Chiba S, Kiso M, Yamada S, Someya K, Onodera Y, Ya. An mRNA vaccine candidate encoding H5HA clade 2.3.4.4b protects mice from clade 2.3.2.1a virus infection. NPJ Vaccines. 2024 Oct 14;9(1):189. Abstract
submitted by kickingbird at Oct, 15, 2024 from NPJ Vaccines. 2024 Oct 14;9(1):189 (via https://www.nature.com/articles/s41541-024-00988-9)
Highly pathogenic avian influenza (HPAI) H5 viruses from different clades have been circulating globally, threatening wild/domestic birds and mammals. Given frequent spillovers and high mortality among ... Sobhy NM, Mu?oz AQ, Youssef CRB, Goyal SM. Comparative Inactivation of Three Different Subtypes of Avian Influenza Virus by Ozonized Water. Avian Dis. 2024 Sep;68(3):225-230.. Abstract
submitted by kickingbird at Oct, 15, 2024 from Avian Dis. 2024 Sep;68(3):225-230. (via https://bioone.org/journals/avian-diseases/volume-68/issue-3)
Avian influenza virus (AIV) causes frequent outbreaks in poultry with high morbidity and mortality. The virus can survive on different fomites, resulting in indirect transmission to susceptible hosts. ... Hsueh CS, Fasina O, Pi?eyro P, Ruden R, El-Gazzar. Histopathologic Features and Viral Antigen Distribution of H5N1 Highly Pathogenic Avian Influenza Virus Clade 2.3.4.4b from the 2022-2023 Outbreak in Iowa Wild Birds. Avian Dis. 2024 Sep;68(3):272-281. Abstract
submitted by kickingbird at Oct, 15, 2024 from Avian Dis. 2024 Sep;68(3):272-281 (via https://bioone.org/journals/avian-diseases/volume-68/issue-3)
In 2022, a new epornitic of H5N1 highly pathogenic avian influenza (HPAI) virus clade 2.3.4.4b emerged in U.S. domestic poultry with high prevalence in wild bird populations. We describe pathological findings ... WHO. Influenza at the human-animal interface summary and assessment, 27 September 2024. WHO. Abstract
submitted by kickingbird at Oct, 15, 2024 from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 20 July to 27 September 2024, the detection of influenza A(H5) virus in one human, influenza A(H5N1) in eight humans, influenza A(H9N2) virus in two humans, influenza A(H1N1) variant ((H1N1)v) virus ... Vatzia E, Paudyal B, Dema B, Carr BV, Sedaghat-Ros. Aerosol immunization with influenza matrix, nucleoprotein, or both prevents lung disease in pig. NPJ Vaccines. 2024 Oct 13;9(1):188. Abstract
submitted by kickingbird at Oct, 14, 2024 from NPJ Vaccines. 2024 Oct 13;9(1):188 (via https://www.nature.com/articles/s41541-024-00989-8)
Current influenza vaccines are strain-specific and require frequent updates to combat new strains, making a broadly protective influenza vaccine (BPIV) highly desirable. A promising strategy is to induce ... APHIS. Highly Pathogenic Avian Influenza H5N1 Genotype B3.13 in Dairy Cattle: National Epidemiologic Brief. USDA. Abstract
submitted by kickingbird at Oct, 14, 2024 from USDA (via https://www.aphis.usda.gov/sites/default/files/highly-pathog)
On March 25, 2024, USDA announced unpasteurized, clinical samples of milk from sick cattle collected from two dairy farms in Kansas and one in Texas, as well as an oropharyngeal swab from another dairy ... Qin Li, etc.,al. Thin-film freeze-drying of an influenza virus hemagglutinin mRNA vaccine in unilamellar lipid nanoparticles with blebs. Journal of Controlled Release. Abstract
submitted by kickingbird at Oct, 13, 2024 from Journal of Controlled Release (via https://www.sciencedirect.com/science/article/abs/pii/S01683)
Messenger RNA (mRNA) vaccines have revolutionized the fight against infectious diseases and are poised to transform other therapeutic areas. Lipid nanoparticles (LNP) represent the most successful delivery ... Marcus Tong Zhen Wei, etc.,al. High glycaemic variability is associated with a reduced T cell cytokine response to influenza A virus. iScience. Abstract
submitted by kickingbird at Oct, 13, 2024 from iScience (via https://www.sciencedirect.com/science/article/pii/S258900422)
Diabetes mellitus significantly increases the risk of severe respiratory virus disease like influenza and COVID-19. Early evidence suggests that this susceptibility to respiratory viral disease is driven ... Tian Y, Lu X, Xiao D, Zhou C.. Long-Lasting Chemiluminescence Based on Functionalized Multicolor Protein Capsules for Multiple Visualization Detection of Avian Influenza Virus Biomarkers. Anal Chem. 2024 Oct 11. Abstract
submitted by kickingbird at Oct, 12, 2024 from Anal Chem. 2024 Oct 11 (via https://pubs.acs.org/doi/10.1021/acs.analchem.4c04248)
Long-lasting chemiluminescence (CL) emissions are necessary for improving the detection accuracy and expanding the application scope. Here, we have synthesized three oil-in-water (O/W) multicolor protein ... Joseph D. Trimarco, etc.,al. Fluorescent and bioluminescent bovine H5N1 influenza viruses for evaluation of antiviral interventions. Virology，10 Oct 2024. Abstract
submitted by kickingbird at Oct, 12, 2024 from Virology，10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01385-24)
In early 2024, a clade 2.3.4.4b high pathogenic H5N1 avian influenza virus was detected in dairy cows and humans in the United States. Since then, it has spread to herds in at least 13 states and caused ... María Ríos Carrasco, Andrea Gr?ne, Judith M. A. v. The mammary glands of cows abundantly display receptors for circulating avian H5 viruses. Virology， 10 Oct 2024. Abstract
submitted by kickingbird at Oct, 11, 2024 from Virology， 10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01052-24)
Influenza A viruses (IAVs) from the H5N1 2.3.4.4b clade are circulating in dairy farms in the USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive mammalian species were hunters ... Jarek Juraszek, etc.,al. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH-switches. PNAS Nexus. Abstract
submitted by kickingbird at Oct, 11, 2024 from PNAS Nexus (via https://academic.oup.com/pnasnexus/advance-article/doi/10.10)
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ... Owuor DC, Ngoi JM, Nyasimi FM, Murunga N, Nyiro JU. Local patterns of spread of influenza A H3N2 virus in coastal Kenya over a 1-year period revealed through virus sequence data. Sci Rep. 2024 Oct 8;14(1):23426. Abstract
submitted by kickingbird at Oct, 11, 2024 from Sci Rep. 2024 Oct 8;14(1):23426 (via https://www.nature.com/articles/s41598-024-74218-6)
The patterns of spread of influenza A viruses in local populations in tropical and sub-tropical regions are unclear due to sparsity of representative spatiotemporal sequence data. We sequenced and analyzed ... Zhang K, Cagatay T, Xie D, Angelos AE, Cornelius S. Cellular NS1-BP Protein Interacts with the mRNA Export Receptor NXF1 to Mediate Nuclear Export of Influenza Virus M mRNAs. J Biol Chem. 2024 Oct 7:107871. Abstract
submitted by kickingbird at Oct, 11, 2024 from J Biol Chem. 2024 Oct 7:107871 (via https://www.jbc.org/article/S0021-9258(24)02373-1/fulltext)
Influenza A viruses have eight genomic RNAs that are transcribed in the host cell nucleus. Two of the viral mRNAs undergo alternative splicing. The M1 mRNA encodes the matrix protein 1 (M1) and is also ... Schaub A, Luo B, David SC, Glas I, Klein LK, Costa. Salt Supersaturation as an Accelerator of Influenza A Virus Inactivation in 1 μL Droplets. Environ Sci Technol. 2024 Oct 11. Abstract
submitted by kickingbird at Oct, 11, 2024 from Environ Sci Technol. 2024 Oct 11 (via https://pubs.acs.org/doi/10.1021/acs.est.4c04734)
Influenza A virus (IAV) spreads through exhaled aerosol particles and larger droplets. Estimating the stability of IAV is challenging and depends on factors such as the respiratory matrix and drying kinetics. ... Musa E, Nia ZM, Bragazzi NL, Leung D, Lee N, Kong. Avian Influenza: Lessons from Past Outbreaks and an Inventory of Data Sources, Mathematical and AI Models, and Early Warning Systems for Forecasting and Hotspot Detection to Tackle Ongoing Outbreaks. Healthcare. 2024; 12(19):1959. Abstract
submitted by kickingbird at Oct, 11, 2024 from Healthcare. 2024; 12(19):1959 (via https://www.mdpi.com/2227-9032/12/19/1959)
Background/Objectives: The ongoing avian influenza (H5N1) outbreak, one of the most widespread and persistent in recent history, has significantly impacted public health and the poultry and dairy cattle ... Andrew J Lee, etc.,al. Wastewater monitoring of human and avian influenza A viruses in Northern Ireland: a genomic surveillance study. The Lancet Microbe. Abstract
submitted by kickingbird at Oct, 11, 2024 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
BackgroundInfluenza A viruses (IAVs) are significant pathogens of humans and other animals. Although endemic in humans and birds, novel IAV strains can emerge, jump species, and cause epidemics, like the ... Reina Yamaji, etc.,al. Pandemic risk characterisation of zoonotic influenza A viruses using the Tool for Influenza Pandemic Risk Assessment (TIPRA). The Lancet Microbe. Abstract
submitted by kickingbird at Oct, 11, 2024 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
A systematic risk assessment approach is essential for evaluating the relative risk of influenza A viruses (IAVs) with pandemic potential. To achieve this, the Tool for Influenza Pandemic Risk Assessment ... Li Y, Sun Z, Liu X, Wei S, Zhang Y, Fuxiang Y, Qia. Highly Pathogenic Avian Influenza A(H5N1) Virus infection in dairy cattle:threat of bird flu has expanded to open-air farmed livestock. J Infect. 2024 Oct 7:106311. Abstract
submitted by kickingbird at Oct, 11, 2024 from J Infect. 2024 Oct 7:106311 (via https://www.journalofinfection.com/article/S0163-4453(24)002)
We read with interest the recent letter by Cai and colleagues who commented on recent cross-species activity of H5N1 Influenza virus and urged continuing surveillance of avian influenza. In March, the ... Kessler S, Stegen P, Zhan S, Schwemmle M, Reuther. Jamaican fruit bats mount a stable and highly neutralizing antibody response after bat influenza virus infection. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e241. Abstract
submitted by kickingbird at Oct, 11, 2024 from Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e241 (via https://pnas.org/doi/10.1073/pnas.2413619121)
Antibodies are an essential component of the antiviral response in many species, but to date, there is no compelling evidence that bats are capable of eliciting a robust humoral immunity, including neutralizing ... 8125 items, 20/Page, Page[8/407][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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