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2024-11-22 17:46:07
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Public Health Agency of Canada. Protocol for enhanced human surveillance of avian influenza A(H5N1) on farms in Canada. Public Health Agency of Canada.  Abstract  
submitted by kickingbird at 7 hours ago from Public Health Agency of Canada (via https://www.canada.ca/en/public-health/services/diseases/avi)
Globally, avian influenza A(H5N1) has been detected for several years in domestic birds. Rare zoonotic human cases have been reported, but, as of publishing, without evidence of human-to-human transmission. ...

Zhao X, Shen M, Cui L, Liu C, Yu J, Wang G, Erdelj. Evolutionary analysis of Hemagglutinin and neuraminidase gene variation in H1N1 swine influenza virus from vaccine intervention in China. Sci Rep. 2024 Nov 20;14(1):28792.  Abstract  
submitted by kickingbird at 8 hours ago from Sci Rep. 2024 Nov 20;14(1):28792 (via https://www.nature.com/articles/s41598-024-80457-4)
Influenza poses a significant threat to the global economy and health. Inactivated virus vaccines were introduced in China for prevention in 2018. In this study, three pairs of hemagglutinin (HA) and neuraminidase ...

Günther A, Krone O, Globig A, Pohlmann A, King J,. Avian raptors are indicator species and victims of high pathogenicity avian influenza virus HPAIV H5N1 (clade 2.3.4.4b) in Germany. Sci Rep. 2024 Nov 20;14(1):28779.  Abstract  
submitted by kickingbird at 8 hours ago from Sci Rep. 2024 Nov 20;14(1):28779 (via https://www.nature.com/articles/s41598-024-79930-x)
Transition of highly pathogenic clade 2.3.4.4b H5 avian influenza virus (HPAIV) from epizootic to enzootic status in Northern European countries was associated with severe losses and even mass mortalities ...

Seo YR, Lee SH, Jeong S, Cho H, Kim D, Kim DJ, Si. Genetic and pathological analysis of hooded cranes (Grus monacha) naturally infected with clade 2.3.4.4b highly pathogenic avian influenza H5N1 virus in South Korea in the winter of 2022. Front Vet Sci. 2024 Nov 6;11:1499440.  Abstract  
submitted by kickingbird at 8 hours ago from Front Vet Sci. 2024 Nov 6;11:1499440 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Highly pathogenic avian influenza (HPAI) subtype H5Nx viruses of the A/Goose/Guangdong/1/1996 (Gs/Gd) lineage have caused substantial economic losses in the poultry industry and represent a significant ...

Zhao Q, Zhang J, Yang S, Bai X, Li Y, Zhang W, Zha. H1N1 swine influenza viruses upregulate NEU1 expression through histone H3 acetylation regulated by HDAC2. Virology. 2024 Nov 15;601:110305.  Abstract  
submitted by kickingbird at 8 hours ago from Virology. 2024 Nov 15;601:110305 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Mammalian membrane sialic acid is the key receptor for influenza virus. Sialidases, the main type of enzyme that can hydrolyze membrane sialic acids in mammalian cells, have the potential to affect the ...

Kerry Goldin, etc.,al. [preprint]Enhanced encephalitic tropism of bovine H5N1 compared to the Vietnam H5N1 isolate in mice. https://doi.org/10.1101/2024.11.19.624162.  Abstract  
submitted by kickingbird at 9 hours ago from https://doi.org/10.1101/2024.11.19.624162 (via https://www.biorxiv.org/content/10.1101/2024.11.19.624162v2)
In recent years, the landscape of highly pathogenic avian influenza (HPAI) virus infections has shifted, as evidenced by an increase in infections among mammals. This includes the recent circulation of ...

Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang. Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 low pathogenicity avian influenza virus. Nat Commun. 2024 Nov 19;15(1):10012.  Abstract  
submitted by kickingbird at 1 days ago from Nat Commun. 2024 Nov 19;15(1):10012 (via https://www.nature.com/articles/s41467-024-54374-z)
The 1957 H2N2 influenza pandemic virus [A(H2N2)pdm1957] has disappeared from humans since 1968, while H2N2 avian influenza viruses (AIVs) are still circulating in birds. It is necessary to reveal the recurrence ...

Reid SM, Coward VJ, James J, Hansen RDE, Birch C,. Validation of a reduction in time for avian influenza virus isolation using specific pathogen-free embryonated chicken eggs. Vet Rec. 2024 Nov 19:e4842.  Abstract  
submitted by kickingbird at 1 days ago from Vet Rec. 2024 Nov 19:e4842 (via https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vetr)
Background: The international gold standard for avian influenza virus (AIV) diagnosis is virus isolation (VI) in specific pathogen-free embryonated chicken eggs (ECEs). AIV isolation typically involves ...

Vu TH, Kim C, Truong AD, Kim JM, Lillehoj HS, Hong. Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection. Poult Sci. 2024 Nov 6;104(1):104524.  Abstract  
submitted by kickingbird at 1 days ago from Poult Sci. 2024 Nov 6;104(1):104524 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) pose a significant threat to global poultry production, necessitating effective control strategies to mitigate economic losses and ensure animal welfare. Long non-coding ...

WHO. Influenza at the human-animal interface summary and assessment, 1 November 2024. WHO.  Abstract  
submitted by kickingbird at 1 days ago from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 28 September to 1 November 2024, the detection of influenza A(H5) virus in 30 humans and influenza A(H9N2) virus in one human were reported officially.? New human cases: From 28 September to 1 November ...

Marie-Cécile Dupas, etc.,al. [preprint]Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward. https://doi.org/10.1101/2024.11.15.623755.  Abstract  
submitted by kickingbird at 2 days ago from https://doi.org/10.1101/2024.11.15.623755 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623755v1)
Avian influenza (AI) is a highly contagious viral disease affecting poultry and wild water birds, posing significant global challenges due to its high mortality rates and economic impacts. Highly pathogenic ...

Akanbi OB, Alaka OO, Olaifa OS, Meseko CA, Inuwa B. Pathology and molecular detection of influenza A subtype H9N2 virus in commercial poultry in Nigeria, 2024. Open Vet J. 2024 Sep;14(9):2381-2391.  Abstract  
submitted by kickingbird at 2 days ago from Open Vet J. 2024 Sep;14(9):2381-2391 (via https://www.bibliomed.org/?mno=204059)
Background: After the first Avian Influenza H5N1 outbreak in Nigerian poultry in 2006, subsequent waves of outbreaks occurred, causing substantial losses. Despite effective control measures by 2008, a ...

Goto T, Kawai N, Bando T, Takasaki Y, Shindo S, Sa. Virological and Clinical Outcomes of Influenza Outpatients Treated With Baloxavir, Oseltamivir, or Laninamivir in the 2023-2024 Season. Influenza Other Respir Viruses. 2024 Nov;18(11):e7.  Abstract  
submitted by kickingbird at 2 days ago from Influenza Other Respir Viruses. 2024 Nov;18(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70042)
Background: Clinical data on patients infected with influenza B Victoria (BV) after the approval of baloxavir is lacking.Methods: This observational study of the Japanese 2023-2024 influenza season analyzed ...

Haman KH, Pearson SF, Brown J, Frisbie LA, Penhall. A comprehensive epidemiological approach documenting an outbreak of H5N1 highly pathogenic avian influenza virus clade 2.3.4.4b among gulls, terns, and harbor seals in the Northeastern Pacific. Front Vet Sci. 2024 Nov 1;11:1483922.  Abstract  
submitted by kickingbird at 3 days ago from Front Vet Sci. 2024 Nov 1;11:1483922 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Highly pathogenic avian influenza viruses (HPAIV) H5N1 clade 2.3.4.4b continue to have unprecedented global impacts on wild birds and mammals, with especially significant mortality observed in colonial ...

Youk S, Lee DH, Swayne DE, Killian ML, Torchetti M. Novel reassortant H2N2 low pathogenic avian influenza virus in live bird markets in the Northeastern United States, 2019-2023. Avian Pathol. 2024 Nov 18:1-7.  Abstract  
submitted by kickingbird at 3 days ago from Avian Pathol. 2024 Nov 18:1-7 (via https://www.tandfonline.com/doi/full/10.1080/03079457.2024.2)
The H2N2 avian influenza viruses (AIV) have been reported in the Northeast United States of America (USA) live bird market (LBM) system since 2014. In this study, we investigated the genetic evolution ...

Alexey Markin, Catherine A Macken, Amy L Baker,. [preprint]Revealing reassortment in influenza A viruses with TreeSort. https://doi.org/10.1101/2024.11.15.623781.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.15.623781 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623781v1)
Reassortment among influenza A viruses (IAV) facilitates genomic evolution and has been associated with interspecies transmission and pandemics. We introduce a novel tool called TreeSort that accurately ...

Chloe Qingzhou Huang, etc.,al. [preprint]Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses. https://doi.org/10.1101/2024.11.14.623359.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.14.623359 (via https://www.biorxiv.org/content/10.1101/2024.11.14.623359v1)
The increasing global spread of the highly pathogenic avian influenza (HPAI) A/H5 viruses poses a serious public health threat. Circulating clade 2.3.4.4b viruses have demonstrated rapid transcontinental ...

Pari H Baker, etc.,al. [preprint]Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates. https://doi.org/10.1101/2024.11.15.623885.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.15.623885 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623885v2)
The spread of H5N1 clade 2.3.4.4b in dairy herds raises concerns about zoonotic transmission due to the high viral load in milk, a key point of contact between livestock and humans. H5N1 clade 2.3.4.4b ...

Frutos AM, Ahmad HM, Ujamaa D, et al. Underutilization of Influenza Antiviral Treatment Among Children and Adolescents at Higher Risk for Influenza-Associated Complications - United States, 2023-2024. MMWR Morb Mortal Wkly Rep 2024;73:1022–1029.  Abstract  
submitted by kickingbird at 5 days ago from MMWR Morb Mortal Wkly Rep 2024;73:1022–1029 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7345a2.htm)
Annually, tens of thousands of U.S. children and adolescents are hospitalized with seasonal influenza virus infection. Both influenza vaccination and early initiation of antiviral treatment can reduce ...

Izumi H. Conformational Variability Prediction of Influenza Virus Hemagglutinins with Amino Acid Mutations Using Supersecondary Structure Code. Methods Mol Biol. 2025;2870:63-78.  Abstract  
submitted by kickingbird at 5 days ago from Methods Mol Biol. 2025;2870:63-78 (via https://link.springer.com/protocol/10.1007/978-1-0716-4213-9)
Supersecondary structure code (SSSC), which is represented as a conformation term using the letters "H," "S," "T," and "D" for each amino acid peptide unit, can be utilized to look up supersecondary structure ...

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