Jiang Z, Wei F, Zhang Y, Wang T, Gao W, Yu S, Sun. IFI16 directly senses viral RNA and enhances RIG-I transcription and activation to restrict influenza virus infection. Nat Microbiol. 2021 May 13. Abstract
submitted by kickingbird at May, 17, 2021 from Nat Microbiol. 2021 May 13 (via https://www.nature.com/articles/s41564-021-00907-x)
The retinoic acid-inducible gene I (RIG-I) receptor senses cytoplasmic viral RNA and activates type I interferons (IFN-I) and downstream antiviral immune responses. How RIG-I binds to viral RNA and how ... Powell H, Liu H, Pekosz A. Changes in sialic acid binding associated with egg adaptation decrease live attenuated influenza virus replication in human nasal epithelial cell cultures. Vaccine. 2021 May 10:S0264-410X(21)00535-1. Abstract
submitted by kickingbird at May, 17, 2021 from Vaccine. 2021 May 10:S0264-410X(21)00535-1 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Live Attenuated Influenza Virus (LAIV) is administered to and replicates in the sinonasal epithelium. Candidate LAIV vaccine strains are selected based on their ability to replicate to a high titer in ... Flórido M, Chiu J, Hogg PJ. Influenza A virus hemagglutinin is produced in different disulfide-bonded states. Antioxid Redox Signal. 2021 May 13. Abstract
submitted by kickingbird at May, 17, 2021 from Antioxid Redox Signal. 2021 May 13 (via https://www.liebertpub.com/doi/10.1089/ars.2021.0033)
Aims: Influenza A virus hemagglutinin (HA) binding to sialic acid on lung epithelial cells triggers membrane fusion and infection. Host thiol isomerases have been shown to play a role in Influenza A virus ... Li Y, Ma Y, An Z, Yue C, Wang Y, Liu Y, Yuan X, Zh. Immunogenicity of trivalent seasonal influenza vaccine in patients with chronic obstructive pulmonary disease. Hum Vaccin Immunother. 2021 May 13:1-6. Abstract
submitted by kickingbird at May, 17, 2021 from Hum Vaccin Immunother. 2021 May 13:1-6 (via https://www.tandfonline.com/doi/abs/10.1080/21645515.2021.19)
Objective: Current evidence on the immunogenicity of influenza vaccination in patients with chronic obstructive pulmonary disease (COPD) is limited. To address this need for additional knowledge, we conducted ... Okda FA, Perry SS, Webby RJ, Russell CJ. Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model. PLoS One. 2021 May 12;16(5):e0251473. Abstract
submitted by kickingbird at May, 14, 2021 from PLoS One. 2021 May 12;16(5):e0251473 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different ... Hara H, Chida J, Uchiyama K, Pasiana AD, Takahashi. Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells. Sci Rep. 2021 May 12;11(1):10109. Abstract
submitted by kickingbird at May, 14, 2021 from Sci Rep. 2021 May 12;11(1):10109 (via https://www.nature.com/articles/s41598-021-89586-6)
Misfolding of the cellular prion protein, PrPC, into the amyloidogenic isoform, PrPSc, which forms infectious protein aggregates, the so-called prions, is a key pathogenic event in prion diseases. No pathogens ... Okda FA, Perry SS, Webby RJ, Russell CJ. Interplay between H1N1 influenza a virus infection, extracellular and intracellular respiratory tract pH, and host responses in a mouse model. PLoS One. 2021 May 12;16(5):e0251473. Abstract
submitted by kickingbird at May, 13, 2021 from PLoS One. 2021 May 12;16(5):e0251473 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
During influenza A virus (IAV) entry, the hemagglutinin (HA) protein is triggered by endosomal low pH to undergo irreversible structural changes that mediate membrane fusion. HA proteins from different ... Overeem NJ, Hamming PHE, Tieke M, van der Vries E,. Multivalent Affinity Profiling: Direct Visualization of the Superselective Binding of Influenza Viruses. ACS Nano. 2021 May 12. Abstract
submitted by kickingbird at May, 13, 2021 from ACS Nano. 2021 May 12 (via https://pubs.acs.org/doi/10.1021/acsnano.1c00166)
The influenza A virus (IAV) interacts with the glycocalyx of host cells through its surface proteins hemagglutinin (HA) and neuraminidase (NA). Quantitative biophysical measurements of these interactions ... Oltean T, Van San E, Divert T, Vanden Berghe T, Sa. Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL. Cell Death Dis. 2021 May 11;12(5):471. Abstract
submitted by kickingbird at May, 13, 2021 from Cell Death Dis. 2021 May 11;12(5):471 (via https://www.nature.com/articles/s41419-021-03746-0)
RIPK3 was reported to play an important role in the protection against influenza A virus (IAV) in vivo. Here we show that the requirement of RIPK3 for protection against IAV infection in vivo is only apparent ... Han J, Ganti K, Sali VK, Twigg C, Zhang Y, Manivas. Host factor Rab11a is critical for efficient assembly of influenza A virus genomic segments. PLoS Pathog. 2021 May 10;17(5):e1009517. Abstract
submitted by kickingbird at May, 11, 2021 from PLoS Pathog. 2021 May 10;17(5):e1009517 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
It is well documented that influenza A viruses selectively package 8 distinct viral ribonucleoprotein complexes (vRNPs) into each virion; however, the role of host factors in genome assembly is not completely ... Wang Q, Zhang Q, Zheng M, Wen J, Li Q, Zhao G. Viral-Host Interactome Analysis Reveals Chicken STAU2 Interacts With Non-structural Protein 1 and Promotes the Replication of H5N1 Avian Influenza Virus. Front Immunol. 2021 Apr 21;12:590679. Abstract
submitted by kickingbird at May, 11, 2021 from Front Immunol. 2021 Apr 21;12:590679 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.5906)
As a highly pathogenic influenza virus, H5N1 avian influenza virus (AIV) poses a great threat to poultry production and public health. H5N1 AIV has a small genome and, therefore, relies heavily on its ... Fahim M, AbdElGawad B, Hassan H, Naguib A, Ahmed E. Epidemiology and outcome of influenza-associated infections among hospitalized patients with acute respiratory infections, Egypt national surveillance system, 2016-2019. Influenza Other Respir Viruses. 2021 May 7. Abstract
submitted by kickingbird at May, 8, 2021 from Influenza Other Respir Viruses. 2021 May 7 (via https://pubmed.ncbi.nlm.nih.gov/33960675/)
Introduction: Egypt has established different types of surveillance systems to monitor influenza activities, early detect outbreaks, and tailor efficient prevention and control strategies. This is the ... Bo H, Zhang Y, Dong LB, Dong J, Li XY, Zhao X, Li. Distribution of avian influenza viruses according to environmental surveillance during 2014-2018, China. Infect Dis Poverty. 2021 May 6;10(1):60. Abstract
submitted by kickingbird at May, 8, 2021 from Infect Dis Poverty. 2021 May 6;10(1):60 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: Recurrent infections of animal hosts with avian influenza viruses (AIVs) have posted a persistent threat. It is very important to understand the avian influenza virus distribution and characteristics ... Lee LY, Zhou J, Koszalka P, Frise R, Farrukee R, B. Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model. PLoS Pathog. 2021 May 6;17(5):e1009527. Abstract
submitted by kickingbird at May, 7, 2021 from PLoS Pathog. 2021 May 6;17(5):e1009527
Baloxavir is approved in several countries for the treatment of uncomplicated influenza in otherwise-healthy and high-risk patients. Treatment-emergent viruses with reduced susceptibility to baloxavir ... Su Z, Zhao G, Dou W. High-sensitivity detection of two H7 subtypes of avian influenza viruses (AIVs) by immunochromatographic assay with highly chromatic red silica nanoparticles. Anal Methods. 2021 May 6. Abstract
submitted by kickingbird at May, 7, 2021 from Anal Methods. 2021 May 6 (via https://pubs.rsc.org/en/content/articlelanding/2021/AY/D1AY0)
In this work, a sensitive and quantitative immunochromatographic assay (ICA) detection method for avian influenza viruses (AIVs) of the H7 hemagglutinin (HA) antigen was established based on highly chromatic ... Zhang N, Ma Y, Tian Y, Zhou Y, Tang Y, Hu S. Downregulation of microRNA?221 facilitates H1N1 influenza A virus replication through suppression of type?IFN response by targeting the SOCS1/NF?κB pathway. Mol Med Rep. 2021 Jul;24(1):497. Abstract
submitted by kickingbird at May, 7, 2021 from Mol Med Rep. 2021 Jul;24(1):497 (via https://www.spandidos-publications.com/10.3892/mmr.2021.1213)
Accumulating data has indicated that host microRNAs (miRNAs/miRs) play essential roles in innate immune responses to viral infection; however, the roles and the underlying mechanisms of miRNAs in influenza ... Golabi M, Flodrops M, Grasland B, Vinayaka AC, Quy. Development of Reverse Transcription Loop-Mediated Isothermal Amplification Assay for Rapid and On-Site Detection of Avian Influenza Virus. Front Cell Infect Microbiol. 2021 Apr 19;11:652048. Abstract
submitted by kickingbird at May, 7, 2021 from Front Cell Infect Microbiol. 2021 Apr 19;11:652048 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.6520)
Avian influenza virus (AIV) outbreaks occur frequently worldwide, causing a potential public health risk and great economic losses to poultry industries. Considering the high mutation rate and frequent ... Harrington WN, Kackos CM, Webby RJ. The evolution and future of influenza pandemic preparedness. Exp Mol Med. 2021 May 6. Abstract
submitted by kickingbird at May, 7, 2021 from Exp Mol Med. 2021 May 6 (via https://www.nature.com/articles/s12276-021-00603-0)
The influenza virus is a global threat to human health causing unpredictable yet recurring pandemics, the last four emerging over the course of a hundred years. As our knowledge of influenza virus evolution, ... Guinat C, Tago D, Corre T, Selinger C, Djidjou-Dem. Optimizing the early detection of low pathogenic avian influenza H7N9 virus in live bird markets. J R Soc Interface. 2021 May;18(178):20210074. Abstract
submitted by kickingbird at May, 6, 2021 from J R Soc Interface. 2021 May;18(178):20210074 (via https://royalsocietypublishing.org/doi/10.1098/rsif.2021.007)
In Southeast Asia, surveillance at live bird markets (LBMs) has been identified as crucial for detecting avian influenza viruses (AIV) and reducing the risk of human infections. However, the design of ... Nemoto M, Ohta M, Yamanaka T, Kambayashi Y, Bannai. Antigenic differences between equine influenza virus vaccine strains and Florida sublineage clade 1 strains isolated in Europe in 2019. Vet J. 2021 Jun;272:105674. Abstract
submitted by kickingbird at May, 6, 2021 from Vet J. 2021 Jun;272:105674 (via https://www.sciencedirect.com/science/article/abs/pii/S10900)
From late 2018 to 2019, equine influenza virus (EIV) strains of Florida sublineage clade 1 (Fc1), which had until then been circulating mainly in the United States, suddenly spread across Europe causing ... 8130 items, 20/Page, Page[120/407][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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