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2020-3-31 17:30:23
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Shi L, et al. Molecular evolution and amino acid characteristics of newly isolated H9N2 avian influenza viruses from Liaoning Province, China. J Vet Med Sci. 2019 Dec 4..  Abstract  
submitted by kickingbird at Dec, 7, 2019 from J Vet Med Sci. 2019 Dec 4. (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_19)
H9N2 is widespread among poultry and humans. Though this subtype is not lethal to either species, it can cause considerable financial losses for farmers and threaten human health. In this study, 10 new ...

Chowdhury S, et al. The Pattern of Highly Pathogenic Avian Influenza H5N1 Outbreaks in South Asia. Trop Med Infect Dis. 2019 Nov 27;4(4)..  Abstract  
submitted by kickingbird at Dec, 2, 2019 from Trop Med Infect Dis. 2019 Nov 27;4(4). (via https://www.mdpi.com/2414-6366/4/4/138)
Highly pathogenic avian influenza (HPAI) H5N1 has caused severe illnesses in poultry and in humans. More than 15,000 outbreaks in domestic birds from 2005 to 2018 and 861 human cases from 2003 to 2019 ...

Ilyushina NA, et al. Influenza A virus hemagglutinin mutations associated with use of neuraminidase inhibitors correlate with decreased inhibition by anti-influenza antibodies. Virol J. 2019 Nov 29;16(1):149.  Abstract  
submitted by kickingbird at Dec, 2, 2019 from Virol J. 2019 Nov 29;16(1):149 (via https://www.ncbi.nlm.nih.gov/pubmed/31783761)
BACKGROUND: Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such ...

Mastrolia MV, Rubino C, Resti M, Trapani S, Galli. Characteristics and outcome of influenza-associated encephalopathy/encephalitis among children in a tertiary pediatric hospital in Italy, 2017-2019. BMC Infect Dis. 2019 Nov 29;19(1):1012.  Abstract  
submitted by kickingbird at Dec, 2, 2019 from BMC Infect Dis. 2019 Nov 29;19(1):1012 (via https://www.ncbi.nlm.nih.gov/pubmed/31783806)
BACKGROUND: Influenza is the most frequent cause of acute upper respiratory tract infections during winter season. Although rare, neurological manifestations are known to occur during influenza infection ...

Hibbs BF, et al. Reports of atypical shoulder pain and dysfunction following inactivated influenza vaccine, Vaccine Adverse Event Reporting System (VAERS), 2010-2017. Vaccine. 2019 Nov 26..  Abstract  
submitted by kickingbird at Dec, 2, 2019 from Vaccine. 2019 Nov 26. (via https://www.ncbi.nlm.nih.gov/pubmed/31784231)
BACKGROUND: Vaccines administered into or too close to underlying joint structures have the potential to cause shoulder injuries. Limited data exist on the epidemiology of such events.OBJECTIVE: To describe ...

Zhang Y, Yu T, Ding Y, Li Y, Lei J, Hu B, Zhou J. Analysis of Expression Profiles of Long Noncoding RNAs and mRNAs in A549 Cells Infected with H3N2 Swine Influenza Virus by RNA Sequencing. Virol Sin. 2019 Nov 27..  Abstract  
submitted by kickingbird at Dec, 1, 2019 from Virol Sin. 2019 Nov 27. (via https://www.ncbi.nlm.nih.gov/pubmed/31777011)
Long noncoding RNAs (lncRNAs) participate in regulating many biological processes. However, their roles in influenza A virus (IAV) pathogenicity are largely unknown. Here, we analyzed the expression profiles ...

Oliva J, et al. A murine model for the study of influenza D virus. J Virol. 2019 Nov 27..  Abstract  
submitted by kickingbird at Dec, 1, 2019 from J Virol. 2019 Nov 27. (via https://jvi.asm.org/content/early/2019/11/21/JVI.01662-19)
A novel genus within the Orthomyxoviridae family was identified in the USA and named Influenza D virus (IDV). Bovine have been proposed to be the primary host and three main viral lineages (D/OK-like, ...

Rodriguez-Frandsen A, et al. Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells. J Virol. 2019 Nov 27.  Abstract  
submitted by kickingbird at Dec, 1, 2019 from J Virol. 2019 Nov 27 (via https://jvi.asm.org/content/early/2019/11/21/JVI.01410-19)
Influenza A virus (IAV) is a human respiratory pathogen that causes yearly global epidemics, and sporadic pandemics due to human adaptation of pathogenic strains. Efficient replication of IAV in different ...

Karakus U, Pohl MO, Stertz S. Breaking the convention: Sialoglycan variants, Co-receptors and Alternative Receptors for Influenza A Virus Entry. J Virol. 2019 Nov 27..  Abstract  
submitted by kickingbird at Dec, 1, 2019 from J Virol. 2019 Nov 27. (via https://jvi.asm.org/content/early/2019/11/21/JVI.01357-19)
The influenza A virus (IAV) envelope protein haemagglutinin binds α2,6- or α2,3-linked sialic acid as host cell receptor. Bat IAV subtypes H17N10 and H18N11 form an exception to this rule and do not bind ...

Ding X, Yuan X, Mao L, Wu A, Jiang T. FluReassort: a database for the study of genomic reassortments among influenza viruses. Brief Bioinform. 2019 Nov 27.  Abstract  
submitted by kickingbird at Dec, 1, 2019 from Brief Bioinform. 2019 Nov 27 (via https://academic.oup.com/bib/advance-article-abstract/doi/10)
Genomic reassortment is an important genetic event in the generation of emerging influenza viruses, which can cause numerous serious flu endemics and epidemics within hosts or even across different hosts. ...

Khalaj-Hedayati A, Chua CLL, Smooker P, Lee KW. Nanoparticles in influenza subunit vaccine development: Immunogenicity enhancement. Influenza Other Respir Viruses. 2019 Nov 27.  Abstract  
submitted by kickingbird at Dec, 1, 2019 from Influenza Other Respir Viruses. 2019 Nov 27 (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12697)
The threat of novel influenza infections has sparked research efforts to develop subunit vaccines that can induce a more broadly protective immunity by targeting selected regions of the virus. In general, ...

Hanpaibool C, et al. Source of oseltamivir resistance due to single E119D and double E119D/H274Y mutations in pdm09H1N1 influenza neuraminidase. J Comput Aided Mol Des. 2019 Nov 26.  Abstract  
submitted by kickingbird at Dec, 1, 2019 from J Comput Aided Mol Des. 2019 Nov 26 (via https://www.ncbi.nlm.nih.gov/pubmed/31773463)
Influenza epidemics are responsible for an average of 3-5 millions of severe cases and up to 500,000 deaths around the world. One of flu pandemic types is influenza A(H1N1)pdm09 virus (pdm09H1N1). Oseltamivir ...

Haller O, Kochs G. Mx genes: host determinants controlling influenza virus infection and trans-species transmission. Hum Genet. 2019 Nov 26..  Abstract  
submitted by kickingbird at Dec, 1, 2019 from Hum Genet. 2019 Nov 26. (via https://www.ncbi.nlm.nih.gov/pubmed/31773252)
The human MxA protein, encoded by the interferon-inducible MX1 gene, is an intracellular influenza A virus (IAV) restriction factor. It can protect transgenic mice from severe IAV-induced disease, indicating ...

Wang Y, Song T, Li K, Jin Y, Yue J, Ren H, Liang L. Different Subtypes of Influenza Viruses Target Different Human Proteins and Pathways Leading to Different Pathogenic Phenotypes. Biomed Res Int. 2019 Oct 22;2019:4794910.  Abstract  
submitted by kickingbird at Dec, 1, 2019 from Biomed Res Int. 2019 Oct 22;2019:4794910 (via https://www.hindawi.com/journals/bmri/2019/4794910/)
Different subtypes of influenza A viruses (IAVs) cause different pathogenic phenotypes after infecting human bodies. Analysis of the interactions between viral proteins and the host proteins may provide ...

Park YR, et al. Genetic and pathogenic characteristics of clade 2.3.2.1c H5N1 highly pathogenic avian influenza viruses isolated from poultry outbreaks in Laos during 2015-2018. Transbound Emerg Dis. 2019 Nov 26..  Abstract  
submitted by kickingbird at Nov, 28, 2019 from Transbound Emerg Dis. 2019 Nov 26. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13430)
Since 2004, there have been multiple outbreaks of H5 highly pathogenic avian influenza (HPAI) viruses in Laos. Here, we isolated H5N1 HPAI viruses from poultry outbreaks in Laos during 2015-2018 and investigated ...

Putri L, et al. Co-circulation and characterization of HPAI-H5N1 and LPAI-H9N2 recovered from a duck farm, Yogyakarta, Indonesia. Transbound Emerg Dis. 2019 Nov 26..  Abstract  
submitted by kickingbird at Nov, 28, 2019 from Transbound Emerg Dis. 2019 Nov 26. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13434)
In July 2016, an avian influenza outbreak in duck farms in Yogyakarta province was reported to Disease Investigation Center (DIC) Wates, Indonesia with approximately 1,000 ducks death or culled. In this ...

Shin DL, et al. Highly Pathogenic Avian Influenza A(H5N8) Virus in Gray Seals, Baltic Sea. Emerg Infect Dis. 2019 Dec;25(12):2295-2298.  Abstract  
submitted by kickingbird at Nov, 25, 2019 from Emerg Infect Dis. 2019 Dec;25(12):2295-2298 (via https://wwwnc.cdc.gov/eid/article/25/12/18-1472_article)
We detected a highly pathogenic avian influenza A(H5N8) virus in lung samples of 2 gray seals (Halichoerus grypus) stranded on the Baltic coast of Poland in 2016 and 2017. This virus, clade 2.3.4.4 B, ...

Martelli P, et al. Influenza A(H1N1)pdm09 Virus Infection in a Captive Giant Panda, Hong Kong. Emerg Infect Dis. 2019 Dec;25(12):2303-2306..  Abstract  
submitted by kickingbird at Nov, 25, 2019 from Emerg Infect Dis. 2019 Dec;25(12):2303-2306. (via https://wwwnc.cdc.gov/eid/article/25/12/19-1143_article)
We report influenza A(H1N1)pdm09 virus infection in a captive giant panda in Hong Kong. The viral load peaked on day 1 and became undetectable on day 5, and an antibody response developed. Genome analysis ...

Fusade-Boyer M, et al. Evolution of Highly Pathogenic Avian Influenza A(H5N1) Virus in Poultry, Togo, 2018. Emerg Infect Dis. 2019 Dec;25(12):2287-2289.  Abstract  
submitted by kickingbird at Nov, 25, 2019 from Emerg Infect Dis. 2019 Dec;25(12):2287-2289 (via https://wwwnc.cdc.gov/eid/article/25/12/19-0054_article)
In 2015, highly pathogenic avian influenza A(H5N1) viruses reemerged in poultry in West Africa. We describe the introduction of a reassortant clade 2.3.2.1c virus into Togo in April 2018. Our findings ...

Susloparov IM, et al. Genetic Characterization of Avian Influenza A(H5N6) Virus Clade 2.3.4.4, Russia, 2018. Emerg Infect Dis. 2019 Dec;25(12):2338-2339..  Abstract  
submitted by kickingbird at Nov, 25, 2019 from Emerg Infect Dis. 2019 Dec;25(12):2338-2339. (via https://wwwnc.cdc.gov/eid/article/25/12/19-0504_article)
Timely identification of pandemic influenza threats depends on monitoring for highly pathogenic avian influenza viruses. We isolated highly pathogenic avian influenza A(H5N6) virus clade 2.3.4.4, genotype ...

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