José Carlos Mancera Gracia, etc.,al. A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine. Scientific Reports 7, Article number: 1323 (2017). Abstract
submitted by kickingbird at May, 4, 2017 from Scientific Reports 7, Article number: 1323 (2017) (via http://www.nature.com/articles/s41598-017-01512-x)
Avian H9N2 and 2009 pandemic H1N1 (pH1N1) influenza viruses can infect pigs and humans, raising the concern that H9N2:pH1N1 reassortant viruses could emerge. Such reassortants demonstrated increased replication ... Nakatsukasa A, Kuruma K, Okamatsu M, Hiono T, et a. Potency of whole virus particle and split virion vaccines using dissolving microneedle against challenges of H1N1 and H5N1 influenza viruses in mice. Vaccine 2017 Apr 18.. Abstract
submitted by kickingbird at May, 4, 2017 from Vaccine 2017 Apr 18. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28446669/)
Transdermal vaccination using a microneedle (MN) confers enhanced immunity compared with subcutaneous (SC) vaccination. Here we developed a novel dissolving MN patch for the influenza vaccine. The potencies ... Ivinson K, Deliyannis G, McNabb L, Grollo L, et al. Salivary blockade protects the lower respiratory tract of mice from lethal influenza. J Virol 2017 Apr 26.. Abstract
submitted by kickingbird at May, 4, 2017 from J Virol 2017 Apr 26. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28446669/)
It is possible to model progression of influenza virus from the upper respiratory tract to the lower respiratory tract in the mouse using viral inoculum delivered in a restricted manner to the nose. In ... IZZARD L, Dlugolenski D, Xia Y, McMahon M, et al.. Enhanced immunogenicity following miR-155 incorporation into the influenza A virus genome. Virus Res. 2017 Apr 6. pii: S0168-1702(16)30814. Abstract
submitted by kickingbird at Apr, 20, 2017 from Virus Res. 2017 Apr 6. pii: S0168-1702(16)30814 (via https://www.ncbi.nlm.nih.gov/pubmed/28392443)
Influenza A vaccine efficacy in the elderly is generally poor and so identification of novel molecular adjuvants to improve immunogenicity is important to reduce the overall burden of disease. Short non-coding ... CHUTIWITOONCHAI N, Mano T, Kakisaka M, Sato H, et. Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development. Virology. 2017;507:32-39. Abstract
submitted by kickingbird at Apr, 20, 2017 from Virology. 2017;507:32-39 (via https://www.ncbi.nlm.nih.gov/pubmed/28399435)
An anti-influenza compound, DP2392-E10 based on inhibition of the nuclear export function of the viral nucleoprotein-nuclear export signal 3 (NP-NES3) domain was successfully identified by our previous ... HENDIN HE, Pillet S, Lara AN, Wu CY, et al. Plant-made virus-like particle vaccines bearing the hemagglutinin of either seasonal (H1) or avian (H5) influenza have distinct patterns of interaction with human immune cells in vitro. Vaccine. 2017 May 2;35(19):2592-2599.. Abstract
submitted by kickingbird at Apr, 20, 2017 from Vaccine. 2017 May 2;35(19):2592-2599. (via https://www.ncbi.nlm.nih.gov/pubmed/28389100)
INTRODUCTION: The recent emergence of avian influenza strains has fuelled concern about pandemic preparedness since vaccines targeting these viruses are often poorly immunogenic. Weak antibody responses ... TZARUM N, McBride R, Nycholat CM, Paulson JC, et a. Unique structural features of influenza H15 HA. J Virol. 2017 Apr 12. Abstract
submitted by kickingbird at Apr, 20, 2017 from J Virol. 2017 Apr 12 (via https://www.ncbi.nlm.nih.gov/pubmed/28404848)
Influenza A H15 viruses are members of a subgroup (H7-H10-H15) of group 2 hemagglutinin (HA) subtypes that include H7N9 and H10N8 viruses that were isolated from humans during 2013. The isolation of avian ... Gronsang D, Bui AN, Trinh DQ, Bui VN, et al.. Characterization of cross-clade monoclonal antibodies against H5N1 highly pathogenic avian influenza virus and their application to the antigenic analysis of diverse H5 subtype viruses. Arch Virol 2017 Apr 12. doi: 10.1007/s00705-017-33. Abstract
submitted by kickingbird at Apr, 20, 2017 from Arch Virol 2017 Apr 12. doi: 10.1007/s00705-017-33 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28405766/)
H5N1 highly pathogenic avian influenza viruses (HPAIVs) are a threat to both animal and public health and require specific and rapid detection for prompt disease control. We produced three neutralizing ... Wang Y, Wu J, Xue C, Wu Z, et al. A recombinant H7N9 influenza vaccine with the H7 hemagglutinin transmembrane domain replaced by the H3 domain induces increased cross-reactive antibodies and improved interclade protection in mice. Antiviral Res 2017 Apr 10. pii: S0166-3542(16)3079. Abstract
submitted by kickingbird at Apr, 20, 2017 from Antiviral Res 2017 Apr 10. pii: S0166-3542(16)3079 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28408133/)
Influenza A H7N9 virus is the latest emerging pandemic threat, and has rapidly diverged into three clades, demanding a H7N9 virus vaccine with broadened protection against unmatched strains. Hemagglutinin ... Hui Jiang, etc.,al. Preliminary epidemiologic assessment of human infections with highly pathogenic avian influenza A(H5N6) virus, China. Clin Infect Dis cix334. Abstract
submitted by kickingbird at Apr, 18, 2017 from Clin Infect Dis cix334 (via https://academic.oup.com/cid/article-abstract/doi/10.1093/ci)
BackgroundSince 2014, 17 human cases of infection with the newly emerged highly pathogenic avian influenza A(H5N6) virus have been identified in China to date. The epidemiologic characteristics of laboratory-confirmed ... Salaheldin AH,etc.,al. Isolation and genetic characterization of a novel 2.2.1.2a H5N1 virus from a vaccinated meat-turkeys flock in Egypt. Virol J. 2017 Mar 9;14(1):48. Abstract
submitted by kickingbird at Apr, 16, 2017 from Virol J. 2017 Mar 9;14(1):48 (via http://virologyj.biomedcentral.com/articles/10.1186/s12985-0)
AbstractBackgroundVaccination of poultry to control highly pathogenic avian influenza virus (HPAIV) H5N1 is used in several countries. HPAIV H5N1 of clade 2.2.1 which is endemic in Egypt has diversified ... Wu ZQ,etc.,al. Comparative Epidemiology of Human Fatal Infections with Novel, High (H5N6 and H5N1) and Low (H7N9 and H9N2) Pathogenicity Avian Influenza A Viruses. Int. J. Environ. Res. Public Health 2017, 14(3), 2. Abstract
submitted by kickingbird at Apr, 16, 2017 from Int. J. Environ. Res. Public Health 2017, 14(3), 2 (via http://www.mdpi.com/1660-4601/14/3/263)
This study aimed to assess the mortality risks for human infection with high (HPAI) and low (LPAI) pathogenicity avian influenza viruses. The HPAI case fatality rate (CFR) was far higher than the LPAI ... Atkinson KV,etc.,al. Influenza C in Lancaster, UK, in the winter of 2014~2015. Scientific Reports 7, Article number: 46578 (2017). Abstract
submitted by kickingbird at Apr, 16, 2017 from Scientific Reports 7, Article number: 46578 (2017) (via https://www.nature.com/articles/srep46578)
Influenza C is not included in the annual seasonal influenza vaccine, and has historically been regarded as a minor respiratory pathogen. However, recent work has highlighted its potential role as a cause ... Netanel Tzarum,etc.,al. Unique structural features of influenza H15 HA. J Virol. 2017 Apr 12. pii: JVI.00046-17.. Abstract
submitted by kickingbird at Apr, 16, 2017 from J Virol. 2017 Apr 12. pii: JVI.00046-17. (via http://jvi.asm.org/content/early/2017/04/06/JVI.00046-17)
Influenza A H15 viruses are members of a subgroup (H7-H10-H15) of group 2 hemagglutinin (HA) subtypes that include H7N9 and H10N8 viruses that were isolated from humans during 2013. The isolation of avian ... Yingying Du,etc.,al. Molecular Evolution and Emergence of H5N6 Avian Influenza Virus in Central China. J Virol. 2017 Apr 12.. Abstract
submitted by kickingbird at Apr, 16, 2017 from J Virol. 2017 Apr 12. (via http://jvi.asm.org/content/early/2017/04/06/JVI.00143-17)
H5N6 avian influenza virus (AIV) has posed a potential threat to public health since its emergence in China in 2013. To understand the evolution and emergence of H5N6 in the avian population we performed ... Netanel Tzarum,etc.,al. The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus. Cell Rep. 2017 Apr 11;19(2):235-245.. Abstract
submitted by kickingbird at Apr, 16, 2017 from Cell Rep. 2017 Apr 11;19(2):235-245. (via http://www.cell.com/cell-reports/abstract/S2211-1247(17)3040)
Adaptation of influenza A viruses to new hosts are rare events but are the basis for emergence of new influenza pandemics in the human population. Thus, understanding the processes involved in such events ... Elma H. Akand, Kevin.M. Downard. Mutational Analysis Employing a Phylogenetic Mass Tree Approach in a Study of the Evolution of the Influenza Virus. Mol Phylogenet Evol. 2017 Apr 8. Abstract
submitted by kickingbird at Apr, 16, 2017 from Mol Phylogenet Evol. 2017 Apr 8 (via http://www.sciencedirect.com/science/article/pii/S1055790317)
A mass based approach has been advanced to enable mutations associated with the evolution of proteins to be both charted and interrogated using phylogenetic trees built solely from the masses of peptides ... Hailiang Sun,etc.,al. Pathogenicity and transmission of a swine influenza A(H6N6) virus. Emerging Microbes & Infections (2017) 6, e17;. Abstract
submitted by kickingbird at Apr, 16, 2017 from Emerging Microbes & Infections (2017) 6, e17; (via http://www.nature.com/emi/journal/v6/n4/full/emi20173a.html)
Subtype H6 influenza A viruses (IAVs) are commonly detected in wild birds and domestic poultry and can infect humans. In 2010, a H6N6 virus emerged in southern China, and since then, it has caused sporadic ... Deeg CM,etc.,al. In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein. J Exp Med. 2017 Apr 10.. Abstract
submitted by kickingbird at Apr, 16, 2017 from J Exp Med. 2017 Apr 10. (via http://jem.rupress.org/content/early/2017/04/07/jem.20161033)
Zoonotic transmission of influenza A viruses can give rise to devastating pandemics, but currently it is impossible to predict the pandemic potential of circulating avian influenza viruses. Here, we describe ... Wang L,etc.,al. The NS1 protein of H5N6 feline influenza virus inhibits feline beta interferon response by preventing NF-κB and IRF3 activation. Dev Comp Immunol. 2017 Apr 7. Abstract
submitted by kickingbird at Apr, 16, 2017 from Dev Comp Immunol. 2017 Apr 7 (via http://www.sciencedirect.com/science/article/pii/S0145305X16)
Despite the apparent lack of a feline influenza virus lineage, cats are susceptible to infection by influenza A viruses. Here, we characterized in vitro A/feline/Guangdong/1/2015, an H5N6 avian influenza ... 8128 items, 20/Page, Page[266/407][|<<] [|<] [261] [262] [263] [264] [265] [266] [267] [268] [269] [270] [>|] [>>|] |
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