Hu J, Li J, You W, Liu L, Chen H. Disruption of the local vRNA structure at the end of HA encoding region interferes with the selective packaging of influenza A virus genome. Biochem Biophys Res Commun. 2025 Dec 3;795:153082. Abstract
submitted by kickingbird at 11 days ago from Biochem Biophys Res Commun. 2025 Dec 3;795:153082 (via https://www.sciencedirect.com/science/article/abs/pii/S00062)
Influenza A virus (IAV) selectively packages eight distinct viral RNA (vRNA) segments into progeny virions through segment-specific packaging signals located in the noncoding regions and their adjacent ... Jin Y, Cui H, Jiang L, et al. From Surfaces to Spillover: Environmental Persistence and Indirect Transmission of Influenza A(H3N8) Virus. Microorganisms. 2025; 13(12):2782. Abstract
submitted by kickingbird at 12 days ago from Microorganisms. 2025; 13(12):2782 (via https://www.mdpi.com/2076-2607/13/12/2782)
Avian influenza viruses (AIVs) pose a significant zoonotic threat, with the emerging H3N8 subtype raising increasing concern due to sporadic human infections. Current strategies for risk assessment of ... David C. Brice, etc.,al. Immunogenicity and efficacy of commercial poultry avian influenza vaccines against HPAI A(H5N1) clade 2.3.4.4b viruses in Mexico. Virology. Abstract
submitted by kickingbird at 12 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The high-pathogenicity avian influenza A (H5N1) viruses of clade 2.3.4.4 b have been detected in domestic poultry and wild birds in Mexico. Vaccination with H5 vaccines has been implemented as a complementary ... Jingjing Zhang, etc.,al. Genomic and structural characterization of a reassortant H9N2 avian influenza virus from a human case. International Journal of Infectious Diseases. Abstract
submitted by kickingbird at 12 days ago from International Journal of Infectious Diseases (via https://www.sciencedirect.com/science/article/pii/S120197122)
BackgroundThe H9N2 subtype of avian influenza virus (AIV) is widely distributed in poultry and occasionally infects humans, posing a potential public health risk. While most infections are mild, severe ... Liedes, O., Reinholm, A., Ekstr?m, N. et al. Influenza A(H5N8) vaccine induces humoral and cell-mediated immunity against highly pathogenic avian influenza clade 2.3.4.4b A(H5N1) viruses in at-risk individuals. Nat Microbiol (2025). Abstract
submitted by kickingbird at 13 days ago from Nat Microbiol (2025) (via https://www.nature.com/articles/s41564-025-02183-5)
Finland faced an outbreak of highly pathogenic clade 2.3.4.4b A(H5N1) avian influenza in 2023, which spread from wild birds to fur farms. Vaccinations of at-risk individuals began in June 2024 using the ... Kephart, S.M., Awatramani, K.F., Saunders, M.I. et. Host switching mutations in H5N1 influenza hemagglutinin suppress site-specific activation dynamics. Nat Commun (2025). Abstract
submitted by kickingbird at 13 days ago from Nat Commun (2025) (via https://link.springer.com/article/10.1038/s41467-025-66926-y)
Increase in human H5N1 spillover infections resulting from dissemination of highly pathogenic avian influenza (HPAI) virus into bird and mammal populations raises concerns about HPAI gaining human transmissibility. ... Saubi N, Andrés C, Prats-Méndez I, González-Sánche. Expansion of influenza A(H1N1)pdm09 NA:S247N viruses with reduced susceptibility to oseltamivir, Catalonia, Spain, and in Europe, July to October 2025. Euro Surveill. 2025 Dec;30(48). Abstract
submitted by kickingbird at 14 days ago from Euro Surveill. 2025 Dec;30(48) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Between July and October 2025, among the total 117 influenza A(H1N1)pdm09 strains characterised in Catalonia, 20% to 100% per week were carrying the NA:S247N substitution. The mutation, conferring reduced ... Harrell TL, Alvarez-Narvaez S, Porto-Fett ACS, Vin. Inactivation of avian influenza virus in yogurt made from raw milk. Food Microbiol. 2026 Apr;135:104975. Abstract
submitted by kickingbird at 14 days ago from Food Microbiol. 2026 Apr;135:104975 (via https://www.sciencedirect.com/science/article/pii/S074000202)
In March 2024, highly pathogenic avian influenza (HPAIV) H5N1 was first detected in U.S. dairy cattle and has since spread to herds across at least 17 states. Infected cows typically present with mastitis, ... Matyszewska D, Kapu?cińska M, Fontaine P. Elucidating the nature of the interactions of oseltamivir with the 2D model of influenza A virus lipid envelope. Colloids Surf B Biointerfaces. 2025 Nov 29;259:115. Abstract
submitted by kickingbird at 14 days ago from Colloids Surf B Biointerfaces. 2025 Nov 29;259:115 (via https://www.sciencedirect.com/science/article/pii/S092777652)
This study investigates the molecular interactions of the antiviral agent oseltamivir phosphate (OSL) with a two-dimensional (2D) Langmuir monolayer model of the influenza A (AH1N1) virus lipid envelope. ... Reeves C, Miura SST, Chappell AR, Banaag A, Coles. Trends in influenza vaccination uptake in a universally insured population in the united states, 2017-2023. Vaccine. 2025 Dec 3;71:128052. Abstract
submitted by kickingbird at 14 days ago from Vaccine. 2025 Dec 3;71:128052 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
Background: Annual vaccination against seasonal influenza is recommended for all persons ages ≥6 months in the U.S., as it is effective in reducing influenza-related illness and death. However, data show ... Qian Zhang, etc.,al. Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza. J Exp Med 2 March 2026; 223 (3): e20251962. Abstract
submitted by kickingbird at 14 days ago from J Exp Med 2 March 2026; 223 (3): e20251962 (via https://rupress.org/jem/article/223/3/e20251962/278557/Autoa)
Avian influenza A virus (IAV) H5N1 is an emerging threat of human pandemic. We describe a 71-year-old man who died of H5N1 pneumonia in Louisiana and whose blood contained autoantibodies neutralizing type ... An Y, Ding X, Tian Y, Zhang M, Ma Y, Wu X, Cai M,. High-throughput pseudovirus neutralisation maps the antigenic landscape of influenza A/H1N1 viruses. EBioMedicine. 2025 Dec 2;122:106047. Abstract
submitted by kickingbird at 15 days ago from EBioMedicine. 2025 Dec 2;122:106047 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The continuous mutations in the haemagglutinin gene in A/H1N1 influenza viruses drives antigenic drift, necessitating frequent vaccine updates. Pseudovirus systems, with their flexible HA protein ... Huddleston J, Bedford T. Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2. Elife. 2025 Dec 4;14:RP104282. Abstract
submitted by kickingbird at 15 days ago from Elife. 2025 Dec 4;14:RP104282 (via https://elifesciences.org/articles/104282)
Evolutionary forecasting models inform seasonal influenza vaccine design by predicting which current genetic variants will dominate in the influenza season 12 months later. Forecasting models depend on ... Frutos AM, Moon S, Binder AM, Cool AJ, Iyawe K, Th. Evaluation of a Novel Data Source for National Influenza Surveillance: Influenza Hospitalization Data in the National Healthcare Safety Network, United States, September 2021-April 2024. Am J Public Health. 2025 Dec 4:e1-e5. Abstract
submitted by kickingbird at 15 days ago from Am J Public Health. 2025 Dec 4:e1-e5 (via https://ajph.aphapublications.org/doi/full/10.2105/AJPH.2025)
Objectives. To evaluate the completeness and utility of influenza hospital data reported to the Centers for Disease Control and Prevention's National Healthcare Safety Network (NHSN) from September 2021 ... ECDC. Scenarios for pre-pandemic zoonotic influenza preparedness and response. ECDC. Abstract
submitted by kickingbird at 15 days ago from ECDC (via https://www.ecdc.europa.eu/en/publications-data/scenarios-pr)
We have defined 14 scenarios based on specific epidemiological and virological factors, including animal origin, characteristics of human cases (number and exposure context), severity signals, that are ... Guan L, etc., al. Stability of Avian Influenza A(H5N1) Virus in Milk from Infected Cows and Virus-Spiked Milk. N Engl J Med . 2025 Dec 4;393(22):2271-2273. Abstract
submitted by kickingbird at 16 days ago from N Engl J Med . 2025 Dec 4;393(22):2271-2273 (via https://www.nejm.org/doi/10.1056/NEJMc2502494)
In March 2024, public health agencies in the United States reported highly pathogenic avian influenza (HPAI) virus of subtype A(H5N1) in dairy cattle, with virus detected in milk samples from symptomatic ... Kerry Goldin, Meaghan Flagg, Tessa Lutterman, etc. Contemporary highly pathogenic avian influenza (H5N1) viruses retain neurotropism in human cerebral organoids. Open Forum Infectious Diseases, ofaf730. Abstract
submitted by kickingbird at Dec, 3, 2025 from Open Forum Infectious Diseases, ofaf730 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
BackgroundClade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 viruses are widely circulating in North America with unprecedented transmission into novel host species. A high incidence of neurologic ... Jaume A. Badia-Boher, Michael Schaub, etc.,al. Evaluating the demographic impacts of the highly pathogenic avian influenza panzootic. Journal of Applied Ecology. Abstract
submitted by kickingbird at Dec, 3, 2025 from Journal of Applied Ecology (via https://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365)
The spread of a new highly pathogenic avian influenza virus (HPAIV-H5N1) has, since 2021, triggered one of the most severe wildlife panzootic ever reported, with suspected population crashes in hundreds ... Maddock KJ. 0. A raw deal: the intersection of the immunocompromised cat, influenza, and a lapse of infection prevention and control measures. ASM Case Rep 0:e00180-25. Abstract
submitted by kickingbird at Dec, 3, 2025 from ASM Case Rep 0:e00180-25 (via https://journals.asm.org/doi/10.1128/asmcr.00180-25)
The case report by Chen et al. (ASM Case Rep 1:e00134-25, 2025, https://doi.org/10.1128/asmcr.00134-25) importantly describes nosocomial transmission of highly pathogenic avian influenza (HPAI) in an immunocompromised ... Zhang J, Cao R, Wang Y, Sun Y, Ji X, et al. Influenza virus infection reprograms cholesterol biosynthesis to facilitate virus replication by the TAK1-RORγ axis. PLOS Pathogens 21(10): e1013646. Abstract
submitted by kickingbird at Dec, 3, 2025 from PLOS Pathogens 21(10): e1013646 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Infection and replication of enveloped viruses require host cells to supply substantial amounts of cellular cholesterol for processes such as binding, entry, trafficking, assembly, and budding. However, ... 9563 items, 20/Page, Page[4/479][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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