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2026-8-11 0:32:54
Article

Ahlstrom, C.A., Scott, L.C., Reeves, A.B. et al. Ecological shifts in avian influenza viruses following HPAIV introductions in southwestern Alaska, 2011-2024. npj Viruses (2026).  Abstract  
submitted by kickingbird at Jul, 18, 2026 from npj Viruses (2026) (via https://www.nature.com/articles/s44298-026-00212-6)
Southwestern Alaska wetlands are critical staging habitats for migratory waterfowl that breed in western North America and East Asia. Since 2011, samples originating from hunter-harvested waterfowl and ...

Brock N, Zeng H, Pappas C, Kieran TJ, Sun X, Pulit. Cellular tropism of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b viruses in human respiratory and bovine mammary epithelial cells. Microbiol Spectr 0:e01377-26.  Abstract  
submitted by kickingbird at Jul, 18, 2026 from Microbiol Spectr 0:e01377-26 (via https://journals.asm.org/doi/10.1128/spectrum.01377-26)
The recent introduction and spread of HPAI A(H5N1) clade 2.3.4.4b viruses to U.S. dairy cattle demonstrate their ability to adapt to new mammalian hosts. Although multiple A(H5N1) genotypes have caused ...

Prantner D, Qi X, Villaneuva LM, Paton J, Blanco J. The signaling adaptor insulin receptor substrate 2 (IRS2) limits lethal host responses induced by influenza infection. Innate Immun. 2026 Jan-Dec;32:17534259261469305.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Innate Immun. 2026 Jan-Dec;32:17534259261469305 (via https://journals.sagepub.com/doi/10.1177/17534259261469305)
Influenza is a highly contagious virus with most individuals showing recovery within a week after symptom onset. However, children, the elderly, and those with chronic health conditions are at high risk ...

Da Silva K, Naffakh N, Rameix-Welti MA, Lemoine F. Accounting for Defective Viral Genomes in viral consensus genome reconstruction, application to influenza virus. PLoS Comput Biol. 2026 Jul 16;22(7):e1014115.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from PLoS Comput Biol. 2026 Jul 16;22(7):e1014115 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
In the context of viral epidemic surveillance, generating accurate consensus viral genomes from sequencing data is critical for tracking the emergence of mutations of concern, evaluating the genomic diversity ...

Chen Y, Ankerhold J, Jia T, Wolkewitz M, Fuchs J,. Autoantibodies against type I interferons in patients with zoonotic H7N9 influenza: an observational case-control study. EBioMedicine. 2026 Jul 16;130:106387.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from EBioMedicine. 2026 Jul 16;130:106387 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The determinants of the species barrier preventing human infections with avian influenza A viruses (IAV) are incompletely understood. We previously identified loss-of-function variants of the ...

Han Yan, etc.,al. [preprint]Antibodies against influenza A/H1N1pdm2009 and B/Victoria strains but not A/H3N2 are increased in recent onset type 1 narcolepsy versus matched controls. https://doi.org/10.64898/2026.06.13.26355596.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from https://doi.org/10.64898/2026.06.13.26355596 (via https://www.medrxiv.org/content/10.64898/2026.06.13.26355596)
Study Objectives Onsets of Narcolepsy type-1 (NT1) increased following A/H1N1 vaccination with Pandemrix? in Europe and with A/H1N1pdm2009 infections in China and other countries. To test if other strains ...

Ciminski K, Reuther P, Rijkers R, de Vries RP, Sch. The receptor landscape of influenza A viruses. J Virol 0:e01443-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e01443-25 (via https://journals.asm.org/doi/10.1128/jvi.01443-25)
Influenza A viruses (IAVs) have a remarkable ability to adapt to new host species, which has been attributed to the specificity of the viral hemagglutinin (HA) for sialylated glycans and the functional ...

Shirazi R, Kim SY, Cruz A, Stumpff JP, Sveiven SN,. RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cells. J Virol 0:e02225-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e02225-25 (via https://journals.asm.org/doi/10.1128/jvi.02225-25)
Beyond a physical barrier, the lung epithelium provides an essential line of defense against infectious pathogens, such as influenza A viruses (IAVs), by producing antimicrobial factors and triggering ...

Kubacki J, Renzullo S, Miller-Collmann N, Lale D,. Genome sequence of a Florida Clade 1 case of equine influenza in Switzerland. Microbiol Resour Announc 0:e00635-26.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Microbiol Resour Announc 0:e00635-26 (via https://journals.asm.org/doi/10.1128/mra.00635-26)
Here, we report the whole-genome sequence of A/Equus caballus/Zuerich/260760/2026, an equine influenza virus (H3N8) belonging to Florida Clade 1, detected in Switzerland following increased reports of ...

Snyder CA, Janzen GM, Zanella GC, Moraes DCA, Silv. Occupationally Exposed and General Population Antibody Profiles to Influenza A Viruses Circulating in Swine as Indication of Zoonotic Risk. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1995_article)
Persons with occupational exposure to swine might be at disproportionate risk for zoonotic swine influenza A virus. To evaluate human antibody responses, we tested serum or plasma from swine veterinarian, ...

Seger H, Baker AL, Buckley AC, Anderson TK, Markin. Detection of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Genotype D1.2 Virus in Swine after Experimental Inoculation. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1765_article)
Highly pathogenic avian influenza H5NX clade 2.3.4.4b viruses continue to circulate globally. Reintroduction of Eurasian lineage viruses into North America and reassortment with endemic low pathogenicity ...

Pyles, K., Darling, T.L., Huang, LC. et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. npj Vaccines (2026).  Abstract  
submitted by kickingbird at Jul, 15, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01523-8)
The emergence of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in dairy cows and transmission to humans has heightened public health concerns. In this work, we characterized the immunogenicity ...

Jiahao Zhang, Huaiyuan Cai, Tingting Man, Lihong H. Heterogeneous viral-host response at single-cell resolution and viral adaptive mutational atlas in birds and mammals upon H5 influenza virus infection. National Science Review, 2026;, nwag380.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from National Science Review, 2026;, nwag380 (via https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr)
H5 highly pathogenic avian influenza viruses (HPAIVs) are prevalent in birds, causing infection in over 60 mammalian species worldwide. However, species-specific viral-host response at the single-cell ...

Ren Y, Li H, Yan W, Liu X, Chi W, Luo R, Stoeger T. Novel Reassortant H9N2 Avian Influenza Viruses with Dual Receptor-Binding Capacity and Evidence of Direct Mammalian Infectivity Circulating in Northeast China Live Poultry Markets. Viruses. 2026; 18(7):771.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Viruses. 2026; 18(7):771 (via https://www.mdpi.com/1999-4915/18/7/771)
H9N2 low-pathogenic avian influenza viruses (LPAIV) represent an ongoing zoonotic threat due to their enzootic circulation in poultry, reassortment capacity, and increasing human transmission events. This ...

Li, Z. et al. (2027). A Unified Benchmark and Conditional Sequence Modeling Framework for Future Influenza Evolution Prediction. ISBRA 2026. Lecture Notes in Computer Science.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from ISBRA 2026. Lecture Notes in Computer Science (via https://link.springer.com/chapter/10.1007/978-981-92-3716-6_)
Vaccination remains the most effective strategy for seasonal influenza prevention, but vaccine strain selection depends on anticipating future circulating variants before they are fully observed. This ...

Takadate Y, Nishiura H, Kumagai A, Mine J, Tsuneku. High pathogenicity avian influenza A (H5N1) viruses isolated from poultry and wild birds in Japan during the 2024-2025 season. Microbiol Spectr. 2026 Jul 14:e0029326.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Microbiol Spectr. 2026 Jul 14:e0029326 (via https://journals.asm.org/doi/10.1128/spectrum.00293-26)
H5N1 high pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4b continue to spread globally among wild birds and poultry, and diversify through gene reassortment. Since 2024, spillovers of H5N1 ...

Zhang, X., Tang, Q., Zhang, Y. et al. Divergent pathogenic mechanisms of influenza A and influenza B viruses. Arch Microbiol 208, 476 (2026).  Abstract  
submitted by kickingbird at Jul, 13, 2026 from Arch Microbiol 208, 476 (2026) (via https://link.springer.com/article/10.1007/s00203-026-05032-z)
Seasonal influenza in humans is predominantly caused by influenza A virus (IAV) and influenza B virus (IBV), but they differ markedly in host range, evolutionary dynamics, and pandemic potential. Such ...

Kasianov N, Sharshov K, Derko A, Dubovitskiy N, Mi. Long-Term Monitoring of Influenza A Viruses in Wild Waterfowl: Evidence from the Lake Baikal Basin (2018–2024). Viruses. 2026; 18(7):761.  Abstract  
submitted by kickingbird at Jul, 13, 2026 from Viruses. 2026; 18(7):761 (via https://www.mdpi.com/1999-4915/18/7/761)
Wild waterfowl constitute the primary natural reservoir of influenza A viruses, and wetlands at the convergence of major migratory flyways serve as critical hubs for viral genetic exchange. Baikal Siberia, ...

Fernanda Sánchez-Rodríguez, etc.,al. Highly Pathogenic Avian Influenza H5N1 in South America, 2022–2025: Spread, Affected Species, and Southward Expansion into the Antarctic Region. Viruses 2026, 18(7), 764.  Abstract  
submitted by kickingbird at Jul, 13, 2026 from Viruses 2026, 18(7), 764 (via https://www.mdpi.com/1999-4915/18/7/764)
The H5N1 highly pathogenic avian influenza (HPAI) virus has caused severe global losses, reaching South America in 2022 and Antarctica in 2024. Here, we synthesize outbreak reports submitted to the World ...

Jeong-Hyun Nam, etc.,al. Cross-neutralization of Korea H5N1 clade 2.3.4.4b isolates using the WHO candidate vaccine virus-derived ferret antisera. Vaccine: X.  Abstract  
submitted by kickingbird at Jul, 13, 2026 from Vaccine: X (via https://www.sciencedirect.com/science/article/pii/S259013622)
Recent infections and transmissions of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses in humans and animals pose a significant global public health threat. Vaccination is the most ...

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