Namba T, Tsuge M, Yashiro M, Saito Y, Liu K, Nishi. Anti-high mobility group box 1 monoclonal antibody suppressed hyper-permeability and cytokine production in human pulmonary endothelial cells infected with influenza A virus. Inflamm Res. 2021 Aug 29. Abstract
submitted by kickingbird at Aug, 30, 2021 from Inflamm Res. 2021 Aug 29 (via https://link.springer.com/article/10.1007%2Fs00011-021-01496)
Objective: High mobility group box-1 (HMGB1) has been reported to be involved in influenza A virus-induced acute respiratory distress syndrome (ARDS). We studied the efficacy of an anti-HMGB1 mAb using ... Jerry C, Stallknecht DE, Leyson C, Berghaus R, Jor. Age-Associated Changes in Recombinant H5 Highly Pathogenic and Low Pathogenic Avian Influenza Hemagglutinin Tissue Binding in Domestic Poultry Species. Animals (Basel). 2021 Jul 28;11(8):2223. Abstract
submitted by kickingbird at Aug, 30, 2021 from Animals (Basel). 2021 Jul 28;11(8):2223 (via https://www.mdpi.com/2076-2615/11/8/2223)
The 2014 outbreak of clade 2.3.4.4A highly pathogenic avian influenza (HPAI) led to the culling of millions of commercial chickens and turkeys and death of various wild bird species. In this outbreak, ... Tarek M, Naguib MM, Arafa AS, Tantawy LA, Selim KM. Epidemiology, Genetic Characterization, and Pathogenesis of Avian Influenza H5N8 Viruses Circulating in Northern and Southern Parts of Egypt, 2017-2019. Animals (Basel). 2021 Jul 26;11(8):2208. Abstract
submitted by kickingbird at Aug, 30, 2021 from Animals (Basel). 2021 Jul 26;11(8):2208 (via https://www.mdpi.com/2076-2615/11/8/2208)
Highly pathogenic avian influenza (HPAI) viruses of subtype H5N8 continue to circulate, causing huge economic losses and serious impact on poultry production worldwide. Recently, HPAIV H5N8 has been spreading ... Yeo SJ, Hoang VT, Duong TB, Nguyen NM, Tuong HT, A. Emergence of a Novel Reassortant H5N3 Avian Influenza Virus in Korean Mallard Ducks in 2018. Intervirology. 2021 Aug 26:1-16. Abstract
submitted by kickingbird at Aug, 30, 2021 from Intervirology. 2021 Aug 26:1-16 (via https://www.karger.com/Article/FullText/517057)
Introduction: The avian influenza (AI) virus causes a highly contagious disease which is common in wild and domestic birds and sporadic in humans. Mutations and genetic reassortments among the 8 negative-sense ... Jones JE, Le Sage V, Padovani GH, Calderon M, Wrig. Parallel evolution between genomic segments of seasonal human influenza viruses reveals RNA-RNA relationships. Elife. 2021 Aug 27;10:e66525. Abstract
submitted by kickingbird at Aug, 30, 2021 from Elife. 2021 Aug 27;10:e66525 (via https://elifesciences.org/articles/66525)
The influenza A virus (IAV) genome consists of eight negative-sense viral RNA (vRNA) segments that are selectively assembled into progeny virus particles through RNA-RNA interactions. To explore putative ... Ali M, Yaqub T, Shahid MF, Wong FY, Mukhtar N, Nae. Genetic Characterization of Highly Pathogenic Avian Influenza A(H5N8) Virus in Pakistani Live Bird Markets Reveals Rapid Diversification of Clade 2.3.4.4b Viruses. Viruses. 2021 Aug 18;13(8):1633. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 18;13(8):1633 (via https://www.mdpi.com/1999-4915/13/8/1633)
The highly pathogenic (HPAI) avian influenza A(H5N1) viruses have undergone reassortment with multiple non-N1-subtype neuraminidase genes since 2008, leading to the emergence of H5Nx viruses. H5Nx viruses ... Zhang X, Bo Z, Meng C, Chen Y, Zhang C, Cao Y, Wu. Generation and Evaluation of Recombinant Thermostable Newcastle Disease Virus Expressing the HA of H9N2 Avian Influenza Virus. Viruses. 2021 Aug 13;13(8):1606. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 13;13(8):1606 (via https://www.mdpi.com/1999-4915/13/8/1606)
H9N2 avian influenza virus (AIV) has become endemic in many countries, causing great economic losses when co-infected with other pathogens. So far, several live vaccines based on Newcastle disease virus ... Treshchalina A, Postnikova Y, Boravleva E, Gambary. Substitution Arg140Gly in Hemagglutinin Reduced the Virulence of Highly Pathogenic Avian Influenza Virus H7N1. Viruses. 2021 Aug 11;13(8):1584. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 11;13(8):1584 (via https://www.mdpi.com/1999-4915/13/8/1584)
The H7 subtype of avian influenza viruses (AIV) stands out among other AIV. The H7 viruses circulate in ducks, poultry and equines and have repeatedly caused outbreaks of disease in humans. The laboratory ... Amer F, Li R, Rabie N, El-Husseiny MH, Yehia N, Ha. Temporal Dynamics of Influenza A(H5N1) Subtype before and after the Emergence of H5N8. Viruses. 2021 Aug 7;13(8):1565. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 7;13(8):1565 (via https://www.mdpi.com/1999-4915/13/8/1565)
Highly pathogenic avian influenza (HPAI) viruses continue to circulate worldwide, causing numerous outbreaks among bird species and severe public health concerns. H5N1 and H5N8 are the two most fundamental ... Steinberg J, Wadenpohl T, Jung S. The Endogenous RIG-I Ligand Is Generated in Influenza A-Virus Infected Cells. Viruses. 2021 Aug 7;13(8):1564. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 7;13(8):1564 (via https://www.mdpi.com/1999-4915/13/8/1564)
As a result of a viral infection, viral genomes are not only recognized by RIG-I, but also lead to the activation of RNase L, which cleaves cellular RNA to generate the endogenous RIG-I ligand (eRL). The ... Rozek W, Kwasnik M, Socha W, Sztromwasser P, Rola. Analysis of Single Nucleotide Variants (SNVs) Induced by Passages of Equine Influenza Virus H3N8 in Embryonated Chicken Eggs. Viruses. 2021 Aug 5;13(8):1551. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 5;13(8):1551 (via https://www.mdpi.com/1999-4915/13/8/1551)
Vaccination is an effective method for the prevention of influenza virus infection. Many manufacturers use embryonated chicken eggs (ECE) for the propagation of vaccine strains. However, the adaptation ... Oladunni FS, Oseni SO, Martinez-Sobrido L, Chamber. Equine Influenza Virus and Vaccines. Viruses. 2021 Aug 20;13(8):1657. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 20;13(8):1657 (via https://www.mdpi.com/1999-4915/13/8/1657)
Equine influenza virus (EIV) is a constantly evolving viral pathogen that is responsible for yearly outbreaks of respiratory disease in horses termed equine influenza (EI). There is currently no evidence ... Frymus T, Belák S, Egberink H, Hofmann-Lehmann R,. Influenza Virus Infections in Cats. Viruses. 2021 Jul 23;13(8):1435. Abstract
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Jul 23;13(8):1435 (via https://www.mdpi.com/1999-4915/13/8/1435)
In the past, cats were considered resistant to influenza. Today, we know that they are susceptible to some influenza A viruses (IAVs) originating in other species. Usually, the outcome is only subclinical ... Stadtmueller MN, Bhatia S, Kiran P, Hilsch M, Reit. Evaluation of Multivalent Sialylated Polyglycerols for Resistance Induction in and Broad Antiviral Activity against Influenza A Viruses. J Med Chem. 2021 Aug 25. Abstract
submitted by kickingbird at Aug, 26, 2021 from J Med Chem. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00794)
The development of multivalent sialic acid-based inhibitors active against a variety of influenza A virus (IAV) strains has been hampered by high genetic and structural variability of the targeted viral ... Wilks LR, Joshi G, Grisham MR, Gill HS. Tyrosine-Based Cross-Linking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A. ACS Infect Dis. 2021 Aug 25. Abstract
submitted by kickingbird at Aug, 26, 2021 from ACS Infect Dis. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00219)
A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine cross-linking reaction. A reactive tag comprising histidine and tyrosine ... Zhang J, Ma K, Li B, Chen Y, Qiu Z, Xing J, Huang. A risk marker of tribasic hemagglutinin cleavage site in influenza A (H9N2) virus. Commun Biol. 2021 Jan 15;4(1):71. Abstract
submitted by kickingbird at Aug, 25, 2021 from Commun Biol. 2021 Jan 15;4(1):71 (via https://www.nature.com/articles/s42003-020-01589-7)
Low pathogenic avian influenza A(H9N2) virus is endemic worldwide and continually recruit internal genes to generate human-infecting H5N1, H5N6, H7N9, and H10N8 influenza variants. Here we show that hemagglutinin ... Li X, Gu M, Wang X, Gao R, Bu X, Hao X, Ma J, Hu J. G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment. BMC Vet Res. 2021 Feb 15;17(1):80. Abstract
submitted by kickingbird at Aug, 25, 2021 from BMC Vet Res. 2021 Feb 15;17(1):80 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such ... Blaurock C, Blohm U, Luttermann C, Holzerland J, S. The C-Terminus of Non-Structural Protein 1 (NS1) in H5N8 Clade 2.3.4.4 Avian Influenza Virus Affects Virus Fitness in Human Cells and Virulence in Mice. Emerg Microbes Infect. 2021 Aug 22:1-48.. Abstract
submitted by kickingbird at Aug, 24, 2021 from Emerg Microbes Infect. 2021 Aug 22:1-48. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) ... Han T, Lai Y, Jiang Y, Liu X, Li D. Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines. PeerJ. 2021 Aug 3;9:e11892. Abstract
submitted by kickingbird at Aug, 22, 2021 from PeerJ. 2021 Aug 3;9:e11892 (via https://peerj.com/articles/11892/)
Objective: To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.Methods: Human pulmonary ... Flores-Torres AS, Rendon A, Salinas-Carmona MC, Sa. Human Eosinophils Reduce Viral Titer, Secrete IL-8, and Increase RIG-I Expression in Response to Influenza A H1N1 pdm09. Viral Immunol. 2021 Aug 19. Abstract
submitted by kickingbird at Aug, 22, 2021 from Viral Immunol. 2021 Aug 19 (via https://www.liebertpub.com/doi/10.1089/vim.2021.0004)
Eosinophils participate in the immune response against many pathogens, including viruses. Since mouse eosinophils are susceptible to influenza A virus infection and possess antiviral activity, we evaluated ... 5586 items, 20/Page, Page[72/280][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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