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2026-4-18 17:04:05
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M. Odin, F. Schmeisser, J. Soto, and J. P. Weir. A Monoclonal Antibody ELISA–Based Assay for Measuring the Potency of Candidate H5 Clade 2.3.4.4b Pandemic Influenza Vaccines. Influenza and Other Respiratory Viruses 20, no. 3.  Abstract  
submitted by kickingbird at Feb, 26, 2026 from Influenza and Other Respiratory Viruses 20, no. 3 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70206)
BackgroundThe single radial immunodiffusion (SRID) assay is used to determine the potency of inactivated influenza vaccines. Nevertheless, development of alternative influenza vaccine potency assays with ...

Farrell ML, McGrath G, Cuartero LG, Barry G. Avian influenza in Ireland: a spatiotemporal, subtype and host-based analysis (1983-2024). J Gen Virol. 2026 Feb;107(2).  Abstract  
submitted by kickingbird at Feb, 26, 2026 from J Gen Virol. 2026 Feb;107(2) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Avian influenza virus (AIV) is a significant global concern, causing widespread mortality in wild birds, domestic poultry and, more recently, wild and domestic mammals. This study presents a retrospective ...

Jerome S. Leonard, etc.,al. [preprint]Influenza Vaccine Effectiveness Against Pediatric Deaths: 2016-2025. https://doi.org/10.64898/2026.02.20.26346732.  Abstract  
submitted by kickingbird at Feb, 25, 2026 from https://doi.org/10.64898/2026.02.20.26346732 (via https://www.medrxiv.org/content/10.64898/2026.02.20.26346732)
BACKGROUND AND OBJECTIVES Seasonal influenza vaccination has been shown to reduce the risk of influenza and severe complications among children 6 months and older. Since 2010, reported numbers of influenza-associated ...

Park, Sh., Lee, SH., Seo, YR. et al. Evolution and spread of H8Nx avian influenza viruses from wild birds in East Asia, 2019-2024. Arch Virol 171, 95 (2026).  Abstract  
submitted by kickingbird at Feb, 25, 2026 from Arch Virol 171, 95 (2026) (via https://link.springer.com/article/10.1007/s00705-026-06579-4)
Subtype H8 avian influenza viruses (AIVs) are rarely reported and poorly characterized. We isolated nine H8Nx AIVs from wild birds in South Korea during 2019-2024. Whole-genome and phylogenetic analyses ...

Ra Mi Cha, etc.,al. Emergence and Genetic Characteristics of H5N1, H5N6, and H5N3 Clade 2.3.4.4b High Pathogenicity Avian Influenza Viruses in South Korea During the 2023-2024 and 2024-2025 Winter Seasons. Transboundary and Emerging Diseases.  Abstract  
submitted by kickingbird at Feb, 25, 2026 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/8053623)
Since 2020, clade 2.3.4.4b H5Nx high pathogenicity avian influenza viruses (HPAIVs) have consistently spread across continents, causing outbreaks worldwide. During the 2023–2024 (23/24) and 2024–2025 (24/25) ...

Zhang N, Chang B, Lin R, Lin X, Tang J, Xiao S. Bidirectional transfer of influenza virus between hands and environmental surfaces under multifactorial conditions. Int J Hyg Environ Health. 2026 Feb 22;273:114766.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Int J Hyg Environ Health. 2026 Feb 22;273:114766 (via https://www.sciencedirect.com/science/article/abs/pii/S14384)
Influenza viruses continue to circulate worldwide, posing persistent challenges to public health. Indirect contact transmission (i.e., transmission via contaminated surfaces, or fomites) is a recognized ...

Dalesio EW, Cheng TY, Bowman AS, Ochwo S, Schambow. Field performance of a point-of-care PCR platform for the detection of influenza A virus in growing pigs. Vet Anim Sci. 2026 Feb 11;32:100594.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Vet Anim Sci. 2026 Feb 11;32:100594 (via https://www.sciencedirect.com/science/article/pii/S2451943X2)
Point-of-care (POC) testing involves conducting diagnostic assays near patients to enable rapid decision-making and timely intervention. To date, evaluation of POC devices under field conditions in veterinary ...

Kong JD, Gillies M, Gardner E, Bragazzi NL. Multi-model large-scale AI framework for avian influenza surveillance and preparedness: Harnessing large language models to enhance risk communication, real-time decision support, and public health re. One Health. 2026 Feb 10;22:101357.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from One Health. 2026 Feb 10;22:101357 (via https://www.sciencedirect.com/science/article/pii/S235277142)
Avian influenza remains a persistent threat to global health security, with serious consequences for food systems, trade, and pandemic preparedness. To address gaps in public health communication and stakeholder-specific ...

Feng T, Huang Y, Luo C. SpecFlu-Net: A frequency-aware neural architecture with temporal-dependency optimization for long-term seasonal influenza transmission forecasting. Infect Med (Beijing). 2026 Jan 17;5(1):100236.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Infect Med (Beijing). 2026 Jan 17;5(1):100236 (via https://www.sciencedirect.com/science/article/pii/S2772431X2)
Background: Seasonal influenza poses severe global health and economic burdens, demanding reliable long-term (3-6 months) forecasts for proactive public-health interventions. However, influenza surveillance ...

Wenger GK, Snyder DT, Prigge JR, Turner AH, Jaffra. Primary bovine embryonic fibroblasts demonstrate variable fitness following infection with highly pathogenic avian influenza H5N1 strains and are susceptible to a recently circulating human 2009 pande. Microbiol Spectr 0:e03285-25.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Microbiol Spectr 0:e03285-25 (via https://journals.asm.org/doi/10.1128/spectrum.03285-25)
The recent emergence of highly pathogenic avian influenza (HPAI) H5N1 (clade 2.3.4.4b, genotype B3.13) in dairy cattle presents substantial challenges to the agricultural sector and public health. Mechanistic ...

Charlotte Kristiane Hjulsager, Yuan Liang, Casper. Mass mortalities caused by different genotypes of HPAIV H5N1 clade 2.3.4.4b in colony breeding Black-headed Gulls and Sandwich Terns in Denmark 2022 and 2023. Canadian Journal of Microbiology, Vol 72, 2026.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Canadian Journal of Microbiology, Vol 72, 2026 (via https://www.sciencedirect.com/org/science/article/pii/S00084)
Unprecedented seabird mass mortality events (MMEs) were reported in multiple European countries in 2022 and 2023. These events were attributed to Clade 2.3.4.4b H5N1 high pathogenicity avian influenza ...

Susannah Gold, Bart Donato, Vivienne Booth. Evaluating the effectiveness of carcass removal to mitigate highly pathogenic avian influenza outbreaks in ground-nesting bird colonies: A modelling approach. Ecological Solutions and Evidence, 7, e70185.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Ecological Solutions and Evidence, 7, e70185 (via https://besjournals.onlinelibrary.wiley.com/doi/10.1002/2688)
Since 2020, impacts of highly pathogenic avian influenza (HPAI) on wild bird populations have escalated globally. Colonial nesting birds are particularly vulnerable, as high-density colonies facilitate ...

Steinfurth, A., Lynton-Jenkins, J. G., Cleeland, J. Investigating high pathogenicity avian influenza virus incursions to remote islands: detection of H5N1 on Gough Island in the South Atlantic Ocean. Emerging Microbes & Infections, 15(1).  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Emerging Microbes & Infections, 15(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ...

Son DH, Balupuri A, Nam JH, Kim IH, Choi YJ, An BM. Analyses of receptor binding specificity of highly pathogenic avian influenza a (H5N1) viruses isolated from felines in South Korea, 2023. Virulence. 2026 Feb 23:2636350.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Virulence. 2026 Feb 23:2636350 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2026.2)
Influenza viruses infect host cells by binding to specific sialic acid receptors present on the surface of target cells, and this receptor binding exhibits specificity depending on cell type and host species. ...

Kikawa C, Loes AN, Huddleston J, Figgins MD, Stein. High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains. Elife. 2026 Feb 23;14:RP106811.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Elife. 2026 Feb 23;14:RP106811 (via https://elifesciences.org/articles/106811)
Human influenza viruses rapidly acquire mutations in their hemagglutinin (HA) protein that erode neutralization by antibodies from prior exposures. Here, we use a sequencing-based assay to measure neutralization ...

Miller J, Diefenbach-Elstob T, Wordsworth R, Deshp. Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza during 2024. Commun Dis Intell (2018). 2026 Feb 24;50.  Abstract  
submitted by kickingbird at Feb, 24, 2026 from Commun Dis Intell (2018). 2026 Feb 24;50 (via https://ojs.cdi.cdc.gov.au/index.php/cdi/article/view/3449)
As part of its role in the World Health Organization (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne received ...

Caroline Kikawa, etc.,al. [preprint]Near real-time data on the human neutralizing antibody landscape to influenza virus as of early 2026 to inform vaccine-strain selection. https://doi.org/10.64898/2026.02.18.706711.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.18.706711 (via https://www.biorxiv.org/content/10.64898/2026.02.18.706711v1)
Twice each year, a decision is made on whether to update the strains included in the seasonal influenza vaccine to better match the most recent circulating viral strains. To characterize the antigenic ...

Liping Wang, etc.,al. [preprint]Vaccine-Elicited Antibody Responses to Influenza H3N2 Subclade K. https://doi.org/10.64898/2026.02.02.26345378.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.02.26345378 (via https://www.medrxiv.org/content/10.64898/2026.02.02.26345378)
Influenza H3N2 subclade K (J.2.4.1) is a genetic branch of H3N2 with 11 mutations in hemagglutinin and currently represents the dominant circulating influenza strain. We evaluated antibody responses to ...

Adria Wilson, etc.,al. [preprint]Seasonal vaccine-induced immunity shows preserved cross-reactivity to H3N2 subclade K in adults. https://doi.org/10.64898/2026.02.18.26346502.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.18.26346502 (via https://www.medrxiv.org/content/10.64898/2026.02.18.26346502)
Influenza A subclade K viruses caused high infection rates in the 2025/2026 Northern Hemisphere season, raising concerns about antigenic drift and reduced vaccine effectiveness. We measured antibody responses ...

Jiaojiao Liu, etc.,al. [preprint]Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine. https://doi.org/10.64898/2026.02.20.26346746.  Abstract  
submitted by kickingbird at Feb, 23, 2026 from https://doi.org/10.64898/2026.02.20.26346746 (via https://www.medrxiv.org/content/10.64898/2026.02.20.26346746)
An H3N2 variant, named subclade K, continues to circulate widely during the 2025-2026 influenza season. This virus possesses a hemagglutinin (HA) protein that has eleven substitutions relative to the HA ...

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