Gooskens J, Jonges M, Claas EC, Meijer A, van den. Morbidity and Mortality Associated With Nosocomial Transmission of Oseltamivir-Resistant Influenza A(H1N1) Virus. JAMA. 2009 Mar 2. Abstract
submitted by kickingbird at Mar, 8, 2009 from JAMA. 2009 Mar 2 (via http://www.ncbi.nlm.nih.gov/pubmed/19255111)
CONTEXT: The sudden emergence and rapid spread of oseltamivir-resistant influenza A(H1N1) viruses with neuraminidase (NA) gene H274Y amino acid substitution is the hallmark of global seasonal influenza ... Tamura D, Mitamura K, Yamazaki M, Fujino M, Nirasa. Oseltamivir-Resistant Influenza A Viruses Circulating in Japan. J Clin Microbiol. 2009 Mar 4. Abstract
submitted by kickingbird at Mar, 8, 2009 from J Clin Microbiol. 2009 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/19261802)
Surveillance studies of influenza viruses circulating in Europe and other countries in 2007-2008 have revealed rates of resistance to oseltamivir of up to 67% among H1N1 viruses. Here, we examined 202 ... Crouch E, Hartshorn K, Horlacher T, McDonald B. Recognition of Mannosylated Ligands and Influenza A Virus by Human SP-D: Contributions of an Extended Site and Residue 343. Biochemistry. 2009 Feb 27. Abstract
submitted by kickingbird at Mar, 8, 2009 from Biochemistry. 2009 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/19249874)
Surfactant protein D (SP-D) plays important roles in antiviral host defense. Although SP-D shows a preference for glucose/maltose, the protein also recognizes D-mannose and a variety of mannose-rich microbial ... Damian C. Ekiert,etc.,al. Antibody Recognition of a Highly Conserved Influenza Virus Epitope. Science DOI: 10.1126/science.1171491. Abstract
submitted by kickingbird at Mar, 1, 2009 from Science DOI: 10.1126/science.1171491 (via http://www.sciencemag.org/cgi/content/abstract/1171491)
Influenza virus presents a significant and persistent threat to public health worldwide, and current vaccines provide immunity to viral isolates similar to the vaccine strain. High-affinity antibodies ... S. Desvaux et al.. Highly Pathogenic Avian Influenza Virus (H5N1) Outbreak in Captive Wild Birds and Cats, Cambodia. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/475.htm?s_cid=eid475_e)
From December 2003 through January 2004, the Phnom Tamao Wildlife Rescue Centre, Cambodia, was affected by the highly pathogenic influenza virus (H5N1). Birds from 26 species died. Influenza virus subtype ... A. Fusaro et al.. Introduction into Nigeria of a Distinct Genotype of Avian Influenza Virus (H5N1). Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/445.htm?s_cid=eid445_e)
Genetic characterization of highly pathogenic avian influenza viruses (H5N1) isolated in July 2008 in Nigeria indicates that a distinct genotype, never before detected in Africa, reached the continent. ... W. Putthasri et al.. Capacity of Thailand to Contain an Emerging Influenza Pandemic. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/423.htm?s_cid=eid423_e)
Southeast Asia will likely be the epicenter of the next influenza pandemic. To determine whether health system resources in Thailand are sufficient to contain an emerging pandemic, we mapped health system ... A. Gordon et al.. Prevalence and Seasonality of Influenza-like Illness in Children, Nicaragua, 2005–2007. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/408.htm?s_cid=eid408_e)
Although information about seasonality and prevalence of influenza is crucial for development of effective prevention and control strategies, limited data exist on the epidemiology of influenza in tropical ... G.J.D. Smith et al. Characterization of Avian Influenza Viruses A (H5N1) from Wild Birds, Hong Kong, 2004–2008. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/402.htm?s_cid=eid402_e)
From January 2004 through June 2008, surveillance of dead wild birds in Hong Kong, People's Republic of China, periodically detected highly pathogenic avian influenza (HPAI) viruses (H5N1) in individual ... D.S. Fedson. Meeting the Challenge of Influenza Pandemic Preparedness in Developing Countries. Emerg Infect Dis. 2009 Mar. Abstract
submitted by kickingbird at Feb, 23, 2009 from Emerg Infect Dis. 2009 Mar (via http://www.cdc.gov/eid/content/15/3/365.htm?s_cid=eid365_e)
Developing countries face unique difficulties preparing for an influenza pandemic. Our current top-down approach will not provide these countries with adequate supplies of vaccines and antiviral agents. ... Laddy DJ, Yan J, Khan AS, Anderson H, Cohn A, Gree. Electroporation of Synthetic DNA Antigens Offers Protection in Non-Human Primates Challenged with Highly Pathogenic Avian Influenza. J Virol. 2009 Feb 11.. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Virol. 2009 Feb 11. (via http://www.ncbi.nlm.nih.gov/pubmed/19211745)
Avian influenza highlights the need for novel vaccination techniques that would allow for the rapid design and production of safe and effective vaccines. An ideal platform would be capable of inducing ... Karron RA, Callahan K, Luke C, Thumar B, McAuliffe. A Live Attenuated H9N2 Influenza Vaccine Is Well Tolerated and Immunogenic in Healthy Adults. J Infect Dis. 2009 Mar 1;199(5):711-716. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Infect Dis. 2009 Mar 1;199(5):711-716 (via http://www.ncbi.nlm.nih.gov/pubmed/19210163)
Development of live attenuated influenza vaccines (LAIV) against avian strains with pandemic potential is an important public-health strategy. Either 1 or 2 10(7)-TCID(50) doses of H9N2 LAIV A/chicken/Hong ... Lipatov AS, Kwon YK, Pantin-Jackwood MJ, Swayne DE. Pathogenesis of H5N1 Influenza Virus Infections in Mice and Ferret Models Differs According to Respiratory Tract or Digestive System Exposure. J Infect Dis. 2009 Mar 1;199(5):717-25.. Abstract
submitted by kickingbird at Feb, 15, 2009 from J Infect Dis. 2009 Mar 1;199(5):717-25. (via http://www.ncbi.nlm.nih.gov/pubmed/19210164)
Background. Epidemiologic, clinical, and laboratory data suggest that H5N1 influenza viruses are transmitted through and predominantly affect the respiratory system of mammals. Some data suggest digestive ... Salomon R, Webster RG.. The influenza virus enigma. Cell. 2009 Feb 6;136(3):402-10. Abstract
submitted by kickingbird at Feb, 15, 2009 from Cell. 2009 Feb 6;136(3):402-10 (via http://www.ncbi.nlm.nih.gov/pubmed/19203576)
Both seasonal and pandemic influenza continue to challenge both scientists and clinicians. Drug-resistant H1N1 influenza viruses have dominated the 2009 flu season, and the H5N1 avian influenza virus continues ... Li Qi, John C. Kash, Vivien G. Dugan, Ruixue Wang,. Role of sialic acid binding specificity of the 1918 influenza virus hemagglutinin protein in virulence and pathogenesis in mice. JVI.02596-08. Abstract
submitted by kickingbird at Feb, 13, 2009 from JVI.02596-08 (via http://jvi.asm.org/cgi/content/abstract/JVI.02596-08v1?papet)
The 1918 influenza pandemic caused over 40 million deaths and likely resulted from introduction and adaptation of a novel avian-like virus. Influenza A virus hemagglutinins are important in host-switching ... Fislová T, Gocník M, Sládková T, Durmanová V, Raj?. Multiorgan distribution of human influenza A virus strains observed in a mouse model. Arch Virol. 2009 Feb 3.. Abstract
submitted by kickingbird at Feb, 8, 2009 from Arch Virol. 2009 Feb 3. (via http://www.ncbi.nlm.nih.gov/pubmed/19189197)
Multiorgan spread and pathogenesis of influenza infection with three human influenza A viruses was studied in mice. Mouse-adapted viruses A/Dunedin/4/73(H3N2), A/Mississippi/1/85(H3N2), and A/PR/8/34(H1N1) ... Takashi Kuzuhara, Daisuke Kise, Hiroko Yoshida, Ta. Structural basis of the influenza A virus RNA polymerase PB2 RNA-binding domain containing the pathogenicity-determinant lysine 627 residue. J. Biol. Chem, 10.1074/jbc.C800224200. Abstract
submitted by kickingbird at Feb, 5, 2009 from J. Biol. Chem, 10.1074/jbc.C800224200 (via http://www.jbc.org/cgi/content/abstract/C800224200v1)
Since the influenza A virus has an RNA genome, its RNA-dependent RNA polymerase, comprising the PA, PB1 and PB2 subunits, is essential for viral transcription and replication. The binding of RNA primers/promoters ... Oleg P Zhirnov, Vladimir V Syrtzev. Influenza virus pathogenicity is determined by caspase cleavage motifs located in viral proteins. J Mol Genet Med (January 2009), 3(1), 124-132. Abstract
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 124-132 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Zhirnov.htm)
Almost all influenza virus proteins are found to contain caspase cleavage motifs. Two caspase cleavage consensus sequences, EXD|Y and D/EXXD|Y (caspase motifs) were identified in N- and C-terminal regions ... Mosleh, etc.,al. Molecular quantitation of H9N2 avian influenza virus in various organs of broiler chickens using TaqMan real time PCR. J Mol Genet Med (January 2009), 3(1), 152-157. Abstract
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 152-157 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Mosleh.htm)
During the past decade, H9N2 low pathogenic avian influenza virus (LPAI) has caused considerable economic loss due to decreased production, increased mortality and the cost of vaccination in Iranian poultry ... Kuchipudi, etc.,al. Differences in influenza virus receptors in chickens and ducks: Implications for interspecies transmission. J Mol Genet Med (January 2009), 3(1), 143-151. Abstract
submitted by kickingbird at Jan, 23, 2009 from J Mol Genet Med (January 2009), 3(1), 143-151 (via http://www.libpubmedia.co.uk/MedJ-Issues/Issue-4/Kuchipudi.h)
Short Report
J Mol Genet Med (January 2009), 3(1), 143-151
doi: jmgm
Published online: 16 January 2009
Full Text: (html | pdf ~1440kb | refs)
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