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2024-3-29 7:35:07
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Li ZA, Bajpai AK, Wang R, Liu Y, Webby RJ, Wilk E,. Systems Genetics of Influenza A Virus-infected Mice Identifies TRIM21 as a Critical Regulator of Pulmonary Innate Immune Response. Virus Res. 2024 Feb 6:199335.  Abstract  
submitted by kickingbird at Feb, 9, 2024 from Virus Res. 2024 Feb 6:199335 (via https://pubmed.ncbi.nlm.nih.gov/38331257/)
Tripartite motif 21 (TRIM21) is a cytosolic Fc receptor that targets antibody-bound, internalized pathogens for destruction. Apart from this intrinsic defense role, TRIM21 is implicated in autoimmune diseases, ...

Krischuns T, Arragain B, Isel C, Paisant S, Budt M. The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun. 2024 Feb 5;15(1):1064.  Abstract  
submitted by kickingbird at Feb, 8, 2024 from Nat Commun. 2024 Feb 5;15(1):1064 (via https://www.nature.com/articles/s41467-024-45205-2)
The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear phosphoprotein 32 (ANP32), which drives its conformation and ...

Li X, Li Y, Shang X, Kong H. A sequence-based machine learning model for predicting antigenic distance for H3N2 influenza virus. Front Microbiol. 2024 Jan 19;15:1345794.  Abstract  
submitted by kickingbird at Feb, 7, 2024 from Front Microbiol. 2024 Jan 19;15:1345794 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Introduction: Seasonal influenza A H3N2 viruses are constantly changing, reducing the effectiveness of existing vaccines. As a result, the World Health Organization (WHO) needs to frequently update the ...

Liu K, Qi X, Bao C, Wang X, Liu X. Novel H10N3 avian influenza viruses: a potential threat to public health. Lancet Microbe. 2024 Jan 31:S2666-5247(23)00409-3.  Abstract  
submitted by kickingbird at Feb, 4, 2024 from Lancet Microbe. 2024 Jan 31:S2666-5247(23)00409-3 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Novel H10N3 avian influenza viruses have been frequently isolated from poultry across various regions of China (including Jiangsu, Zhejiang, Fujian, and other provinces) in recent years and have caused ...

Gu G, Liu C, Lee SH, Chun Choi LS, Wilson MT, Pfei. Detection of a reassortant swine H1N2 influenza A virus from pigs in Hong Kong. Virol Sin. 2024 Feb 1:S1995-820X(24)00009-9.  Abstract  
submitted by kickingbird at Feb, 4, 2024 from Virol Sin. 2024 Feb 1:S1995-820X(24)00009-9 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A viruses (IAVs) are responsible for significant respiratory illnesses in humans and a broad range of animal species. Repeated outbreaks and the rapid spread of genetically and antigenically ...

Kenmoe S, Takuissu GR, Ebogo-Belobo JT, Kengne-Ndé. A systematic review of influenza virus in water environments across human, poultry, and wild bird habitats. Water Res X. 2023 Dec 13;22:100210.  Abstract  
submitted by kickingbird at Feb, 3, 2024 from Water Res X. 2023 Dec 13;22:100210 (via https://www.sciencedirect.com/science/article/pii/S258991472)
Influenza, a highly contagious acute respiratory disease, remains a major global health concern. This study aimed to comprehensively assess the prevalence of influenza virus in different aquatic environments. ...

Li H, Sun H, Tao M, Han Q, Yu H, Li J, Lu X, Tong. Recombinant parainfluenza virus 5 expressing clade 2.3.4.4b H5 hemagglutinin protein confers broad protection against H5Ny influenza viruses. J Virol. 2024 Feb 2:e0112923.  Abstract  
submitted by kickingbird at Feb, 3, 2024 from J Virol. 2024 Feb 2:e0112923 (via https://journals.asm.org/doi/10.1128/jvi.01129-23)
The global circulation of clade 2.3.4.4b H5Ny highly pathogenic avian influenza viruses (HPAIVs) in poultry and wild birds, increasing mammal infections, continues to pose a public health threat and may ...

Curran SJ, Griffin EF, Ferreri LM, Kyriakis CS, Ho. Swine influenza A virus isolates containing the pandemic H1N1 origin matrix gene elicit greater disease in the murine model. Microbiol Spectr. 2024 Feb 1:e0338623.  Abstract  
submitted by kickingbird at Feb, 3, 2024 from Microbiol Spectr. 2024 Feb 1:e0338623 (via https://journals.asm.org/doi/10.1128/spectrum.03386-23)
Since the 1990s, endemic North American swine influenza A viruses (swFLUAVs) contained an internal gene segment constellation, the triple reassortment internal gene (TRIG) cassette. In 2009, the H1N1 pandemic ...

Rowe T, Davis W, Wentworth DE, Ross T. Differential interferon responses to influenza A and B viruses in primary ferret respiratory epithelial cells. J Virol. 2024 Jan 31:e0149423.  Abstract  
submitted by kickingbird at Feb, 1, 2024 from J Virol. 2024 Jan 31:e0149423 (via https://journals.asm.org/doi/10.1128/jvi.01494-23)
Influenza B viruses (IBV) cocirculate with influenza A viruses (IAV) and cause periodic epidemics of disease, yet antibody and cellular responses following IBV infection are less well understood. Using ...

Na L, Sun L, Yu M, Zhang Y, Zhang Y, Zhang Z, Zhan. Avian ANP32A incorporated in avian influenza A virions promotes interspecies transmission by priming early viral replication in mammals. Sci Adv. 2024 Feb 2;10(5):eadj4163.  Abstract  
submitted by kickingbird at Feb, 1, 2024 from Sci Adv. 2024 Feb 2;10(5):eadj4163 (via https://www.science.org/doi/10.1126/sciadv.adj4163)
Species-specific differences in acidic nuclear phosphoprotein 32 family member A (ANP32A) determine the restriction of avian-signature polymerase in mammalian cells. Mutations that evade this restriction, ...

Jia Y, Yang J, Wang Z, Du Y, Cui J, Wang L, Guo F,. Genetic properties and pathogenicity of a novel reassortant H10N5 influenza virus from wild birds. Arch Virol. 2017 May;162(5):1349-1353.  Abstract  
submitted by kickingbird at Jan, 31, 2024 from Arch Virol. 2017 May;162(5):1349-1353 (via https://link.springer.com/article/10.1007/s00705-017-3234-3)
In this study, we analyzed the genome of a H10N5 influenza virus from wild birds. This virus was identified as a novel reassortant virus with internal genes from multiple subtypes and of distinct origins. ...

Wang N, Zou W, Yang Y, Guo X, Hua Y, Zhang Q, Zhao. Complete genome sequence of an H10N5 avian influenza virus isolated from pigs in central China. J Virol. 2012 Dec;86(24):13865-6.  Abstract  
submitted by kickingbird at Jan, 31, 2024 from J Virol. 2012 Dec;86(24):13865-6 (via https://journals.asm.org/doi/10.1128/jvi.02687-12)
An avian H10N5 influenza virus, A/swine/Hubei/10/2008/H10N5, was isolated from pigs in the Hubei Province of central China. Homology and phylogenetic analyses of all eight gene segments demonstrated that ...

Seekings AH, Liang Y, Warren CJ, Hjulsager CK, Tho. Transmission dynamics and pathogenesis differ between pheasants and partridges infected with clade 2.3.4.4b H5N8 and H5N1 high-pathogenicity avian influenza viruses. J Gen Virol. 2024 Jan;105(1)..  Abstract  
submitted by kickingbird at Jan, 31, 2024 from J Gen Virol. 2024 Jan;105(1). (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
During the UK 2020-2021 epizootic of H5Nx clade 2.3.4.4b high-pathogenicity avian influenza viruses (HPAIVs), high mortality occurred during incursions in commercially farmed common pheasants (Phasianus ...

Wang X, Kim KW, Walker G, Stelzer-Braid S, Scotch. Genome characterization of influenza A and B viruses in New South Wales, Australia, in 2019: A retrospective study using high-throughput whole genome sequencing. Influenza Other Respir Viruses. 2024 Jan;18(1):e13.  Abstract  
submitted by kickingbird at Jan, 31, 2024 from Influenza Other Respir Viruses. 2024 Jan;18(1):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13252)
Background: During the 2019 severe influenza season, New South Wales (NSW) experienced the highest number of cases in Australia. This study retrospectively investigated the genetic characteristics of influenza ...

Heider A, Wedde M, Weinheimer V, D?llinger S, Mona. Characteristics of two zoonotic swine influenza A(H1N1) viruses isolated in Germany from diseased patients. Int J Med Microbiol. 2024 Jan 24;314:151609.  Abstract  
submitted by kickingbird at Jan, 30, 2024 from Int J Med Microbiol. 2024 Jan 24;314:151609 (via https://www.sciencedirect.com/science/article/pii/S143842212)
Interspecies transmission of influenza A viruses (IAV) from pigs to humans is a concerning event as porcine IAV represent a reservoir of potentially pandemic IAV. We conducted a comprehensive analysis ...

Huang Xiner, Zhou Xue, Yang Sitian, Hu Minhao, Yu. Molecular evolution of avian influenza A (H9N2) virus in external environment in Anhui, 2019-2021. DOI: 10.3784/jbjc.202303150100.  Abstract  
submitted by kickingbird at Jan, 29, 2024 from DOI: 10.3784/jbjc.202303150100 (via http://www.jbjc.org/cn/article/doi/10.3784/jbjc.202303150100)
Objective To analyze the genetic evolution characteristics of avian influenza A (H9N2) virus in external environment in Anhui province from 2019 to 2021.Methods A total of 383 positive samples of avian ...

Soos BL, Ballinger A, Weinstein M, Foreman H, Gram. Color-Flu Fluorescent Reporter Influenza A Viruses Allow for In Vivo Studies of Innate Immune Function in Zebrafish. Viruses. 2024 Jan 20;16(1):155.  Abstract  
submitted by kickingbird at Jan, 27, 2024 from Viruses. 2024 Jan 20;16(1):155 (via https://www.mdpi.com/1999-4915/16/1/155)
Influenza virus infection can cause severe respiratory disease and is estimated to cause millions of illnesses annually. Studies on the contribution of the innate immune response to influenza A virus (IAV) ...

Kolosova NP, Boldyrev ND, Svyatchenko SV, Danilenk. An Investigation of Severe Influenza Cases in Russia during the 2022-2023 Epidemic Season and an Analysis of HA-D222G/N Polymorphism in Newly Emerged and Dominant Clade 6B.1A.5a.2a A(H1N1)pdm09 Viruse. Pathogens. 2023 Dec 19;13(1):1.  Abstract  
submitted by kickingbird at Jan, 27, 2024 from Pathogens. 2023 Dec 19;13(1):1 (via https://www.mdpi.com/2076-0817/13/1/1)
In Russia, during the COVID-19 pandemic, a decrease in influenza circulation was initially observed. Influenza circulation re-emerged with the dominance of new clades of A(H3N2) viruses in 2021-2022 and ...

Cheng J, Tao J, Li B, Shi Y, Liu H. The lncRNA HCG4 regulates the RIG-I-mediated IFN production to suppress H1N1 swine influenza virus replication. Front Microbiol. 2024 Jan 11;14:1324218..  Abstract  
submitted by kickingbird at Jan, 27, 2024 from Front Microbiol. 2024 Jan 11;14:1324218. (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1324)
Influenza A virus (IAV) non-structural protein 1 (NS1) is a virulence factor that allows the virus to replicate efficiently by suppressing host innate immune responses. Previously, we demonstrated that ...

Ao J, Ma AX, Li J, Wang CY, Fu DD, Du L, Yu C, Liu. Real-Time Dissection of the Exosome Pathway for Influenza Virus Infection. ACS Nano. 2024 Jan 25.  Abstract  
submitted by kickingbird at Jan, 26, 2024 from ACS Nano. 2024 Jan 25 (via https://pubs.acs.org/doi/10.1021/acsnano.3c11309)
Exosomes play an important role in the spread of viral infections and immune escape. However, the exact ability and mechanisms by which exosomes produced during viral infections (vExos) infect host cells ...

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