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2024-5-2 15:23:16
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Robert G. Webster and Elena A. Govorkova. H5N1 Influenza - Continuing Evolution and Spread. NEJM, 2006, 355(21):2174-7.  Full Text  
submitted by kickingbird at Dec, 21, 2006 from NEJM, 2006, 355(21):2174-7 (via http://content.nejm.org/cgi/content/full/355/21/2174)
There is no question that there will be another influenza pandemic someday. We simply don't know when it will occur or whether it will be caused by the H5N1 avian influenza virus. But given the number ...

Capua I, Marangon S. Control and prevention of avian influenza in an evolving scenario. Vaccine. 2006 Nov 9.  Abstract  
submitted by kickingbird at Dec, 20, 2006 from Vaccine. 2006 Nov 9 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Continuing outbreaks of highly pathogenic avian influenza (HPAI) across Eurasia and in Africa, caused by a type A influenza virus of the H5N1 subtype appear out of control and represent a serious risk ...

Shin YK, Liu Q, Tikoo SK, Babiuk LA, Zhou Y. Influenza A virus NS1 protein activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway by direct interaction with the p85 subunit of PI3K. J Gen Virol. 2007 Jan;88(Pt 1):13-8..  Abstract  
submitted by kickingbird at Dec, 20, 2006 from J Gen Virol. 2007 Jan;88(Pt 1):13-8. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Influenza A virus infection activates the phosphatidylinositol 3-kinase (PI3K)/Akt pathway, but the mechanism is not clear. Here, it is reported that influenza A virus NS1 protein is responsible for PI3K/Akt ...

Feng J, Zhang M, Mozdzanowska K, Zharikova D, Hoff. Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virol J. 2006 Dec 6;3(1):102.  Abstract  
submitted by kickingbird at Dec, 14, 2006 from Virol J. 2006 Dec 6;3(1):102 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
ABSTRACT: BACKGROUND: Matrix protein 2 (M2) is an integral tetrameric membrane protein of influenza A virus (IAV). Its ectodomain (M2e) shows remarkably little diversity amongst human IAV strains. As M2e-specific ...

Burleson GR, Burleson FG. fluenza virus host resistance model. Methods. 2007 Jan;41(1):31-7.  Abstract  
submitted by kickingbird at Dec, 14, 2006 from Methods. 2007 Jan;41(1):31-7 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Host resistance (HR) models are used to evaluate the effect of a test article on clearance of an infectious microorganism in order to assess total immunocompetence. HR models serve as biomarkers of net ...

Gabriel Sertsou, etc.,al. Key transmission parameters of an institutional outbreak during the 1918 influenza pandemic estimated by mathematical modelling. Theoretical Biology and Medical Modelling 2006, 3:.  Full Text  
submitted by kickingbird at Dec, 7, 2006 from Theoretical Biology and Medical Modelling 2006, 3: (via http://www.tbiomed.com/content/3/1/38)
Aim: To estimate the key transmission parameters associated with an outbreak of pandemic influenza in an institutional setting (New Zealand 1918). Methods Historical morbidity and mortality data were ...

Alexander DJ.. An overview of the epidemiology of avian influenza. Vaccine. 2006 Nov 9.  Abstract  
submitted by kickingbird at Dec, 7, 2006 from Vaccine. 2006 Nov 9 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
Only viruses of the Influenzavirus A genus have been isolated from birds and termed avian influenza [AI] viruses, but viruses with all 16 haemagglutinin [H1-H16] and all 9 neuraminidase [N1-N9] influenza ...

Baz M, Abed Y, Boivin G. Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir. Antiviral Res. 2006 Nov 20.  Abstract  
submitted by kickingbird at Dec, 7, 2006 from Antiviral Res. 2006 Nov 20 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d)
There is a limited information with regard to the neuraminidase (NA) mutations conferring resistance to peramivir and zanamivir in the influenza N1 background. In this study, an influenza A/WSN/33 (H1N1) ...

Harris A, Cardone G, Winkler DC, Heymann JB, Brech. Influenza virus pleiomorphy characterized by cryoelectron tomography. Proc Natl Acad Sci U S A. 2006 Dec 4.  Abstract  
submitted by kickingbird at Dec, 7, 2006 from Proc Natl Acad Sci U S A. 2006 Dec 4 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Influenza virus remains a global health threat, with millions of infections annually and the impending threat that a strain of avian influenza may develop into a human pandemic. Despite its importance ...

Uchide N, Ohyama K, Bessho T, Toyoda H. Effects of Mitogen-Activated Protein Kinase Inhibitors on Tumor Necrosis Factor-alpha Gene Expression and Apoptosis Induction in Cultured Human Fetal Membrane Chorion Cells Infected with Influenza Vir. Intervirology. 2006 Nov 30;50(2):99-107.  Abstract  
submitted by kickingbird at Dec, 4, 2006 from Intervirology. 2006 Nov 30;50(2):99-107 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
We investigated the involvement of p38 mitogen-activated protein (MAP) kinase in tumor necrosis factor (TNF)-alpha gene expression, apoptosis induction and virus replication in cultured human fetal membrane ...

Shiratsuchi A, Nakanishi Y. Elimination of Influenza Virus-infected Cells by Phagocytosis. Yakugaku Zasshi. 2006 Dec;126(12):1245-51.  Abstract  
submitted by kickingbird at Dec, 4, 2006 from Yakugaku Zasshi. 2006 Dec;126(12):1245-51 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Infection with a variety of viruses induces apoptosis in host cells. This phenomenon may be considered to be a self-defense mechanism to avoid viral propagation. However, the growth of influenza virus ...

Luciana L. Borio. CBN Report: Avian Influenza A (H5N1) Infection in Humans in Turkey, 2006. CBN.  Abstract  
submitted by kickingbird at Dec, 1, 2006 from CBN (via www.upmc-cbn.org)
This week in the New England Journal of Medicine (NEJM), Oner and colleagues describe the epidemiologic, clinical, and radiologic features of an outbreak of highly pathogenic avian influenza ...

Zheng M, Yu K, Liu H, Luo X, Chen K, Zhu W, Jiang. QSAR analyses on avian influenza virus neuraminidase inhibitors using CoMFA, CoMSIA, and HQSAR. J Comput Aided Mol Des. 2006 Sep;20(9):549-66..  Abstract  
submitted by kickingbird at Nov, 28, 2006 from J Comput Aided Mol Des. 2006 Sep;20(9):549-66. (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
The recent wide spreading of the H5N1 avian influenza virus (AIV) in Asia, Europe and Africa and its ability to cause fatal infections in human has raised serious concerns about a pending global flu pandemic. ...

Feare CJ, Yasue M.. Asymptomatic infection with highly pathogenic avian influenza H5N1 in wild birds: how sound is the evidence?. Virol J. 2006 Nov 17;3(1):96 [Epub ahead of print].  Abstract  
submitted by kickingbird at Nov, 28, 2006 from Virol J. 2006 Nov 17;3(1):96 [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
ABSTRACT: BACKGROUND: Widespread deaths of wild birds from which highly pathogenic avian influenza virus H5N1 has been isolated suggest that the virus continues to be lethal to them. However, asymptomatic ...

Nagy A, Machova J, Hornickova J, Tomci M, Nagl I. Highly pathogenic avian influenza virus subtype H5N1 in Mute swans in the Czech Republic. Vet Microbiol. 2006 Oct 12; [Epub ahead of print].  Abstract  
submitted by kickingbird at Nov, 28, 2006 from Vet Microbiol. 2006 Oct 12; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
In order to determine the actual prevalence of avian influenza viruses (AIV) in wild birds in the Czech Republic extensive surveillance was carried out between January and April 2006. A total of 2101 samples ...

Dwyer DE, Smith DW, Catton MG, Barr IG. Laboratory diagnosis of human seasonal and pandemic influenza virus infection. Med J Aust. 2006 Nov 20;185(10):S48-53.  Abstract  
submitted by kickingbird at Nov, 28, 2006 from Med J Aust. 2006 Nov 20;185(10):S48-53 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Laboratory diagnosis is important to distinguish influenza from other respiratory virus infections. It will be especially important in detecting the first cases of pandemic influenza. Good quality respiratory ...

Barr IG, Komadina N, Durrant C, Sjogren H, Hurt AC. Circulation and antigenic drift in human influenza B viruses in SE Asia and Oceania since 2000. Commun Dis Intell. 2006;30(3):350-7.  Abstract  
submitted by kickingbird at Nov, 28, 2006 from Commun Dis Intell. 2006;30(3):350-7 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
During annual influenza epidemics, influenza B viruses frequently co-circulate with influenza A viruses and in some years, such as 2005, large outbreaks have occurred while in other years, the virus virtually ...

Naito T, Momose F, Kawaguchi A, Nagata K. Involvement of Hsp90 in assembly and nuclear import of the influenza virus RNA polymerase subunits. J Virol. 2006 Nov 22; [Epub ahead of print].  Abstract  
submitted by kickingbird at Nov, 28, 2006 from J Virol. 2006 Nov 22; [Epub ahead of print] (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Transcription and replication of the influenza virus RNA genome occur in the nuclei of infected cells through the viral RNA-dependent RNA polymerase consisting of PB1, PB2, and PA. We previously identified ...

Kuk Kwon Y, Jeong Lee Y, Gu Choi J, Kyoung Lee E,. An outbreak of avian influenza subtype H9N8 among chickens in South Korea. Avian Pathol. 2006 Dec;35(6):443-7.  Abstract  
submitted by kickingbird at Nov, 28, 2006 from Avian Pathol. 2006 Dec;35(6):443-7 (via http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=)
Low pathogenic avian influenza subtype H9N8 was diagnosed on a Korean native chicken farm in Gyeonggi province, South Korea, in late April 2004. Clinical signs included moderate respiratory distress, depression, ...

CSR. WHO guidelines for investigation of human cases of avian influenza A(H5N1). WHO.  Abstract  
submitted by kickingbird at Nov, 28, 2006 from WHO (via http://www.who.int/csr/resources/publications/influenza/WHO_)
Contents- Introduction- Purpose and scope of the document- Objectives for investigations of human cases of A(H5N1)- Initiating an investigation - Key steps for investigation of human cases of A(H5N1)- ...

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