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2024-11-23 8:57:53
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Kristensen C, Larsen LE, Trebbien R, Jensen HE. The avian influenza A virus receptor SA-α2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses. Virus Res. 2023 Dec 22:199304.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Virus Res. 2023 Dec 22:199304 (via https://pubmed.ncbi.nlm.nih.gov/38142890/)
Influenza A viruses (IAVs) originate from wild birds but have on several occasions jumped host barriers and are now also circulating in humans and mammals. The IAV host receptors (glycans with galactose ...

Lean FZX, Falchieri M, Furman N, Tyler G, Robinson. Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022. Vet Pathol. 2023 Dec 23:3009858231217224.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Vet Pathol. 2023 Dec 23:3009858231217224 (via https://journals.sagepub.com/doi/10.1177/03009858231217224)
The reemergence of the highly pathogenic avian influenza virus (HPAIV) subtype H5N1 in the United Kingdom in 2021-2022 has caused unprecedented epizootic events in wild birds and poultry. During the summer ...

Hickerson BT, Huang BK, Petrovskaya SN, Ilyushina. Genomic Analysis of Influenza A and B Viruses Carrying Baloxavir Resistance-Associated Substitutions Serially Passaged in Human Epithelial Cells. Viruses. 2023 Dec 16;15(12):2446.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Dec 16;15(12):2446 (via https://www.mdpi.com/1999-4915/15/12/2446)
Baloxavir marboxil (baloxavir) is an FDA-approved inhibitor of the influenza virus polymerase acidic (PA) protein. Here, we used next-generation sequencing to compare the genomic mutational profiles of ...

Bidoudan Y, Mouahid M, Fassi Fihri O, Bollo E, Arb. First Report of Low Pathogenic Avian Influenza Subtype H9N2 in African Houbara Bustards ( Chlamydotis undulata undulata) and Gamebirds in Morocco: Clinico-Pathological Findings, Molecular Characteriza. Viruses. 2023 Dec 1;15(12):2374.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Dec 1;15(12):2374 (via https://www.mdpi.com/1999-4915/15/12/2374)
We report in this paper the first detection of low pathogenic avian influenza (LPAI) subtype H9N2 in houbara bustards and in gamebirds in Morocco. Starting in 2019, an increase in mortality rates related ...

Wu R, Zeng X, Wu M, Xie L, Xu G, Mao Y, Wang Z, Ch. The Mobility of Eurasian Avian-like M2 Is Determined by Residue E79 Which Is Essential for Pathogenicity of 2009 Pandemic H1N1 Influenza Virus in Mice. Viruses. 2023 Nov 30;15(12):2365.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 30;15(12):2365 (via https://www.mdpi.com/1999-4915/15/12/2365)
In 2009, a novel H1N1 influenza virus caused the first influenza pandemic of the 21st century. Studies have shown that the influenza M gene played important roles in the pathogenicity and transmissibility ...

Arbani O, Ducatez MF, Mahmoudi S, Salamat F, Khayi. Low Pathogenic Avian Influenza H9N2 Viruses in Morocco: Antigenic and Molecular Evolution from 2021 to 2023. Viruses. 2023 Nov 30;15(12):2355.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 30;15(12):2355 (via https://www.mdpi.com/1999-4915/15/12/2355)
Avian influenza viruses pose significant threats to both the poultry industry and public health worldwide. Among them, the H9N2 subtype has gained substantial attention due to its high prevalence, especially ...

Sakuma S, Tanikawa T, Tsunekuni R, Mine J, Kumagai. Experimental Infection of Chickens with H5N8 High Pathogenicity Avian Influenza Viruses Isolated in Japan in the Winter of 2020-2021. Viruses. 2023 Nov 23;15(12):2293.  Abstract  
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 23;15(12):2293 (via https://www.mdpi.com/1999-4915/15/12/2293)
During the winter of 2020-2021, numerous outbreaks of high pathogenicity avian influenza (HPAI) were caused by viruses of the subtype H5N8 in poultry over a wide region in Japan. The virus can be divided ...

Montgomery MP, Morris SE, Rolfes MA, Kittikraisak. The role of asymptomatic infections in influenza transmission: what do we really know. Lancet Infect Dis. 2023 Dec 18:S1473-3099(23)00619.  Abstract  
submitted by kickingbird at Dec, 22, 2023 from Lancet Infect Dis. 2023 Dec 18:S1473-3099(23)00619 (via https://www.thelancet.com/journals/laninf/article/PIIS1473-3)
Before the COVID-19 pandemic, the role of asymptomatic influenza virus infections in influenza transmission was uncertain. However, the importance of asymptomatic infection with SARS-CoV-2 for onward transmission ...

Buckrell S, Ben Moussa M, Bui T, Rahal A, Schmidt. National Influenza Annual Report, Canada, 2021-2022: A brief, late influenza epidemic. Can Commun Dis Rep. 2022 Oct 1;48(10):473-483.  Abstract  
submitted by kickingbird at Dec, 21, 2023 from Can Commun Dis Rep. 2022 Oct 1;48(10):473-483 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10730107/)
Canadian seasonal influenza circulation had been suppressed since the beginning of the coronavirus disease 2019 (COVID-19) pandemic. This suppression was reported globally and generated concern that the ...

Siegers JY, Wille M, Yann S, Tok S, Sin S, Chea S,. Detection and Phylogenetic Analysis of Contemporary H14N2 Avian Influenza A Virus in Domestic Ducks in Southeast Asia (Cambodia). Emerg Microbes Infect. 2023 Dec 19:2297552.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Emerg Microbes Infect. 2023 Dec 19:2297552 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Avian influenza virus (AIV) in Asia is a complex system with numerous subtypes and a highly porous wild birds-poultry interface. Certain AIV subtypes, such as H14, are underrepresented in current surveillance ...

Hubbard LE, Givens CE, Stelzer EA, Killian ML, Kol. Environmental Surveillance and Detection of Infectious Highly Pathogenic Avian Influenza Virus in Iowa Wetlands. Environ Sci Technol Lett . 2023 Nov 15;10(12):1181.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Environ Sci Technol Lett . 2023 Nov 15;10(12):1181 (via https://pubs.acs.org/doi/10.1021/acs.estlett.3c00668)
Avian influenza viruses (AIVs) infect both wild birds and domestic poultry, resulting in economically costly outbreaks that have the potential to impact public health. Currently, a knowledge gap exists ...

Szablewski CM, McBride DS, Trock SC, Habing GG, Ho. Evolution of influenza A viruses in exhibition swine and transmission to humans, 2013-2015. Zoonoses Public Health. 2023 Dec 18.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Zoonoses Public Health. 2023 Dec 18 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13104)
Aims: Swine are a mixing vessel for the emergence of novel reassortant influenza A viruses (IAV). Interspecies transmission of swine-origin IAV poses a public health and pandemic risk. In the United States, ...

Sun X, Belser JA, Pulit-Penaloza JA, Brock N, Kier. A naturally occurring HA-stabilizing amino acid (HA1-Y17) in an A(H9N2) low-pathogenic influenza virus contributes to airborne transmission. mBio. 2023 Dec 19:e0295723.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from mBio. 2023 Dec 19:e0295723 (via https://journals.asm.org/doi/10.1128/mbio.02957-23)
Despite the accumulation of evidence showing that airborne transmissible influenza A virus (IAV) typically has a lower pH threshold for hemagglutinin (HA) fusion activation, the underlying mechanism for ...

Wen F, Wang C, Guo J, Yu H, Yuan S, Li Y, Li Z, Hu. Development and application of a triplex real-time PCR assay for the detection of H3, H4, and H5 subtypes of avian influenza virus. Poult Sci. 2023 Nov 30;103(2):103333.  Abstract  
submitted by kickingbird at Dec, 20, 2023 from Poult Sci. 2023 Nov 30;103(2):103333 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) poses a significant threat to the poultry industry and public health. Among the diverse AIV subtypes, H3, H4, and H5 are frequently detected in waterfowl and live poultry markets ...

Hu J, Zeng Z, Chen X, Zhang M, Hu Z, Gu M, Wang X,. Phosphorylation of PB2 at serine 181 restricts viral replication and virulence of the highly pathogenic H5N1 avian influenza virus in mice. Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4.  Abstract  
submitted by kickingbird at Dec, 18, 2023 from Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) still poses a pandemic threat to public health, causing a high mortality rate annually and during pandemic years. Posttranslational modification of the viral protein plays a substantial ...

Chenavier F, Estrozi LF, Teulon JM, Zarkadas E, Fr. Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv. 2023 Dec 15;9(50):eadj9974.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Sci Adv. 2023 Dec 15;9(50):eadj9974 (via https://www.science.org/doi/10.1126/sciadv.adj9974)
Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. Although ...

European Food Safety Authority (EFSA); Aznar I, Ko. Annual report on surveillance for avian influenza in poultry and wild birds in Member States of the European Union in 2022. EFSA J. 2023 Dec 14;21(12):e8480.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from EFSA J. 2023 Dec 14;21(12):e8480 (via https://efsa.onlinelibrary.wiley.com/doi/full/10.2903/j.efsa)
All European Union (EU) Member States (MSs) are required to implement surveillance for avian influenza (AI) in poultry and wild birds and (i) to notify the outbreaks, when relevant and (ii) to report the ...

Kapczynski DR, Chrzastek K, Shanmugasundaram R, Zs. Efficacy of recombinant H5 vaccines delivered in ovo or day of age in commercial broilers against the 2015 U.S. H5N2 clade 2.3.4.4c highly pathogenic avian Influenza virus. Virol J. 2023 Dec 15;20(1):298.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Virol J. 2023 Dec 15;20(1):298 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Avian influenza is a highly contagious, agriculturally relevant disease that can severely affect the poultry industry and food supply. Eurasian-origin H5Nx highly pathogenic avian influenza ...

Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saund. Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses. Cell Rep. 2023 Dec 13;42(12):113553.  Abstract  
submitted by kickingbird at Dec, 17, 2023 from Cell Rep. 2023 Dec 13;42(12):113553 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(23)015)
The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques ...

Li Y, Shang J, Luo J, Zhang F, Meng G, Feng Y, Jia. Rapid detection of H5 subtype avian influenza virus using CRISPR Cas13a based-lateral flow dipstick. Front Microbiol. 2023 Nov 29;14:1283210.  Abstract  
submitted by kickingbird at Dec, 15, 2023 from Front Microbiol. 2023 Nov 29;14:1283210 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1283)
Due to its high mortality rate, highly pathogenic avian influenza (HPAI), a notifiable animal illness designated by the World Organisation for Animal Health (WOAH), has caused enormous financial losses ...

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