Sequencing framework for the sensitive detection and precise mapping of defective interfering particle-associated deletions across influenza A and B viruses. J Virol. 2019 Mar 13..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from J Virol. 2019 Mar 13. (via https://jvi.asm.org/content/early/2019/03/07/JVI.00354-19)
The mechanisms and consequences of defective interfering particle (DIP) formation during influenza virus infection remain poorly understood. The development of next generation sequencing (NGS) technologies ...

Nogales A, et al. A novel fluorescent and bioluminescent Bi-Reporter influenza A virus (BIRFLU) to evaluate viral infections. J Virol. 2019 Mar 13.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from J Virol. 2019 Mar 13 (via https://jvi.asm.org/content/early/2019/03/07/JVI.00032-19)
Studying influenza A virus (IAV) requires the use of secondary approaches to detect the presence of virus in infected cells. To overcome this problem, we and others have generated recombinant IAV expressing ...

Lai JCC, et al. Neuraminidase activity and specificity of influenza A virus are influenced by haemagglutinin-receptor binding. Emerg Microbes Infect. 2019;8(1):327-338.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):327-338 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Influenza virus haemagglutinin (HA) and neuraminidase (NA) are involved in the recognition and modulation of sialic acids on the cell surface as the virus receptor. Although the balance between two proteins ...

Welkers MRA, et al. Genetic diversity and host adaptation of avian H5N1 influenza viruses during human infection. Emerg Microbes Infect. 2019;8(1):262-271..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):262-271. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
The continuing pandemic threat posed by avian influenza A/H5N1 viruses calls for improved insights into their evolution during human infection. We performed whole genome deep sequencing of respiratory ...

Monamele CG, et al. Evidence of exposure and human seroconversion during an outbreak of avian influenza A(H5N1) among poultry in Cameroon. Emerg Microbes Infect. 2019;8(1):186-196.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):186-196 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
From May 2016 to March 2017, 22 poultry outbreaks of avian influenza A(H5N1) were reported in Cameroon, mainly in poultry farms and live bird markets. No human cases were reported. In this study, we sought ...

Pan M, Yang HP, Jian J, et al. Association of meteorological factors with seasonal activity of influenza A subtypes and B lineages in subtropical western China. Epidemiol Infect. 2019 Jan;147:e72.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Epidemiol Infect. 2019 Jan;147:e72 (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
The seasonality of individual influenza subtypes/lineages and the association of influenza epidemics with meteorological factors in the tropics/subtropics have not been well understood. The impact of the ...

Amanat F, Meade P, Strohmeier S, Krammer F. Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model. Emerg Microbes Infect. 2019;8(1):155-168.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):155-168 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological ...

Bao L, et al. Diverse biological characteristics and varied virulence of H7N9 from Wave 5. Emerg Microbes Infect. 2019;8(1):94-102..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):94-102. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
There was a substantial increase with infections of H7N9 avian influenza virus (AIV) in humans during Wave 5 (2016-2017). To investigate whether H7N9 had become more infectious/transmissible and pathogenic ...

Schloer S, et al. The clinically licensed antifungal drug itraconazole inhibits influenza virus in vitro and in vivo. Emerg Microbes Infect. 2019;8(1):80-93..  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):80-93. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Influenza A virus (IAV) is a common pathogen of respiratory disease. The IAV-induced seasonal epidemics and the sporadic pandemics are associated with high morbidity and mortality. Therefore, effective ...

Yao Y, et al. Protection against homo and hetero-subtypic in?uenza A virus by optimized M2e DNA vaccine. Emerg Microbes Infect. 2019;8(1):45-54.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Emerg Microbes Infect. 2019;8(1):45-54 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2018.1)
Current influenza vaccines provide hemagglutinin strain-specific protection, but rarely provide cross-protection against divergent strains. It is, therefore, particularly important to develop a universal ...

Njifon HLM, et al. Genetic diversity of influenza A(H3N2) viruses in Northern Cameroon during the 2014-2016 influenza seasons. J Med Virol. 2019 Mar 13.  Abstract  
submitted by kickingbird at Mar, 15, 2019 from J Med Virol. 2019 Mar 13 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25456)
In Cameroon, genome characterization of influenza virus has been performed only in the Southern regions meanwhile genetic diversity of this virus varies with respect to locality. The Northern region characterized ...

Fritsch A, Schweiger B, Biere B. Influenza C virus in pre-school children with respiratory infections: retrospective analysis of data from the national influenza surveillance system in Germany, 2012 to 2014. Euro Surveill. 2019 Mar;24(10).  Abstract  
submitted by kickingbird at Mar, 15, 2019 from Euro Surveill. 2019 Mar;24(10) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
IntroductionRecent data on influenza C virus indicate a possible higher clinical impact in specified patient populations than previously thought.AimWe aimed to investigate influenza C virus circulation ...

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