Zu S, Xue Q, He Z, et al. Duck PIAS2 Promotes H5N1 Avian Influenza Virus Replication Through Its SUMO E3 Ligase Activity. Front Microbiol. 2020;11:1246. Abstract
submitted by kickingbird at Jun, 30, 2020 from Front Microbiol. 2020;11:1246 (via https://pubmed.ncbi.nlm.nih.gov/32595623/)
The protein inhibitor of the activated STAT2 (PIAS2) has been implicated in many cellular processes and can also regulate viral replication in mammals. However, the role of PIAS2 in the highly pathogenic ...
McCuen MM, Pitesky ME, Buler JJ, et al. A Comparison of Amplification Methods to Detect Avian Influenza Viruses in California Wetlands Targeted via Remote Sensing of Waterfowl. Transbound Emerg Dis. 2020;10.1111/tbed.13612. Abstract
submitted by kickingbird at Jun, 30, 2020 from Transbound Emerg Dis. 2020;10.1111/tbed.13612 (via https://pubmed.ncbi.nlm.nih.gov/32592444/)
Migratory waterfowl, including geese and ducks, are indicated as the primary reservoir of avian influenza viruses (AIv) which can be subsequently spread to commercial poultry. The US Department of Agriculture's ...
Zhang Y, Zhang HX, Zheng Q. In Silico Study of Membrane Lipid Composition Regulating Conformation and Hydration of Influenza Virus B M2 Channel. J Chem Inf Model. 2020;10.1021/acs.jcim.0c00329. Abstract
submitted by kickingbird at Jun, 27, 2020 from J Chem Inf Model. 2020;10.1021/acs.jcim.0c00329 (via https://pubmed.ncbi.nlm.nih.gov/32589410/)
The proton conduction of transmembrane influenza virus B M2 (BM2) proton channel is possibly mediated by the membrane environment, but the detailed molecular mechanism is challenging to determine. In this ...
Hao W, Wang L, Li S. FKBP5 Regulates RIG-I-Mediated NF-κB Activation and Influenza A Virus Infection. Viruses. 2020;12(6):E672. Abstract
submitted by kickingbird at Jun, 26, 2020 from Viruses. 2020;12(6):E672 (via https://pubmed.ncbi.nlm.nih.gov/32580383/)
Influenza A virus (IAV) is a highly transmissible respiratory pathogen and is a constant threat to global health with considerable economic and social impact. Influenza viral RNA is sensed by host pattern ...
Giotis ES. Inferring the Urban Transmission Potential of Bat Influenza Viruses. Front Cell Infect Microbiol. 2020;10:264. Abstract
submitted by kickingbird at Jun, 26, 2020 from Front Cell Infect Microbiol. 2020;10:264 (via https://pubmed.ncbi.nlm.nih.gov/32582567/)
Bats are considered natural reservoirs of various, potentially zoonotic viruses, exemplified by the influenza A-like viruses H17N10 and H18N11 in asymptomatic Neotropical bats. These influenza viruses ...
Lin RJ, Huang CH, Liu PC, et al. Zinc Finger Protein ZFP36L1 Inhibits Influenza A Virus Through Translational Repression by Targeting HA, M and NS RNA Transcripts. Nucleic Acids Res. 2020;gkaa458. Abstract
submitted by kickingbird at Jun, 25, 2020 from Nucleic Acids Res. 2020;gkaa458 (via https://pubmed.ncbi.nlm.nih.gov/32556261/)
ZFP36L1, a CCCH-type zinc finger protein, is an RNA-binding protein that participates in controlling cellular mRNA abundance and turnover by posttranscriptional regulation. Here, we demonstrated that ZFP36L1 ...
Wu NC, Thompson AJ, Lee JM, et al. Different Genetic Barriers for Resistance to HA Stem Antibodies in Influenza H3 and H1 Viruses. Science. 2020;368(6497):1335-1340. Abstract
submitted by kickingbird at Jun, 25, 2020 from Science. 2020;368(6497):1335-1340 (via https://pubmed.ncbi.nlm.nih.gov/32554590/)
The discovery and characterization of broadly neutralizing human antibodies (bnAbs) to the highly conserved stem region of influenza hemagglutinin (HA) have contributed to considerations of a universal ...
Qin Z, Qu X, Lei L, Xu L, Pan Z. Y-Box-Binding Protein 3 (YBX3) Restricts Influenza A Virus by Interacting With Viral Ribonucleoprotein Complex and Imparing Its Function. J Gen Virol. 2020;101(4):385-398.. Abstract
submitted by kickingbird at Jun, 25, 2020 from J Gen Virol. 2020;101(4):385-398. (via https://pubmed.ncbi.nlm.nih.gov/32553055/)
The influenza A virus (IAV) ribonucleoprotein (vRNP) complex consists of polymerase subunits, nucleoprotein (NP) and viral RNA and is responsible for RNA transcription and replication. Interactions between ...
Sun N, Jiang L, Ye M, et al. TRIM35 Mediates Protection Against Influenza Infection by Activating TRAF3 and Degrading Viral PB2. Protein Cell. 2020;10.1007/s13238-020-00734-6. Abstract
submitted by kickingbird at Jun, 25, 2020 from Protein Cell. 2020;10.1007/s13238-020-00734-6 (via https://pubmed.ncbi.nlm.nih.gov/32562145/)
Tripartite motif (TRIM) family proteins are important effectors of innate immunity against viral infections. Here we identified TRIM35 as a regulator of TRAF3 activation. Deficiency in or inhibition of ...
Podshivalov DD, Kirilin EM, Konnov SI, ?vedas VK. Structural Organization and Dynamic Characteristics of the Binding Site for Conformational Rearrangement Inhibitors in Hemagglutinins From H3N2 and H7N9 Influenza Viruses. Biochemistry (Mosc). 2020;85(4):499-506. Abstract
submitted by kickingbird at Jun, 25, 2020 from Biochemistry (Mosc). 2020;85(4):499-506 (via https://pubmed.ncbi.nlm.nih.gov/32569557/)
Computer models of hemagglutinins from the H3N2 and H7N9 influenza viruses were developed to study structural organization and dynamic characteristics of the binding site for the conformational rearrangement ...
Bhat S, Bialy D, Sealy JE, Sadeyen JR, Chang P, Iq. A Ligation and Restriction Enzyme Independent Cloning Technique: An Alternative to Conventional Methods for Cloning Hard-To-Clone Gene Segments in the Influenza Reverse Genetics System. Virol J. 2020;17(1):82. Abstract
submitted by kickingbird at Jun, 25, 2020 from Virol J. 2020;17(1):82 (via https://pubmed.ncbi.nlm.nih.gov/32576218/)
Background: Reverse genetics is used in many laboratories around the world and enables the creation of tailor-made influenza viruses with a desired genotype or phenotype. However, the process is not flawless, ...
Zhao XN, Zhang HJ, Li D, et al. Whole-genome Sequencing Reveals Origin and Evolution of Influenza A(H1N1)pdm09 Viruses in Lincang, China, From 2014 to 2018. PLoS One. 2020;15(6):e0234869. Abstract
submitted by kickingbird at Jun, 25, 2020 from PLoS One. 2020;15(6):e0234869 (via https://pubmed.ncbi.nlm.nih.gov/32579578/)
The continuous variation of the seasonal influenza viruses, particularly A(H1N1)pdm09, persistently threatens human life and health around the world. In local areas of southwest china, the large time-scale ...
Dinev I, Zarkov I, Goujgoulova GV, Stoimenov GM, G. Pathologic Evaluation of Influenza A H5N8 Infection Outbreaks in Mule Ducks in Bulgaria. Avian Dis. 2020;64(2):203-209.. Abstract
submitted by kickingbird at Jun, 19, 2020 from Avian Dis. 2020;64(2):203-209. (via https://pubmed.ncbi.nlm.nih.gov/32550621/)
This article outlines pathomorphologic findings of a study involving commercial mule ducks with confirmed influenza A H5N8 infections after a series of outbreaks in Bulgaria. Examinations were carried ...
Stephens CB, Spackman E, Pantin-Jackwood MJ. Effects of an H7 Highly Pathogenic and Related Low Pathogenic Avian Influenza Virus on Chicken Egg Production, Viability, and Virus Contamination of Egg Contents and Surfaces. Avian Dis. 2020;64(2):143-148. Abstract
submitted by kickingbird at Jun, 19, 2020 from Avian Dis. 2020;64(2):143-148 (via https://pubmed.ncbi.nlm.nih.gov/32550614/)
Both highly pathogenic (HP) and low pathogenic (LP) avian influenza virus (AIV) can cause decreases or even cessation of egg production in chickens and turkeys. Production of abnormal eggs (deformed, thin-shelled, ...
Cerda-Armijo C, de León MB, Ruvalcaba-Ortega I, et. High Prevalence of Avian Influenza Virus Among Wild Waterbirds and Land Birds of Mexico. Avian Dis. 2020;64(2):135-142. Abstract
submitted by kickingbird at Jun, 19, 2020 from Avian Dis. 2020;64(2):135-142 (via https://pubmed.ncbi.nlm.nih.gov/32550613/)
Aquatic wild birds, especially waterfowl, have been long considered the main reservoirs of the avian influenza A virus; however, recent surveys have found an important prevalence of these viruses among ...
Tindale LC, Baticados W, Duan J, et al. Extraction and Detection of Avian Influenza Virus From Wetland Sediment Using Enrichment-Based Targeted Resequencing. Front Vet Sci. 2020;7:301. Abstract
submitted by kickingbird at Jun, 19, 2020 from Front Vet Sci. 2020;7:301
Early virus detection and characterization is key to successful avian influenza virus (AIV) surveillance for the health of humans as well as domestic poultry. We explored a novel sampling approach and ...
Wang J, Cen S. Roles of lncRNAs in Influenza Virus Infection. Emerg Microbes Infect. 2020;1-22.. Abstract
submitted by kickingbird at Jun, 19, 2020 from Emerg Microbes Infect. 2020;1-22. (via https://pubmed.ncbi.nlm.nih.gov/32543285/)
Recent studies have identified host long noncoding RNAs (lncRNAs) as key regulators of host-virus interactions during viral infection. The influenza A virus (IAV) remains a serious threat to public health ...
Du Y, Yang F, Wang Q, et al. Influenza a Virus Antagonizes Type I and Type II Interferon Responses via SOCS1-dependent Ubiquitination and Degradation of JAK1. Virol J. 2020;17(1):74. Abstract
submitted by kickingbird at Jun, 16, 2020 from Virol J. 2020;17(1):74 (via https://pubmed.ncbi.nlm.nih.gov/32532301/)
Background: Although influenza A virus (IAV) employs diverse strategies to evade IFN responses by inhibiting the synthesis of IFN, how IAV regulates signaling downstream of IFN is incompletely understood. ...
Mosad SM, El-Gohary FA, Ali HS, El-Sharkawy H, Elm. Pathological and Molecular Characterization of H5 Avian Influenza Virus in Poultry Flocks From Egypt Over a Ten-Year Period (2009-2019). Animals (Basel). 2020;10(6):E1010. Abstract
submitted by kickingbird at Jun, 13, 2020 from Animals (Basel). 2020;10(6):E1010 (via https://pubmed.ncbi.nlm.nih.gov/32527004)
Avian influenza virus (AIV) remains one of the enzootic zoonotic diseases that challenges the poultry industry in Egypt. In the present study, a total of 500 tissue samples were collected from 100 chicken ...
Yang H, Carney PJ, Chang JC, Stevens J. Molecular Characterization and Three-Dimensional Structures of Avian H8, H11, H14, H15 and Swine H4 Influenza Virus Hemagglutinins. Heliyon. 2020;6(6):e04068.. Abstract
submitted by kickingbird at Jun, 13, 2020 from Heliyon. 2020;6(6):e04068. (via https://pubmed.ncbi.nlm.nih.gov/32529072)
Of the eighteen hemagglutinin (HA) subtypes (H1-H18) that have been identified in bats and aquatic birds, many HA subtypes have been structurally characterized. However, several subtypes (H8, H11 and H12) ...
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