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2026-2-11 23:44:41
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Shu Zhou, Rute Maria Pinto, Hou Wei Chook, Eleanor. [preprint]Identification of cis-Acting Elements that Regulate Influenza A Virus Segment 7 Differential mRNA Splicing. https://doi.org/10.64898/2025.12.22.695654.  Abstract  
submitted by kickingbird at Dec, 23, 2025 from https://doi.org/10.64898/2025.12.22.695654 (via https://www.biorxiv.org/content/10.64898/2025.12.22.695654v1)
Influenza A virus segment 7 encodes the M1 matrix protein and M2 ion channel from an unspliced primary transcript mRNA1 and spliced mRNA2, respectively. Both proteins are essential for efficient virus ...

Gabriela J. Rzeszutek, etc.,al. [preprint]Zoonotic and Avian Pathogen Detections in Fecal and Sediment Samples - A Low-risk, High-throughput One Health Approach to Surveillance. https://doi.org/10.64898/2025.12.19.694637.  Abstract  
submitted by kickingbird at Dec, 23, 2025 from https://doi.org/10.64898/2025.12.19.694637 (via https://www.biorxiv.org/content/10.64898/2025.12.19.694637v1)
Many pathogens, both those with human spillover potential as well as avian-specific viruses, are maintained in wild bird populations. While much surveillance for influenza A viruses (IAVs) is performed ...

Niel KR, St Charles KM, Elissa JY, Lighty ME, Ssem. Highly Pathogenic Avian Influenza (HPAI H5N1, Clade 2.3.4.4b, genotype C2.1) in Commercial Ring-Necked Pheasants During the 2022 Outbreak in the United States. Can J Microbiol. 2025 Dec 22.  Abstract  
submitted by kickingbird at Dec, 23, 2025 from Can J Microbiol. 2025 Dec 22 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0198)
Highly pathogenic avian influenza (HPAI) virus H5N1 clade 2.3.4.4b was introduced into North America in 2021. In 2022, clade 2.3.4.4b spilled into domestic poultry in the United States (U.S.), resulting ...

St Charles KM, Ssematimba A, Bonney P, Cardona C. Evaluation of transmission metrics in a slow-spreading highly pathogenic avian influenza (HPAI) outbreak in a commercial upland game bird system. Can J Microbiol. 2025 Dec 22.  Abstract  
submitted by kickingbird at Dec, 23, 2025 from Can J Microbiol. 2025 Dec 22 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0203)
In 2022, highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b was detected in United States (US) poultry, quickly escalating into an outbreak that surpassed the 2014/15 HPAI US event in ...

Wang G, Gao X, Zhang G, Deng G, Shi J. Replication and Transmission of Influenza A Virus in Farmed Mink. Viruses. 2026; 18(1):9.  Abstract  
submitted by kickingbird at Dec, 22, 2025 from Viruses. 2026; 18(1):9 (via https://www.mdpi.com/1999-4915/18/1/9)
Farmed mink are frequently exposed to circulating influenza A viruses (IAVs), as confirmed by viral isolation and serological evidence. Previous work reveals that na?ve mink serve as susceptible hosts ...

Song Y, Song S, Yan A, Gong H, Yang H, Guan F, Zha. A Novel Recombinant Chicken-Derived H6N8 Subtype Avian Influenza Virus Caused Disease in Chickens and Mice. Viruses. 2026; 18(1):12.  Abstract  
submitted by kickingbird at Dec, 22, 2025 from Viruses. 2026; 18(1):12 (via https://www.mdpi.com/1999-4915/18/1/12)
H6 subtype avian influenza viruses (AIVs) have a broader host range and circulate globally in wild birds, domestic ducks, geese, and terrestrial poultry all over the world. Their demonstrated capacity ...

Lee N, Tang JW, Chon I, Kakuya F, Terao R, Kawashi. Influenza PA Substitutions and Genetic Diversity of A(H1N1)pdm09, A(H3N2), and B/Victoria Viruses in Japan During the 2023–2024 Season. Viruses. 2026; 18(1):13.  Abstract  
submitted by kickingbird at Dec, 22, 2025 from Viruses. 2026; 18(1):13 (via https://www.mdpi.com/1999-4915/18/1/13)
We characterized influenza A(H1N1)pdm09, A(H3N2), and B/Victoria viruses circulating in Japan during 2023–2024, focusing on lineage placement relative to WHO-recommended vaccine strains and on baloxavir ...

Zhang, L., Lai, Y., Cui, Y. et al. Emergence of mammalian-adaptive PB2 mutations enhances polymerase activity and pathogenicity of cattle-derived H5N1 influenza A virus. Nat Commun (2025).  Abstract  
submitted by kickingbird at Dec, 22, 2025 from Nat Commun (2025) (via https://www.nature.com/articles/s41467-025-67753-x)
Highly pathogenic avian influenza H5N1 poses an increasing public health risk, particularly following its spillover into dairy cows and associated human infections in the U.S. since March 2024. Here, we ...

Low, Y.S., Jauregui, R., Calcott, B. et al. Development of a portable avian influenza virus characterisation system: bringing the inside-out. Sci Rep (2025).  Abstract  
submitted by kickingbird at Dec, 21, 2025 from Sci Rep (2025) (via https://www.nature.com/articles/s41598-025-32771-8)
Highly pathogenic avian influenza (HPAI) poses a major threat to the world economy and human health; hence, rapid and accurate identification of avian influenza virus (AIV) subtypes is required for effective ...

Du, F., Zhang, Q., Cheng, Y. et al. A taxonomically harmonized global dataset of wild bird hosts for avian influenza virus surveillance. Sci Data (2025).  Abstract  
submitted by kickingbird at Dec, 21, 2025 from Sci Data (2025) (via https://www.nature.com/articles/s41597-025-06451-1)
Wild birds are key natural reservoirs and play a central role in the global spread of avian influenza viruses (AIVs). However, the absence of a standardized global list of wild bird hosts has limited comprehensive ...

El-Bidawy MH, Mohammad I, Ansari MR, Hajelbashir M. Highly Pathogenic Avian Influenza: Tracking the Progression from IAV (H5N1) to IAV (H7N9) and Preparing for Emerging Challenges. Microorganisms. 2026; 14(1):12.  Abstract  
submitted by kickingbird at Dec, 20, 2025 from Microorganisms. 2026; 14(1):12 (via https://www.mdpi.com/2076-2607/14/1/12)
Highly Pathogenic Avian Influenza (HPAI) viruses, particularly IAV (H5N1), continue to pose a major global threat due to their widespread circulation and high mortality rates in birds. Management of HPAI ...

Bedair, N.M., Sakr, M.A., Mourad, A. et al. Genetic characterization of highly pathogenic avian influenza A/H5N8 virus isolated from commercial poultry farms in Egypt reveals zoonotic potential. Arch Virol 171, 29 (2026).  Abstract  
submitted by kickingbird at Dec, 20, 2025 from Arch Virol 171, 29 (2026) (via https://link.springer.com/article/10.1007/s00705-025-06479-z)
Highly pathogenic avian influenza (HPAI) H5N8 virus, first identified in late 2016 in Egypt, continues to circulate and has replaced the previously dominant HPAI H5N1 virus of clade 2.2.1. In this study, ...

Adaszek ?, Domańska-Blicharz K, Jańczak D, Kalinow. Cats infected with H5N1 avian influenza - a new infectious disease in Poland. Pol J Vet Sci. 2025;28(4):683-689.  Abstract  
submitted by kickingbird at Dec, 20, 2025 from Pol J Vet Sci. 2025;28(4):683-689 (via https://journals.pan.pl/dlibra/publication/157284/edition/13)
Avian influenza virus (AIV) infections in cats are a new and not fully understood problem in Poland. These infections have drawn the attention of both veterinarians and human medical practitioners, mainly ...

Rogan A. Grant, etc.,al. [preprint]Influenza A infection accelerates disease-associated microglia formation during physiological aging. https://doi.org/10.64898/2025.12.11.693336.  Abstract  
submitted by kickingbird at Dec, 20, 2025 from https://doi.org/10.64898/2025.12.11.693336 (via https://www.biorxiv.org/content/10.64898/2025.12.11.693336v1)
Severe pneumonia is associated with an increased risk of cognitive decline and dementia, particularly in the elderly. Changes in microglia, the most abundant immune cell population in the brain, are also ...

Zhang, J., Xue, Q., Wang, X. et al. Chicken PIAS2 enhances H6N2 avian influenza virus replication by promoting SUMOylation of viral NP. Vet Res (2025).  Abstract  
submitted by kickingbird at Dec, 20, 2025 from Vet Res (2025) (via https://link.springer.com/article/10.1186/s13567-025-01702-w)
Avian influenza virus (AIV) is a significant zoonotic pathogen that causes infectious disease in various species and poses a serious threat to both the poultry industry and public health. Mammalian protein ...

Guan, X., Zhu, Z., Jiang, F. et al. Spatio-temporal patterns and associated factors of influenza-like illness outbreaks in Chinese mainland: a Bayesian modeling study. BMC Public Health (2025).  Abstract  
submitted by kickingbird at Dec, 20, 2025 from BMC Public Health (2025) (via https://link.springer.com/article/10.1186/s12889-025-25615-7)
Background: China is one of the regions with high incidence of influenza, previous researches have primarily focused on the seasonal characteristics, spatio-temporal distribution, and associated influencing ...

Chen, W., Pei, T., Zhang, Z. et al. Predicting host tropism in influenza a viruses: insights from multi-segment nucleotide signatures. J Transl Med (2025).  Abstract  
submitted by kickingbird at Dec, 20, 2025 from J Transl Med (2025) (via https://link.springer.com/article/10.1186/s12967-025-07569-x)
Background: Influenza A virus (IAV) poses a significant public health threat due to its cross-species transmission and complex host adaptation mechanisms. This study integrated whole-genome data from avian, ...

EFSA Panel on Animal Health and Welfare (AHAW). Risk of infection of dairy cattle in the EU with highly pathogenic avian influenza virus affecting dairy cows in the United States of America (H5N1, Eurasian lineage goose/Guangdong clade 2.3.4.4b. ge. EFSA Journal, Volume 23, Issue 12.  Abstract  
submitted by kickingbird at Dec, 19, 2025 from EFSA Journal, Volume 23, Issue 12 (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
This opinion assesses the risk of avian influenza H5N1 B3.13 genotype virus infection in EU dairy cattle. Introduction of the virus into EU dairy cattle, poultry or wild birds via trade or migratory birds ...

European Food Safety Authority (EFSA). Avian influenza overview September - November 2025. EFSA Journal, Volume 23, Issue 12.  Abstract  
submitted by kickingbird at Dec, 19, 2025 from EFSA Journal, Volume 23, Issue 12 (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
Between 6 September and 28 November 2025, 2896 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in domestic (442) and wild (2454) birds in 29 countries in Europe. The magnitude ...

Ferran Tarres-Freixas, etc.,al. [preprint]Airway organoids reveal patterns of Influenza A tropism and adaptation in wildlife species. https://doi.org/10.64898/2025.12.17.694819.  Abstract  
submitted by kickingbird at Dec, 19, 2025 from https://doi.org/10.64898/2025.12.17.694819 (via https://www.biorxiv.org/content/10.64898/2025.12.17.694819v1)
Identifying animal species that are susceptible to the plethora of existing and emerging viruses is critical for predicting and containing disease outbreaks. Current efforts to assess viral tropism largely ...

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