Holly J, Fogelova M, Jakubcova L, Tomcikova K, et. Comparison of infectious influenza A virus quantification methods employing immuno-staining. J Virol Methods 2017 Jun 10. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Virol Methods 2017 Jun 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28610903/)
Infections caused by highly variable influenza A viruses (IAVs) pose perpetual threat to humans as well as to animals. Their surveillance requires reliable methods for their qualitative and quantitative ... Magnen M, Gueugnon F, Guillon A, Baranek T, et al. Kallikrein-related peptidase 5 contributes to H3N2 influenza virus infection in human lungs. J Virol 2017 Jun 14. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Virol 2017 Jun 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28615200/)
The HA (hemagglutinin) of influenza virus must be activated by proteolysis before the virus can become infectious. Previous studies have indicated that HA cleavage is driven by membrane-bound or extracellular ... Mogling R, Richard MJ, Vliet SV, Beek RV, et al. Neuraminidase-mediated haemagglutination of recent human influenza A(H3N2) viruses is determined by arginine 150 flanking the neuraminidase catalytic site. Gen Virol 2017 Jun 13. Abstract
submitted by kickingbird at Jun, 18, 2017 from Gen Virol 2017 Jun 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28612701/)
Over the last decade, an increasing proportion of circulating human influenza A(H3N2) viruses exhibited haemagglutination activity that was sensitive to neuraminidase inhibitors. This change in haemagglutination ... Leymarie O, Meyer L, Tafforeau L, Lotteau V, et al. Influenza virus protein PB1-F2 interacts with CALCOCO2 (NDP52) to modulate innate immune response. J Gen Virol 2017 Jun 14. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Gen Virol 2017 Jun 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28613140/)
PB1-F2 is a viral protein encoded by influenza A viruses (IAVs). PB1-F2 is implicated in virulence by triggering immune cell apoptosis and enhancing inflammation. To obtain an insight into the molecular ... Abdul-Cader MS, Ahmed-Hassan H, Amarasinghe A, Nag. Toll-like receptor (TLR)21 signalling-mediated antiviral response against avian influenza virus infection correlates with macrophage recruitment and nitric oxide production. J Gen Virol 2017 Jun 14. Abstract
submitted by kickingbird at Jun, 18, 2017 from J Gen Virol 2017 Jun 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28613150/)
Cytosine-guanosinedeoxynucleotide (CpG) DNA can be used for the stimulation of the toll-like receptor (TLR)21 signalling pathway in avian species which ultimately leads to up-regulation of gene transcription ... Nicholas C. Wu, etc.,al. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host&Microbe Volume 21, Issue 6, p742–753. Abstract
submitted by kickingbird at Jun, 16, 2017 from Cell Host&Microbe Volume 21, Issue 6, p742–753 (via http://www.cell.com/cell-host-microbe/fulltext/S1931-3128(17)
Influenza A virus hemagglutinin (HA) initiates viral entry by engaging host receptor sialylated glycans via its receptor-binding site (RBS). The amino acid sequence of the RBS naturally varies across ... Benjamin M. Tang, Maryam Shojaei,etc.,al. A novel immune biomarker IFI27 discriminates between influenza and bacteria in patients with suspected respiratory infection. European Respiratory Journal 2017 49: 1602098. Abstract
submitted by kickingbird at Jun, 16, 2017 from European Respiratory Journal 2017 49: 1602098 (via http://erj.ersjournals.com/content/49/6/1602098)
Host response biomarkers can accurately distinguish between influenza and bacterial infection. However, published biomarkers require the measurement of many genes, thereby making it difficult to implement ... de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X,. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog 13(6): e1006390.. Abstract
submitted by kickingbird at Jun, 16, 2017 from PLoS Pathog 13(6): e1006390. (via http://journals.plos.org/plospathogens/article?id=10.1371/jo)
The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of human H7N9 isolates contained a hemagglutinin ... Ninpan K, Suptawiwat O, Boonarkart C, Songprakhon. Mutations in Matrix Protein 1 and Nucleoprotein caused Human-Specific Defects in Nuclear Exportation and Viral Assembly of an Avian Influenza H7N1 Virus. Virus Res 2017 Jun 1. Abstract
submitted by kickingbird at Jun, 13, 2017 from Virus Res 2017 Jun 1 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28579356/)
Nuclear exportation of influenza ribonucleoprotein is a vital step in viral replication cycle. In this study a particular H7N1 (A/ostrich/Zimbabwe/222-E3/1996) virus showed exclusively nuclear localization ... Manito ACB, Graf T, Lunge VR, Ikuta N, et al.. Spatiotemporal dynamics of influenza A(H1N1)pdm09 in Brazil during the pandemic and post-pandemic periods. Virus Res 2017 Jun 3. Abstract
submitted by kickingbird at Jun, 13, 2017 from Virus Res 2017 Jun 3 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28587867/)
Influenza A(H1N1)pdm09 was responsible for the first global flu pandemic in 21st century affecting all the world. In Brazil, A(H1N1)pdm09 is still circulating as a seasonal virus, causing deaths every ... Kurupati RK, Kossenkoff A, Kannan S, Haut LH, et a. The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged. Vaccine 2017 Jun 2. Abstract
submitted by kickingbird at Jun, 13, 2017 from Vaccine 2017 Jun 2 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28583307/)
Antibody responses, B cell subset distribution in blood and the blood transcriptome were analyzed in younger and aged human subjects before and after vaccination with the inactivated influenza vaccine. ... Vijayan M, Xia C, Song YE, Ngo H, et al.. Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. J Immunol 2017 Jun 9. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Immunol 2017 Jun 9 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28600291/)
Sphingosine 1-phosphate (S1P) lyase (SPL) is an intracellular enzyme that mediates the irreversible degradation of the bioactive lipid S1P. We have previously reported that overexpressed SPL displays anti-influenza ... Naguib MM, Grund C, Arafa AS, Abdelwhab EM, et al. Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not. J Gen Virol 2017 Jun 5. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Gen Virol 2017 Jun 5 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28590242/)
In Egypt, zoonotic A/goose/Guangdong/1/96 (gs/GD-like) highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.2.1.2 is entrenched in poultry populations and has co-circulated with low-pathogenic ... Zhang X, Xu G, Wang C, Jiang M, et al.. Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations. J Gen Virol 2017 Jun 8. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Gen Virol 2017 Jun 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28597818/)
The H10 subtype of avian influenza viruses (AIVs) circulates globally in wild birds and poultry, and this subtype has been shown to be increasingly prevalent in China. Among the various H10 viruses, H10N7 ... Yamashita N, Yashiro M, Ogawa H, Namba H, et al. Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells. Biochem Biophys Res Commun 2017 May 30. Abstract
submitted by kickingbird at Jun, 13, 2017 from Biochem Biophys Res Commun 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28576495/)
Our previous analysis of gene expression profiles in the peripheral blood from patients with influenza A (H1N1) pdm09 pneumonia revealed elevated transcription levels of the vanin-1 (vascular non-inflammatory ... Zhang ZH, Meng LS, Kong DH, Liu J, Li SZ, Zhou C,. A Suspected Person-to-person Transmission of Avian Influenza A (H7N9) Case in Ward. Chin Med J 2017 Jun 6. Abstract
submitted by kickingbird at Jun, 7, 2017 from Chin Med J 2017 Jun 6 (via http://www.cmj.org/text.asp?2017/130/10/1255/205849)
Since throat swab specimens obtained from three adult Chinese patients were confirmed as an avian-origin influenza A (H7N9) virus by local Centers for Disease Control and Prevention (CDC) in 2013,[1] many ... X Wang, etc.,al. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013~17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis. Abstract
submitted by kickingbird at Jun, 6, 2017 from Lancet Infect Dis (via http://www.thelancet.com/journals/laninf/article/PIIS1473-30)
Summary
Background
The avian influenza A H7N9 virus has caused infections in human beings in China since 2013. A large epidemic in 2016–17 prompted concerns that the epidemiology of the virus might ... Wang BX, Brown EG, Fish EN. Residues F103 and M106 within the influenza A virus NS1 CPSF4-binding region regulate interferon-stimulated gene translation initiation. Virology 2017;508:170-179. Abstract
submitted by kickingbird at Jun, 5, 2017 from Virology 2017;508:170-179 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554059/)
Influenza A virus (IAV) non-structural protein 1 (NS1) suppresses host innate immune responses by inhibiting type I interferon (IFN) production. We provide evidence that residues F103 and M106 in the CPSF4-binding ... Bertran K, Balzli C, Lee DH, Suarez DL, et al. Protection of White Leghorn chickens by U.S. emergency H5 vaccination against clade 2.3.4.4 H5N2 high pathogenicity avian influenza virus. Vaccine 2017 May 26. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 26 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554502/)
During December 2014-June 2015, the U.S. experienced a high pathogenicity avian influenza (HPAI) outbreak caused by clade 2.3.4.4 H5Nx Goose/Guangdong lineage viruses with devastating consequences for ... Petiot E, Proust A, Traversier A, Durous L, et al. Influenza viruses production: Evaluation of a novel avian cell line DuckCelt-T17. Vaccine 2017 May 29. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28571695/)
The influenza vaccine manufacturing industry is looking for production cell lines that are easily scalable, highly permissive to multiple viruses, and more effective in term of viral productivity. One ... 7473 items, 20/Page, Page[231/374][|<<] [|<] [231] [232] [233] [234] [235] [236] [237] [238] [239] [240] [>|] [>>|] |
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