Liu T, Reiser WK, Tan TJC, Lv H, Rivera-Cardona J,. Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin. Virus Evol. 2024 Jun 19;10(1):veae046. Abstract
submitted by kickingbird at Jun, 25, 2024 from Virus Evol. 2024 Jun 19;10(1):veae046 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The antigenic evolution of the influenza A virus hemagglutinin (HA) gene poses a major challenge for the development of vaccines capable of eliciting long-term protection. Prior efforts to understand the ... Wu W, Alexander JS, Booth JL, Miller CA, Metcalf J. Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice. Immun Ageing. 2024 Jun 21;21(1):39. Abstract
submitted by kickingbird at Jun, 24, 2024 from Immun Ageing. 2024 Jun 21;21(1):39 (via https://immunityageing.biomedcentral.com/articles/10.1186/s1)
Background: Age > 65 years is a key risk factor for poor outcomes after human influenza infection. Specifically, in addition to respiratory disease, non-neurotropic influenza A virus (IAV) causes neuro-cognitive ... Takadate Y, Mine J, Tsunekuni R, Sakuma S, Kumagai. Genetic diversity of H5N1 and H5N2 high pathogenicity avian influenza viruses isolated from poultry in Japan during the winter of 2022-2023. Virus Res. 2024 Jun 19:199425. Abstract
submitted by kickingbird at Jun, 23, 2024 from Virus Res. 2024 Jun 19:199425 (via https://pubmed.ncbi.nlm.nih.gov/38906223/)
High pathogenicity avian influenza viruses (HPAIVs) of the H5N1 and H5N2 subtypes were responsible for 84 HPAI outbreaks on poultry premises in Japan during October 2022-April 2023. The number of outbreaks ... Dandachi I, Alrezaihi A, Amin D, AlRagi N, Alhatla. Molecular surveillance of influenza A virus in Saudi Arabia: whole-genome sequencing and metagenomic approaches. Microbiol Spectr. 2024 Jun 21:e0066524. Abstract
submitted by kickingbird at Jun, 22, 2024 from Microbiol Spectr. 2024 Jun 21:e0066524 (via https://journals.asm.org/doi/epub/10.1128/spectrum.00665-24)
Outbreaks of influenza A viruses are generally seasonal and cause annual epidemics worldwide. Due to their frequent reassortment and evolution, annual surveillance is of paramount importance to guide vaccine ... Kareinen Lauri, Tammiranta Niina, Kauppinen Ari, Z. Highly pathogenic avian influenza A(H5N1) virus infections on fur farms connected to mass mortalities of black-headed gulls, Finland, July to October 2023. Euro Surveill. 2024;29(25):pii=2400063. Abstract
submitted by kickingbird at Jun, 21, 2024 from Euro Surveill. 2024;29(25):pii=2400063 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Highly pathogenic avian influenza (HPAI) has caused widespread mortality in both wild and domestic birds in Europe 2020–2023. In July 2023, HPAI A(H5N1) was detected on 27 fur farms in Finland. In total, ... J Nuzzo, etc.,al. The United States Needs A Better Testing Playbook For Future Public Health Emergencies. https://doi.org/10.1377/hlthaff.2024.00038. Abstract
submitted by kickingbird at Jun, 21, 2024 from https://doi.org/10.1377/hlthaff.2024.00038 (via https://www.healthaffairs.org/doi/10.1377/hlthaff.2024.00038)
The absence of a comprehensive national playbook for developing and deploying testing has hindered the United States’ ability to rapidly suppress recent biological emergencies (for example, the COVID-19 ... Wrotek, A., Jackowska, T. A noninferiority randomized open-label pilot study of 3- versus 7-day influenza postexposure prophylaxis with oseltamivir in hospitalized children. Sci Rep 14, 14192 (2024). Abstract
submitted by kickingbird at Jun, 21, 2024 from Sci Rep 14, 14192 (2024) (via https://www.nature.com/articles/s41598-024-65244-5)
Short influenza postexposure prophylaxis (PEP) showed high efficacy in adults, but studies in children are lacking. This randomized open-label pilot trial aimed to verify noninferiority of a 3- versus ... Prosser, D.J., Kent, C.M., Sullivan, J.D. et al. Using an adaptive modeling framework to identify avian influenza spillover risk at the wild-domestic interface. Sci Rep 14, 14199 (2024). Abstract
submitted by kickingbird at Jun, 21, 2024 from Sci Rep 14, 14199 (2024) (via https://www.nature.com/articles/s41598-024-64912-w)
The wild to domestic bird interface is an important nexus for emergence and transmission of highly pathogenic avian influenza (HPAI) viruses. Although the recent incursion of HPAI H5N1 Clade 2.3.4.4b into ... Sun Y, Wagatsuma K, Saito R, Sato I, Kawashima T,. Duration of fever in children infected with influenza A(H1N1)pdm09, A(H3N2) or B virus and treated with baloxavir marboxil, oseltamivir, laninamivir, or zanamivir in Japan during the 2012-2013 and 201. Antiviral Res. 2024 Jun 17:105938. Abstract
submitted by kickingbird at Jun, 20, 2024 from Antiviral Res. 2024 Jun 17:105938 (via https://www.sciencedirect.com/science/article/pii/S016635422)
We compared the duration of fever in children infected with A(H1N1)pdm09, A(H3N2), or influenza B viruses following treatment with baloxavir marboxil (baloxavir) or neuraminidase inhibitors (NAIs) (oseltamivir, ... Adesola RO, Onoja BA, Adamu AM, Agbaje ST, Abdulaz. Molecular epidemiology and genetic evolution of avian influenza H5N1 subtype in Nigeria, 2006 to 2021. Virus Genes. 2024 Jun 19. Abstract
submitted by kickingbird at Jun, 20, 2024 from Virus Genes. 2024 Jun 19 (via https://link.springer.com/article/10.1007/s11262-024-02080-9)
Nigeria recorded one of the earliest outbreaks of the Highly Pathogenic Avian Influenza (HPAI) virus H5N1 in 2006, which spread to other African countries. In 2023, 18 countries reported outbreaks of H5N1 ... Edler P, Schwab LSU, Aban M, Wille M, Spirason N,. Immune imprinting in early life shapes cross-reactivity to influenza B virus haemagglutinin. Nat Microbiol. 2024 Jun 18. Abstract
submitted by kickingbird at Jun, 19, 2024 from Nat Microbiol. 2024 Jun 18 (via https://www.nature.com/articles/s41564-024-01732-8)
Influenza exposures early in life are believed to shape future susceptibility to influenza infections by imprinting immunological biases that affect cross-reactivity to future influenza viruses. However, ... Lei R, Liang W, Ouyang WO, Hernandez Garcia A, Kik. Epistasis mediates the evolution of the receptor binding mode in recent human H3N2 hemagglutinin. Nat Commun. 2024 Jun 18;15(1):5175. Abstract
submitted by kickingbird at Jun, 19, 2024 from Nat Commun. 2024 Jun 18;15(1):5175 (via https://www.nature.com/articles/s41467-024-49487-4)
The receptor-binding site of influenza A virus hemagglutinin partially overlaps with major antigenic sites and constantly evolves. In this study, we observe that mutations G186D and D190N in the hemagglutinin ... Jun He, Lei Gong, Xiaolong Chen, Deman Cheng, Sai. Outbreak Reports: A Retrospective Investigation of a Case of Dual Infection by Avian-Origin Influenza A (H10N5) and Seasonal Influenza A (H3N2) Viruses — Anhui Province, China, December 2023–January 2. China CDC Weekly. Abstract
submitted by kickingbird at Jun, 19, 2024 from China CDC Weekly (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024)
On January 23, 2024, the Anhui provincial CDC received a cooperation report from the Zhejiang provincial CDC and subsequently initiated a retrospective epidemiological study to investigate the epidemiology, ... Karakus U, etc.,al. H19 influenza A virus exhibits species-specific MHC class II receptor usage. Cell Host & Microbe. Abstract
submitted by kickingbird at Jun, 18, 2024 from Cell Host & Microbe (via https://www.cell.com/cell-host-microbe/abstract/S1931-3128(2)
Avian influenza A virus (IAV) surveillance in Northern California, USA, revealed unique IAV hemagglutinin (HA) genome sequences in cloacal swabs from lesser scaups. We found two closely related HA sequences ... Zhu W, Gu L. Resurgence of seasonal influenza driven by A/H3N2 and B/Victoria in succession during the 2023-2024 season in Beijing showing increased population susceptibility. J Med Virol. 2024 Jun;96(6):e29751. Abstract
submitted by kickingbird at Jun, 18, 2024 from J Med Virol. 2024 Jun;96(6):e29751 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29751)
During the COVID-19 pandemic, non-pharmaceutical interventions were introduced to reduce exposure to respiratory viruses. However, these measures may have led to an "immunity debt" that could make the ... Zhang T, Han Y, Huang W, Wei H, Zhao Y, Shu L, Guo. Neutralizing antibody responses against contemporary and future influenza A(H3N2) viruses in paradoxical clades elicited by repeated and single vaccinations. J Med Virol. 2024 Jun;96(6):e29743. Abstract
submitted by kickingbird at Jun, 18, 2024 from J Med Virol. 2024 Jun;96(6):e29743 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29743)
As one of the most effective measures to prevent seasonal influenza viruses, annual influenza vaccination is globally recommended. Nevertheless, evidence regarding the impact of repeated vaccination to ... Martin MA, Berg N, Koelle K. Influenza A genomic diversity during human infections underscores the strength of genetic drift and the existence of tight transmission bottlenecks. Virus Evol. 2024 Jun 1;10(1):veae042. Abstract
submitted by kickingbird at Jun, 18, 2024 from Virus Evol. 2024 Jun 1;10(1):veae042 (via https://academic.oup.com/ve/article/10/1/veae042/7686346)
Influenza infections result in considerable public health and economic impacts each year. One of the contributing factors to the high annual incidence of human influenza is the virus's ability to evade ... Ciacci Zanella G, Snyder CA, Arruda BL, Whitworth. Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with influenza A virus. Front Genome Ed. 2024 May 31;5:1320180. Abstract
submitted by kickingbird at Jun, 18, 2024 from Front Genome Ed. 2024 May 31;5:1320180 (via https://www.frontiersin.org/articles/10.3389/fgeed.2023.1320)
Influenza A virus (IAV) infection is initiated by hemagglutinin (HA), a glycoprotein exposed on the virion's lipid envelope that undergoes cleavage by host cell proteases to ensure membrane fusion, entry ... Rivetti AV Jr, Reischak D, de Oliveira CHS, Otaka. Phylodynamics of Avian Influenza A(H5N1) Viruses from Outbreaks in Brazil. Virus Res . 2024 Jun 14:199415.. Abstract
submitted by kickingbird at Jun, 17, 2024 from Virus Res . 2024 Jun 14:199415. (via https://pubmed.ncbi.nlm.nih.gov/38880334/)
Our study identified strains of the A/H5N1 virus in analyzed samples of subsistence poultry, wild birds, and mammals, belonging to clade 2.3.4.4b, genotype B3.2, with very high genetic similarity to strains ... Kang M, Wang LF, Sun BW, Wan WB, Ji X, Baele G, Bi. Zoonotic infections by avian influenza virus: changing global epidemiology, investigation, and control. Lancet Infect Dis. 2024 Jun 12:S1473-3099(24)00234. Abstract
submitted by kickingbird at Jun, 17, 2024 from Lancet Infect Dis. 2024 Jun 12:S1473-3099(24)00234 (via https://www.thelancet.com/journals/laninf/article/PIIS1473-3)
Avian influenza virus continues to pose zoonotic, epizootic, and pandemic threats worldwide, as exemplified by the 2020-23 epizootics of re-emerging H5 genotype avian influenza viruses among birds and ... 8128 items, 20/Page, Page[25/407][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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