Pelton SI, Divino V, Shah D, et al. Evaluating the Relative Vaccine Effectiveness of Adjuvanted Trivalent Influenza Vaccine Compared to High-Dose Trivalent and Other Egg-Based Influenza Vaccines among Older Adults in the US during the 2. Vaccines (Basel). 2020;8(3):E446. Abstract
submitted by kickingbird at Aug, 14, 2020 from Vaccines (Basel). 2020;8(3):E446 (via https://pubmed.ncbi.nlm.nih.gov/32784684/)
The influenza-related disease burden is highest among the elderly. We evaluated the relative vaccine effectiveness (rVE) of adjuvanted trivalent influenza vaccine (aTIV) compared to other egg-based influenza ...
Lim K, Kodera N, Wang H, et al. High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes. Nano Lett. 2020;10.1021/acs.nanolett.0c01755. Abstract
submitted by kickingbird at Aug, 14, 2020 from Nano Lett. 2020;10.1021/acs.nanolett.0c01755 (via https://pubmed.ncbi.nlm.nih.gov/32787163/)
Influenza A hemagglutinin (HA) is one of the crucial virulence factors that mediate host tropism and viral infectivity. Presently, the mechanism of the fusogenic transition of HA remains elusive. Here, ...
Jin L, Liu EM, Xie XH, Hu Y, Liao W. Comparative analysis of clinical features and risk factors of severe pneumonia development in pediatric patients hospitalized with seasonal influenza or swine-origin influenza infection. Adv Clin Exp Med. 2020;10.17219/acem/121520. Abstract
submitted by kickingbird at Aug, 14, 2020 from Adv Clin Exp Med. 2020;10.17219/acem/121520 (via https://pubmed.ncbi.nlm.nih.gov/32790248/)
Background: The influenza A virus is the most important human pathogen affecting respiratory tract in children and has been prevalent for more than a century. Objectives: To describe epidemiological and ...
Liang WS, He YC, Wu HD, et al. Ecological factors associated with persistent circulation of multiple highly pathogenic avian influenza viruses among poultry farms in Taiwan during 2015~17. PLoS One. 2020;15(8):e0236581. Abstract
submitted by kickingbird at Aug, 14, 2020 from PLoS One. 2020;15(8):e0236581 (via https://pubmed.ncbi.nlm.nih.gov/32790744/)
Emergence and intercontinental spread of highly pathogenic avian influenza A (HPAI) H5Nx virus clade 220.127.116.11 has resulted in substantial economic losses to the poultry industry in Asia, Europe, and North ...
Jurado-Tarifa E, Cano-Terriza D, Daly JM, Arenas A. Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain). Zoonoses Public Health. 2020;10.1111/zph.12758. Abstract
submitted by kickingbird at Aug, 12, 2020 from Zoonoses Public Health. 2020;10.1111/zph.12758 (via https://pubmed.ncbi.nlm.nih.gov/32772511/)
In April 2009, a new influenza A virus (IAV) subtype (A(H1N1)pdm09) spread worldwide and triggered the first human influenza pandemic of the 21st century. Since then, exposure to the pandemic H1N1 IAV ...
Liu K, Gao R, Wang X, et al. Pathogenicity and transmissibility of clade 18.104.22.168 highly pathogenic avian influenza virus subtype H5N6 in pigeons. Vet Microbiol. 2020;247:108776. Abstract
submitted by kickingbird at Aug, 10, 2020 from Vet Microbiol. 2020;247:108776 (via https://pubmed.ncbi.nlm.nih.gov/32768222/)
Pigeons were previously thought to be resistant to H5 viruses and to play a minimal role in spreading these viruses. In this study, we evaluated the pathogenicity of two clade 22.214.171.124 H5N6 viruses in pigeons ...
Lycett SJ, Pohlmann A, Staubach C, et al. Genesis and spread of multiple reassortants during the 2016/2017 H5 avian influenza epidemic in Eurasia. Proc Natl Acad Sci U S A. 2020;202001813. Abstract
submitted by kickingbird at Aug, 10, 2020 from Proc Natl Acad Sci U S A. 2020;202001813 (via https://pubmed.ncbi.nlm.nih.gov/32769208/)
Highly pathogenic avian influenza (HPAI) viruses of the H5 A/goose/Guangdong/1/96 lineage can cause severe disease in poultry and wild birds, and occasionally in humans. In recent years, H5 HPAI viruses ...
Yu CM, Chen IC, Tung CP, et al. A panel of anti-influenza virus nucleoprotein antibodies selected from phage-displayed synthetic antibody libraries with rapid diagnostic capability to distinguish diverse influenza virus subtypes. Sci Rep. 2020;10(1):13318. Abstract
submitted by kickingbird at Aug, 10, 2020 from Sci Rep. 2020;10(1):13318 (via https://pubmed.ncbi.nlm.nih.gov/32770098/)
Immunoassays based on sandwich immuno-complexes of capture and detection antibodies simultaneously binding to the target analytes have been powerful technologies in molecular analyses. Recent developments ...
Diallo AA, Souley MM, Issa Ibrahim A, et al. Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019. Transbound Emerg Dis. 2020;10.1111/tbed.13779. Abstract
submitted by kickingbird at Aug, 10, 2020 from Transbound Emerg Dis. 2020;10.1111/tbed.13779 (via https://pubmed.ncbi.nlm.nih.gov/32770642/)
Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina ...
Yu L, Pan J, Cao G, et al. AIV polyantigen epitope expressed by recombinant baculovirus induces a systemic immune response in chicken and mouse models. Virol J. 2020;17(1):121. Abstract
submitted by kickingbird at Aug, 8, 2020 from Virol J. 2020;17(1):121 (via https://pubmed.ncbi.nlm.nih.gov/32758272/)
Background: The protective efficacy of avian influenza virus (AIV) vaccines is unsatisfactory due to the presence of various serotypes generated by genetic reassortment. Thus, immunization with a polyantigen ...
Guo F, Yang J, Pan J, et al. Origin and Evolution of H1N1/pdm2009: A Codon Usage Perspective. Front Microbiol. 2020;11:1615. Abstract
submitted by kickingbird at Aug, 8, 2020 from Front Microbiol. 2020;11:1615 (via https://pubmed.ncbi.nlm.nih.gov/32760376/)
The H1N1/pdm2009 virus is a new triple-reassortant virus. While Eurasian avian-like and triple-reassortant swine influenza viruses are the direct ancestors of H1N1/pdm2009, the classic swine influenza ...
Wang S, Zheng Y, Jin X, et al. Efficacy and safety of a live attenuated influenza vaccine in Chinese healthy children aged 3-17 years in one study center of a randomized, double-blind, placebo-controlled phase 3 clinical trial, 201. Vaccine. 2020;S0264-410X(20)30932-4. Abstract
submitted by kickingbird at Aug, 5, 2020 from Vaccine. 2020;S0264-410X(20)30932-4 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Background: No data on the safety and efficacy of a live attenuated influenza vaccine in China have ever been reported. Methods: At a site of a phase 3 randomized, double-blind, placebo-controlled clinical ...
Zhou L, Feng Z, Liu J, et al. A single N342D substitution in influenza B Virus NA protein determines viral pathogenicity in mice. Emerg Microbes Infect. 2020;1-35. Abstract
submitted by kickingbird at Aug, 5, 2020 from Emerg Microbes Infect. 2020;1-35 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Influenza B virus (IBV) is one of the most important human respiratory viruses: it causes approximately one-third of the global influenza-related disease burden each year. However, compared with the several ...
Kim SH, Choi JW, Kim AR, Lee SC, Yoon MY. Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1. Biomolecules. 2020;10(8):E1116. Abstract
submitted by kickingbird at Aug, 2, 2020 from Biomolecules. 2020;10(8):E1116 (via https://pubmed.ncbi.nlm.nih.gov/32731467/)
Avian influenza (AI) has severely affected the poultry industry worldwide and has caused the deaths of millions of birds. Highly pathogenic avian influenza virus is characterized by high mortality and ...
Zhang M, Huang Y, Godson DL, Fernando C, Alexander. Assessment of Metagenomic Sequencing and qPCR for Detection of Influenza D Virus in Bovine Respiratory Tract Samples. Viruses. 2020;12(8):E814. Abstract
submitted by kickingbird at Aug, 2, 2020 from Viruses. 2020;12(8):E814 (via https://pubmed.ncbi.nlm.nih.gov/32731471/)
High throughput sequencing is currently revolutionizing the genomics field and providing new approaches to the detection and characterization of microorganisms. The objective of this study was to assess ...
Dharmayanti NLPI, Hewajuli DA, Ratnawati A, Hartaw. Genetic diversity of the H5N1 viruses in live bird markets, Indonesia. J Vet Sci. 2020;21(4):e56. Abstract
submitted by kickingbird at Aug, 2, 2020 from J Vet Sci. 2020;21(4):e56 (via https://pubmed.ncbi.nlm.nih.gov/32735094/)
Background: The live bird market (LBM) plays an important role in the dynamic evolution of the avian influenza H5N1 virus. Objectives: The main objective of this study was to monitor the genetic diversity ...
Yang F, Xu L, Liu F, Yao H, Wu N, Wu H. Development and evaluation of a TaqMan MGB RT-PCR assay for detection of H5 and N8 subtype influenza virus. BMC Infect Dis. 2020;20(1):550. Abstract
submitted by kickingbird at Jul, 31, 2020 from BMC Infect Dis. 2020;20(1):550 (via https://pubmed.ncbi.nlm.nih.gov/32727378/)
Background: Highly pathogenic influenza A (H5N8) viruses have caused several worldwide outbreaks in birds and are of potential risk to humans. Thus, a specific, rapid and sensitive method for detection ...
Xu Z, Zhou J, Huang Y, et al. Efficacy of convalescent plasma for the treatment of severe influenza. Crit Care. 2020;24(1):469. Abstract
submitted by kickingbird at Jul, 31, 2020 from Crit Care. 2020;24(1):469 (via https://pubmed.ncbi.nlm.nih.gov/32727526/)
Background: Convalescent plasma administration may be of clinical benefit in patients with severe influenza, but reports on the efficacy of this therapy vary. Methods: We conducted a systematic review ...
Hernandez-Mejia G, Hernandez-Vargas EA. Uncovering antibody cross-reaction dynamics in influenza A infections. Bioinformatics. 2020;btaa691. Abstract
submitted by kickingbird at Jul, 31, 2020 from Bioinformatics. 2020;btaa691 (via https://pubmed.ncbi.nlm.nih.gov/32730562/)
Motivation: Influenza viruses are a cause of large outbreaks and pandemics with high death tolls. A key obstacle is that flu vaccines have inconsistent performance, in the best cases up to 60% effectiveness, ...
Pulit-Penaloza JA, Brock N, Pappas C, et al. Characterization of highly pathogenic avian influenza H5Nx viruses in the ferret model. Sci Rep. 2020;10(1):12700. Abstract
submitted by kickingbird at Jul, 31, 2020 from Sci Rep. 2020;10(1):12700 (via https://pubmed.ncbi.nlm.nih.gov/32728042/)
Highly pathogenic avian influenza (HPAI) H5 viruses, of the A/goose/Guangdong/1/1996 lineage, have exhibited substantial geographic spread worldwide since the first detection of H5N1 virus in 1996. Accumulation ...
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