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2026-2-12 8:04:11
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Li H, Yan W, Liu X, Gao B, Peng J, Jiang F, Cui Q,. Emergence and Phylodynamics of Influenza D Virus in Northeast China Reveal Sporadic Detection and Predominance of the D/Yamagata/2019 Lineage in Cattle. Viruses. 2026; 18(1):93.  Abstract  
submitted by kickingbird at Jan, 15, 2026 from Viruses. 2026; 18(1):93 (via https://www.mdpi.com/1999-4915/18/1/93)
Influenza D virus (IDV), an emerging orthomyxovirus with zoonotic potential, infects diverse hosts, causes respiratory disease, and remains poorly characterized in China despite its global expansion. From ...

Gioula G, Exindari M. The Airway Microbiome as a Modulator of Influenza Virus Infection: Mechanistic Insights and Translational Perspectives-Review. Pathogens. 2026; 15(1):63.  Abstract  
submitted by kickingbird at Jan, 15, 2026 from Pathogens. 2026; 15(1):63 (via https://www.mdpi.com/2076-0817/15/1/63)
Outcomes of influenza virus infection vary widely across individuals, reflecting not only viral genetics and host factors but also the composition and function of the airway microbiome. Over the past few ...

Mironenko A, Muzyka N, Teteriuk N, Radchenko L, Po. Genetic Characterization of Avian Influenza Virus A (H1N1) Isolated from a Fieldfare Turdus pilaris in Ukraine. Microbiology Research. 2026; 17(1):19.  Abstract  
submitted by kickingbird at Jan, 15, 2026 from Microbiology Research. 2026; 17(1):19 (via https://www.mdpi.com/2036-7481/17/1/19)
Avian influenza viruses are predominantly associated with waterfowl and shorebirds, and are rarely detected in other avian hosts in nature. In 2021, an H1N1 virus was isolated from a Fieldfare Turdus pilaris ...

Agerlin, M.V., Larsen, L.E., Weber, N.R. et al. Influenza A virus infection dynamics in two sow herds and effects of interventions. Porc Health Manag (2026).  Abstract  
submitted by kickingbird at Jan, 15, 2026 from Porc Health Manag (2026) (via https://link.springer.com/article/10.1186/s40813-025-00481-2)
BackgroundThe epidemiology of swine influenza A virus (swIAV) has undergone a change from causing mainly epidemic infections to continuous endemic circulation within herds. Several studies have traced ...

Brittany A Seibert, etc.,al. [preprint]Trimester-Dependent Vertical Transmission of H5N1 Influenza Virus Through Placental and Mammary Routes Impairs Offspring Development. https://doi.org/10.1101/2025.07.07.663583.  Abstract  
submitted by kickingbird at Jan, 14, 2026 from https://doi.org/10.1101/2025.07.07.663583 (via https://www.biorxiv.org/content/10.1101/2025.07.07.663583v4)
Avian influenza H5N1 has pandemic potential and historically has caused more severe disease in pregnant women than the general population. With increasing transmission of H5N1 detected among placental ...

Butt, S.L., de Oliveira, P.S.B., Rani, R. et al. Novel recombinant H5-based vaccine provides effective protection against H5N1 influenza virus in cats. npj Vaccines (2026).  Abstract  
submitted by kickingbird at Jan, 13, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-025-01369-6)
The emergence and broad circulation of highly pathogenic avian influenza (HPAI) H5N1 virus in wild birds and its spillover into dairy cows with sustained transmission in this species pose a major risk ...

Caputo V, Libera M, Campos Mota Y, Nagashima K, Mo. Extended Heterosubtypic Neutralization and Preclinical Model In Vivo Protection from Clade 2.3.4.4b H5 Influenza Virus Infection by Broadly Neutralizing Antibodies. Vaccines. 2026; 14(1):71.  Abstract  
submitted by kickingbird at Jan, 12, 2026 from Vaccines. 2026; 14(1):71 (via https://www.mdpi.com/2076-393X/14/1/71)
Background/Objective: The influenza virus remains one of the most prevalent respiratory pathogens, posing significant global health and economic challenges. According to the World Health Organization, ...

Giselle GK Ng, etc.,al. [preprint]Haemagglutinin 162-164 deletions enhance influenza B/Victoria virus fitness and virulence in vivo. https://doi.org/10.64898/2026.01.08.698527.  Abstract  
submitted by kickingbird at Jan, 11, 2026 from https://doi.org/10.64898/2026.01.08.698527 (via https://www.biorxiv.org/content/10.64898/2026.01.08.698527v1)
Influenza B viruses cause substantial respiratory disease and seasonal outbreaks. Despite decades of circulation in humans, only the B/Victoria lineage persisted after the COVID-19 pandemic. Continual ...

Zhu, W., Xu, Z., Wang, X., Li, X., Li, Z., Dong, G. Low-replication influenza virus mediates high pathogenicity through an inflammation-driven lung-heart-brain axis in mice. Emerging Microbes & Infections, 15(1).  Abstract  
submitted by kickingbird at Jan, 10, 2026 from Emerging Microbes & Infections, 15(1) (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The outcomes of viral infections typically correlate with viral load in host tissues. In this study, we identified a H3N2 strain A/Environment/Guangxi/44461/2019 (GX19) that induced rapid mortality in ...

Ibrahim, M., Said, A., Wahba, M. A., & Yehia, N. Genetic and antigenic analysis of the highly pathogenic avian influenza H5N8 virus clade 2.3.4.4b isolated from waterfowl in Egypt during 2022; evidence of brain-specific HA mutations. British Poultry Science, 1–10.  Abstract  
submitted by kickingbird at Jan, 10, 2026 from British Poultry Science, 1–10 (via https://www.tandfonline.com/doi/full/10.1080/00071668.2025.2)
1. This study characterised the H5N8 highly pathogenic avian influenza (HPAI) viruses, clade 2.3.4.4b from backyard waterfowl selected from Menoufia governorate during 2022. Genetic and antigenic analysis ...

Myint AP, Shirreff G, Baillie V, Bal A, Boutros CF. Association of influenza viral genetic information with severity markers in patients hospitalised with influenza: multicentre retrospective cohort study. BMJ Open. 2026 Jan 8;16(1):e111643.  Abstract  
submitted by kickingbird at Jan, 10, 2026 from BMJ Open. 2026 Jan 8;16(1):e111643 (via https://bmjopen.bmj.com/content/16/1/e111643)
Objective: The objective of this study was to determine the association between viral subtype/clade and disease severity.Design: Multicentre retrospective cohort study.Setting: This study used data from ...

Wu SX, Davis CN, Arnold M, Tildesley MJ. The role of ducks in detecting Highly Pathogenic Avian Influenza in small-scale backyard poultry farms. PLoS Comput Biol. 2026 Jan 9;22(1):e1013357.  Abstract  
submitted by kickingbird at Jan, 10, 2026 from PLoS Comput Biol. 2026 Jan 9;22(1):e1013357 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Previous research efforts on highly pathogenic H5N1 avian influenza (HPAI) suggest that different avian species exhibit a varied severity of clinical signs after infection. Waterfowl, such as ducks or ...

Adachi, K., Handharyani, E., Ueno, S. Tsukamoto Y. Comparative Hemagglutination of Avian Influenza A/H5N1 Viruses by Erythrocytes from Ostrich, Emu, Japanese Quail, Chicken and Horse. Open Journal of Veterinary Medicine, 16, 1-15.  Abstract  
submitted by kickingbird at Jan, 9, 2026 from Open Journal of Veterinary Medicine, 16, 1-15 (via https://www.scirp.org/journal/paperinformation?paperid=14855)
Influenza A viruses initiate infection when the envelope glycoprotein hemagglutinin (HA) binds sialic?acid-containing receptors on host cells and mediates membrane fusion. HA?mediated cross?linking of ...

Jenny J. Ahn, etc.,al. [preprint]Influenza hemagglutinin subtypes have different sequence constraints despite sharing extremely similar structures. https://doi.org/10.64898/2026.01.05.697808.  Abstract  
submitted by kickingbird at Jan, 9, 2026 from https://doi.org/10.64898/2026.01.05.697808 (via https://www.biorxiv.org/content/10.64898/2026.01.05.697808v1)
Hemagglutinins (HA) from different influenza A virus subtypes share as little as ~40% amino acid identity, yet their protein structure and cell entry function are highly conserved. Here we examine the ...

Mei M, Zhang X, Wu Q, Xu M, Zhao Y. Virulence and transmission characteristic of H3N8 avian influenza virus circulating in chickens in China. Virulence. 2026 Jan 7:2613516.  Abstract  
submitted by kickingbird at Jan, 9, 2026 from Virulence. 2026 Jan 7:2613516 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2026.2)
Influenza H3N8 viruses have been frequently isolated from chicken farms. However, comprehensive characterization of their virological properties, molecular evolution, virulence, and risk of spillover into ...

Lucas M. Ferreri, etc.,al. [preprint]Within-host adaptive evolution is limited by genetic drift in experimental human influenza A virus infections. https://doi.org/10.64898/2026.01.07.698006.  Abstract  
submitted by kickingbird at Jan, 9, 2026 from https://doi.org/10.64898/2026.01.07.698006 (via https://www.biorxiv.org/content/10.64898/2026.01.07.698006v1)
Selection of advantageous mutations drives the emergence of dominant variants during seasonal influenza epidemics. However, within-host detection of such variants remains rare, limiting our understanding ...

Claudia Trombetta, etc.,al. [preprint]Serological investigation of influenza D virus in cats and dogs in Europe. https://doi.org/10.64898/2026.01.03.697426.  Abstract  
submitted by kickingbird at Jan, 9, 2026 from https://doi.org/10.64898/2026.01.03.697426 (via https://www.biorxiv.org/content/10.64898/2026.01.03.697426v1)
A multicentric European study investigated the seroprevalence of influenza D virus (IDV) in domestic cats and dogs. Serum samples from Italy, France and Ukraine (2015-2018, 2020, 2023- 2024) showed no ...

Ishida, H., Murakami, H., Mizuno, S. et al. Development of an influenza D virus with an eight- or nine-segment genome. Sci Rep (2026).  Abstract  
submitted by kickingbird at Jan, 9, 2026 from Sci Rep (2026) (via https://link.springer.com/article/10.1038/s41598-025-34838-y)
Influenza D virus (IDV) contains seven genome segments. The M and NS segments are regulated via splicing to express two proteins each (P42 and M1 from the M segment and NS1 and NS2 from the NS segment). ...

Jiaojiao Liu, etc.,al. [preprint]Antibodies elicited by the 2025-2026 influenza vaccine in humans. https://doi.org/10.64898/2026.01.05.26343449.  Abstract  
submitted by kickingbird at Jan, 8, 2026 from https://doi.org/10.64898/2026.01.05.26343449 (via https://www.medrxiv.org/content/10.64898/2026.01.05.26343449)
A new H3N2 variant (named subclade K) possesses several key hemagglutinin substitutions and is circulating widely during the 2025-2026 influenza season. In this report, we completed experiments to determine ...

Natalie N Tarbuck, etc.,al. [preprint]Natural H5N1 immunity in dairy cows is durable and cross-protective but non-sterilizing. https://doi.org/10.64898/2026.01.06.697911.  Abstract  
submitted by kickingbird at Jan, 8, 2026 from https://doi.org/10.64898/2026.01.06.697911 (via https://www.biorxiv.org/content/10.64898/2026.01.06.697911v1)
Ongoing transmission of influenza A virus (H5N1) in U.S. dairy cattle threatens both animal and human health, underscoring the need to understand the durability of host immunity against reinfection with ...

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