Thielen P, et al. Complete Genome Sequence of an Influenza D Virus Strain Identified in a Pig with Subclinical Infection in the United States. Microbiol Resour Announc. 2019 Jan 24;8(4). Abstract
submitted by kickingbird at Feb, 3, 2019 from Microbiol Resour Announc. 2019 Jan 24;8(4) (via https://www.ncbi.nlm.nih.gov/pubmed/30701240)
Influenza D virus was first described in 2011 from a pig with respiratory disease; however, recent evidence indicates that cattle are the major viral reservoir. Here, we describe the genome sequence of ...
Zou S, et al. Molecular characterization and receptor binding specificity of H9N2 avian influenza viruses based on poultry-related environmental surveillance in China between 2013 and 2016. Virology. 2019 Jan 3;529:135-143.. Abstract
submitted by kickingbird at Feb, 3, 2019 from Virology. 2019 Jan 3;529:135-143. (via https://www.ncbi.nlm.nih.gov/pubmed/30703577)
H9N2 avian influenza viruses (AIVs) have become panzootic and caused sporadic human cases since 1998. Based on the poultry-related environmental surveillance data in mainland China from 2013 to 2016, a ...
Li X, Zhang Y, Zou S, Bo H, Wang D, Shu Y. Method for Sequencing the Whole Genome of the Highly Pathogenic Avian Influenza A(H5N6) Virus. Bing Du Xue Bao. 2017 Jan;33(1):19-23. Abstract
submitted by kickingbird at Feb, 3, 2019 from Bing Du Xue Bao. 2017 Jan;33(1):19-23 (via https://www.ncbi.nlm.nih.gov/pubmed/30702817)
We wished to develop a simple method to amplify and sequence the whole genome of the highly pathogenic avian influenza A ( H5N6 ) virus. Hemagglutinin ( HA ) gene sequences of A ( H5), neuraminidase (NA) ...
Cheng Y, Huang W, Li X, Wei H, Tan M, et al. Effect of Oseltamivir on the Hemagglutination Test and Hemagglutination Inhibition Test of the Influenza A(H3N2) Virus in China. Bing Du Xue Bao. 2017 Jan;33(1):13-18. Abstract
submitted by kickingbird at Feb, 3, 2019 from Bing Du Xue Bao. 2017 Jan;33(1):13-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30702816)
We compared the effect of oseltamivir on the hemagglutination (HA) test and hemagglutinin inhibition (HI) test of the influenza A(H3N2) virus in China to obtain the "true" HA titer and antigenic variation. ...
Shannon I, et al. Differences in the influenza-specific CD4 T cell immunodominance hierarchy and functional potential between children and young adults. Sci Rep. 2019 Jan 28;9(1):791.. Abstract
submitted by kickingbird at Jan, 31, 2019 from Sci Rep. 2019 Jan 28;9(1):791. (via https://www.ncbi.nlm.nih.gov/pubmed/30692574)
Studies of the B cell repertoire suggest that early childhood influenza infections profoundly shape later reactivity by creating an "imprint" that impacts subsequent vaccine responses and may provide lasting ...
Miyake Y, et al. Influenza virus uses transportin 1 for vRNP debundling during cell entry. Nat Microbiol. 2019 Jan 28. Abstract
submitted by kickingbird at Jan, 31, 2019 from Nat Microbiol. 2019 Jan 28 (via https://www.ncbi.nlm.nih.gov/pubmed/30692667)
Influenza A virus is a pathogen of great medical impact. To develop novel antiviral strategies, it is essential to understand the molecular aspects of virus-host cell interactions in detail. During entry, ...
Jung HE, Oh JE, Lee HK. Cell-Penetrating Mx1 Enhances Anti-Viral Resistance against Mucosal Influenza Viral Infection. Viruses. 2019 Jan 28;11(2). Abstract
submitted by kickingbird at Jan, 31, 2019 from Viruses. 2019 Jan 28;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30696001)
Dynamin-like GTPase myxovirus resistance protein 1 (Mx1) is an intracellular anti-viral protein following the activation of type I and type III interferon signaling. Mx1 inhibits viral replication by blocking ...
La Sala LF, et al. Spatial modeling for low pathogenicity avian influenza virus at the interface of wild birds and backyard poultry. Transbound Emerg Dis. 2019 Jan 30. Abstract
submitted by kickingbird at Jan, 31, 2019 from Transbound Emerg Dis. 2019 Jan 30 (via https://www.ncbi.nlm.nih.gov/pubmed/30698918)
Low pathogenicity avian influenza virus (LPAIV) is endemic in wild birds and poultry in Argentina, and active surveillance has been in place to prevent any eventual virus mutation into a highly pathogenic ...
Majarian TD, Murphy RF, Lakdawala SS. Learning the sequence of influenza A genome assembly during viral replication using point process models and fluorescence in situ hybridization. PLoS Comput Biol. 2019 Jan 28;15(1). Abstract
submitted by kickingbird at Jan, 30, 2019 from PLoS Comput Biol. 2019 Jan 28;15(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30689627)
Within influenza virus infected cells, viral genomic RNA are selectively packed into progeny virions, which predominantly contain a single copy of 8 viral RNA segments. Intersegmental RNA-RNA interactions ...
Shehata AA. Co-infections, genetic, and antigenic relatedness of avian influenza H5N8 and H5N1 viruses in domestic and wild birds in Egypt. Poult Sci. 2019 Jan 22.. Abstract
submitted by kickingbird at Jan, 27, 2019 from Poult Sci. 2019 Jan 22. (via https://www.ncbi.nlm.nih.gov/pubmed/30668795)
A total of 50 poultry farms of commercial broilers (N = 39) and commercial layers (N = 11) suffered from respiratory problems and mortality during the period from January 2016 to December 2017 were investigated. ...
Yang L, et al. Attenuation of IRF7 activity in local infectious sites of trachea and lung for preventing the development of acute lung injury caused by influenza A virus. Immunology. 2019 Jan 22.. Abstract
submitted by kickingbird at Jan, 27, 2019 from Immunology. 2019 Jan 22. (via https://www.ncbi.nlm.nih.gov/pubmed/30667045)
The excessive activation of interferon regulatory factor 7 (IRF7) promotes the development of acute lung injury (ALI) caused by influenza A virus (IAV). However, the deficiency of IRF7 increases the susceptibility ...
Campos ACA, et al. Bat Influenza A(HL18NL11) Virus in Fruit Bats, Brazil. Emerg Infect Dis. 2019 Feb;25(2):333-337. Abstract
submitted by kickingbird at Jan, 27, 2019 from Emerg Infect Dis. 2019 Feb;25(2):333-337 (via https://www.ncbi.nlm.nih.gov/pubmed/30666923)
Screening of 533 bats for influenza A viruses showed subtype HL18NL11 in intestines of 2 great fruit-eating bats (Artibeus lituratus). High concentrations suggested fecal shedding. Genomic characterizations ...
Wei X, et al. The interaction of cellular protein ANP32A with influenza A virus polymerase component PB2 promotes vRNA synthesis. Arch Virol. 2019 Jan 21. Abstract
submitted by kickingbird at Jan, 27, 2019 from Arch Virol. 2019 Jan 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30666459)
The subunits PA, PB1, and PB2 of influenza A virus RNA polymerase are essential for efficient viral RNA synthesis and virus replication because of their role in recruiting multiple nuclear proteins. ANP32A ...
Wüthrich D, et al. Evaluation of two workflows for whole genome sequencing-based typing of influenza A viruses. J Virol Methods. 2019 Jan 21. Abstract
submitted by kickingbird at Jan, 26, 2019 from J Virol Methods. 2019 Jan 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30677464)
We compared two sample preparation protocols for whole genome sequencing of influenza A viruses. Each protocol was assessed using cDNA quantity and quality and the resulting mean genome coverage after ...
Wu H, et al. Generation of H7N9-specific human polyclonal antibodies from a transchromosomic goat (caprine) system. Sci Rep. 2019 Jan 23;9(1):366. Abstract
submitted by kickingbird at Jan, 26, 2019 from Sci Rep. 2019 Jan 23;9(1):366 (via https://www.ncbi.nlm.nih.gov/pubmed/30675003)
To address the unmet needs for human polyclonal antibodies both as therapeutics and diagnostic reagents, building upon our previously established transchromosomic (Tc) cattle platform, we report herein ...
Shibata A, et al. Characterization of a novel reassortant H7N3 highly pathogenic avian influenza virus isolated from a poultry meat product taken on a passenger flight to Japan. J Vet Med Sci. 2019 Jan 24. Abstract
submitted by kickingbird at Jan, 26, 2019 from J Vet Med Sci. 2019 Jan 24 (via https://www.ncbi.nlm.nih.gov/pubmed/30674734)
A new reassortant H7N3 avian influenza virus (AIV) was isolated from a duck meat product that was illegally taken on board a passenger flight from China to Japan in March 2018. Sequencing analysis revealed ...
Salem E, et al. Pathogenesis, host innate immune response and aerosol transmission of Influenza D virus in cattle. J Virol. 2019 Jan 23.. Abstract
submitted by kickingbird at Jan, 26, 2019 from J Virol. 2019 Jan 23. (via https://www.ncbi.nlm.nih.gov/pubmed/30674628)
The recently discovered influenza D virus (IDV) of the Orthomyxoviridae family has been detected in swine and ruminants with a worldwide distribution. Cattle are considered to be the primary host and reservoir ...
Machkovech HM, Bloom JD, Subramaniam AR. Comprehensive profiling of translation initiation in influenza virus infected cells. PLoS Pathog. 2019 Jan 23;15(1):e1007518. Abstract
submitted by kickingbird at Jan, 26, 2019 from PLoS Pathog. 2019 Jan 23;15(1):e1007518 (via https://www.ncbi.nlm.nih.gov/pubmed/30673779)
Translation can initiate at alternate, non-canonical start codons in response to stressful stimuli in mammalian cells. Recent studies suggest that viral infection and anti-viral responses alter sites of ...
More S, et al. Long non-coding RNA PSMB8-AS1 regulates influenza virus replication. RNA Biol. 2019 Jan 22. Abstract
submitted by kickingbird at Jan, 26, 2019 from RNA Biol. 2019 Jan 22 (via https://www.ncbi.nlm.nih.gov/pubmed/30669933)
Long non-coding RNAs (lncRNAs) are a new arm of gene regulatory mechanism as discovered by sequencing techniques and follow-up functional studies. There are only few studies on lncRNAs as related to gene ...
Zhang J, et al. Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication. Virology. 2019 Jan 2;526:1-12.. Abstract
submitted by kickingbird at Jan, 23, 2019 from Virology. 2019 Jan 2;526:1-12. (via https://www.ncbi.nlm.nih.gov/pubmed/30316042)
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying JNK and PI3K ...
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