Pan Zhang, Raina MacIntyre. An overview of HPAI H5N1 clade 2.3.4.4b and its emerging threat in mainland Australia: Identified knowledge gaps. One Health, available online 10 December 2025. Abstract
submitted by kickingbird at 9 days ago from One Health, available online 10 December 2025 (via https://www.sciencedirect.com/science/article/pii/S235277142)
The highly pathogenic avian influenza (HPAI) H5N1 virus, particularly clade 2.3.4.4b, is currently causing a panzootic. The threat of its incursion into mainland Australia is escalating, especially following ... Pavithra Daulagala, Yonna W Y Leung, Leo L H Luk,. Anti-neuraminidase antibody responses in older adults after consecutive vaccinations with enhanced influenza vaccines: a randomized controlled trial. The Journal of Infectious Diseases, 2025;, jiaf616. Abstract
submitted by kickingbird at 9 days ago from The Journal of Infectious Diseases, 2025;, jiaf616 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
BackgroundAnti-neuraminidase antibodies have been identified as a correlate of protection for influenza virus infection. We evaluated the immunogenicity of enhanced influenza vaccines versus standard-dose ... Higerd-Rusli GP, Karan A, Hoffman SA, Morante IEA,. One confirmed and one potential human case of influenza A(H5N1) detected through an expanded subtyping protocol. ASM Case Rep 0:e00165-25. Abstract
submitted by kickingbird at 9 days ago from ASM Case Rep 0:e00165-25 (via https://journals.asm.org/doi/10.1128/asmcr.00165-25)
Current U.S. surveillance for highly pathogenic avian influenza A(H5N1) in humans prioritizes individuals with known animal exposures, potentially missing community-acquired infections. To address this ... Kar J, Hirohama M, Nakayama K, Lee S, Kawaguchi A. Microtubule detyrosination links inflammasome activation to apoptotic cell death in macrophages upon influenza A virus infection. J Virol. 2025 Dec 9:e0184725. Abstract
submitted by kickingbird at 9 days ago from J Virol. 2025 Dec 9:e0184725 (via https://journals.asm.org/doi/10.1128/jvi.01847-25)
The tubulin code, defined by diverse post-translational modifications of microtubules, fine-tunes microtubule dynamics, regulating downstream cellular signaling. Among these, detyrosination of α-tubulin ... Ganesh V, Iampietro J, Sridhar S, Goncalvez AP. Human Immune Response to Influenza Neuraminidase After Vaccination: A Systematic Review. Influenza Other Respir Viruses. 2025 Dec;19(12):e7. Abstract
submitted by kickingbird at 9 days ago from Influenza Other Respir Viruses. 2025 Dec;19(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70192)
Background: Licensed influenza vaccines primarily target hemagglutinin (HA)-related immunity, but neuraminidase (NA)-based immunity is gaining attention as an independent correlate of protection. Inactivated ... Ivan Tomic, etc.,al. [preprint]Innate antiviral readiness drives the expansion of protective T stem cell memory against influenza. https://doi.org/10.64898/2025.12.06.692757. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.64898/2025.12.06.692757 (via https://www.biorxiv.org/content/10.64898/2025.12.06.692757v1)
The development of T-cell-based influenza vaccines relies on eliciting broad CD8+ T-cell immunity, wherein T stem cell-like memory (TSCM) cells serve as the ultimate long-lived reservoir for immune memory, ... Wang X, Mao H, Kong L, Xu Z, Liu S, Ren J, Sun Z,. Clinical and epidemiological characteristics of four human cases of avian influenza virus infection in Zhejiang Province, China, 2021-2024. Infect Dis. 2025 Dec 8:1-11. Abstract
submitted by kickingbird at 9 days ago from Infect Dis. 2025 Dec 8:1-11 (via https://www.tandfonline.com/doi/full/10.1080/23744235.2025.2)
Background: Avian influenza A viruses (AIVs) remain a global public health concern. Sporadic human infections continue to be reported, particularly in areas with frequent human-poultry contact. We report ... Matteo Chiara, etc.,al. [preprint]Distinctive viral genome signatures are linked to repeated mammalian spillovers of H5N1 in North America. https://doi.org/10.64898/2025.12.09.693147. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.64898/2025.12.09.693147 (via https://www.biorxiv.org/content/10.64898/2025.12.09.693147v1)
Highly pathogenic avian influenza H5N1 rarely infects mammals. In 2024-2025, however, genotypes B3.13 and D1.1 caused two independent spillovers into U.S. dairy cattle. By analysing 26,930 complete H5N1 ... Wang X, Liu X, Wang S, Wang Q, Wang J, Wang M, Yao. Identification of the Key Amino Acid Mutations in the PB2 and PA Proteins of Classical Swine H1N1 Influenza A Virus in Mammalian Adaptation. Emerg Microbes Infect. 2025 Dec 9:2602310. Abstract
submitted by kickingbird at 9 days ago from Emerg Microbes Infect. 2025 Dec 9:2602310 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The classical swine (CS) H1N1 influenza virus firstly isolated in 1930 is highly homologous to the 1918 Spanish influenza virus. CS H1N1 virus crossed the interspecies barrier to infect humans has become ... Nájera F, Uiterwaal S, Garcelon DK, Randolph JF, V. Impacts of infectious diseases on movement metrics in a large carnivore: Highly pathogenic avian influenza, leptospirosis, and pumas. iScience. 2025 Oct 17;28(11):113810. Abstract
submitted by kickingbird at 9 days ago from iScience. 2025 Oct 17;28(11):113810 (via https://www.cell.com/iscience/fulltext/S2589-0042(25)02071-1)
Understanding how behavior and movement are affected during the clinical stages of infectious disease in hosts provides stronger insight into activity patterns. We identified changes in movement and behavioral ... Zhang J, Wu H, Wang P, Fu J, Zheng X, Wan F, Hu M. Smartphone-assisted upconversion nanoparticle assay for rapid multiplex detection of H5, H7, and H10 avian influenza viruses. Emerg Microbes Infect. 2025 Dec 9:2602315. Abstract
submitted by kickingbird at 9 days ago from Emerg Microbes Infect. 2025 Dec 9:2602315 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Avian influenza viruses (AIVs) of the H5, H7, and H10 subtypes pose substantial threats to global public health owing to their high pathogenicity, cross-species transmissibility, and potential to spark ... Wang Y, Shang J, Yu M, Liu G, Liu X, Wang F. A Label-Free Phosphate-Transfer DNAzyme for the Cost-Effective Point-of-Care Detection of Influenza Virus. Angew Chem Int Ed Engl. 2025 Dec 9:e16920. Abstract
submitted by kickingbird at 9 days ago from Angew Chem Int Ed Engl. 2025 Dec 9:e16920 (via https://onlinelibrary.wiley.com/doi/10.1002/anie.202516920)
DNAzymes have significantly enriched the toolbox for point-of-care testing (POCT); however, their inferior biostability and reliance on costly chemical labeling limit their broader applicability in high-throughput ... Rihn A, Bhusal NR, Zaring Weir C, Eckelkamp E. Sociodemographic characteristics that impact southeastern US consumers´ awareness and concern about highly pathogenic avian influenza in dairy products. JDS Commun. 2025 Sep 17;6(6):738-743. Abstract
submitted by kickingbird at 11 days ago from JDS Commun. 2025 Sep 17;6(6):738-743 (via https://www.jdscommun.org/article/S2666-9102(25)00144-9/full)
The highly pathogenic avian influenza H5N1 (HPAI) has recently been identified in the dairy industry in the United States. Research has addressed consumer behavior in the context of HPAI among poultry ... Lee K, Song D, Lyoo KS. Mammalian adaptation and zoonotic risk of influenza A viruses in companion animals. J Vet Sci. 2025 Nov;26(6):e80. Abstract
submitted by kickingbird at 11 days ago from J Vet Sci. 2025 Nov;26(6):e80 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.25153)
Importance: Since the early 2000s, companion animals emerged as unexpected players in influenza A virus ecology. Canine influenza viruses and the increasing detection of highly pathogenic avian influenza ... Richard A. Neher, etc.,al. [preprint]Nomenclature for tracking of genetic variation of seasonal influenza viruses. https://doi.org/10.64898/2025.12.06.25341755. Abstract
submitted by kickingbird at 11 days ago from https://doi.org/10.64898/2025.12.06.25341755 (via https://www.medrxiv.org/content/10.64898/2025.12.06.25341755)
Background: Genomic surveillance of human seasonal influenza viruses is an essential component of the Global Influenza Surveillance and Response system (GISRS) and informs the recommendations for the seasonal ... Li, ZN., Liu, F., Jung, YJ. et al. Pre-existing cross-reactive immunity to highly pathogenic avian influenza 2.3.4.4b A(H5N1) virus in the United States. Nat Commun 16, 10954 (2025). Abstract
submitted by kickingbird at 11 days ago from Nat Commun 16, 10954 (2025) (via https://link.springer.com/article/10.1038/s41467-025-66431-2)
The unprecedented 2.3.4.4b. A(H5N1) outbreak in dairy cattle, poultry, and spillover to humans in the United States (US) poses a major public health threat. Population immunity is a critical component ... Son, SE., An, SH., Lee, CY. et al. Evolutionary trajectories and zoonotic potential of a PB2 mutation triad (I147T, K339T, and A588T) in avian influenza viruses. Vet Res (2025). Abstract
submitted by kickingbird at 11 days ago from Vet Res (2025) (via https://link.springer.com/article/10.1186/s13567-025-01680-z)
Efficient replication of influenza A viruses (IAVs) requires balanced activities of hemagglutinin (HA), neuraminidase (NA), and the RNA polymerase complex, whose functions are strongly influenced by PB2 ... Agustina Rimondi, etc.,al. [preprint]Persistence and spillback of mammal-adapted H5N1 genotype B3.2 viruses among South American seabirds and marine mammals. https://doi.org/10.21203/rs.3.rs-7960151/v1. Abstract
submitted by kickingbird at 11 days ago from https://doi.org/10.21203/rs.3.rs-7960151/v1 (via https://www.researchsquare.com/article/rs-7960151/v1)
The arrival of H5N1 clade 2.3.4.4b genotype B3.2 in South America marks an unprecedented geographic expansion of highly pathogenic avian influenza viruses. The continent remains the only region with sustained ... Wang, X., Zhang, X., Chen, C. et al. Comparison of efficacy, safety, immune response of dNS1 LAIV and cold-adapted LAIV in a mouse model. npj Vaccines (2025). Abstract
submitted by kickingbird at 11 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01320-9)
Influenza remains a significant global public health concern. Live-attenuated influenza vaccines (LAIVs) are recognized as effective interventions for influenza prevention. Currently, two types of LAIVs ... Douros A, Cui Y, Dell´Aniello S, Suissa S, B. Influenza Immunization at Midlife and the Risk of Parkinson Disease. JAMA Netw Open. 2025 Dec 1;8(12):e2547140. Abstract
submitted by kickingbird at 11 days ago from JAMA Netw Open. 2025 Dec 1;8(12):e2547140 (via https://jamanetwork.com/journals/jamanetworkopen/fullarticle)
Importance: Influenza infection could be associated with a long-term increase in the risk of Parkinson disease (PD). However, the benefit of influenza immunization as a preventive measure for PD remains ... 9563 items, 20/Page, Page[3/479][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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