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2024-11-24 4:16:03
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Fiona Greco, etc.,al. [preprint]Asymptomatic infection and antibody prevalence to co-occurring avian influenza viruses vary substantially between sympatric seabird species following H5N1 outbreaks. https://doi.org/10.1101/2024.09.26.614314.  Abstract  
submitted by kickingbird at Sep, 29, 2024 from https://doi.org/10.1101/2024.09.26.614314 (via https://www.biorxiv.org/content/10.1101/2024.09.26.614314v1)
Emerging infectious diseases are of major concern to animal and human health. Recent emergence of high pathogenicity avian influenza virus (HPAIV) (H5N1 clade 2.3.4.4b) led to substantial global mortality ...

Jiayun Yang, etc.,al. [preprint]The Haemagglutinin Gene of Bovine Origin H5N1 Influenza Viruses Currently Retains an Avian Influenza Virus phenotype.. https://doi.org/10.1101/2024.09.27.615407.  Abstract  
submitted by kickingbird at Sep, 29, 2024 from https://doi.org/10.1101/2024.09.27.615407 (via https://www.biorxiv.org/content/10.1101/2024.09.27.615407v1)
Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) has caused a panzootic affecting all continents except Australia, expanding its host range to several mammalian species. In March 2024, ...

Daniel Weir, etc.,al. [preprint]Influenza A viruses induce tunnelling nanotube-like structures through the onset of apoptosis. https://doi.org/10.1101/2024.09.25.614890.  Abstract  
submitted by kickingbird at Sep, 29, 2024 from https://doi.org/10.1101/2024.09.25.614890 (via https://www.biorxiv.org/content/10.1101/2024.09.25.614890v1)
As well as spreading through virions, influenza A viruses (IAVs) can evade antiviral drugs and neutralising antibodies by spreading directly from cell to cell. In cell culture this can occur by the induction ...

Marni E. Cueno, Noriaki Kamio, Kenichi Imai. Avian influenza A H5N1 hemagglutinin protein models have distinct structural patterns re-occurring across the 1959-2023 strains. BioSystems 28 September 2024, 105347.  Abstract  
submitted by kickingbird at Sep, 29, 2024 from BioSystems 28 September 2024, 105347 (via https://www.sciencedirect.com/science/article/abs/pii/S03032)
Influenza A H5N1 hemagglutinin (HA) plays a crucial role in viral pathogenesis and changes in the HA receptor binding domain (RBD) have been attributed to alterations in viral pathogenesis. Mutations often ...

Cai Y, Yin G, Hu J, Liu Y, Huang X, Gao Z, Guo X,. Preparation and Antigenic Site Identification of Monoclonal Antibodies against PB1 Protein of H9N2 Subtype AIV. Vet Sci. 2024 Sep 5;11(9):412.  Abstract  
submitted by kickingbird at Sep, 28, 2024 from Vet Sci. 2024 Sep 5;11(9):412 (via https://www.mdpi.com/2306-7381/11/9/412)
Recently, low pathogenic avian influenza virus (LPAIV), including H9N2 subtype, has been common clinical epidemic strains, and is widely distributed globally. The PB1 protein is a key component of the ...

Zhang Y, Zhang C, Li J, Yang Y, Chen L, Wang H, Ya. Establishment of a Real-Time Fluorescence Isothermal Recombinase-Aided Amplification Method for the Detection of H9 Avian Influenza Virus. Vet Sci. 2024 Sep 5;11(9):411.  Abstract  
submitted by kickingbird at Sep, 28, 2024 from Vet Sci. 2024 Sep 5;11(9):411 (via https://www.mdpi.com/2306-7381/11/9/411)
The H9 subtype of avian influenza virus (AIV) has been characterized by its rapid spread, wide range of prevalence, and continuous evolution in recent years, leading to an increasing ability for cross-species ...

Lin Y, Wang Y, Li H, Liu T, Zhang J, Guo X, Guo W,. A platform for the rapid screening of equine immunoglobins F (ab)2 derived from single equine memory B cells able to cross-neutralize to influenza virus. Emerg Microbes Infect. 2024 Dec;13(1):2396864.  Abstract  
submitted by kickingbird at Sep, 28, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2396864 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Single B cells-based antibody platforms offer an effective approach for the discovery of useful antibodies for therapeutic or research purposes. Here we present a method for screening equine immunoglobins ...

Margaret A. Honein, Sonja J. Olsen, Daniel B. Jern. Challenges and Opportunities for Wastewater Monitoring of Influenza Viruses During the Multistate Outbreak of Highly Pathogenic Avian Influenza A(H5N1) Virus in Dairy Cattle and Poultry. American Journal of Public Health 0, e1_e4.  Abstract  
submitted by kickingbird at Sep, 27, 2024 from American Journal of Public Health 0, e1_e4 (via https://ajph.aphapublications.org/doi/10.2105/AJPH.2024.3078)
The Centers for Disease Control and Prevention (CDC) began wastewater monitoring in September 2020 to pro-vide additional information to healthcare providers and the public on thelevel of transmission ...

Halwe, N.J., Cool, K., Breithaupt, A. et al. H5N1 clade 2.3.4.4b dynamics in experimentally infected calves and cows. Nature (2024).  Abstract  
submitted by kickingbird at Sep, 26, 2024 from Nature (2024) (via https://www.nature.com/articles/s41586-024-08063-y)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4b H5N1 infections in dairy cows were first reported from Texas, USA1. Rapid dissemination to more than 190 farms in 13 states ...

Yang S, Zhang Q. Exponential stability and fixed-time control of a stochastic avian influenza model with spatial diffusion and nonlocal delay. Chaos. 2024 Sep 1;34(9):093132.  Abstract  
submitted by kickingbird at Sep, 25, 2024 from Chaos. 2024 Sep 1;34(9):093132 (via https://pubs.aip.org/aip/cha/article-abstract/34/9/093132/33)
Spatial heterogeneity, random disturbances in the external environment, and the incubation period of infected individuals collectively have a significant impact on the outbreak of avian influenza. In this ...

Chen X, Tao F, Chen Y, Cheng J, Zhou Y, Wang X. Forecasting influenza epidemics in China using transmission dynamic model with absolute humidity. Infect Dis Model. 2024 Aug 10;10(1):50-59.  Abstract  
submitted by kickingbird at Sep, 25, 2024 from Infect Dis Model. 2024 Aug 10;10(1):50-59 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Background: An influenza forecasting system is critical to influenza epidemic preparedness. Low temperature has long been recognized as a condition favoring influenza epidemic, yet it fails to justify ...

Zhang Y, Kong W, Wu Y, Chen Z, Zhao X, Liu M. Reducing amplification cycles to improve the coverage of influenza A virus genome sequencing in heterosubtypic co-infection. J Virol Methods. 2024 Sep 20:115036.  Abstract  
submitted by kickingbird at Sep, 23, 2024 from J Virol Methods. 2024 Sep 20:115036 (via https://www.sciencedirect.com/science/article/pii/S016609342)
This study delineates the enhancement of a Reverse Transcription Polymerase Chain Reaction (RT-PCR) method for the amplification of the complete genome of the influenza A virus during heterosubtypic co-infection, ...

Ichikawa T, Hiono T, Okamatsu M, Maruyama J, Kobay. Hemagglutinin and neuraminidase of a non-pathogenic H7N7 avian influenza virus coevolved during the acquisition of intranasal pathogenicity in chickens. Arch Virol. 2024 Sep 22;169(10):207.  Abstract  
submitted by kickingbird at Sep, 23, 2024 from Arch Virol. 2024 Sep 22;169(10):207 (via https://link.springer.com/article/10.1007/s00705-024-06118-z)
Polybasic amino acid residues at the hemagglutinin (HA) cleavage site are insufficient to induce the highly pathogenic phenotype of avian influenza viruses in chickens. In our previous study, an H7N7 avian ...

Baumberger C, Anríquez G, Galdames P, Palma T, Gon. Exposure Practices to Animal-Origin Influenza A Virus at the Animal-Human Interface in Poultry and Swine Backyard Farms. Zoonoses Public Health. 2024 Sep 20.  Abstract  
submitted by kickingbird at Sep, 22, 2024 from Zoonoses Public Health. 2024 Sep 20 (via https://pubmed.ncbi.nlm.nih.gov/39304348/)
Aim: Backyard production systems (BPS) represent an interface of contact between people, domestic and wild animals. Studies conducted in Chile during the last decade have provided extensive evidence of ...

Louis S, Mark-Carew M, Biggerstaff M, et al. Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases - United Stat. MMWR Morb Mortal Wkly Rep 2024;73:804–809.  Abstract  
submitted by kickingbird at Sep, 20, 2024 from MMWR Morb Mortal Wkly Rep 2024;73:804–809 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7337a1.htm)
As part of the response to the highly pathogenic avian influenza A(H5N1) virus outbreak in U.S. cattle and poultry and the associated human cases, CDC and partners are monitoring influenza A virus levels ...

Sircy LM, Ramstead AG, Gibbs LC, Joshi H, Baessler. Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection. PLoS Pathog. 2024 Sep 16;20(9):e1011639.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from PLoS Pathog. 2024 Sep 16;20(9):e1011639 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Current influenza vaccine strategies have yet to overcome significant obstacles, including rapid antigenic drift of seasonal influenza viruses, in generating efficacious long-term humoral immunity. Due ...

Ahlstrom CA, Torchetti MK, Lenoch J, Beckmen K, Bo. Genomic characterization of highly pathogenic H5 avian influenza viruses from Alaska during 2022 provides evidence for genotype-specific trends of spatiotemporal and interspecies dissemination. Emerg Microbes Infect. 2024 Sep 17:2406291.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from Emerg Microbes Infect. 2024 Sep 17:2406291 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The ongoing panzootic of highly pathogenic H5 clade 2.3.4.4b avian influenza (HPAI) spread to North America in late 2021, with detections of HPAI viruses in Alaska beginning in April 2022. HPAI viruses ...

Yue X, Zhong C, Cao R, Liu S, Qin Z, Liu L, Zhai Y. CircRNA based multivalent neuraminidase vaccine induces broad protection against influenza viruses in mice. NPJ Vaccines. 2024 Sep 16;9(1):170.  Abstract  
submitted by kickingbird at Sep, 18, 2024 from NPJ Vaccines. 2024 Sep 16;9(1):170 (via https://www.nature.com/articles/s41541-024-00963-4)
Developing broad-spectrum influenza vaccines is crucial for influenza control and potential pandemic preparedness. Here, we reported a novel vaccine design utilizing circular RNA (circRNA) as a delivery ...

Benito AA, Monteagudo LV, Lázaro-Gaspar S, Mazas-C. Detection and subtyping of influenza A virus in porcine clinical samples from Spain in 2020. Virology. 2024 Sep 8;600:110223.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from Virology. 2024 Sep 8;600:110223 (via https://www.sciencedirect.com/science/article/pii/S004268222)
A total of 1019 samples collected on 726 Spanish swine farms suffering from outbreaks of respiratory disease were screened for influenza A viruses (IAVs) using a RT-qPCR method. A subset of positive samples ...

Root JJ, Porter SM, Lenoch JB, Ellis JW, Bosco-La. Susceptibilities and viral shedding of peridomestic wildlife infected with clade 2.3.4.4b highly pathogenic avian influenza virus (H5N1). Virology. 2024 Sep 5;600:110231.  Abstract  
submitted by kickingbird at Sep, 17, 2024 from Virology. 2024 Sep 5;600:110231 (via https://www.sciencedirect.com/science/article/pii/S004268222)
We tested the ability of six peridomestic wildlife species to replicate a highly pathogenic (HP) clade 2.3.4.4b AIV (H5N1) isolated in the U.S. during 2022. All tested species replicated and shed virus, ...

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