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2025-12-20 1:25:07
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Zhang H, Gong Z, Peng N, Wan M, Tan J, Chen C. Disease burden of seasonal influenza in China from 2010 to 2019: A systematic review and meta-analysis based on multiple indicators. Hum Vaccin Immunother. 2025 Dec;21(1):2550092.  Abstract  
submitted by kickingbird at Aug, 28, 2025 from Hum Vaccin Immunother. 2025 Dec;21(1):2550092 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2025.2)
Through systematic review and meta-analysis, the average annual disease burden of seasonal influenza in China from 2010 to 2019 was estimated, and the differences between the northern and the southern ...

Guo Y, Shu S, Zhou Y, Peng W, Jiang Z, Li Y, Li T,. An emerging PB2-627 polymorphism increases the zoonotic risk of avian influenza virus by overcoming ANP32 host restriction in mammalian and avian hosts. J Virol. 2025 Aug 27:e0085325.  Abstract  
submitted by kickingbird at Aug, 28, 2025 from J Virol. 2025 Aug 27:e0085325 (via https://journals.asm.org/doi/10.1128/jvi.00853-25)
Alterations in the PB2-627 domain of avian influenza virus (AIV) can potentially increase the risk of cross-host species infections in humans and mammals. Recently, there has been a rise in human cases ...

van der Wal FJ, Pritz-Verschuren SBE, Germeraad EA. Evaluation of commercial rapid tests for fast and on-site detection of high-pathogenicity avian influenza H5 virus in poultry. Microbiol Spectr. 2025 Aug 27:e0065425.  Abstract  
submitted by kickingbird at Aug, 28, 2025 from Microbiol Spectr. 2025 Aug 27:e0065425 (via https://journals.asm.org/doi/10.1128/spectrum.00654-25)
Since 2016, numerous outbreaks of high-pathogenicity avian influenza (HPAI) have occurred on poultry farms in Europe. Samples from suspected outbreaks are investigated using PCR at the national reference ...

Zhao X, Gao J, Gu Y, Teng Z, Zhang X, Wu H, Chen X. LAMP-Based 4-Channel Microfluidic Chip for POCT Detection of Influenza A H1N1, H3N2, and Influenza B Victoria Viruses. Biosensors (Basel). 2025 Aug 4;15(8):506.  Abstract  
submitted by kickingbird at Aug, 28, 2025 from Biosensors (Basel). 2025 Aug 4;15(8):506 (via https://www.mdpi.com/2079-6374/15/8/506)
Background: Influenza viruses are major pathogens responsible for respiratory infections and pose significant risks to densely populated urban areas. RT-qPCR has made substantial contributions in controlling ...

Gertz A, Sopko JB, Remmel C, Rader B, Brownstein J. Assessment of Influenza Testing Distribution in the United States for the 2021-2022, 2022-2023, and 2023-2024 Influenza Seasons: Online Cross-Sectional Study. JMIR Public Health Surveill. 2025 Aug 26;11:e76459.  Abstract  
submitted by kickingbird at Aug, 27, 2025 from JMIR Public Health Surveill. 2025 Aug 26;11:e76459 (via https://publichealth.jmir.org/2025/1/e76459)
Background: Effective surveillance of seasonal influenza is crucial to understanding disease burden and impact. Traditional surveillance accounts for those who interact with the health care system, including ...

Jiang Y, Shen Y, Zhang Q, Liu Z, Liu Y, Peng J, Ya. Influenza A Virus (H1N1) Infection Induces Ferroptosis to Promote Developmental Injury in Fetal Tissues. Cell Prolif. 2025 Aug 26:e70117.  Abstract  
submitted by kickingbird at Aug, 27, 2025 from Cell Prolif. 2025 Aug 26:e70117 (via https://onlinelibrary.wiley.com/doi/10.1111/cpr.70117)
H1N1, a globally pervasive subtype of influenza A virus (IAV), poses an ongoing threat to human health and occasionally leads to multi-organ dysfunction in severe cases. Evidence confirms that the H1N1 ...

Shi X, Fang S, Du C, Luo G, Cheng Y, Zhang Z, Lv Q. Wastewater-based epidemiology of influenza A virus in Shenzhen: baseline values and implications for multi-pathogen surveillance. Emerg Microbes Infect. 2025 Aug 25:2552724.  Abstract  
submitted by kickingbird at Aug, 27, 2025 from Emerg Microbes Infect. 2025 Aug 25:2552724 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A virus (IAV) has become increasingly unpredictable in its seasonal patterns following the COVID-19 pandemic. A key challenge remains identifying optimal moments for public health interventions ...

Marotta MG, Neto MM, Daly J, Maina M, van Diemen P. Development and optimisation of Influenza C and Influenza D pseudotyped viruses. J Virol Methods . 2025 Aug 23:115243.  Abstract  
submitted by kickingbird at Aug, 27, 2025 from J Virol Methods . 2025 Aug 23:115243 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
To facilitate the study of influenza C (ICV) and influenza D (IDV) viruses, we generated lentiviral pseudotyped viruses (PVs) expressing the hemagglutinin-esterase fusion (HEF) glycoprotein from ICV (C/Minnesota/33/2015) ...

Pohl MO, Violaki K, Liu L, Gaggioli E, Glas I, von. Comparative characterization of bronchial and nasal mucus reveals key determinants of influenza A virus inhibition. mSphere. 2025 Aug 25:e0036525.  Abstract  
submitted by kickingbird at Aug, 26, 2025 from mSphere. 2025 Aug 25:e0036525 (via https://journals.asm.org/doi/10.1128/msphere.00365-25)
Differentiated primary human respiratory epithelial cells grown at air-liquid interface have become a widely used cell culture model of the human conducting airways. These cultures contain secretory cells ...

Robinson-McCarthy LR, Simmons HC, Graber AL, Marbl. Dairy cattle herds mount a characteristic antibody response to highly pathogenic H5N1 avian influenza viruses. J Virol. 2025 Aug 25:e0062125.  Abstract  
submitted by kickingbird at Aug, 26, 2025 from J Virol. 2025 Aug 25:e0062125 (via https://journals.asm.org/doi/10.1128/jvi.00621-25)
An unprecedented outbreak of a highly pathogenic avian influenza virus, H5 clade 2.3.4.4b, was reported in U.S. dairy cattle during the spring of 2024. It has now spread to hundreds of herds across multiple ...

Yang Y, Guo K, Xu L, Guo W, Dong M, Liu W, Li S, Z. Development and application of a NP-cELISA for the detection of nucleoprotein antibodies of equine influenza virus. Microbiol Spectr. 2025 Aug 25:e0093925.  Abstract  
submitted by kickingbird at Aug, 26, 2025 from Microbiol Spectr. 2025 Aug 25:e0093925 (via https://journals.asm.org/doi/10.1128/spectrum.00939-25)
Equine influenza (EI), caused by the equine influenza virus (EIV), is an acute respiratory disease that has become enzootic worldwide, resulting in frequent outbreaks and substantial economic losses within ...

Yuying Liang, Jian Chen, Shiyun Ma, Haoru Song, Da. Ultrafast Tyrosinase-Mediated Biotinylation of Living Cell Surface Analysis Reveals Novel Cell Surface Proteins Responsible for Influenza A Virus Entry. Journal of the American Chemical Society.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Journal of the American Chemical Society (via https://pubs.acs.org/doi/10.1021/jacs.5c12360)
Cell surface proteins are integral to a myriad of biological processes, including cell–cell interactions, signal transduction, and cell adhesion. Notably, these proteins also serve as key receptors for ...

Brenda Aline Maya Badillo, etc.,al. H5N1 highly pathogenic avian influenza vaccination: Seroresponse of mexican poultry in the 2022-2024. Vaccine: X, 23 Aug 2025, 100709.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Vaccine: X, 23 Aug 2025, 100709 (via https://www.sciencedirect.com/science/article/pii/S259013622)
Since 2021, the activity and impact of the highly pathogenic H5N1 avian influenza virus have intensified worldwide, causing high mortality in wild birds and birds while also infecting various wild and ...

Anika John, etc.,al. Characterizing Influenza A Virus Lineages and Clinically Relevant Mutations Through High-Coverage Wastewater Sequencing. Water Research. 21 Aug 2025, 124453.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Water Research. 21 Aug 2025, 124453 (via https://www.sciencedirect.com/science/article/pii/S004313542)
Influenza A virus poses significant public health challenges, causing seasonal outbreaks and pandemics. Its rapid evolution motivates continuous monitoring of circulating influenza genomes to inform vaccine ...

Shengjun Bu, etc.,al. A lateral flow biosensor based on a novel isothermal amplification method for visual identification of the influenza virus H1N1. Microchemical Journal. 21 Aug 2025, 114953.  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Microchemical Journal. 21 Aug 2025, 114953 (via https://www.sciencedirect.com/science/article/abs/pii/S00262)
Here, we developed a novel single primer-amplification (SPA) method for detection of nucleic acids that requires only two primers and one enzyme. The primer was extended into long ssDNA products with tandem ...

Paran, N., Wirblich, C., Olal, C. et al. Immunogenicity and safety of a rabies-based highly pathogenic influenza A virus H5 vaccine in cattle. npj Vaccines 10, 197 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from npj Vaccines 10, 197 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01238-2)
The circulation of highly pathogenic H5 influenza A viruses in cattle, other mammals, and wildlife threatens animal and human health. To address this, we vaccinated heifer-calves with a deactivated rabies-virus-based ...

Hu, M., Luo, N., Wang, B. et al. Flu-CNN: identifying host specificity of Influenza A virus using convolutional networks. Hum Genomics 19, 96 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Hum Genomics 19, 96 (2025) (via https://link.springer.com/article/10.1186/s40246-025-00812-y)
Influenza A viruses (IAVs) have historically posed significant public health threats, causing severe pandemics. Viral host specificity is typically constrained by host barriers, limiting the range of species ...

Piltch-Loeb, R., Gibbs, S.G., Lowe, J.J. et al. U.S. trust in physicians as key public health messengers during the H5N1 avian influenza outbreak. Sci Rep 15, 31011 (2025).  Abstract  
submitted by kickingbird at Aug, 24, 2025 from Sci Rep 15, 31011 (2025) (via https://link.springer.com/article/10.1038/s41598-025-12304-z)
The emerging threat of H5N1 avian influenza in humans has renewed the need for effective public health communication strategies, especially in light of reduced public trust in governmental institutions. ...

Arroyave A, Rabezanahary H, Wantchecon A, Rahajama. Assessment of Cross-Reactive Neutralizing Antibodies Induction Against H5N1 Clade 2.3.4.4b by Prior Seasonal Influenza Immunization in Retail Workers. Open Forum Infect Dis. 2025 Aug 20;12(8):ofaf463.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from Open Forum Infect Dis. 2025 Aug 20;12(8):ofaf463 (via https://academic.oup.com/ofid/article/12/8/ofaf463/8238501)
This study evaluated whether immunity from seasonal influenza induces cross-reactive antibodies against recent avian and bovine H5N1 strains in serum from retail workers. Despite strong neutralizing activity ...

Ramya S. Barre, etc.,al. A Human H5N1 Influenza Virus Expressing Bioluminescence for Evaluating Viral Infection and Identifying Therapeutic Interventions. iScience. 21 Aug 2025, 113402.  Abstract  
submitted by kickingbird at Aug, 23, 2025 from iScience. 21 Aug 2025, 113402 (via https://www.sciencedirect.com/science/article/pii/S258900422)
A multistate outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in the United States dairy cattle was first reported on March 2024, followed by a zoonotic cattle-to-human virus transmission ...

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