WHO. Options for the use of human H5N1 influenza vaccines and the WHO H5N1 vaccine stockpile. WHO. Full Text
submitted by kickingbird at May, 28, 2008 from WHO (via http://www.who.int/csr/resources/publications/WHO_HSE_EPR_GI)
WHO/HSE/EPR/GIP/2008.1- English - PDF [pdf 159kb]
Contents
Executive summary 1. Characteristics of candidate human H5N1 influenza vaccines2. Options for using human H5N1 influenza vaccines3. Options ... Jessica A. Belser, etc.,al. Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility. pnas.0801259105. Abstract
submitted by kickingbird at May, 28, 2008 from pnas.0801259105 (via http://www.pnas.org/cgi/content/abstract/105/21/7558)
Avian H7 influenza viruses from both the Eurasian and North American lineage have caused outbreaks in poultry since 2002, with confirmed human infection occurring during outbreaks in The Netherlands, British ... Song L, Nakaar V, Kavita U, Price A, Huleatt J, Ta. Efficacious recombinant influenza vaccines produced by high yield bacterial expression: a solution to global pandemic and seasonal needs. PLoS ONE. 2008 May 21;3(5):e2257. Abstract
submitted by kickingbird at May, 27, 2008 from PLoS ONE. 2008 May 21;3(5):e2257 (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
It is known that physical linkage of TLR ligands and vaccine antigens significantly enhances the immunopotency of the linked antigens. We have used this approach to generate novel influenza vaccines that ... Uetani K, Hiroi M, Meguro T, Ogawa H, Kamisako T,. Influenza A virus abrogates IFN-gamma response in respiratory epithelial cells by disruption of the Jak/Stat pathway. Eur J Immunol. 2008 Jun;38(6):1559-1573.. Abstract
submitted by kickingbird at May, 27, 2008 from Eur J Immunol. 2008 Jun;38(6):1559-1573. (via http://www.ncbi.nlm.nih.gov/pubmed/18493979?ordinalpos=8&ito)
The innate immunity to viral infections induces a potent antiviral response mediated by interferons (IFN). Although IFN-gamma is detected during the acute stages of illness in the upper respiratory tract ... Chen LM, Davis CT, Zhou H, Cox NJ, Donis RO.. Genetic Compatibility and Virulence of Reassortants Derived from Contemporary Avian H5N1 and Human H3N2 Influenza A Viruses. PLoS Pathog. 2008 May 23;4(5):e1000072. Abstract
submitted by kickingbird at May, 27, 2008 from PLoS Pathog. 2008 May 23;4(5):e1000072 (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
The segmented structure of the influenza virus genome plays a pivotal role in its adaptation to new hosts and the emergence of pandemics. Despite concerns about the pandemic threat posed by highly pathogenic ... Boltz DA, Rehg JE, McClaren J, Webster RG, Govorko. Oseltamivir Prophylactic Regimens Prevent H5N1 Influenza Morbidity and Mortality in a Ferret Model.. J Infect Dis. 2008 May 1;197(9):1315-1323.. Abstract
submitted by kickingbird at May, 6, 2008 from J Infect Dis. 2008 May 1;197(9):1315-1323. (via http://www.ncbi.nlm.nih.gov/pubmed/18422444)
Background. Current oseltamivir prophylactic regimens may not be as effective against highly pathogenic H5N1 influenza viruses as they are against less pathogenic strains. An optimal regimen is urgently ... Svitek N, Rudd PA, Obojes K, Pillet S, von Messlin. Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction. Virology. 2008 Apr 15. Abstract
submitted by kickingbird at May, 6, 2008 from Virology. 2008 Apr 15 (via http://www.ncbi.nlm.nih.gov/pubmed/18420248)
Even though ferrets are one of the principal animal models for influenza pathogenesis, the lack of suitable immunological reagents has so far limited their use in host response studies. Using recently ... Song D, Kang B, Lee C, Jung K, Ha G, Kang D, et al. Transmission of Avian Influenza Virus (H3N2) to Dogs. Emerg Infect Dis 2008 May. Abstract
submitted by kickingbird at Apr, 27, 2008 from Emerg Infect Dis 2008 May (via http://www.cdc.gov/eid/content/14/5/741.htm?s_cid=eid741_e)
In South Korea, where avian influenza virus subtypes H3N2, H5N1, H6N1, and H9N2 circulate or have been detected, 3 genetically similar canine influenza virus (H3N2) strains of avian origin (A/canine/Korea/01/2007, ... Li W, Liu Y, Mukhtar MM, Gong R, Pan Y, Rasool ST,. Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection. PLoS ONE. 2008 Apr 16;3(4):e1985. Abstract
submitted by kickingbird at Apr, 18, 2008 from PLoS ONE. 2008 Apr 16;3(4):e1985 (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
BACKGROUND: Interleukin (IL)-32 is a recently described pro-inflammatory cytokine that has been reported to be induced by bacteria treatment in culture cells. Little is known about IL-32 production by ... Wei CJ, Xu L, Kong WP, Shi W, Canis K, Stevens J,. Comparative Efficacy of Neutralizing Antibodies Elicited by Recombinant Hemagglutinin Proteins from Avian H5N1 Influenza Virus. J Virol. 2008 Apr 16. Abstract
submitted by kickingbird at Apr, 18, 2008 from J Virol. 2008 Apr 16 (via http://www.ncbi.nlm.nih.gov/pubmed/18417563?ordinalpos=9&ito)
Although human transmission of avian H5N1 virus remains low, the prevalence of this highly pathogenic infection in avian species underscores the need for a preventive vaccine that can be made without eggs. ... Takahashi T, Murakami K, Nagakura M, Kishita H, Wa. Sulfatide Is Required for Efficient Replication of Influenza A Virus. J Virol. 2008 Apr 16. Abstract
submitted by kickingbird at Apr, 18, 2008 from J Virol. 2008 Apr 16 (via http://www.ncbi.nlm.nih.gov/pubmed/18417587?ordinalpos=8&ito)
Sulfatide is abundantly expressed in various mammalian organs, including the intestine and trachea, in which influenza A viruses (IAVs) replicate. However, the function of sulfatide in IAV infection remains ... Rambaut A, Pybus OG, Nelson MI, Viboud C, Taubenbe. The genomic and epidemiological dynamics of human influenza A virus.. Nature. 2008 Apr 16. Abstract
submitted by kickingbird at Apr, 18, 2008 from Nature. 2008 Apr 16 (via http://www.ncbi.nlm.nih.gov/pubmed/18418375?ordinalpos=3&ito)
The evolutionary interaction between influenza A virus and the human immune system, manifest as 'antigenic drift' of the viral haemagglutinin, is one of the best described patterns in molecular evolution. ... Dung Nguyen T, Vinh Nguyen T, Vijaykrishna D, Webs. Multiple Sublineages of Influenza A Virus (H5N1), Vietnam, 2005-2007. Emerg Infect Dis. 2008 Apr;14(4):632-636.. Abstract
submitted by kickingbird at Apr, 13, 2008 from Emerg Infect Dis. 2008 Apr;14(4):632-636. (via http://www.ncbi.nlm.nih.gov/pubmed/18394281?ordinalpos=35&it)
Phylogenetic analysis of influenza subtype H5N1 viruses isolated from Vietnam during 2005-2007 shows that multiple sublineages are present in Vietnam. Clade 2.3.4 viruses have replaced clade 1 viruses ... Opri?an G, Coste H, Lupulescu E, Opri?oreanu AM, S. Molecular analysis of the first avian influenza H5N1 isolates from fowl in Romania. Roum Arch Microbiol Immunol. 2006 Jul-Dec;65(3-4):. Abstract
submitted by kickingbird at Apr, 13, 2008 from Roum Arch Microbiol Immunol. 2006 Jul-Dec;65(3-4): (via http://www.ncbi.nlm.nih.gov/pubmed/18389720?ordinalpos=44&it)
Since the events of avian influenza (AI) caused by H5N1 subtype from Hong Kong (1997), the people worldwide have been confronted with new waves of epizootic influenza. In 2005 in Romania an unprecedent ... Saltyt? Benth J, Hofoss D. Modelling and prediction of weekly incidence of influenza A specimens in England and Wales. Epidemiol Infect. 2008 Apr 7;:1-9. Abstract
submitted by kickingbird at Apr, 13, 2008 from Epidemiol Infect. 2008 Apr 7;:1-9 (via http://www.ncbi.nlm.nih.gov/pubmed/18394206?ordinalpos=37&it)
SUMMARYWe propose a rather simple model, which fits well the weekly human influenza incidence data from England and Wales. A standard way to analyse seasonally varying time-series is to decompose them ... Keawcharoen J, van Riel D, van Amerongen G, Besteb. Wild Ducks as Long-Distance Vectors of Highly Pathogenic Avian Influenza Virus (H5N1). Emerg Infect Dis. 2008 Apr;14(4):600-607. Abstract
submitted by kickingbird at Apr, 13, 2008 from Emerg Infect Dis. 2008 Apr;14(4):600-607 (via http://www.ncbi.nlm.nih.gov/pubmed/18394278?ordinalpos=36&it)
Wild birds have been implicated in the expansion of highly pathogenic avian influenza virus (H5N1) outbreaks across Asia, the Middle East, Europe, and Africa (in addition to traditional transmission by ... Monne I, Joannis TM, Fusaro A, De Benedictis P, Lo. Reassortant Avian Influenza Virus (H5N1) in Poultry, Nigeria, 2007. Emerg Infect Dis. 2008 Apr;14(4):637-640.. Abstract
submitted by kickingbird at Apr, 13, 2008 from Emerg Infect Dis. 2008 Apr;14(4):637-640. (via http://www.ncbi.nlm.nih.gov/pubmed/18394282?ordinalpos=34&it)
Genetic characterization of a selection of influenza virus (H5N1) samples, circulating in 8 Nigerian states over a 39-day period in early 2007, indicates that a new reassortant strain is present in 7 of ... Holman DH, Wang D, Raja NU, Luo M, Moore KM, Worar. Multi-antigen vaccines based on complex adenovirus vectors induce protective immune responses against H5N1 avian influenza viruses. Vaccine. 2008 Mar 14. Abstract
submitted by kickingbird at Apr, 13, 2008 from Vaccine. 2008 Mar 14 (via http://www.ncbi.nlm.nih.gov/pubmed/18395306?ordinalpos=30&it)
There are legitimate concerns that the highly pathogenic H5N1 avian influenza virus could adapt for human-to-human transmission and cause a pandemic similar to the 1918 "Spanish flu" that killed 50 million ... R?mer-Oberd?rfer A, Veits J, Helferich D, Mettenle. Level of protection of chickens against highly pathogenic H5 avian influenza virus with Newcastle disease virus based live attenuated vector vaccine depends on homology of H5 sequence between vaccine. Vaccine. 2008 Mar 18. Abstract
submitted by kickingbird at Apr, 13, 2008 from Vaccine. 2008 Mar 18 (via http://www.ncbi.nlm.nih.gov/pubmed/18395947?ordinalpos=29&it)
Vaccination of poultry against avian influenza is of high priority, in particular after the dramatic spread of subtype H5N1 in Asia, Africa and Europe. Newcastle disease virus (NDV) has been developed ... Amin R, Ford-Jones E, Richardson SE, Macgregor D,. Acute Childhood Encephalitis and Encephalopathy Associated With Influenza: A Prospective 11-Year Review. Pediatr Infect Dis J. 2008 Apr 4. Abstract
submitted by kickingbird at Apr, 13, 2008 from Pediatr Infect Dis J. 2008 Apr 4 (via http://www.ncbi.nlm.nih.gov/pubmed/18398387?ordinalpos=22&it)
BACKGROUND:: Influenza virus infection has been associated with a variety of neurologic complications. The objective of this study was to evaluate prospectively the role of influenza viruses in acute childhood ... 8128 items, 20/Page, Page[331/407][|<<] [|<] [331] [332] [333] [334] [335] [336] [337] [338] [339] [340] [>|] [>>|] |
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