Tran V, Ledwith MP, Thamamongood T, et al. Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs. Nat Microbiol. 2020;10.1038/s41564-020-0778-x. Abstract
submitted by kickingbird at Aug, 26, 2020 from Nat Microbiol. 2020;10.1038/s41564-020-0778-x (via https://www.nature.com/articles/s41564-020-0778-x)
Cells infected by influenza virus mount a large-scale antiviral response and most cells ultimately initiate cell-death pathways in an attempt to suppress viral replication. We performed a CRISPR-Cas9-knockout ... Gu J, Gu M, Yan Y, et al. Detection of PB2 627K mutation in two highly pathogenic isolates of the H7N9 subtype influenza A virus from chickens in northern China. J Infect. 2020;S0163-4453(20)30558-2. Abstract
submitted by kickingbird at Aug, 25, 2020 from J Infect. 2020;S0163-4453(20)30558-2 (via https://pubmed.ncbi.nlm.nih.gov/32828821/)
PB2 E627K mutation of influenza A virus has been considered relevant to increased mammalian virulence and adaptation. In H7N9, the substitution is naturally confined to most human isolates and few low ... Hopken MW, Piaggio AJ, Pabilonia KL, et al. Population genomic transformations induced by isolation of wild bird avian influenza viruses (Orthomyxoviridae) in embryonated chicken eggs. Infect Genet Evol. 2020;104505. Abstract
submitted by kickingbird at Aug, 25, 2020 from Infect Genet Evol. 2020;104505 (via https://pubmed.ncbi.nlm.nih.gov/32827730/)
Isolation and cultivation of wild-type viruses in model organism cells or tissues is standard practice in virology. Oftentimes, the virus host species is distantly related to the species from which the ... Nilsson K, Abdurahman S, Schwartz S. Influenza virus natural sequence heterogeneity in segment 8 affects interactions with cellular RNA-binding proteins and splicing efficiency. Virology. 2020;549:39-50. Abstract
submitted by kickingbird at Aug, 25, 2020 from Virology. 2020;549:39-50 (via https://pubmed.ncbi.nlm.nih.gov/32829114/)
Segment 8 mRNAs of influenza virus A/Brevig Misson/1918/1 (H1N1) are poorly spliced compared to segment 8 mRNAs of influenza virus A/Netherlands/178/95 (H3N2). Using oligonucleotide-mediated protein pull ... Asadi S, Gaaloul Ben Hnia N, Barre RS, Wexler AS,. Influenza A virus is transmissible via aerosolized fomites. Nat Commun. 2020;11(1):4062.. Abstract
submitted by kickingbird at Aug, 21, 2020 from Nat Commun. 2020;11(1):4062. (via https://www.nature.com/articles/s41467-020-17888-w)
Influenza viruses are presumed, but not conclusively known, to spread among humans by several possible routes. We provide evidence of a mode of transmission seldom considered for influenza: airborne virus ... Xie J, Pang XL, Tarr GAM, et al. Influenza virus detection in the stool of children with acute gastroenteritis. J Clin Virol. 2020;131:104565. Abstract
submitted by kickingbird at Aug, 21, 2020 from J Clin Virol. 2020;131:104565 (via https://pubmed.ncbi.nlm.nih.gov/32810839/)
Objectives: To determine if the clinical characteristics of children with gastroenteritis and influenza identified in their stool differ from those whose stool was influenza-negative. Methods: Children ... Liu YM, Chen HC, Chen YC, et al. miR-1975 serves as an indicator of clinical severity upon influenza infection. Eur J Clin Microbiol Infect Dis. 2020;10.1007/s100. Abstract
submitted by kickingbird at Aug, 21, 2020 from Eur J Clin Microbiol Infect Dis. 2020;10.1007/s100 (via https://pubmed.ncbi.nlm.nih.gov/32814996/)
Emerging evidence highlights the role of non-coding small RNAs in host-influenza interaction. We have identified a Y RNA-derived small RNA, miR-1975, which is upregulated upon influenza A virus infection ... Shubina M, Tummers B, Boyd DF, et al. Necroptosis restricts influenza A virus as a stand-alone cell death mechanism. J Exp Med. 2020;217(11):e20191259. Abstract
submitted by kickingbird at Aug, 18, 2020 from J Exp Med. 2020;217(11):e20191259 (via https://pubmed.ncbi.nlm.nih.gov/32797196/)
Influenza A virus (IAV) activates ZBP1-initiated RIPK3-dependent parallel pathways of necroptosis and apoptosis in infected cells. Although mice deficient in both pathways fail to control IAV and succumb ... Patel MC, Mishin VP, De La Cruz JA, et al. Detection of baloxavir resistant influenza A viruses using next generation sequencing and pyrosequencing methods. Antiviral Res. 2020;104906. Abstract
submitted by kickingbird at Aug, 18, 2020 from Antiviral Res. 2020;104906 (via https://pubmed.ncbi.nlm.nih.gov/32798601/)
Baloxavir, a new antiviral drug targeting cap-dependent endonuclease activity of polymerase acidic (PA) protein of influenza viruses, is now approved in multiple countries. Several substitutions at isoleucine ... Jiang W, Li Z, Liu S, et al. Genetic characterization of a highly pathogenic H5N6 avian influenza virus isolated from greylag goose. J Infect. 2020;S0163-4453(20)30550-8. Abstract
submitted by kickingbird at Aug, 18, 2020 from J Infect. 2020;S0163-4453(20)30550-8 (via https://pubmed.ncbi.nlm.nih.gov/32800799/)
We isolated and characterized a highly pathogenic H5N6 avian influenza virus in wild birds during avian influenza virus surveillance in 2020. The GG1/H5N6 virus was highly pathogenic. Several mutations ... Yuyun I, Wibawa H, Setiaji G, Kusumastuti TA, Nugr. Determining highly pathogenic H5 avian influenza clade 2.3.2.1c seroprevalence in ducks, Purbalingga, Central Java, Indonesia. Vet World . 2020 Jun;13(6):1138-1144. Abstract
submitted by kickingbird at Aug, 18, 2020 from Vet World . 2020 Jun;13(6):1138-1144 (via https://pubmed.ncbi.nlm.nih.gov/32801565/)
Background and aim: In Indonesia, highly pathogenic avian influenza (HPAI) H5N1 outbreaks in poultry are still reported. The disease causes a decrease in egg production and an increase in mortality; this ... Weinan Zheng, et al. Nucleoprotein phosphorylation site (Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature. Sci China Life Sci . 2020 Aug 11. Abstract
submitted by kickingbird at Aug, 18, 2020 from Sci China Life Sci . 2020 Aug 11 (via https://pubmed.ncbi.nlm.nih.gov/32803713/)
Mutations in viral proteins can lead to the cold adaption of influenza A virus and the cold-adapted virus is an important vaccination instrument. Here, we identify a novel strain of influenza A virus with ... Ming Zhong, et al. Amide-sialoside protein conjugates as neomucin bioshields prevent influenza virus infection. Carbohydr Res . 2020 Sep;495:108088.. Abstract
submitted by kickingbird at Aug, 18, 2020 from Carbohydr Res . 2020 Sep;495:108088. (via https://pubmed.ncbi.nlm.nih.gov/32807356/)
We report the preparation of multivalent amide-sialoside-decorated human serum albumin (HSA) and bovine serum albumin (BSA) as mimics of natural mucin and bioshields against influenza virus infection. ... Zhang M, Zhao C, Chen H, et al. Internal Gene Cassette From a Human-Origin H7N9 Influenza Virus Promotes the Pathogenicity of H9N2 Avian Influenza Virus in Mice. Front Microbiol. 2020;11:1441. Abstract
submitted by kickingbird at Aug, 17, 2020 from Front Microbiol. 2020;11:1441 (via https://pubmed.ncbi.nlm.nih.gov/32793127/)
H9N2 avian influenza virus is one of the most widely circulating viruses in poultry and poses a huge potential threat to human health due to its frequent gene reassortment with other influenza viruses. ... Fay EJ, Aron SL, Macchietto MG, et al. Cell type- and replication stage-specific influenza virus responses in vivo. PLoS Pathog. 2020;16(8):e1008760. Abstract
submitted by kickingbird at Aug, 17, 2020 from PLoS Pathog. 2020;16(8):e1008760 (via https://pubmed.ncbi.nlm.nih.gov/32790753/)
Influenza A viruses (IAVs) remain a significant global health burden. Activation of the innate immune response is important for controlling early virus replication and spread. It is unclear how early IAV ... Lim K, Kodera N, Wang H, et al. High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes. Nano Lett. 2020;10.1021/acs.nanolett.0c01755. Abstract
submitted by kickingbird at Aug, 14, 2020 from Nano Lett. 2020;10.1021/acs.nanolett.0c01755 (via https://pubmed.ncbi.nlm.nih.gov/32787163/)
Influenza A hemagglutinin (HA) is one of the crucial virulence factors that mediate host tropism and viral infectivity. Presently, the mechanism of the fusogenic transition of HA remains elusive. Here, ... Liang WS, He YC, Wu HD, et al. Ecological factors associated with persistent circulation of multiple highly pathogenic avian influenza viruses among poultry farms in Taiwan during 2015~17. PLoS One. 2020;15(8):e0236581. Abstract
submitted by kickingbird at Aug, 14, 2020 from PLoS One. 2020;15(8):e0236581 (via https://pubmed.ncbi.nlm.nih.gov/32790744/)
Emergence and intercontinental spread of highly pathogenic avian influenza A (HPAI) H5Nx virus clade 2.3.4.4 has resulted in substantial economic losses to the poultry industry in Asia, Europe, and North ... Liu K, Gao R, Wang X, et al. Pathogenicity and transmissibility of clade 2.3.4.4 highly pathogenic avian influenza virus subtype H5N6 in pigeons. Vet Microbiol. 2020;247:108776. Abstract
submitted by kickingbird at Aug, 10, 2020 from Vet Microbiol. 2020;247:108776 (via https://pubmed.ncbi.nlm.nih.gov/32768222/)
Pigeons were previously thought to be resistant to H5 viruses and to play a minimal role in spreading these viruses. In this study, we evaluated the pathogenicity of two clade 2.3.4.4 H5N6 viruses in pigeons ... Lycett SJ, Pohlmann A, Staubach C, et al. Genesis and spread of multiple reassortants during the 2016/2017 H5 avian influenza epidemic in Eurasia. Proc Natl Acad Sci U S A. 2020;202001813. Abstract
submitted by kickingbird at Aug, 10, 2020 from Proc Natl Acad Sci U S A. 2020;202001813 (via https://pubmed.ncbi.nlm.nih.gov/32769208/)
Highly pathogenic avian influenza (HPAI) viruses of the H5 A/goose/Guangdong/1/96 lineage can cause severe disease in poultry and wild birds, and occasionally in humans. In recent years, H5 HPAI viruses ... Yu CM, Chen IC, Tung CP, et al. A panel of anti-influenza virus nucleoprotein antibodies selected from phage-displayed synthetic antibody libraries with rapid diagnostic capability to distinguish diverse influenza virus subtypes. Sci Rep. 2020;10(1):13318. Abstract
submitted by kickingbird at Aug, 10, 2020 from Sci Rep. 2020;10(1):13318 (via https://pubmed.ncbi.nlm.nih.gov/32770098/)
Immunoassays based on sandwich immuno-complexes of capture and detection antibodies simultaneously binding to the target analytes have been powerful technologies in molecular analyses. Recent developments ... 5328 items, 20/Page, Page[82/267][|<<] [|<] [81] [82] [83] [84] [85] [86] [87] [88] [89] [90] [>|] [>>|] |
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