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Zhang Y, Yakob L, Bonsall MB, Hu W. Predicting seasonal influenza epidemics using cross-hemisphere influenza surveillance data and local internet query data. Sci Rep. 2019 Mar 1;9(1):3262..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Sci Rep. 2019 Mar 1;9(1):3262. (via https://www.nature.com/articles/s41598-019-39871-2)
Can early warning systems be developed to predict influenza epidemics? Using Australian influenza surveillance and local internet search query data, this study investigated whether seasonal influenza epidemics ...

Umut Karakus, et al. MHC class II proteins mediate cross-species entry of bat influenza viruses. Nature 20 Feb, 2019.  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Nature 20 Feb, 2019 (via https://www.nature.com/articles/s41586-019-0955-3)
Zoonotic influenza A viruses of avian origin can cause severe disease in individuals, or even global pandemics, and thus pose a threat to human populations. Waterfowl and shorebirds are believed to be ...

Barnes B, et al. Modelling high pathogenic avian influenza outbreaks in the commercial poultry industry. Theor Popul Biol. 2019 Feb 27..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Theor Popul Biol. 2019 Feb 27. (via https://www.sciencedirect.com/science/article/pii/S004058091)
Highly pathogenic avian influenza (HPAI) outbreaks are devastating to poultry industries and pose a risk to human health. There is concern that demand for free-range poultry products could increase the ...

Lim KS, et al. Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy. Biochim Biophys Acta Gen Subj. 2019 Feb 27..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Biochim Biophys Acta Gen Subj. 2019 Feb 27. (via https://www.sciencedirect.com/science/article/pii/S030441651)
BACKGROUND: Hemagglutinin (HA) of influenza A is one of the key virulence factors that mediates the release of viral components in host cells. HA is initially synthesized as a trimeric precursor (HA0) ...

Paulino J, Pang X, Hung I, Zhou HX, Cross TA. Influenza A M2 Channel Clustering at High Protein/Lipid Ratios: Viral Budding Implications. Biophys J. 2019 Feb 10.  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Biophys J. 2019 Feb 10 (via https://www.cell.com/biophysj/fulltext/S0006-3495(19)30114-6)
Protein dynamics in crowded environments is important for understanding protein functions in vivo and is especially relevant for membrane proteins because of the roles of protein-protein interactions in ...

Lalueza A, et al. Influence of viral load in the outcome of hospitalized patients with influenza virus infection. Eur J Clin Microbiol Infect Dis. 2019 Feb 28..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Eur J Clin Microbiol Infect Dis. 2019 Feb 28. (via https://link.springer.com/article/10.1007%2Fs10096-019-03514)
The role of viral load in the outcome of patients requiring hospital admission due to influenza is not well established. We aim to assess if there is an association between the viral load and the outcome ...

Shepardson K, et al. A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections. Viral Immunol. 2019 Mar 1..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Viral Immunol. 2019 Mar 1. (via https://www.liebertpub.com/doi/10.1089/vim.2018.0118)
Influenza A viruses (IAVs) have multiple mechanisms for altering the host immune response to aid in virus survival and propagation. While both type I and II interferons (IFNs) have been associated with ...

Hasan M, et al. Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virus. Microb Pathog. 2019 Feb 26.  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Microb Pathog. 2019 Feb 26 (via https://www.sciencedirect.com/science/article/pii/S088240101)
H7N9, a novel strain of avian origin influenza was the first recorded incidence where a human was transited by a N9 type influenza virus. Effective vaccination against influenza A (H7N9) is a major concern, ...

Pei S, Cane MA, Shaman J. Predictability in process-based ensemble forecast of influenza. PLoS Comput Biol. 2019 Feb 28;15(2):e1006783.  Abstract  
submitted by kickingbird at Mar, 2, 2019 from PLoS Comput Biol. 2019 Feb 28;15(2):e1006783 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Process-based models have been used to simulate and forecast a number of nonlinear dynamical systems, including influenza and other infectious diseases. In this work, we evaluate the effects of model initial ...

Naguib MM, et al. Avian influenza viruses at the wild-domestic bird interface in Egypt. Infect Ecol Epidemiol. 2019 Feb 20;9(1):1575687..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Infect Ecol Epidemiol. 2019 Feb 20;9(1):1575687. (via https://www.tandfonline.com/doi/full/10.1080/20008686.2019.1)
Wild birds of the orders Anseriformes (mainly ducks, geese and swans) and Charadriiformes (mainly gulls, terns and waders) constitute the natural reservoir for low pathogenic avian influenza (LPAI) viruses. ...

Zeng H, et al. Tropism and Infectivity of a Seasonal A(H1N1) and a Highly Pathogenic Avian A(H5N1) Influenza Virus in Primary Differentiated Ferret Nasal Epithelial Cell Cultures. J Virol. 2019 Feb 27..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27. (via https://jvi.asm.org/content/early/2019/02/22/JVI.00080-19)
Ferrets represent an invaluable animal model to study influenza virus pathogenesis and transmission. To further characterize this model, we developed a differentiated primary ferret nasal epithelial cell ...

Tang YS, Lo CY, Mok CK, Chan PK, Shaw PC. The extended C-terminal region of influenza C nucleoprotein is important for nuclear import and RNP activity. J Virol. 2019 Feb 27.  Abstract  
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27 (via https://jvi.asm.org/content/early/2019/02/22/JVI.02048-18)
The influenza C virus (ICV) is a human pathogenic agent and the infections are frequently identified in children. Compared to influenza A and B viruses, the nucleoprotein of ICV (NPC) has an extended C-terminal ...

Lu Y, et al. In Vivo Characterization of Avian Influenza A (H5N1) and (H7N9) Viruses Isolated from Canadian Travelers. Viruses. 2019 Feb 23;11(2)..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 23;11(2). (via https://www.mdpi.com/1999-4915/11/2/193)
Highly pathogenic avian influenza (HPAI) H5N1 and low pathogenic avian influenza (LPAI) H7N9 viruses pose a severe threat to public health through zoonotic infection, causing severe respiratory disease ...

Blanco-Lobo P, Nogales A, Rodríguez L, etc al. Novel Approaches for The Development of Live Attenuated Influenza Vaccines. Viruses. 2019 Feb 22;11(2)..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 22;11(2). (via https://www.mdpi.com/1999-4915/11/2/190)
Influenza virus still represents a considerable threat to global public health, despite the advances in the development and wide use of influenza vaccines. Vaccination with traditional inactivate influenza ...

Li Z, Fu J, Lin G, Jiang D. Spatiotemporal Variation and Hotspot Detection of the Avian Influenza A(H7N9) Virus in China, 2013~2017. Int J Environ Res Public Health. 2019 Feb 22;16(4).  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Int J Environ Res Public Health. 2019 Feb 22;16(4) (via https://www.mdpi.com/1660-4601/16/4/648)
This study aims to describe the spatial and temporal characteristics of human infections with H7N9 virus in China using data from 19 February 2013 to 30 September 2017 extracted from Centre for Health ...

Kissling E, et al. Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019. Euro Surveill. 2019 Feb;24(8)..  Abstract  
submitted by kickingbird at Feb, 28, 2019 from Euro Surveill. 2019 Feb;24(8). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Influenza A(H1N1)pdm09 and A(H3N2) viruses both circulated in Europe in October 2018-January 2019. Interim results from six studies indicate that 2018/19 influenza vaccine effectiveness (VE) estimates ...

Corbett KS, et al. Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages. MBio. 2019 Feb 26;10(1)..  Abstract  
submitted by kickingbird at Feb, 28, 2019 from MBio. 2019 Feb 26;10(1). (via https://mbio.asm.org/content/10/1/e02810-18)
Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by ...

Kramer SC, Shaman J. Development and validation of influenza forecasting for 64 temperate and tropical countries. PLoS Comput Biol. 2019 Feb 27;15(2):e1006742..  Abstract  
submitted by kickingbird at Feb, 28, 2019 from PLoS Comput Biol. 2019 Feb 27;15(2):e1006742. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Accurate forecasts of influenza incidence can be used to inform medical and public health decision-making and response efforts. However, forecasting systems are uncommon in most countries, with a few notable ...

Farsakoglu Y, et al. Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner. Cell Rep. 2019 Feb 26;26(9):2307-2315.e5.  Abstract  
submitted by kickingbird at Feb, 28, 2019 from Cell Rep. 2019 Feb 26;26(9):2307-2315.e5 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)301)
The role of natural killer (NK) cells in the immune response against vaccines is not fully understood. Here, we examine the function of infiltrated NK cells in the initiation of the inflammatory response ...

Klifa R, et al. Influenza vaccination among children with idiopathic nephrotic syndrome: an investigation of practices. BMC Nephrol. 2019 Feb 25;20(1):65..  Abstract  
submitted by kickingbird at Feb, 27, 2019 from BMC Nephrol. 2019 Feb 25;20(1):65. (via https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882)
BACKGROUND: Annual influenza vaccination is recommended for all children with idiopathic nephrotic syndrome (INS) in France. Consequently, the Social Security automatically sends prescriptions to all patients ...

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