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Gambaryan AS, Matrosovich TY, Boravleva EY, Lomaki. Receptor-binding properties of influenza viruses isolated from gulls. Virology 2018;522:37-45.  Abstract  
submitted by kickingbird at Jul, 23, 2018 from Virology 2018;522:37-45 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30014856/)
Ducks, gulls and shorebirds represent the major hosts of influenza A viruses (IAVs) in nature, but distinctions of IAVs in different birds are not well defined. Here we characterized the receptor specificity ...

Hatta Y, Boltz D, Sarawar S, Kawaoka Y, et al. Novel influenza vaccine M2SR protects against drifted H1N1 and H3N2 influenza virus challenge in ferrets with pre-existing immunity. Vaccine 2018 Jul 12..  Abstract  
submitted by kickingbird at Jul, 23, 2018 from Vaccine 2018 Jul 12. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30007825/)
Current influenza vaccines do not provide effective protection against heterologous influenza viruses. The ability of the novel M2SR influenza vaccine to protect against drifted influenza viruses was evaluated ...

Zhang L, Pan Y, Hackert V, van der Hoek W, et al.. The 2015-2016 influenza epidemic in Beijing, China: Unlike elsewhere, circulation of influenza A(H3N2) with moderate vaccine effectiveness. Vaccine 2018 Jul 14.  Abstract  
submitted by kickingbird at Jul, 23, 2018 from Vaccine 2018 Jul 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30017144/)
BACKGROUND: While the 2015-2016 influenza season in the northern hemisphere was dominated by A(H1N1)pdm09 and B/Victoria viruses, in Beijing, China, there was also significant circulation of influenza ...

Lin X, Noel JK, Wang Q, Ma J, et al. Atomistic simulations indicate the functional loop-to-coiled-coil transition in influenza hemagglutinin is not downhill. Proc Natl Acad Sci U S A 2018 Jul 16..  Abstract  
submitted by kickingbird at Jul, 23, 2018 from Proc Natl Acad Sci U S A 2018 Jul 16. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30012616/)
Influenza hemagglutinin (HA) mediates viral entry into host cells through a large-scale conformational rearrangement at low pH that leads to fusion of the viral and endosomal membranes. Crystallographic ...

Nogales A, Martinez-Sobrido L, Chiem K, Topham DJ,. FUNCTIONAL EVOLUTION OF THE 2009 PANDEMIC H1N1 INFLUENZA NS1 AND PA IN HUMANS. J Virol 2018 Jul 18.  Abstract  
submitted by kickingbird at Jul, 23, 2018 from J Virol 2018 Jul 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30021892/)
In 2009, an H1N1 influenza A virus (IAV, pH1N1) emerged in the human population from swine causing a pandemic. Importantly, this virus is still circulating in humans seasonally. To analyze the evolution ...

Huang QS, Bandaranayake D, Wood T, Newbern EC, et. Risk factors and attack rates of seasonal influenza infection: results of the SHIVERS seroepidemiologic cohort study. J Infect Dis 2018 Jul 17.  Abstract  
submitted by kickingbird at Jul, 23, 2018 from J Infect Dis 2018 Jul 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30016464/)
Background: Understanding the attack rate of influenza infection and the proportion who become ill by risk group is key to implementing prevention measures. While population-based studies of anti-haemagglutinin ...

Hickman HD, Mays JW, Gibbs J, Kosik I, et al. Influenza A Virus Negative Strand RNA Is Translated for CD8+ T Cell Immunosurveillance. Immunol 2018 Jul 16..  Abstract  
submitted by kickingbird at Jul, 23, 2018 from Immunol 2018 Jul 16. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30012850/)
Probing the limits of CD8+ T cell immunosurveillance, we inserted the SIINFEKL peptide into influenza A virus (IAV)-negative strand gene segments. Although IAV genomic RNA is considered noncoding, there ...

Furuyama Y, Takahashi Y, Noguchi K, Murakami H, et. Subpopulation Primers Essential for Exhaustive Detection of Diverse Hemagglutinin Genes of H5-Subtype Avian Influenza Viruses by Loop-mediated Isothermal Amplification Method. J Clin Microbiol 2018 Jul 18.  Abstract  
submitted by kickingbird at Jul, 23, 2018 from J Clin Microbiol 2018 Jul 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30021821/)
Loop-mediated isothermal amplification (LAMP) is a potential screening test for avian influenza (AI), but its narrow detection spectrum hinders the field of applications. To improve this narrow detection ...

Sant S, etc.,al. Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection. Front Immunol. 2018 Jun 27;9:1453.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Front Immunol. 2018 Jun 27;9:1453 (via https://www.ncbi.nlm.nih.gov/pubmed/29997621)
CD8+ T cells recognizing antigenic peptides derived from conserved internal viral proteins confer broad protection against distinct influenza viruses. As memory CD8+ T cells change throughout the human ...

Kuchar E, etc.,al. Knowledge Regarding Influenza and Influenza Vaccination in General Population: Results of a National Survey in Poland. Adv Exp Med Biol. 2018 Jul 12..  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Adv Exp Med Biol. 2018 Jul 12. (via https://www.ncbi.nlm.nih.gov/pubmed/29995213)
For the past 10 years, influenza vaccination coverage rate in Poland remains at a low 3% threshold. This low rate may be related to the unsatisfactory knowledge of vaccination, influenza, and misperception ...

de Lusignan S, etc.,al. Enhanced Safety Surveillance of Seasonal Quadrivalent Influenza Vaccines in English Primary Care: Interim Analysis. Adv Ther. 2018 Jul 11..  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Adv Ther. 2018 Jul 11. (via https://www.ncbi.nlm.nih.gov/pubmed/29995300)
INTRODUCTION: The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced safety surveillance (ESS) of seasonal influenza vaccines including a near real-time evaluation of collected ...

Ye C, etc.,al. Low coverage rate and awareness of influenza vaccine among older people in Shanghai, China: a cross-sectional study. Hum Vaccin Immunother. 2018 Jul 11:1-26.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Hum Vaccin Immunother. 2018 Jul 11:1-26 (via https://www.ncbi.nlm.nih.gov/pubmed/29995561)
BACKGROUND: Older individuals are at high risk for morbidity and mortality due to influenza, and the most effective way to prevent influenza is yearly vaccination. In China, the influenza vaccine is not ...

Tsai CP, Tsai HJ. Influenza B Viruses in Pigs, Taiwan. Influenza Other Respir Viruses. 2018 Jul 11.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Influenza Other Respir Viruses. 2018 Jul 11 (via https://www.ncbi.nlm.nih.gov/pubmed/29996007)
BACKGROUND: Influenza B viruses (IBVs) have never been isolated from natural-infected pigs in clinical cases, although the susceptibility of domestic pigs to experimental IBV infections had been confirmed ...

Yu WQ, etc.,al. Analysis of 15 cases of avian influenza virus (H7N9) infection. Zhonghua Jie He He Hu Xi Za Zhi. 2018 Jul 12;41(7).  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Zhonghua Jie He He Hu Xi Za Zhi. 2018 Jul 12;41(7) (via https://www.ncbi.nlm.nih.gov/pubmed/29996349)
Objective: To describe the clinical, chest imaging, pathological manifestations and therapeutic experience of human infection with A/H7N9 virus. Methods: The features of 15 laboratory-confirmed cases of ...

Ng YP, Yip TF, Peiris JSM, Ip NY, Lee SMY. Avian influenza A H7N9 virus infects human astrocytes and neuronal cells and induces inflammatory immune responses. J Neurovirol. 2018 Jul 9.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from J Neurovirol. 2018 Jul 9 (via https://www.ncbi.nlm.nih.gov/pubmed/29987581)
Seasonal, pandemic, and avian influenza virus infections may be associated with central nervous system pathology, albeit with varying frequency and different mechanisms. Here, we demonstrate that differentiated ...

Adlhoch C, Dabrera G, Penttinen P, Pebody R; Count. Protective Measures for Humans against Avian Influenza A(H5N8) Outbreaks in 22 European Union/European Economic Area Countries and Israel, 2016-17. Emerg Infect Dis. 2018 Oct 17;24(10)..  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Emerg Infect Dis. 2018 Oct 17;24(10). (via https://www.ncbi.nlm.nih.gov/pubmed/29989531)
We sought to better understand national approaches for managing potential human health risks during outbreaks of infection with avian influenza A(H5N8) virus during 2017-17. Twenty-three countries in the ...

Seiler P, etc.,al. H9N2 influenza viruses from Bangladesh: transmission in chicken and New World quail. Influenza Other Respir Viruses. 2018 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Influenza Other Respir Viruses. 2018 Jul 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29989679)
The H9N2 influenza viruses that have become established in Bangladeshi live poultry markets possess five gene segments of the highly pathogenic H7N3 avian influenza virus. We assessed the replication, ...

Hirotsu N, Saisho Y, Hasegawa T. The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: a prospective, observational study. Influenza Other Respir Viruses. 2018 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Influenza Other Respir Viruses. 2018 Jul 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29989680)
BACKGROUND: The relative ability of neuraminidase inhibitors (NAIs) to reduce household influenza transmission when given to index patients is not established.OBJECTIVES: To compare daily secondary infection ...

Schr?der T. etc.,al. The clinically approved MEK inhibitor Trametinib efficiently blocks influenza A virus propagation and cytokine expression. Antiviral Res. 2018 Jul 7;157:80-92.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Antiviral Res. 2018 Jul 7;157:80-92 (via https://www.ncbi.nlm.nih.gov/pubmed/29990517)
Influenza A virus (IAV) infections are still a major global threat for humans, especially for the risk groups of young children and the elderly. Annual epidemics and sporadically occurring pandemics highlight ...

He Z, Tao H. Epidemiology and ARIMA Model of Positive-Rate of Influenza Viruses among Children in Wuhan, China: A Nine-Year Retrospective Study. Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3 (via https://www.ncbi.nlm.nih.gov/pubmed/29990540)
OBJECTIVE: Influenza is a common childhood disease and protecting children by predicting the positive rate of influenza virus is important as vaccines are not routinely administered in China. Our study ...

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