Valerie Le Sage, etc.,al. [preprint]Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus. https://doi.org/10.1101/2024.10.23.619881. Abstract
submitted by kickingbird at Oct, 25, 2024 from https://doi.org/10.1101/2024.10.23.619881 (via https://www.biorxiv.org/content/10.1101/2024.10.23.619881v1)
The emergence of highly pathogenic H5N1 avian influenza in dairy cattle herds across the United States has caused multiple mild human infections. There is an urgent need to understand the risk of spillover ... Bendall EE, Zhu Y, Fitzsimmons WJ, Rolfes M, Melli. Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons. Virus Evol. 2024 Oct 3;10(1):veae084. Abstract
submitted by kickingbird at Oct, 25, 2024 from Virus Evol. 2024 Oct 3;10(1):veae084 (via https://academic.oup.com/ve/article/10/1/veae084/7808531)
While influenza A virus (IAV) antigenic drift has been documented globally, in experimental animal infections, and in immunocompromised hosts, positive selection has generally not been detected in acute ... Di Y, Zhang C, Ren Z, Jiang R, Tang J, Yang S, Wan. The self-assembled nanoparticle-based multi-epitope influenza mRNA vaccine elicits protective immunity against H1N1 and B influenza viruses in mice. Front Immunol. 2024 Oct 8;15:1483720. Abstract
submitted by kickingbird at Oct, 25, 2024 from Front Immunol. 2024 Oct 8;15:1483720 (via https://www.frontiersin.org/journals/immunology/articles/10.)
Introduction: The influenza virus is recognized as the primary cause of human respiratory diseases, with the current influenza vaccine primarily offering strain-specific immunity and limited protection ... Juraszek J, Milder FJ, Yu X, Blokland S, van Overv. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches. PNAS Nexus. 2024 Oct 11;3(10):pgae462. Abstract
submitted by kickingbird at Oct, 25, 2024 from PNAS Nexus. 2024 Oct 11;3(10):pgae462 (via https://academic.oup.com/pnasnexus/article/3/10/pgae462/7818)
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ... Raju N, Kramer KJ, Cavallaro M, Diotti RA, Shiakol. Multiplexed Antibody Sequencing and Profiling of the Human Hemagglutinin-specific Memory B Cell Response following Influenza Vaccination. J Immunol. 2024 Oct 23:ji2400326. Abstract
submitted by kickingbird at Oct, 24, 2024 from J Immunol. 2024 Oct 23:ji2400326 (via https://journals.aai.org/jimmunol/article-abstract/doi/10.40)
Influenza virus is a highly contagious respiratory pathogen causing between 9.4 and 41 million infections per year in the United States in the last decade. Annual vaccination is recommended by the World ... Odin M, Schmeisser F, Soto J, Weir JP. A Rapid Virus-Free Method for Producing Influenza HA Immunogen Needed for Preparation of Influenza Vaccine Potency Antisera Reagents. Influenza Other Respir Viruses. 2024 Oct;18(10):e7. Abstract
submitted by kickingbird at Oct, 24, 2024 from Influenza Other Respir Viruses. 2024 Oct;18(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70024)
Background: The potency of inactivated and recombinant influenza vaccines is measured using the single-radial immunodiffusion (SRID) assay. The strain-specific antigen and antibody potency reagents required ... ?al??kan, D. M., Kumar, S., Hinse, S., Schughart,. Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Oct, 22, 2024 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The 2017/18 influenza season was characterized by unusual high numbers of severe infections and hospitalizations. Instead of influenza A viruses, this season was dominated by infections with influenza ... Lang, J., Helke, D., Kuryshko, M., & Abdelwhab, E.. Survivability of H5N1 Avian Influenza Virus in Homemade Yogurt, Cheese and Whey. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Oct, 22, 2024 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Influenza virus is typically associated with respiratory infections, but H5N1 in U.S. dairy cows raises public health concerns about milk by-products. We show that simple home recipes can inactivate H5N1 ... Ahrens, A. K., Pohlmann, A., Grund, C., Beer, M.,. Out of the blue: Detection of a unique highly pathogenic avian influenza virus of subtype H7N5 in Germany. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Oct, 22, 2024 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The current situation of an avian panzootic caused by highly pathogenic avian influenza viruses (HPAIV) of the goose/Guangdong lineage, subtype H5N1, clade 2.3.4.4b, is attracting significant attention ... He, J., Liu, J., Yan, Z., Chen, G., Liu, R., Yang,. Genetic Characterization and Receptor Binding analysis of a Novel H5N1 HPAI Virus with a H6Nx-Derived PA Gene in Guangdong, China. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Oct, 22, 2024 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Highly pathogenic avian influenza viruses (HPAIVs) of the H5 subtype pose a significant threat to global poultry industries and public health. Since their initial emergence in poultry in 1996 as the goose/Guangdong ... Wang J, Shen B, Yue L, Xu H, Chen L, Qian D, Dong. The Global Trend of Drug Resistant Sites in Influenza A Virus Neuraminidase Protein from 2011 to 2020. Microorganisms. 2024; 12(10):2056. Abstract
submitted by kickingbird at Oct, 22, 2024 from Microorganisms. 2024; 12(10):2056 (via https://www.mdpi.com/2076-2607/12/10/2056)
Influenza A virus (IAV) causes highly contagious respiratory disease worldwide, so prevention and control of IAV is extremely important. However, overuse of neuraminidase inhibitor (NAI) drugs leads to ... Yang X, Bist RB, Subedi S, Wu Z, Liu T, Paneru B,. A Machine Vision System for Monitoring Wild Birds on Poultry Farms to Prevent Avian Influenza. AgriEngineering. 2024; 6(4):3704-3718. Abstract
submitted by kickingbird at Oct, 22, 2024 from AgriEngineering. 2024; 6(4):3704-3718 (via https://www.mdpi.com/2624-7402/6/4/211)
The epidemic of avian influenza outbreaks, especially high-pathogenicity avian influenza (HPAI), which causes respiratory disease and death, is a disaster in poultry. The outbreak of HPAI in 2014–2015 ... Baybay Z, Montecillo A, Pantua A, Mananggit M, Rom. Molecular Characterization of a Clade 2.3.4.4b H5N1 High Pathogenicity Avian Influenza Virus from a 2022 Outbreak in Layer Chickens in the Philippines. Pathogens. 2024; 13(10):844. Abstract
submitted by kickingbird at Oct, 22, 2024 from Pathogens. 2024; 13(10):844 (via https://www.mdpi.com/2076-0817/13/10/844)
H5 subtype high-pathogenicity avian influenza (HPAI) viruses continue to devastate the poultry industry and threaten food security and public health. The first outbreak of H5 HPAI in the Philippines was ... Xu DW, Tate MD. Taking AIM at Influenza: The Role of the AIM2 Inflammasome. Viruses. 2024; 16(10):1535. Abstract
submitted by kickingbird at Oct, 22, 2024 from Viruses. 2024; 16(10):1535 (via https://www.mdpi.com/1999-4915/16/10/1535)
Influenza A viruses (IAV) are dynamic and highly mutable respiratory pathogens that present persistent public health challenges. Inflammasomes, as components of the innate immune system, play a crucial ... Galeone V, Lee C, Monaghan MT, Bauer DC, Wilson LO. Evolutionary Insights from Association Rule Mining of Co-Occurring Mutations in Influenza Hemagglutinin and Neuraminidase. Viruses. 2024; 16(10):1515. Abstract
submitted by kickingbird at Oct, 22, 2024 from Viruses. 2024; 16(10):1515 (via https://www.mdpi.com/1999-4915/16/10/1515)
Seasonal influenza viruses continuously evolve via antigenic drift. This leads to recurring epidemics, globally significant mortality rates, and the need for annually updated vaccines. Co-occurring mutations ... Hailiang Sun, etc.,al. Genetic evolution, phylodynamic and phylogeographic of H5Ny AIVs in mammals. Animals and Zoonoses. Abstract
submitted by kickingbird at Oct, 22, 2024 from Animals and Zoonoses (via https://www.sciencedirect.com/science/article/pii/S295024892)
The growing incidence of H5Ny virus infection in humans and mammals causes an increasing public health concern. To date, H5Ny virus infection in humans and mammals has been reported in 46 countries around ... Miyu Moriyama, etc.,al. [preprint]Intranasal hemagglutinin protein boosters induce robust mucosal immunity and cross-protection against influenza A viral challenge. https://doi.org/10.1101/2024.10.10.616291. Abstract
submitted by kickingbird at Oct, 20, 2024 from https://doi.org/10.1101/2024.10.10.616291 (via https://www.biorxiv.org/content/10.1101/2024.10.10.616291v1)
Licensed parenteral influenza vaccines induce systemic antibody responses and alleviate disease severity but do not efficiently prevent viral entry and transmission due to the lack of local mucosal immune ... Qiu Yu Huang, etc.,al. [preprint]Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography. https://doi.org/10.1101/2024.10.15.618557. Abstract
submitted by kickingbird at Oct, 20, 2024 from https://doi.org/10.1101/2024.10.15.618557 (via https://www.biorxiv.org/content/10.1101/2024.10.15.618557v1)
Influenza viruses are enveloped, negative sense single-stranded RNA viruses covered in a dense layer of glycoproteins. Hemagglutinin (HA) accounts for 80-90% of influenza glycoprotein and plays a role ... Zhang M, Zeng Y, Liu Q, Li F, Zhao J, Liu Z, Liu H. The H5N1-NS1 protein affects the host cell cycle and apoptosis through interaction with the host lncRNA PIK3CD-AS2. Virus Genes. 2024 Oct 18. Abstract
submitted by kickingbird at Oct, 20, 2024 from Virus Genes. 2024 Oct 18 (via https://link.springer.com/article/10.1007/s11262-024-02118-y)
Long noncoding RNAs (lncRNAs) are involved in the host antiviral response, but how host lncRNAs interact with viral proteins remains unclear. The NS1 protein of avian influenza viruses can affect the interferon-dependent ... Richard Webby, etc.,al. [preprint] Efficacy of oseltamivir and baloxavir against A(H5N1)-contaminated bovine milk in mice. https://doi.org/10.21203/rs.3.rs-5119512/v1. Abstract
submitted by kickingbird at Oct, 19, 2024 from https://doi.org/10.21203/rs.3.rs-5119512/v1 (via https://www.researchsquare.com/article/rs-5119512/v1)
Understanding the reliability of FDA-approved antivirals against A(H5N1) influenza viruses circulating in peridomestic species including dairy cows is critical to public health and pre-pandemic planning, ... 5584 items, 20/Page, Page[4/280][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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