He G, Ming L, Li X, Song Y, Tang L, Ma M, Cui J, W. Genetically Divergent Highly Pathogenic Avian Influenza A(H5N8) Viruses in Wild Birds, Eastern China. Emerg Infect Dis. 2021;27(11):2940-2943. Abstract
submitted by kickingbird at Oct, 23, 2021 from Emerg Infect Dis. 2021;27(11):2940-2943 (via https://wwwnc.cdc.gov/eid/article/27/11/20-4893_article)
In late 2020, we detected 32 highly pathogenic avian influenza A(H5N8) viruses in migratory ducks in Shanghai, China. Phylogenetic analysis of 5 representative isolates identified 2 sublineages of clade ... Su W, Sia SF, Choy KT, Ji Y, Chen D, Lau EHY, Fu G. Limited onward transmission potential of reassortment genotypes from chickens co-infected with H9N2 and H7N9 avian influenza viruses. Emerg Microbes Infect. 2021 Oct 19:1-36. Abstract
submitted by kickingbird at Oct, 21, 2021 from Emerg Microbes Infect. 2021 Oct 19:1-36 (via https://pubmed.ncbi.nlm.nih.gov/34666614/)
The segmented genome of influenza A virus has conferred significant evolutionary advantages to this virus through genetic reassortment, a mechanism that facilitates the rapid expansion of viral genetic ... Mhamdi Z, Carbonneau J, Venable MC, Baz M, Abed Y,. Replication and transmission of an influenza A(H3N2) virus harboring the polymerase acidic I38T substitution, in guinea pigs. J Gen Virol. 2021 Oct;102(10). Abstract
submitted by kickingbird at Oct, 19, 2021 from J Gen Virol. 2021 Oct;102(10) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The polymerase acidic (PA) I38T substitution is a dominant marker of resistance to baloxavir. We evaluated the impact of I38T on the fitness of a contemporary influenza A(H3N2) virus. Influenza A/Switzerland/9715293/2013 ... Abolnik C, Ostmann E, Woods M, Wandrag DBR, Grewar. Experimental infection of ostriches with H7N1 low pathogenic and H5N8 clade 2.3.4.4B highly pathogenic influenza A viruses. Vet Microbiol. 2021 Oct 8;263:109251. Abstract
submitted by kickingbird at Oct, 19, 2021 from Vet Microbiol. 2021 Oct 8;263:109251 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Infection dynamics data for influenza A virus in a species is important for understanding host-pathogen interactions and developing effective control strategies. Seven-week-old ostriches challenged with ... Zhang G, Ng F, Chen M. Short-hairpin RNAs delivered by recombinant adeno-associated virus inhibited the replication of influenza A viruses in vitro. Virology. 2021 Oct 11;564:46-52. Abstract
submitted by kickingbird at Oct, 19, 2021 from Virology. 2021 Oct 11;564:46-52 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Antiviral short-hairpin RNAs (shRNAs) delivered by recombinant adeno-associated virus (rAAV) were investigated for their potential prophylactic and therapeutic applications related to the influenza A virus ... Bdeir N, Arora P, G?rtner S, P?hlmann S, Winkler M. Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activity. Sci Rep. 2021 Oct 14;11(1):20477. Abstract
submitted by kickingbird at Oct, 19, 2021 from Sci Rep. 2021 Oct 14;11(1):20477 (via https://www.nature.com/articles/s41598-021-99691-1)
Influenza A virus (IAV) infection constitutes a significant health threat. Defective interfering particles (DIPs) can arise during IAV infection and inhibit spread of wild type (WT) IAV. DIPs harbor defective ... Alqazlan N, Emam M, Nagy é, Bridle B, Sargolzaei M. Transcriptomics of chicken cecal tonsils and intestine after infection with low pathogenic avian influenza virus H9N2. Sci Rep. 2021 Oct 14;11(1):20462. Abstract
submitted by kickingbird at Oct, 19, 2021 from Sci Rep. 2021 Oct 14;11(1):20462 (via https://www.nature.com/articles/s41598-021-99182-3)
Influenza viruses cause severe respiratory infections in humans and birds, triggering global health concerns and economic burden. Influenza infection is a dynamic process involving complex biological host ... Kombiah S, Kumar M, Murugkar HV, Nagarajan S, Tosh. Role of expression of host cytokines in the pathogenesis of H9N2-PB2 reassortant and non-reassortant H5N1 avian influenza viruses isolated from crows in BALB/c mice. Microb Pathog. 2021 Oct 11;161(Pt A):105239. Abstract
submitted by kickingbird at Oct, 19, 2021 from Microb Pathog. 2021 Oct 11;161(Pt A):105239 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
The present experiment was conducted to study the role of cytokine, chemokine and TLRs responses of H9N2-PB2 reassortant H5N1 virus as compared to non-reassortant H5N1 virus isolated from crows in BALB/c ... Wang F, Wan Z, Wu J, Wang Y, Fu H, Shao H, Qian K,. A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models. Front Microbiol. 2021 Sep 27;12:730449. Abstract
submitted by kickingbird at Oct, 19, 2021 from Front Microbiol. 2021 Sep 27;12:730449 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.7304)
Neuraminidases (NAs) of H9N2 avian influenza virus (AIV) and H3N2 human seasonal influenza virus (HSIV) share similar antigenic structures. However, there are few reports on epitopes shared by these two ... Wang F, Wan Z, Wu J, Wang Y, Fu H, Shao H, Qian K,. A Cross-Reactive Monoclonal Antibody Against Neuraminidases of Both H9N2 and H3N2 Influenza Viruses Shows Protection in Mice Challenging Models. Front Microbiol. 2021 Sep 27;12:730449. Abstract
submitted by kickingbird at Oct, 16, 2021 from Front Microbiol. 2021 Sep 27;12:730449 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8503672/)
Neuraminidases (NAs) of H9N2 avian influenza virus (AIV) and H3N2 human seasonal influenza virus (HSIV) share similar antigenic structures. However, there are few reports on epitopes shared by these two ... Shibuya M, Tamiya S, Kawai A, Hirai T, Cragg MS, Y. Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza. iScience. 2021 Sep 15;24(10):103131. Abstract
submitted by kickingbird at Oct, 12, 2021 from iScience. 2021 Sep 15;24(10):103131 (via https://www.cell.com/iscience/fulltext/S2589-0042(21)01099-3)
Current influenza vaccines do not typically confer cross-protection against antigenically mismatched strains. To develop vaccines conferring broader cross-protection, recent evidence indicates the crucial ... Charman M, McFarlane S, Wojtus JK, Sloan E, Dewar. Constitutive TRIM22 Expression in the Respiratory Tract Confers a Pre-Existing Defence Against Influenza A Virus Infection. Front Cell Infect Microbiol. 2021 Sep 21;11:689707. Abstract
submitted by kickingbird at Oct, 12, 2021 from Front Cell Infect Microbiol. 2021 Sep 21;11:689707 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.6897)
The induction of antiviral effector proteins as part of a homeostatically controlled innate immune response to infection plays a critical role in limiting the propagation and transmission of respiratory ... Jia R, Jiang C, Li L, Huang C, Lu L, Xu M, Xu J, L. Interleukin 16 Enhances the Host Susceptibility to Influenza A Virus Infection. Front Microbiol. 2021 Sep 22;12:736449. Abstract
submitted by kickingbird at Oct, 12, 2021 from Front Microbiol. 2021 Sep 22;12:736449 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.7364)
Influenza A virus (IAV) is a major respiratory pathogen that causes seasonal and pandemic flu, being a threat to global health. Various viral and cellular factors have been characterized to support or ... AboElkhair MA, Hasan ME, Mousa A, Moharam I, Sulta. In-silico evidence for enhancement of avian influenza virus H9N2 virulence by modulation of its hemagglutinin (HA) antigen function and stability during co-infection with infectious bronchitis virus i. Virusdisease. 2021 Sep;32(3):548-558. Abstract
submitted by kickingbird at Oct, 12, 2021 from Virusdisease. 2021 Sep;32(3):548-558 (via https://link.springer.com/article/10.1007%2Fs13337-021-00688)
In the last few decades, frequent incidences of avian influenza (AI) H9N2 outbreaks have caused high mortality in poultry farms resulting in colossal economic losses in several countries. In Egypt, the ... Waters K, Gao C, Ykema M, Han L, Voth L, Tao YJ, W. Triple reassortment increases compatibility among viral ribonucleoprotein genes of contemporary avian and human influenza A viruses. PLoS Pathog. 2021 Oct 7;17(10):e1009962. Abstract
submitted by kickingbird at Oct, 11, 2021 from PLoS Pathog. 2021 Oct 7;17(10):e1009962 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Compatibility among the influenza A virus (IAV) ribonucleoprotein (RNP) genes affects viral replication efficiency and can limit the emergence of novel reassortants, including those with potential pandemic ... Cui H, de Jong MC, Beerens N, van Oers MM, Teng Q,. Vaccination with inactivated virus against low pathogenic avian influenza subtype H9N2 does not prevent virus transmission in chickens. J Virus Erad. 2021 Sep 22;7(3):100055. Abstract
submitted by kickingbird at Oct, 11, 2021 from J Virus Erad. 2021 Sep 22;7(3):100055 (via https://www.sciencedirect.com/science/article/pii/S205566402)
H9N2 subtype avian influenza has spread dramatically in China ever since first reported in the 1990s. A national vaccination program for poultry was initiated in 1998. Field isolation data show that the ... Wang MH, Lou J, Cao L, Zhao S, Chan RW, Chan PK, C. Characterization of key amino acid substitutions and dynamics of the influenza virus H3N2 hemagglutinin. J Infect. 2021 Oct 7:S0163-4453(21)00498-9. Abstract
submitted by kickingbird at Oct, 11, 2021 from J Infect. 2021 Oct 7:S0163-4453(21)00498-9 (via https://www.journalofinfection.com/article/S0163-4453(21)004)
The annual epidemics of seasonal influenza is partly attributed to the continued virus evolution. It is challenging to evaluate the effect of influenza virus mutations on evading population immunity. In ... Chauhan RP, Gordon ML. Deciphering transmission dynamics and spillover of avian influenza viruses from avian species to swine populations globally. Virus Genes. 2021 Oct 8:1–15. Abstract
submitted by kickingbird at Oct, 11, 2021 from Virus Genes. 2021 Oct 8:1–15 (via https://link.springer.com/article/10.1007%2Fs11262-021-01873)
Genome sequences of eleven avian influenza virus (AIV) subtypes have been reported in swine populations from seven countries until August 2020. To unravel the transmission dynamics and spillover events ... Bessière P, Figueroa T, Coggon A, Foret-Lucas C, H. Opposite outcomes of the within-host competition between highly and low pathogenic H5N8 avian influenza viruses in chickens compared to ducks. J Virol. 2021 Oct 6:JVI0136621. Abstract
submitted by kickingbird at Oct, 7, 2021 from J Virol. 2021 Oct 6:JVI0136621 (via https://journals.asm.org/doi/10.1128/JVI.01366-21)
Highly pathogenic avian influenza viruses (HPAIV) emerge from low pathogenic avian influenza viruses (LPAIV) through the introduction of basic amino acids at the hemagglutinin (HA) cleavage site. Following ... Gao J, Klenow L, Parsons L, Malik T, Phue JN, Gao. Design of the Recombinant Influenza Neuraminidase Antigen is Crucial for its Biochemical Properties and Protective Efficacy. J Virol. 2021 Oct 6:JVI0116021. Abstract
submitted by kickingbird at Oct, 7, 2021 from J Virol. 2021 Oct 6:JVI0116021 (via https://journals.asm.org/doi/10.1128/JVI.01160-21)
Supplementing influenza vaccines with recombinant neuraminidase (rNA) antigens remains a promising approach for improving the suboptimal vaccine efficacy. However, correlations among rNA designs, properties, ... 5584 items, 20/Page, Page[69/280][|<<] [|<] [61] [62] [63] [64] [65] [66] [67] [68] [69] [70] [>|] [>>|] |
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