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2024-3-28 18:00:34
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Hubbard LE, Givens CE, Stelzer EA, Killian ML, Kol. Environmental Surveillance and Detection of Infectious Highly Pathogenic Avian Influenza Virus in Iowa Wetlands. Environ Sci Technol Lett . 2023 Nov 15;10(12):1181.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Environ Sci Technol Lett . 2023 Nov 15;10(12):1181 (via https://pubs.acs.org/doi/10.1021/acs.estlett.3c00668)
Avian influenza viruses (AIVs) infect both wild birds and domestic poultry, resulting in economically costly outbreaks that have the potential to impact public health. Currently, a knowledge gap exists ...

Szablewski CM, McBride DS, Trock SC, Habing GG, Ho. Evolution of influenza A viruses in exhibition swine and transmission to humans, 2013-2015. Zoonoses Public Health. 2023 Dec 18.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Zoonoses Public Health. 2023 Dec 18 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13104)
Aims: Swine are a mixing vessel for the emergence of novel reassortant influenza A viruses (IAV). Interspecies transmission of swine-origin IAV poses a public health and pandemic risk. In the United States, ...

Sun X, Belser JA, Pulit-Penaloza JA, Brock N, Kier. A naturally occurring HA-stabilizing amino acid (HA1-Y17) in an A(H9N2) low-pathogenic influenza virus contributes to airborne transmission. mBio. 2023 Dec 19:e0295723.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from mBio. 2023 Dec 19:e0295723 (via https://journals.asm.org/doi/10.1128/mbio.02957-23)
Despite the accumulation of evidence showing that airborne transmissible influenza A virus (IAV) typically has a lower pH threshold for hemagglutinin (HA) fusion activation, the underlying mechanism for ...

Wen F, Wang C, Guo J, Yu H, Yuan S, Li Y, Li Z, Hu. Development and application of a triplex real-time PCR assay for the detection of H3, H4, and H5 subtypes of avian influenza virus. Poult Sci. 2023 Nov 30;103(2):103333.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Poult Sci. 2023 Nov 30;103(2):103333 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) poses a significant threat to the poultry industry and public health. Among the diverse AIV subtypes, H3, H4, and H5 are frequently detected in waterfowl and live poultry markets ...

Hu J, Zeng Z, Chen X, Zhang M, Hu Z, Gu M, Wang X,. Phosphorylation of PB2 at serine 181 restricts viral replication and virulence of the highly pathogenic H5N1 avian influenza virus in mice. Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4.  Abstract  
submitted by kickingbird at Dec, 18, 2023 from Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) still poses a pandemic threat to public health, causing a high mortality rate annually and during pandemic years. Posttranslational modification of the viral protein plays a substantial ...

Chenavier F, Estrozi LF, Teulon JM, Zarkadas E, Fr. Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv. 2023 Dec 15;9(50):eadj9974.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Sci Adv. 2023 Dec 15;9(50):eadj9974 (via https://www.science.org/doi/10.1126/sciadv.adj9974)
Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. Although ...

European Food Safety Authority (EFSA); Aznar I, Ko. Annual report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2022. EFSA J. 2023 Dec 14;21(12):e8480.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from EFSA J. 2023 Dec 14;21(12):e8480 (via https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa)
All European Union (EU) Member States (MSs) are required to implement surveillance for avian influenza (AI) in poultry and wild birds and (i) to notify the outbreaks, when relevant and (ii) to report the ...

Kapczynski DR, Chrzastek K, Shanmugasundaram R, Zs. Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virus. Virol J. 2023 Dec 15;20(1):298.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Virol J. 2023 Dec 15;20(1):298 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Avian influenza is a highly contagious, agriculturally relevant disease that can severely affect the poultry industry and food supply. Eurasian-origin H5Nx highly pathogenic avian influenza ...

Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saund. Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses. Cell Rep. 2023 Dec 13;42(12):113553.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Cell Rep. 2023 Dec 13;42(12):113553 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(23)015)
The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques ...

Li Y, Shang J, Luo J, Zhang F, Meng G, Feng Y, Jia. Rapid detection of H5 subtype avian influenza virus using CRISPR Cas13a based-lateral flow dipstick. Front Microbiol. 2023 Nov 29;14:1283210.  Abstract  
submitted by kickingbird at Dec, 15, 2023 from Front Microbiol. 2023 Nov 29;14:1283210 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1283)
Due to its high mortality rate, highly pathogenic avian influenza (HPAI), a notifiable animal illness designated by the World Organisation for Animal Health (WOAH), has caused enormous financial losses ...

Bialy D, Richardson S, Chrzastek K, Bhat S, Polo N. Recombinant A(H6N1)-H274Y avian influenza virus with dual drug resistance does not require permissive mutations to retain the replicative fitness in vitro and in ovo. Virology. 2023 Dec 2;590:109954.  Abstract  
submitted by kickingbird at Dec, 14, 2023 from Virology. 2023 Dec 2;590:109954 (via https://www.sciencedirect.com/science/article/pii/S004268222)
The possible emergence of drug-resistant avian flu raises concerns over the limited effectiveness of currently approved antivirals (neuraminidase inhibitors - NAIs) in the hypothetical event of a zoonotic ...

Zhou X, Lin Z, Tu J, Zhu C, Li H. Persistent predominance of the Victoria lineage of influenza B virus during COVID-19 epidemic in Nanchang, China. Influenza Other Respir Viruses. 2023 Dec 10;17(12).  Abstract  
submitted by kickingbird at Dec, 14, 2023 from Influenza Other Respir Viruses. 2023 Dec 10;17(12) (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13226)
he sentinel hospital-based influenza-like illness (ILI) surveillance network was established in China since the 2009 H1N1 pandemic. This network plays important roles in monitoring influenza virus variation ...

Trov?o NS, Khan SM, Lemey P, Nelson MI, Cherry JL. Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species. mBio. 2023 Dec 11:e0264923.  Abstract  
submitted by kickingbird at Dec, 12, 2023 from mBio. 2023 Dec 11:e0264923 (via https://journals.asm.org/doi/10.1128/mbio.02649-23)
For decades, researchers have studied the rapid evolution of influenza A viruses for vaccine design and as a useful model system for the study of host/parasite evolution. By performing an exhaustive analysis ...

Guan W, Qu R, Shen L, Mai K, Pan W, Lin Z, Chen L,. Baloxavir marboxil use for critical human infection of avian influenza A H5N6 virus. Med. 2023 Dec 5:S2666-6340(23)00361-6.  Abstract  
submitted by kickingbird at Dec, 11, 2023 from Med. 2023 Dec 5:S2666-6340(23)00361-6 (via https://www.cell.com/med/fulltext/S2666-6340(23)00361-6)
Background: Recent outbreaks of avian influenza and ongoing virus reassortment have drawn focus on spill-over infections. The increase in human infections with highly pathogenic avian influenza H5N6 virus ...

Lijuan Liang, etc.,al. Genetic variation and evolution of influenza viruses isolated from co-infection cases in Guangdong Province. DOI: 10.3760/cma.j.cn112309-20230717-00213.  Abstract  
submitted by kickingbird at Dec, 11, 2023 from DOI: 10.3760/cma.j.cn112309-20230717-00213 (via https://rs.yiigle.com/cmaid/1482234)
Objective To analyze and reveal the genetic evolution and variation of influenza viruses in cases of co-infection in Guangdong Province.Methods Throat swab samples were collected from four cases of H1N1pdm ...

Ly H. Highly pathogenic avian influenza H5N1 virus infection of companion animals. Virulence. 2024 Dec;15(1):2289780.  Abstract  
submitted by kickingbird at Dec, 10, 2023 from Virulence. 2024 Dec;15(1):2289780 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
While it is known that influenza viruses can frequently infect a variety of animal species, including humans (for a review, see ref., it is relatively uncommon for companion animals (e.g. pet cats and ...

Wang X, Zheng H, Gao R, Ren L, Jin M, Ji Z, Wang X. Genetically Related Avian Influenza H7N9 Viruses Exhibit Different Pathogenicity in Mice. Animals (Basel). 2023 Nov 28;13(23):3680.  Abstract  
submitted by kickingbird at Dec, 10, 2023 from Animals (Basel). 2023 Nov 28;13(23):3680 (via https://www.mdpi.com/2076-2615/13/23/3680)
Avian influenza viruses can cross species barriers and adapt to mammals. The H7N9 subtype AIV that emerged in China in 2013 caused 1568 human infections, with a mortality rate of nearly 40%. We conducted ...

Xianying Zeng, Guobin Tian, Hualan Chen. Progress in development and application of H5/H7 avian influenza vaccines in China. SCIENTIA SINICA Vitae.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from SCIENTIA SINICA Vitae (via doi:10.1360/SSV-2023-0144)
Since 1959,H5/H7 subtype avian influenza viruses(AIVs)have continued to endanger the development of the poultry industry and public health.In order to effectively control the H5/H7 subtype AIVs in poultry,China ...

Zhao W, Liu X, Zhang X, Qiu Z, Jiao J, Li Y, Gao R. Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations. Virulence. 2023 Dec;14(1):2250065.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from Virulence. 2023 Dec;14(1):2250065 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Clade 2.3.4.4 H5N6 avian influenza virus (AIV) has been predominant in poultry in China, and the circulating haemagglutinin (HA) gene has changed from clade 2.3.4.4h to clade 2.3.4.4b in recent years. ...

Caceres CJ, Gay LC, Faccin FC, Pérez DR. Use of Reverse Genetics for the Generation of Recombinant Influenza Viruses Carrying Nanoluciferase. Methods Mol Biol. 2024;2733:47-74.  Abstract  
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:47-74 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
Influenza A (FLUAV) and influenza B (FLUBV) viruses are human and/or animal pathogens widely studied due to their importance to public health and animal production. Both FLUAV and FLUBV possess a genome ...

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