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2024-7-17 3:49:57
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de Vos CJ, Elbers ARW. Quantitative Risk Assessment of Wind-Supported Transmission of Highly Pathogenic Avian Influenza Virus to Dutch Poultry Farms via Fecal Particles from Infected Wild Birds in the Environment. Pathogens. 2024; 13(7):571.  Abstract  
submitted by kickingbird at 2 days ago from Pathogens. 2024; 13(7):571 (via https://www.mdpi.com/2076-0817/13/7/571)
A quantitative microbial risk assessment model was developed to estimate the probability that the aerosolization of fecal droppings from wild birds in the vicinity of poultry farms would result in the ...

Zhao Y, Han L, Sang H, Liu S, Yang P, Hou Y, Xiao. Swine Influenza Viruses Isolated from 2019 to 2022 in Shandong Province, China, Exemplify the Dominant Genotype. Genes. 2024; 15(7):849.  Abstract  
submitted by kickingbird at 2 days ago from Genes. 2024; 15(7):849 (via https://www.mdpi.com/2073-4425/15/7/849)
Swine influenza viruses (SIVs) have been circulating in swine globally and are potential threats to human health. During the surveillance of SIVs in Shandong Province, China, from 2019 to 2022, 21 reassortant ...

Graaf-Rau A, Schmies K, Breithaupt A, Ciminski K,. Reassortment incompetent live attenuated and replicon influenza vaccines provide improved protection against influenza in piglets. NPJ Vaccines. 2024 Jul 13;9(1):127.  Abstract  
submitted by kickingbird at 2 days ago from NPJ Vaccines. 2024 Jul 13;9(1):127 (via https://www.nature.com/articles/s41541-024-00916-x)
Swine influenza A viruses (swIAV) cause an economically important respiratory disease in modern pig production. Continuous virus transmission and antigenic drift are difficult to control in enzootically ...

Chen D, Su W, Choy KT, Chu YS, Lin CH, Yen HL. High throughput profiling identified PA-L106R amino acid substitution in A(H1N1)pdm09 influenza virus that confers reduced susceptibility to baloxavir in vitro. Antiviral Res. 2024 Jul 11:105961.  Abstract  
submitted by kickingbird at 2 days ago from Antiviral Res. 2024 Jul 11:105961 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Baloxavir acid (BXA) is a pan-influenza antiviral that targets the cap-dependent endonuclease of the polymerase acidic (PA) protein required for viral mRNA synthesis. To gain a comprehensive understanding ...

Zeng Z, Li Q, Guo H, Liu Y, Liang L, Lai Y, Fang Y. Modified transport medium for improving influenza virus detection. Front. Cell. Infect. Microbiol. 14:1399782.  Abstract  
submitted by kickingbird at 2 days ago from Front. Cell. Infect. Microbiol. 14:1399782 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Background: Accurate detection of influenza virus in clinical samples requires correct execution of all aspects of the detection test. If the viral load in a sample is below the detection limit, a false ...

Fan Q, Xie Z, Zhao J, Hua J, Wei Y, Li X, Li D, Lu. Simultaneous differential detection of H5, H7 and H9 subtypes of avian influenza viruses by a triplex fluorescence loop-mediated isothermal amplification assay. Front. Vet. Sci. 11:1419312.  Abstract  
submitted by kickingbird at 2 days ago from Front. Vet. Sci. 11:1419312 (via https://www.frontiersin.org/journals/veterinary-science/arti)
H5, H7, and H9 are pivotal avian influenza virus (AIV) subtypes that cause substantial economic losses and pose potential threats to public health worldwide. In this study, a novel triplex fluorescence ...

Gu C, Chen Y, Li H, Wang J, Liu S. Considerations when treating influenza infections with oseltamivir. Expert Opin Pharmacother. 2024 Jul 12.  Abstract  
submitted by kickingbird at 3 days ago from Expert Opin Pharmacother. 2024 Jul 12 (via https://www.tandfonline.com/doi/full/10.1080/14656566.2024.2)
Introduction: Since the coronavirus disease 2019-mandated social distancing policy has been lifted worldwide, the circulation of influenza is expected to resume. Currently, oseltamivir is approved as the ...

Andreev K, Jones JC, Seiler P, Kandeil A, Webby RJ. Genotypic and phenotypic susceptibility of emerging avian influenza A viruses to neuraminidase and cap-dependent endonuclease inhibitors. Antiviral Res. 2024 Jul 8:105959.  Abstract  
submitted by kickingbird at 5 days ago from Antiviral Res. 2024 Jul 8:105959 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Avian influenza outbreaks, including ones caused by highly pathogenic A(H5N1) clade 2.3.4.4b viruses, have devastated animal populations and remain a threat to humans. Risk elements assessed for emerging ...

Ahrens AK, Pohlmann A, Grund C, Harder T, Beer M. Novel Genotypes of Highly Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b Viruses, Germany, November 2023. Emerg Infect Dis. 2024 Aug.  Abstract  
submitted by kickingbird at 5 days ago from Emerg Infect Dis. 2024 Aug (via https://wwwnc.cdc.gov/eid/article/30/8/24-0103_article)
Several subtypes and many different genotypes of highly pathogenic avian influenza viruses of subtype H5 clade 2.3.4.4b have repeatedly caused outbreaks in Germany. Four new highly pathogenic avian influenza ...

Sahoo MK, Morante IEA, Huang C, Solis D, Yamamoto. Multiplex Dual-Target Reverse Transcription PCR for Subtyping Avian Influenza A(H5) Virus. Emerg Infect Dis. 2024 Aug.  Abstract  
submitted by kickingbird at 5 days ago from Emerg Infect Dis. 2024 Aug (via https://wwwnc.cdc.gov/eid/article/30/8/24-0785_article)
An increased risk for human infection with avian influenza A(H5N1) viruses is of concern. We developed an internally controlled, dual-target reverse transcription PCR for influenza A(H5) subtyping. This ...

Zhou Y, Chen W, Wang G, Lei Z, Zhang M, Li Y. A label-free H1N1 influenza virus immunosensor based on an N-LIG/Au laser induced graphene microelectrode. Anal Methods. 2024 Jul 11.  Abstract  
submitted by kickingbird at 5 days ago from Anal Methods. 2024 Jul 11 (via https://pubs.rsc.org/en/content/articlelanding/2024/ay/d4ay0)
A label-free immunosensor based on an N-doped laser direct graphene (N-LIG)/Au electrode was proposed for H1N1 influenza virus detection. By utilizing the instantaneous high temperature of laser irradiation, ...

Stiles P, Grant M, Kim H, Comin A, Svensson M, Nil. Mapping the risk of introduction of highly pathogenic avian influenza to Swedish poultry. Prev Vet Med. 2024 Jun 29;230:106260.  Abstract  
submitted by kickingbird at 7 days ago from Prev Vet Med. 2024 Jun 29;230:106260 (via https://www.sciencedirect.com/science/article/pii/S016758772)
Outbreaks of highly pathogenic avian influenza (HPAI) have resulted in severe economic impact for national governments and poultry industries globally and in Sweden in recent years. Veterinary authorities ...

Yin S, Xu C, Zhang Y, de Boer WF, Mundkur T, Artoi. Strong and consistent effects of waterbird composition on HPAI H5 occurrences across Europe. Ecol Appl. 2024 Jul 8:e3010.  Abstract  
submitted by kickingbird at 7 days ago from Ecol Appl. 2024 Jul 8:e3010 (via https://esajournals.onlinelibrary.wiley.com/doi/10.1002/eap.)
Since 2014, highly pathogenic avian influenza (HPAI) H5 viruses of clade 2.3.4.4 have been dominating the outbreaks across Europe, causing massive deaths among poultry and wild birds. However, the factors ...

Dai J, Zhao J, Xia J, Zhang P, Ding Y, Li Q, Hou M. Phylogenetic and mutational analysis of H10N3 avian influenza A virus in China: potential threats to human health. Front Cell Infect Microbiol. 2024 Jun 24;14:14336.  Abstract  
submitted by kickingbird at 7 days ago from Front Cell Infect Microbiol. 2024 Jun 24;14:14336 (via https://www.frontiersin.org/journals/cellular-and-infection-)
In recent years, the avian influenza virus has emerged as a significant threat to both human and public health. This study focuses on a patient infected with the H10N3 subtype of avian influenza virus, ...

James J, Thomas SS, Seekings AH, Mahmood S, Kelly. Evaluating the epizootic and zoonotic threat of an H7N9 low-pathogenicity avian influenza virus (LPAIV) variant associated with enhanced pathogenicity in turkeys. J Gen Virol. 2024 Jul;105(7).  Abstract  
submitted by kickingbird at 7 days ago from J Gen Virol. 2024 Jul;105(7) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Between 2013 and 2017, the A/Anhui/1/13-lineage (H7N9) low-pathogenicity avian influenza virus (LPAIV) was epizootic in chickens in China, causing mild disease, with 616 fatal human cases. Despite poultry ...

Yang Q, Ji J, Yang J, Zhang Y, Yin H, Dai H, Wang. Diversity of genotypes and pathogenicity of H9N2 avian influenza virus derived from wild bird and domestic poultry. Front. Microbiol. 15:1402235.  Abstract  
submitted by kickingbird at 8 days ago from Front. Microbiol. 15:1402235 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Introduction: The H9N2 subtype is a predominant avian influenza virus (AIV) circulating in Chinese poultry, forming various genotypes (A-W) based on gene segment origins. This study aims to investigate ...

Eisfeld AJ, Biswas A, Guan L, Gu C, Maemura T, Tri. Pathogenicity and transmissibility of bovine H5N1 influenza virus. Nature. 2024 Jul 8.  Abstract  
submitted by kickingbird at 8 days ago from Nature. 2024 Jul 8 (via https://www.nature.com/articles/s41586-024-07766-6)
Highly pathogenic H5N1 avian influenza (HPAI H5N1) viruses occasionally infect, but typically do not transmit, in mammals. In the Spring of 2024, an unprecedented outbreak of HPAI H5N1 in bovine herds ...

Yuxin Guo, etc.,al. [preprint]An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts. https://doi.org/10.1101/2024.07.03.601996.  Abstract  
submitted by kickingbird at 8 days ago from https://doi.org/10.1101/2024.07.03.601996 (via https://www.biorxiv.org/content/10.1101/2024.07.03.601996v2)
Alterations in the PB2-627 domain could substantially increase the risk of an avian influenza virus (AIV) pandemic. So far, a well-known mammalian mutation PB2-E627K has not been maintained in AIV in poultry, ...

Wang X, Tang XE, Zheng H, Gao R, Lu X, Yang W, Zho. Amino acid mutations PB1-V719M and PA-N444D combined with PB2-627K contribute to the pathogenicity of H7N9 in mice. Vet Res. 2024 Jul 5;55(1):86.  Abstract  
submitted by kickingbird at 9 days ago from Vet Res. 2024 Jul 5;55(1):86 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
H7N9 subtype avian influenza viruses (AIVs) cause 1567 human infections and have high mortality, posing a significant threat to public health. Previously, we reported that two avian-derived H7N9 isolates ...

Adam S. Lauring, etc.,al. [preprint]Surveillance of H5 HPAI in Michigan using retail milk. https://doi.org/10.1101/2024.07.04.602115.  Abstract  
submitted by kickingbird at 9 days ago from https://doi.org/10.1101/2024.07.04.602115 (via https://www.biorxiv.org/content/10.1101/2024.07.04.602115v1)
An outbreak of highly pathogenic avian influenza virus (HPAI) H5N1 in dairy cattle in the United States has spread to at least 136 dairy herds in 11 states. Due to a lack of testing, it has been difficult ...

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