Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Ha. Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex. Nat Commun. 2023 Apr 21;14(1):2304. Abstract
submitted by kickingbird at Apr, 24, 2023 from Nat Commun. 2023 Apr 21;14(1):2304 (via https://www.nature.com/articles/s41467-023-37911-0)
Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins ... Guo Z, He Y, Xu J, Benegal AN, Brody SL, Vahey MD. Neuraminidase Activity Modulates Cellular Coinfection during Influenza A Virus Multicycle Growth. mBio. 2023 Apr 20:e0359122. Abstract
submitted by kickingbird at Apr, 24, 2023 from mBio. 2023 Apr 20:e0359122 (via https://journals.asm.org/doi/10.1128/mbio.03591-22)
Infection of individual cells by multiple virions plays critical roles in the replication and spread of many viruses, but mechanisms that control cellular coinfection during multicycle viral growth remain ... Sun JY, Guo CY, Wang GR, Yan LT, Feng Q, Li Y, Huo. Identification of Heterophilic Epitopes of H1N1 Influenza Virus Hemagglutinin. Curr Microbiol. 2023 Apr 19;80(5):188. Abstract
submitted by kickingbird at Apr, 20, 2023 from Curr Microbiol. 2023 Apr 19;80(5):188 (via https://link.springer.com/article/10.1007/s00284-023-03294-0)
Our previous studies found that the H1-50 monoclonal antibody (mAb) of influenza A virus hemagglutinin (HA) cross-reacted with pancreatic tissue and islet β-cells, and further studies showed that H1-50 ... Daulagala P, Mann BR, Leung K, Lau EHY, Yung L, Le. Imprinted Anti-Hemagglutinin and Anti-Neuraminidase Antibody Responses after Childhood Infections of A(H1N1) and A(H1N1)pdm09 Influenza Viruses. mBio. 2023 Apr 18:e0008423. Abstract
submitted by kickingbird at Apr, 19, 2023 from mBio. 2023 Apr 18:e0008423 (via https://journals.asm.org/doi/10.1128/mbio.00084-23)
Immune imprinting is a driver known to shape the anti-hemagglutinin (HA) antibody landscape of individuals born within the same birth cohort. With the HA and neuraminidase (NA) proteins evolving at different ... Guinat C, Tang H, Yang Q, Valenzuela Agüí C, Vaugh. Bayesian phylodynamics reveals the transmission dynamics of avian influenza A(H7N9) virus at the human-live bird market interface in China. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e221. Abstract
submitted by kickingbird at Apr, 19, 2023 from Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e221 (via https://www.pnas.org/doi/10.1073/pnas.2215610120)
In 2013 to 2017, avian influenza A(H7N9) virus has caused five severe epidemic waves of human infections in China. The role of live bird markets (LBMs) in the transmission dynamics of H7N9 remains unclear. ... Lee CY, Raghunathan V, Caceres CJ, Geiger G, Seibe. Epistasis reduces fitness costs of influenza A virus escape from stem-binding antibodies. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e220. Abstract
submitted by kickingbird at Apr, 19, 2023 from Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e220 (via https://www.pnas.org/doi/10.1073/pnas.2208718120)
The hemagglutinin (HA) stem region is a major target of universal influenza vaccine efforts owing to the presence of highly conserved epitopes across multiple influenza A virus (IAV) strains and subtypes. ... Zhang H, Xie R, Zhang H, Sun R, Li S, Xia C, Li Z,. Recombinant hemagglutinin protein and DNA-RNA-combined nucleic acid vaccines harbored by yeast elicit protective immunity against H9N2 avian influenza infection. Poult Sci. 2023 Mar 20;102(6):102662.. Abstract
submitted by kickingbird at Apr, 15, 2023 from Poult Sci. 2023 Mar 20;102(6):102662. (via https://www.sciencedirect.com/science/article/pii/S003257912)
A safe, convenience, and effective vaccine for controlling avian influenza virus infection is crucial in scale poultry production. Yeasts are considered useful vaccine vehicles for the delivery of antigens, ... Lee J, Hadfield J, Black A, Sibley TR, Neher RA, B. Joint visualization of seasonal influenza serology and phylogeny to inform vaccine composition. Front Bioinform. 2023 Mar 22;3:1069487. Abstract
submitted by kickingbird at Apr, 14, 2023 from Front Bioinform. 2023 Mar 22;3:1069487 (via https://www.frontiersin.org/articles/10.3389/fbinf.2023.1069)
Seasonal influenza vaccines must be updated regularly to account for mutations that allow influenza viruses to escape our existing immunity. A successful vaccine should represent the genetic diversity ... Pellegrini F, Buonavoglia A, Omar AH, Diakoudi G,. A Cold Case of Equine Influenza Disentangled with Nanopore Sequencing. Animals (Basel). 2023 Mar 24;13(7):1153. Abstract
submitted by kickingbird at Apr, 14, 2023 from Animals (Basel). 2023 Mar 24;13(7):1153 (via https://www.mdpi.com/2076-2615/13/7/1153)
Massive sequencing techniques have allowed us to develop straightforward approaches for the whole genome sequencing of viruses, including influenza viruses, generating information that is useful for improving ... Ala U, Bajardi P, Giacobini M, Bertolotti L. Potential Impact of Environmental Pollution by Human Antivirals on Avian Influenza Virus Evolution. Animals (Basel). 2023 Mar 23;13(7):1127. Abstract
submitted by kickingbird at Apr, 14, 2023 from Animals (Basel). 2023 Mar 23;13(7):1127 (via https://www.mdpi.com/2076-2615/13/7/1127)
Antiviral (AV) drugs are the main line of defense against pandemic influenza. However, different administration policies are applied in countries with different stocks of AV drugs. These policies lead ... Bosco-Lauth A, Rodriguez A, Maison RM, Porter SM,. H7N9 influenza A virus transmission in a multispecies barnyard model. Virology. 2023 Apr 7;582:100-105. Abstract
submitted by kickingbird at Apr, 14, 2023 from Virology. 2023 Apr 7;582:100-105 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza A viruses are a diverse group of pathogens that have been responsible for millions of human and avian deaths throughout history. Here, we illustrate the transmission potential of H7N9 influenza ... Zhu Y, Wang R, Zou J, Tian S, Yu L, Zhou Y, Ran Y,. N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication. PLoS Pathog. 2023 Apr 13;19(4):e1011305. Abstract
submitted by kickingbird at Apr, 14, 2023 from PLoS Pathog. 2023 Apr 13;19(4):e1011305 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
N6-methyladenosine (m6A) modification on viral RNAs has a profound impact on infectivity. m6A is also a highly pervasive modification for influenza viral RNAs. However, its role in virus mRNA splicing ... Matsuzaki Y, Ohmiya S, Ota R, Kitai Y, Watanabe O,. Epidemiologic, clinical, and genetic characteristics of influenza C virus infections among outpatients and inpatients in Sendai, Japan from 2006 to 2020. J Clin Virol. 2023 Apr 4;162:105429. Abstract
submitted by kickingbird at Apr, 12, 2023 from J Clin Virol. 2023 Apr 4;162:105429 (via https://www.sciencedirect.com/science/article/abs/pii/S13866)
Background: Influenza C virus is a pathogen that causes acute respiratory illness in children. The clinical information about this virus is limited because of the small number of isolated viruses compared ... Kim H, Cho HK, Kang YM, Sagong M, An S, Kim S, Lee. Protective efficacy of a bivalent H5 influenza vaccine candidate against both clades 2.3.2.1 and 2.3.4.4 high pathogenic avian influenza viruses in SPF chickens. Vaccine. 2023 Apr 4:S0264-410X(23)00311-0. Abstract
submitted by kickingbird at Apr, 8, 2023 from Vaccine. 2023 Apr 4:S0264-410X(23)00311-0 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Worldwide, high pathogenic avian influenza viruses belonging to clades 2.3.4.4 and 2.3.2.1 have been circulating in both poultry and wild birds. Since 2018, Korea has built a national antigen bank to ensure ... Xu Q, Wei H, Wen S, Chen J, Lei Y, Cheng Y, Huang. Factors affecting the immunogenicity of influenza vaccines in human. BMC Infect Dis. 2023 Apr 6;23(1):211. Abstract
submitted by kickingbird at Apr, 8, 2023 from BMC Infect Dis. 2023 Apr 6;23(1):211 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
Background: The influenza viruses pose a threat to human health and medical services, and vaccination is an important way to prevent infection. However, the effectiveness of influenza vaccines is affected ... Chen M, Lyu Y, Wu F, Zhang Y, Li H, Wang R, Liu Y,. Increased public health threat of avian-origin H3N2 influenza virus caused by its evolution in dogs. Elife. 2023 Apr 6;12:e83470. Abstract
submitted by kickingbird at Apr, 7, 2023 from Elife. 2023 Apr 6;12:e83470 (via https://elifesciences.org/articles/83470)
Influenza A viruses in animal reservoirs repeatedly cross species barriers to infect humans. Dogs are the closest companion animals to humans, but the role of dogs in the ecology of influenza viruses is ... Han, S.M., Robert, A., Masuda, S. et al. Transmission dynamics of seasonal influenza in a remote island population. Sci Rep . 2023 Apr 3;13(1):5393. Abstract
submitted by kickingbird at Apr, 6, 2023 from Sci Rep . 2023 Apr 3;13(1):5393 (via https://www.nature.com/articles/s41598-023-32537-0)
Seasonal influenza outbreaks remain an important public health concern, causing large numbers of hospitalizations and deaths among high-risk groups. Understanding the dynamics of individual transmission ... Pohlmann A, Stejskal O, King J, Bouwhuis S, Packmo. Mass mortality among colony-breeding seabirds in the German Wadden Sea in 2022 due to distinct genotypes of HPAIV H5N1 clade 2.3.4.4b. J Gen Virol. 2023 Apr;104(4).. Abstract
submitted by kickingbird at Apr, 6, 2023 from J Gen Virol. 2023 Apr;104(4). (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Mass mortality was observed among colony-breeding seabirds in the German Wadden Sea area of the North Sea during the summer months of 2022. Several species' colonies were affected, most notably sandwich ... Liu M, van Kuppeveld FJ, de Haan CA, de Vries E. Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors. Curr Opin Virol. 2023 Mar 29;60:101314. Abstract
submitted by kickingbird at Apr, 3, 2023 from Curr Opin Virol. 2023 Mar 29;60:101314 (via https://www.sciencedirect.com/science/article/pii/S187962572)
Influenza A viruses (IAVs) originating from animal reservoirs pose continuous threats to human health as demonstrated by the Spanish flu pandemic. Infection starts by attachment to host receptors, a crucial ... Zhao B, Wang W, Song Y, Wen X, Feng S, Li W, Ding. Genetic characterization and pathogenicity of H7N9 highly pathogenic avian influenza viruses isolated from South China in 2017. Front Microbiol. 2023 Mar 7;14:1105529. Abstract
submitted by kickingbird at Apr, 1, 2023 from Front Microbiol. 2023 Mar 7;14:1105529 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1105)
Since 2017, the new H7N9 highly pathogenic avian influenza viruses (HPAIVs) have been responsible for more than 200,000 cases of chicken infection and more than 120,000 chicken deaths in China. Our previous ... 5584 items, 20/Page, Page[42/280][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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