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2021-4-20 4:59:21
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Wu Q, He J, Zhang WY, Zhao KF, Jin J, Yu JL, Chen. The contrasting relationships of relative humidity with influenza A and B in a humid subtropical region. Environ Sci Pollut Res Int. 2021 Mar 12.  Abstract  
submitted by kickingbird at Mar, 13, 2021 from Environ Sci Pollut Res Int. 2021 Mar 12 (via https://link.springer.com/article/10.1007/s11356-021-13107-1)
Influenza is an acute respiratory disease that seriously threatens public health. The occurrence of influenza has been proved to be related to a variety of meteorological factors. However, less attention ...

Peng J, Ran Y, Xie H, Deng L, Li C, Ling C. Sarco/Endoplasmic Reticulum Ca 2+ Transporting ATPase (SERCA) Modulates Autophagic, Inflammatory, and Mitochondrial Responses during Influenza A Virus Infection in Human Lung Cells. J Virol. 2021 Mar 10:JVI.00217-21.  Abstract  
submitted by kickingbird at Mar, 12, 2021 from J Virol. 2021 Mar 10:JVI.00217-21 (via https://jvi.asm.org/content/early/2021/03/09/JVI.00217-21)
Influenza A virus is an important human pathogen causing significant morbidity and mortality. Numerous host factors and cellular responses are dysregulated during influenza A virus infection. This includes ...

Wen S, Wu Z, Zhong S, Li M, Shu Y. Factors influencing the immunogenicity of influenza vaccines. Hum Vaccin Immunother. 2021 Mar 11:1-13.  Abstract  
submitted by kickingbird at Mar, 12, 2021 from Hum Vaccin Immunother. 2021 Mar 11:1-13 (via https://www.tandfonline.com/doi/abs/10.1080/21645515.2021.18)
Annual vaccination is the best prevention of influenza. However, the immunogenicity of influenza vaccines varies among different populations. It is important to fully identify the factors that may affect ...

Murphy-Schafer AR, Paust S. Divergent Mast Cell Responses Modulate Antiviral Immunity During Influenza Virus Infection. Front Cell Infect Microbiol. 2021 Feb 19;11:580679.  Abstract  
submitted by kickingbird at Mar, 10, 2021 from Front Cell Infect Microbiol. 2021 Feb 19;11:580679 (via https://www.frontiersin.org/articles/10.3389/fcimb.2021.5806)
Influenza A virus (IAV) is a respiratory pathogen that infects millions of people each year. Both seasonal and pandemic strains of IAV are capable of causing severe respiratory disease with a high risk ...

Labadie T, Grassin Q, Batéjat C, Manuguerra JC, Le. Monitoring Influenza Virus Survival Outside the Host Using Real-Time Cell Analysis. J Vis Exp. 2021 Feb 20;(168).  Abstract  
submitted by kickingbird at Mar, 9, 2021 from J Vis Exp. 2021 Feb 20;(168) (via https://www.jove.com/t/61133/monitoring-influenza-virus-surv)
Methods for virus particle quantification represent a critical aspect of many virology studies. Although several reliable techniques exist, they are either time-consuming or unable to detect small variations. ...

Overeem NJ, van der Vries E, Huskens J. A Dynamic, Supramolecular View on the Multivalent Interaction between Influenza Virus and Host Cell. Small. 2021 Mar 7:e2007214.  Abstract  
submitted by kickingbird at Mar, 9, 2021 from Small. 2021 Mar 7:e2007214 (via https://onlinelibrary.wiley.com/doi/10.1002/smll.202007214)
Understanding how influenza viruses traverse the mucus and recognize host cells is critical for evaluating their zoonotic potential, and for prevention and treatment of the disease. The surface of the ...

Na EJ, Kim YS, Lee SY, Kim YJ, Park JS, Oem JK. Genetic Characteristics of Avian Influenza Virus Isolated from Wild Birds in South Korea, 2019-2020. Viruses. 2021 Feb 27;13(3):381.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Viruses. 2021 Feb 27;13(3):381 (via https://www.mdpi.com/1999-4915/13/3/381)
Wild aquatic birds, a natural reservoir of avian influenza viruses (AIVs), transmit AIVs to poultry farms, causing huge economic losses. Therefore, the prevalence and genetic characteristics of AIVs isolated ...

Tiwary M, Rooney RJ, Liedmann S, LeMessurier KS, S. Eosinophil Responses at the Airway Epithelial Barrier during the Early Phase of Influenza A Virus Infection in C57BL/6 Mice. Cells. 2021 Feb 27;10(3):509.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Cells. 2021 Feb 27;10(3):509 (via https://www.mdpi.com/2073-4409/10/3/509)
Eosinophils, previously considered terminally differentiated effector cells, have multifaceted functions in tissues. We previously found that allergic mice with eosinophil-rich inflammation were protected ...

Kong M, Chen K, Zeng Z, Wang X, Gu M, Hu Z, Jiao X. The virulence modulator PA-X protein has minor effect on the pathogenicity of the highly pathogenic H7N9 avian influenza virus in mice. Vet Microbiol. 2021 Feb 26;255:109019.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Vet Microbiol. 2021 Feb 26;255:109019 (via https://www.sciencedirect.com/science/article/pii/S037811352)
PA-X is a novel discovered accessory protein encoded by the PA mRNA of the influenza A virus. Accumulated studies have demonstrated the crucial role of this protein in regulating the virulence of various ...

Mooij P, Stammes MA, Mortier D, Fagrouch Z, van Dr. Aerosolized Exposure to H5N1 Influenza Virus Causes Less Severe Disease Than Infection via Combined Intrabronchial, Oral, and Nasal Inoculation in Cynomolgus Macaques. Viruses. 2021 Feb 22;13(2):345.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Viruses. 2021 Feb 22;13(2):345 (via https://www.mdpi.com/1999-4915/13/2/345)
Infection with highly pathogenic avian H5N1 influenza virus in humans often leads to severe respiratory disease with high mortality. Experimental infection in non-human primates can provide additional ...

Pérez-Rubio G, Ponce-Gallegos MA, Domínguez-Mazzoc. Role of the Host Genetic Susceptibility to 2009 Pandemic Influenza A H1N1. Viruses. 2021 Feb 22;13(2):344.  Abstract  
submitted by kickingbird at Mar, 7, 2021 from Viruses. 2021 Feb 22;13(2):344 (via https://www.mdpi.com/1999-4915/13/2/344)
Influenza A virus (IAV) is the most common infectious agent in humans, and infects approximately 10-20% of the world's population, resulting in 3-5 million hospitalizations per year. A scientific literature ...

Phan T, Fay EJ, Lee Z, Aron S, Hu WS, Langlois RA. Segment-specific kinetics of mRNA, cRNA and vRNA accumulation during influenza infection. J Virol. 2021 Mar 3:JVI.02102-20.  Abstract  
submitted by kickingbird at Mar, 6, 2021 from J Virol. 2021 Mar 3:JVI.02102-20 (via https://jvi.asm.org/content/early/2021/03/01/JVI.02102-20)
Influenza A virus (IAV) is a segmented negative-sense RNA virus and is the cause of major epidemics and pandemics. The replication of IAV is complex, involving the production of three distinct RNA species; ...

Cohen AA, Yang Z, Gnanapragasam PNP, Ou S, Dam KA,. Construction, characterization, and immunization of nanoparticles that display a diverse array of influenza HA trimers. PLoS One. 2021 Mar 4;16(3):e0247963.  Abstract  
submitted by kickingbird at Mar, 6, 2021 from PLoS One. 2021 Mar 4;16(3):e0247963 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Current influenza vaccines do not elicit broadly protective immune responses against multiple strains. New strategies to focus the humoral immune response to conserved regions on influenza antigens are ...

Holzer B, Rijal P, McNee A, Paudyal B, Martini V,. Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans. PLoS Pathog. 2021 Mar 4;17(3):e1009330.  Abstract  
submitted by kickingbird at Mar, 6, 2021 from PLoS Pathog. 2021 Mar 4;17(3):e1009330 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Pigs are natural hosts for the same subtypes of influenza A viruses as humans and integrally involved in virus evolution with frequent interspecies transmissions in both directions. The emergence of the ...

Kim EH, Kim YL, Kim SM, Yu KM, Casel MAB, Jang SG,. Pathogenic Assessment of Avian Influenza Viruses in Migratory Birds. Emerg Microbes Infect. 2021 Mar 5:1-40.  Abstract  
submitted by kickingbird at Mar, 6, 2021 from Emerg Microbes Infect. 2021 Mar 5:1-40 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Several subtypes of avian influenza (AI) viruses have caused human infections in recent years; however, there is a severe knowledge gap regarding the capacity of wild bird viruses to infect mammals. To ...

Sun H, Li F, Liu Q, Du J, Liu L, Sun H, Li C, Liu. Mink is a highly susceptible host species to circulating human and avian influenza viruses. Emerg Microbes Infect. 2021 Mar 3:1-34.  Abstract  
submitted by kickingbird at Mar, 5, 2021 from Emerg Microbes Infect. 2021 Mar 3:1-34 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Pandemic influenza, typically caused by reassortment of human and avian influenza viruses, can result in severe or fatal infections in humans. Timely identification of potential pandemic viruses must be ...

Hong Y, Truong AD, Lee J, Vu TH, Lee S, Song KD, L. Exosomal miRNA profiling from H5N1 avian influenza virus-infected chickens. Vet Res. 2021 Mar 3;52(1):36.  Abstract  
submitted by kickingbird at Mar, 5, 2021 from Vet Res. 2021 Mar 3;52(1):36 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Exosomes are membrane vesicles containing proteins, lipids, DNA, mRNA, and micro RNA (miRNA). Exosomal miRNA from donor cells can regulate the gene expression of recipient cells. Here, Ri chickens were ...

Luo Z, Girton AW, Heaton BE, Heaton NS. Engineered influenza virions reveal the contributions of non-hemagglutinin structural proteins to vaccine mediated protection. J Virol. 2021 Mar 3:JVI.02021-20.  Abstract  
submitted by kickingbird at Mar, 5, 2021 from J Virol. 2021 Mar 3:JVI.02021-20 (via https://jvi.asm.org/content/early/2021/03/01/JVI.02021-20)
The development of improved and universal anti-influenza vaccines would represent a major advance in the protection of human health. In order to facilitate the development of such vaccines, understanding ...

Tran GVQ, Kleinehr J, Preugschas HF, Anhlan D, Moh. Nonsense-mediated mRNA decay does not restrict influenza A virus propagation. Cell Microbiol. 2021 Mar 2.  Abstract  
submitted by kickingbird at Mar, 4, 2021 from Cell Microbiol. 2021 Mar 2 (via https://onlinelibrary.wiley.com/doi/10.1111/cmi.13323)
Nonsense-mediated mRNA decay (NMD) was identified as a process to degrade flawed cellular messenger RNA (mRNA). Within the last decades it was also shown that NMD carries virus-restricting capacities and ...

Zhang T, Li R, Zhong P, Chang J, Xu B. Detection of novel reassortant H9N2 avian influenza viruses in wild birds in Jiangxi Province, China. Vet Med Sci. 2021 Mar 3.  Abstract  
submitted by kickingbird at Mar, 4, 2021 from Vet Med Sci. 2021 Mar 3 (via https://onlinelibrary.wiley.com/doi/10.1002/vms3.391)
The five avian influenza A/H9N2 viruses isolated from wild birds in Jiangxi, China in 2015 are novel reassortants which most likely evolved from multiple lineages. They shared a high similarity with isolates ...

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