Eefje J. A. Schrauwen,etc.,al. The multi basic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets. 2012, doi: 10.1128/?JVI.06828-11. Abstract
submitted by kickingbird at Jan, 28, 2012 from 2012, doi: 10.1128/?JVI.06828-11 (via http://jvi.asm.org/content/early/2012/01/18/JVI.06828-11.sho)
The route by which highly pathogenic avian influenza (HPAI) H5N1 virus spreads systemically, including the central nervous system (CNS), is largely unknown in mammals. Especially the olfactory route, which ... FONTANA J, Cardone G, Heymann JB, Winkler DC, et a. Structural changes in influenza virus at low pH characterized by cryo-electron tomography. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258245)
Influenza virus enters host cells by endocytosis. The low pH of endosomes triggers conformational changes in hemagglutinin (HA) that mediate fusion of the viral and endosomal membranes. We have used cryo-electron ... KOBAYASHI Y, Suzuki Y. Evidence for N-glycan shielding of antigenic sites during evolution of human influenza A virus hemagglutinin. J Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258255)
After the emergence of influenza A viruses in the human population, the number of N-glycosylation sites (NGS) in the globular head region of hemagglutinin (HA) has increased continuously for several decades. ... KANCHANA S, Kanchana S, Chuntrakul C, Malathum K,. Pandemic (H1N1) 2009 virus infection: persistent viral shedding after Oseltamivir treatment. J Infect. 2011;63:295-9.. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Infect. 2011;63:295-9. (via http://www.ncbi.nlm.nih.gov/pubmed/21840339)
OBJECTIVES:
To study pandemic (H1N1) 2009 virological outcomes after Oseltamivir treatment in confirmed cases of pandemic (H1N1) 2009 virus infections. A hospital-based cohort study was conducted in ... BRUCE EA, Abbink TE, Wise HM, Rollason R, et al. Release of filamentous and spherical influenza A virus is not restricted by tetherin. J Gen Virol. 2012. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Gen Virol. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22258861)
The cellular protein tetherin is thought to act as a 'leash' that anchors many enveloped viruses to the plasma membrane and prevents their release. We found that replication of multiple strains of influenza ... KOERNER I, Matrosovich MN, Haller O, Staeheli P, e. Altered receptor specificity and fusion activity of the hemagglutinin contribute to high virulence of a mouse-adapted influenza A virus. J Gen Virol. 2012.. Abstract
submitted by kickingbird at Jan, 24, 2012 from J Gen Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22258863)
The viral hemagglutinin (HA) and the viral polymerase complex determine the replication fitness of a highly virulent variant of influenza A virus strain A/PR/8/34 (designated hvPR8) and its high pathogenicity ... STONER TD, Krauss S, Turner JC, Seiler P, et al. Susceptibility of avian influenza viruses of the N6 subtype to the neuraminidase inhibitor oseltamivir. Antiviral Res. 2012.. Abstract
submitted by kickingbird at Jan, 24, 2012 from Antiviral Res. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22252168)
Avian influenza viruses are a source of genetic material that can be transmitted to humans through direct introduction or reassortment. Although there is a wealth of information concerning global monitoring ... Hongxing Hu,etc.,al. A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol, published online Jan 11. Abstract
submitted by kickingbird at Jan, 21, 2012 from J Virol, published online Jan 11 (via http://jvi.asm.org/content/early/2012/01/04/JVI.06665-11.sho)
Influenza A virus infection is a persistent threat to public health worldwide, due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza ... Jeffrey Shamana, Marc Lipsitch. The El Nino–Southern Oscillation (ENSO)–pandemic Influenza connection: Coincident or causal?. Proc Natl Acad Sci, published online Jan 17. Full Text
submitted by kickingbird at Jan, 21, 2012 from Proc Natl Acad Sci, published online Jan 17 (via http://www.pnas.org/content/early/2012/01/11/1107485109.shor)
We find that the four most recent human influenza pandemics (1918, 1957, 1968, and 2009), all of which were first identified in boreal spring or summer, were preceded by La Ni?a conditions in the equatorial ... Crossley B, Hietala S, Hunt T, Benjamin G, Martine. Pandemic (H1N1) 2009 in Captive Cheetah. Emerg Infect Dis. 2012 Feb. Abstract
submitted by kickingbird at Jan, 21, 2012 from Emerg Infect Dis. 2012 Feb (via http://wwwnc.cdc.gov/eid/article/18/2/11-1245_article.htm)
We describe virus isolation, full genome sequence analysis, and clinical pathology in ferrets experimentally inoculated with pandemic (H1N1) 2009 virus recovered from a clinically ill captive cheetah that ... DeVries etc., al. Neuraminidase H275Y and hemagglutinin D222G mutations in a fatal case of 2009 pandemic influenza A (H1N1) virus infection. Influenza and Other Respiratory Viruses DOI: 10.11. Abstract
submitted by kickingbird at Jan, 21, 2012 from Influenza and Other Respiratory Viruses DOI: 10.11 (via http://onlinelibrary.wiley.com/doi/10.1111/j.1750-2659.2011.)
Oseltamivir-resistant 2009 H1N1 influenza virus infections associated with neuraminidase (NA) H275Y have been identified sporadically. Strains possessing the hemagglutinin (HA) D222G mutation have been ... LEKCHAROENSUK P, Wiriyarat W, Petcharat N, Lekchar. Cloned cDNA of A/swine/Iowa/15/1930 internal genes as a candidate backbone for reverse genetics vaccine against influenza A viruses.. Vaccine. 2012. Abstract
submitted by kickingbird at Jan, 16, 2012 from Vaccine. 2012 (via http://www.ncbi.nlm.nih.gov/pubmed/22230579)
Reverse genetics viruses for influenza vaccine production usually utilize the internal genes of the egg-adapted A/Puerto Rico/8/34 (PR8) strain. This egg-adapted strain provides high production yield in ... HU Y, Jin Y, Han D, Zhang G, et al.. Mast cell-induced lung injury in mice infected with H5N1 influenza virus. J Virol. 2012.. Abstract
submitted by kickingbird at Jan, 16, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22238293)
Although an important role for mast cells in several viral infections has been demonstrated, its role in the invasion of highly pathogenic H5N1 influenza virus is unknown. In the present study, we demonstrated ... HU H, Voss J, Zhang G, Buchy P, et al. A Human Antibody Recognizing a Conserved Epitope of H5 Hemagglutinin Broadly Neutralizes Highly Pathogenic Avian Influenza H5N1 Viruses. J Virol. 2012.. Abstract
submitted by kickingbird at Jan, 16, 2012 from J Virol. 2012. (via http://www.ncbi.nlm.nih.gov/pubmed/22238297)
Influenza A virus infection is a persistent threat to public health worldwide, due to its ability to evade immune surveillance through rapid genetic drift and shift. Current vaccines against influenza ... OHKURA T, Kikuchi Y, Kono N, Itamura S, et al. Epitope mapping of neutralizing monoclonal antibody in avian influenza A H5N1 virus hemagglutinin.. Biochem Biophys Res Commun. 2011. Abstract
submitted by kickingbird at Jan, 16, 2012 from Biochem Biophys Res Commun. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22226969)
The global spread of highly pathogenic avian influenza A H5N1 viruses raises concerns about more widespread infection in the human population. Pre-pandemic vaccine for H5N1 clade 1 influenza viruses has ... ELKIN PL, Froehling DA, Wahner-Roedler DL, Brown S. Comparison of natural language processing biosurveillance methods for identifying influenza from encounter notes. Ann Intern Med. 2012;156.. Abstract
submitted by kickingbird at Jan, 9, 2012 from Ann Intern Med. 2012;156. (via http://www.ncbi.nlm.nih.gov/pubmed/22213490)
Background: An effective national biosurveillance system expedites outbreak recognition and facilitates response coordination at the federal, state, and local levels. The BioSense system, used at the Centers ... Trevennec, K., Leger, L., Lyazrhi, F., Baudon, E.,. Transmission of pandemic influenza H1N1 (2009) in Vietnamese swine in 2009–2010. Influenza and Other Respiratory Viruses. doi: 10.1. Abstract
submitted by kickingbird at Jan, 7, 2012 from Influenza and Other Respiratory Viruses. doi: 10.1 (via http://onlinelibrary.wiley.com/doi/10.1111/j.1750-2659.2011.)
Background The pandemic of 2009 was caused by an H1N1 (H1N1pdm) virus of swine origin. This pandemic virus has repeatedly infected swine through reverse zoonosis, although the extent of such infection ... Seema S.,etc.,al. Eurasian-Origin Gene Segments Contribute to the Transmissibility, Aerosol Release, and Morphology of the 2009 Pandemic H1N1 Influenza Virus. PLoS pathogens. Full Text
submitted by kickingbird at Jan, 7, 2012 from PLoS pathogens (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
The epidemiological success of pandemic and epidemic influenza A viruses relies on the ability to transmit efficiently from person-to-person via respiratory droplets. Respiratory droplet (RD) transmission ... Susanna Esposito, Cristina Daleno, Claudia Tagliab. Antibody response of healthy children to pandemic A/H1N1/2009 influenza virus. Virology Journal 2011, 8:563 doi:10.1186/1743-422X. Abstract
submitted by kickingbird at Jan, 7, 2012 from Virology Journal 2011, 8:563 doi:10.1186/1743-422X (via http://www.virologyj.com/content/8/1/563/abstract)
Background
Little is known about the proportion of pediatric pandemic A/H1N1/2009 influenza cases who showed seroconversion, the magnitude of this seroconversion, or the factors that can affect the antibody ... CDC. Severe Influenza Among Children and Young Adults with Neurologic and Neurodevelopmental Conditions — Ohio, 2011. MMWR January 6, 2012 / 60(51);1729-1733. Abstract
submitted by kickingbird at Jan, 6, 2012 from MMWR January 6, 2012 / 60(51);1729-1733 (via http://www.cdc.gov/mmwr/preview/mmwrhtml/mm6051a1.htm?s_cid=)
Children with neurologic and neurodevelopmental conditions are at increased risk for severe outcomes from influenza, including death (1–3). In April 2011, the Ohio Department of Health and CDC investigated ... 8128 items, 20/Page, Page[312/407][|<<] [|<] [311] [312] [313] [314] [315] [316] [317] [318] [319] [320] [>|] [>>|] |
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